Navigation On Topic Complete Directory About Us Add-site Link to Us MerchantStore Shopping	Advertisement 202 Health - Alzheimer Resources 3 biomarkers in spinal fluid appear helpful to classify patients with Alzheimer's disease A "signature" consisting of three biomarkers in the cerebrospinal fluid was present in 90 percent of patients who had been diagnosed with Alzheimer's disease but also was found in more than one-third of cognitively normal older adults, according to a report in the August issue of Archives of Neurology, one of the JAMA/Archives journals. View Source August 9, 2010 Provides Information 25th Alzheimer's Disease International conference: Focus on new treatment developments "What's new" in Alzheimer's disease medical treatments and diagnosis is the focus of the first day's plenary sessions at the 25th International Conference of Alzheimer's Disease International (ADI), March 11, 2010 at the Grand Hotel Palace, Thessaloniki, Greece. View Source March 4, 2010 Provides Information A A chemical to make brain cells grow: Mental decline thwarted in aging rats Scientists have discovered a compound that restores the capacity to form new memories in aging rats, likely by improving the survival of newborn neurons in the brain's memory hub. The research, funded in part by the National Institutes of Health, has turned up clues to a neuroprotective mechanism that could lead to a treatment for Alzheimer's disease. View Source July 8, 2010 Provides Information AAN issues guideline on when people with Alzheimer's disease should stop driving The American Academy of Neurology has issued a new guideline to help determine when people with Alzheimer's disease or another type of dementia should stop driving. View Source April 12, 2010 Provides Information Adeona completes 50% enrollment in Part 2 CopperProof-2 study of oral zinc cysteine for Alzheimer's Disease Adeona Pharmaceuticals, Inc. announced the completion of 50% enrollment in Part 2 of its clinical study, A Prospective, Randomized, Double Blind Trial of a Novel Oral Zinc Cysteine Preparation in Alzheimer's Disease (CopperProof-2). View Source June 7, 2010 Provides Information Advanced Nanotechnology Helps Scientists Investigate on Truncated Peptides Some current therapies being investigated for Alzheimer's disease may cause further neural degeneration and cell death, according to a breakthrough discovery by UC San Diego researchers. View Source April 2, 2010 Provides Information Aging and Alzheimer's disease: Novel brain imaging technologies help create new insights The emergence of multiple new brain imaging technologies and the combined application of these new approaches is helping to create new insights into aging and Alzheimer's disease. One of the hallmarks of Alzheimer's disease is the deposition of amyloid beta protein in clumps or "plaques" within the brain. These plaques can be measured in humans with PET scans that use a chemical marker or radiotracer called 11C-PIB. View Source March 16, 2010 Provides Information Amorfix Life Sciences uses A(4) test to detect accumulation of Abeta in mouse models of AD Amorfix Life Sciences, a company focused on treatments and diagnostics for misfolded protein diseases including Alzheimer's disease (AD), has used its A(4) test to compare the rate of accumulation of aggregated Abeta in the brain tissue of various mouse models of AD. Amorfix presented this new data at the International Conference on Alzheimer's Disease (ICAD 2010) this week. View Source July 13, 2010 Provides Information Alcohol consumption may protect against risk of Alzheimer's Disease, particularly in female nonsmokers Knowledge regarding environmental factors influencing the risk of Alzheimer's disease is surprisingly scarce, despite substantial research in this area. In particular, the roles of smoking and alcohol consumption still remain controversial. A new study published this month in the Journal of Alzheimer's Disease suggests a protective effect of alcohol consumption on the risk of Alzheimer's disease, particularly in women who do not smoke. View Source May 24, 2010 Provides Information Alzheimer's and open source medicine We think of open source as being a process for developing software. It’s also a process for developing cures. View Source August 16, 2010 Provides Information Alzheimer's-Associated Protein May Be Part of the Innate Immune System Amyloid-beta protein -- the primary constituent of the plaques found in the brains of Alzheimer's disease patients -- may be part of the body's first-line system to defend against infection. View Source March 3, 2010 Provides Information Alzheimer's Association The Alzheimer's Association is the leading voluntary health organization in Alzheimer care, support and research. View Source   Provides a Service Alzheimer’s Brain Protein May Provide Target for Treating Mental Retardation From the perspective of neuroscientists, Alzheimer's disease and Down syndrome have at least one thing in common: patients with both diseases have an accumulation of ß-amyloid protein in their brains. Rockefeller University scientists now provide evidence that drugs which help reduce the level of ß-amyloid in the brains of Alzheimer's patients may also work to treat mental retardation in Down syndrome. View Source June 13, 2010 Provides Information Alzheimer's disease awareness event aims to raise over $100,000 for Alzheimer Society of Montreal It's on a path full of history and collective memories that more than 500 walkers will gather, on Sunday, May 30th, for the fourth edition of the RONA Walk for Memories. This Alzheimer's disease awareness event, which will take place on the Quays of the Old Port and in the streets of the Old Montreal, aims to raise over $100,000 for the Alzheimer Society of Montreal! View Source May 31, 2010 Provides Information Alzheimer's imaging study identifies changes in brain's white matter Scientists at the University of Kentucky's College of Medicine have identified changes in the brains of normal individuals at high risk for Alzheimer's disease that could prove important for early detection of the disease. View Source June 28, 2010 Provides Information Alzheimer's memory problems originate with protein clumps floating in the brain, not amyloid plaques Using a new mouse model of Alzheimer's disease, researchers at Mount Sinai School of Medicine have found that Alzheimer's pathology originates in Amyloid-Beta (Abeta) oligomers in the brain, rather than the amyloid plaques previously thought by many researchers to cause the disease. View Source April 27, 2010 Provides Information Alzheimer's rat created for human research Prof. Claudio Cuello at McGill University and his collaborators have genetically manipulated rats that can emulate Alzheimer's disease in humans, enabling research that will include the development of new treatments. View Source March 29, 2010 Provides Information Alzheimer's Therapies Unproven, but Patient Respect Goes a Long Way Therapies to prevent or slow Alzheimer's disease - including mental stimulation, exercise, and dietary supplements - have not been demonstrated to work, according to an independent panel of the U.S. National Institutes of Health. View Source May 19, 2010 Provides Information Amorfix Life Sciences detects AD-associated aggregated Beta-amyloid in blood plasma Amorfix Life Sciences, a company focused on treatments and diagnostics for misfolded protein diseases such as Alzheimer's disease (AD), announced today the detection of the AD-associated aggregated Beta-amyloid (ABeta), the hallmark of AD, in the blood from the most-frequently-used animal model of AD. The assay detects both oligomeric and fibrillar aggregates of ABeta, which are generally considered to be the toxic forms and major contributors to brain dysfunction in AD. View Source May 4, 2010 Provides Information Amorfix partners with reMYND to offer A4 amyloid testing services Amorfix Life Sciences Ltd. and reMYND NV today announced the signing of a partnership agreement to offer the Amorfix A4 amyloid testing service to reMYND's contract research clients. reMYND's contract research business offers an extensive portfolio of preclinical in-vivo efficacy, pharmacokinetic and safety testing of experimental Alzheimer therapies using proprietary mouse models of Alzheimer's disease. View Source July 6, 2010 Provides Information Anesthesia increases risk of developing Alzheimer's disease in patients with genetic predisposition The use of repetitive anesthesia with isoflurane (one of the most common anesthetics by inhalation) increases the risk of developing changes similar to those observed in AD brains in mice with mutations of the amyloid precursor protein. This is the main conclusion of Spanish researchers coordinated by Doctors Maria Angeles Mena and Justo Garcia de Yebenes, from Centro de Investigacion Biomedica en Red de Enfermedades Neurodegenerativas. The work has been published in the Journal of Alzheimer's Disease. View Source March 24, 2010 Provides Information Antibiotics improve survival but not comfort for terminal dementia patients with pneumonia A new study by scientists at the Institute for Aging Research of Hebrew SeniorLife says the use of antibiotics to treat pneumonia in patients with terminal dementia presents a "doubled-edged" sword for health-care providers and family members, finding that antibiotics may prolong survival for these patients, but do not improve their comfort. View Source July 12, 2010 Provides Information Antihypertensive drugs may protect against Alzheimer's disease Researchers at Mount Sinai School of Medicine have found that the drug carvedilol, currently prescribed for the treatment of hypertension, may lessen the degenerative impact of Alzheimer's disease and promote healthy memory functions. View Source June 24, 2010 Provides Information Apple juice improves behavior but not cognition in Alzheimer's patients Apple juice can be a useful supplement for calming the declining moods that are part of the normal progression of moderate-to-severe Alzheimer's Disease (AD), according to a study in American Journal of Alzheimer's Disease and Other Dementias (AJADD), published by SAGE. View Source June 14, 2010 Provides Information Artificial Neural Networks Help Identify Predisposing Factors for Conversion of Mild Cognitive Impairment to Alzheimer’s Disease Mild cognitive impairment (MCI) is often considered an early symptom of Alzheimer's disease (AD). An analysis of genetic risk factors predisposing to MCI is critical for accessing individual predisposition and reliably evaluating the effectiveness of early treatment. In a groundbreaking study published in the February 2010 issue of the Journal of Alzheimer's Disease investigators successfully used artificial neural networks (ANNs) to help understand the causal relation between multiple factors and the occurrence of neurodegenerative disorders. View Source March 2, 2010 Provides Information Association of Genetic Factors and Brain Imaging Findings in Alzheimer's Disease By investigating the association between genetic loci related to Alzheimer's disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer's disease and also may have identified new genetic risk factors for further study, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals. View Source June 16, 2010 Provides Information Augmentation with ketone bodies improves cognitive function in AD patients Accera, Inc., a biotechnology company delivering breakthrough therapies in central nervous system diseases, announced data which showed that augmentation with ketone bodies significantly improved cognitive function in Alzheimer's disease (AD) patients. View Source March 10, 2010 Provides Information Australian study to reduce Alzheimer’s symptoms through exercise A new study will test whether physical activity can improve the memory and wellbeing of sufferers of Alzheimer’s Disease (AD). View Source April 20, 2010 Provides Information B 'Beer belly' linked to Alzheimer's disease People who carry a lot of weight around their middle are at increased risk of developing dementia, say researchers. View Source May 20, 2010 Provides Information BELLUS Health initiates Phase I clinical study for NRM8499 BELLUS Health Inc. announced today that, on March 30, 2010, the Company initiated a Phase I clinical study for NRM8499, a prodrug of tramiprosate. NRM8499 is intended for the treatment of Alzheimer's disease. The randomized, double-blind, placebo-controlled study will investigate the safety, tolerability and pharmacokinetic profile of NRM8499 in a group of up to 84 young and elderly healthy subjects. View Source April 1, 2010 Provides Information Best Friends Bill of Rights outlines 12 rules to help caregivers enhance lives of patients with Alzheimer's disease Caring for someone with Alzheimer's or dementia can be a daunting task, even for the most experienced of professionals working with seniors daily in assisted living and memory care. View Source July 1, 2010 Provides Information Bigger molecular-sized anesthetics do not promote amyloid beta peptide micro-aggregation Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions of people worldwide and has become a major global concern. Uncontrolled oligomerization (aggregation) of Aβ peptide is the hallmark of AD and it is believed to be causally related to AD pathomechanism. Intensive research (biophysical, animal model and clinical) is underway to investigate the cause of this unexplained aggregation of Aβ peptide, which is probably triggered by some agent or process in predisposed individuals, and subsequently to trace the molecular pathways involved in the phenomenon. View Source April 21, 2010 Provides Information Boehringer Ingelheim Select a Nanobody Lead Candidate to Develop Therapies for Alzheimer's Ablynx has announced that Boehringer Ingelheim has selected a Nanobody lead candidate for further development for the treatment of Alzheimer's disease. This is the first lead candidate emerging from the Alzheimer's disease collaboration between Ablynx and Boehringer Ingelheim, and will result in a €2 million milestone payment to Ablynx. View Source May 25, 2010 Provides Information Brain exercises may slow cognitive decline initially, but speed up dementia later New research shows that mentally stimulating activities such as crossword puzzles, reading and listening to the radio may, at first, slow the decline of thinking skills but speed up dementia later in old age. View Source September 1, 2010 Provides Information Brain plaques may explain higher risk of Alzheimer's based on mom's history A family history of Alzheimer's is one of the biggest risk factors for developing the memory-robbing disease, which affects more than 5 million Americans and is the most common form of senile dementia. Now an international collaboration led by NYU Langone Medical Center researchers has found the likely basis for this heightened familial risk—especially from the maternal side. View Source March 15, 2010 Provides Information Brain Stimulation Technique Boosts Language Ability in Alzheimer's Patients A brain stimulation technique, known as repetitive transcranial magnetic stimulation, boosts the language ability of patients with Alzheimer's disease, suggests preliminary research, published online in the Journal of Neurology, Neurosurgery and Psychiatry. View Source June 25, 2010 Provides Information Brain to behaviour How do you know where your keys are? Why do we develop habits and what influences our judgement? Throughout the Cardiff University, psychologists, behavioural geneticists and neurologists are working together to understand the fundamental mechanisms of learning and memory. Their work has implications for understanding brain function and changes as well as giving vital insight into neurological conditions such as Alzheimer's disease and schizophrenia. View Source August 23, 2010 Provides Information C Can Meditation Reverse Memory Loss? Study Shows Improvement on Memory Tests After Practicing Meditation for 8 Weeks View Source March 3, 2010 Provides Information Cancer drug inspires new Alzheimer's approach Leukemia medication may keep dementia brain plaques from developing View Source September 1, 2010 Provides Information Carnegie Mellon will test ability of embedded sensors to detect onset of dementia, infirmity Carnegie Mellon University researchers in the Quality of Life Technology Center (QoLTC) will embed wireless sensors in the residences of about 50 older adults who live alone to see if they can detect subtle changes in everyday activities that indicate the onset of dementia or physical infirmities. View Source March 3, 2010 Provides Information Children of Alzheimer's sufferers want to know their risk Greg Kalkwarf was a teenager when his grandfather told him and his brother, with increasing anger and frustration, "Dean, get out there and milk the cows!" View Source July 16, 2010 Provides Information Chronic Pain: Does Vitamin D Help? Researchers are exploring a possible link between low levels of vitamin D and chronic pain. View Source May 25, 2010 Provides Information Closer to a cure: PET imaging tracks early stages of Alzheimer's Research unveiled at SNM's 57th Annual Meeting shows that scientists are drawing closer to documenting the progression of a disease process believed to cause Alzheimer's disease. This research could eventually lead to life-saving preventative measures for millions of patients who suffer from this chronic neurodegenerative disorder. View Source June 7, 2010 Provides Information Cognition Therapeutics receives grant to develop small-molecule drug candidate for Alzheimer's disease The Alzheimer's Drug Discovery Foundation (ADDF) announced today that it has awarded a grant of $228,668 to Cognition Therapeutics (CogRx) to develop small molecule drugs that block the action of the toxic "oligomers" thought responsible for Alzheimer's disease (AD). View Source August 19, 2010 Provides Information Common Alzheimer's medication helps skills necessary for safe driving A promising study from Rhode Island Hospital demonstrated that cholinesterase inhibitors (ChEI), a type of medication often prescribed for Alzheimer's disease (AD), improved some cognitive skills in patients with mild AD - skills that are necessary for driving. Findings from the study showed that after being treated with a ChEI, AD patients improved in some computerized tests of executive function and visual attention, including a simulated driving task. View Source June 9, 2010 Provides Information Computer algorithm, MRI used to tap memory A computer algorithm, functional Magnetic Resonance Imaging (fMRI), and neuroscientists working together have been able to identify what people are remembering by measuring blood flow levels, according to new research out of the University College London. View Source March 11, 2010 Provides Information Contrast Agent for Alzheimer's Shows Promise in Phase III Trial We had previously reported on Avid Radiopharmaceuticals developing a contrast agent florbetapir to be used with positron emission tomography (PET) imaging to detect Alzheimer's. Now in a Phase III Image-to-Autopsy trial, florbetapir shows promise as a predictive biomarker for diagnosing and monitoring disease progression. View Source April 16, 2010 Provides Information D Deep Brain Stimulation shows promise for patients with Alzheimer's In a world first, Dr. Andres M. Lozano and his team at Toronto Western Hospital has shown using Deep Brain Stimulation (DBS) on patients with early signs of Alzheimer's disease is safe and may help improve memory. View Source August 4, 2010 Provides Information Delirium in older patients associated with greater risk of death, dementia and institutionalization A review and analysis of previous research indicates that delirium in elderly patients is associated with an increased risk of death, dementia, and institutionalization, independent of age, co-existing illnesses or illness severity, according to a study in the July 28 issue of JAMA. View Source July 27, 2010 Provides Information Dementia takes away the meaning of flavors Flavour is literally the spice of life and for many people life without the pleasures of the table would be unthinkable. Yet just this aspect of everyday life is vulnerable in certain degenerative dementias, with patients developing abnormal eating behaviours including changes in food preferences, faddism and pathological sweet tooth. New research has revealed evidence that these behaviours are linked to a loss of meaning for flavours, as reported in the June 2010 issue of Elsevier's Cortex. View Source May 10, 2010 Provides Information Depression may nearly double risk of dementia A new study shows that having depression may nearly double your risk of developing dementia later in life. The research will be published in the July 6, 2010, issue of Neurology, the medical journal of the American Academy of Neurology. View Source July 5, 2010 Provides Information Distinguishing 'Senior Moments' from Alzheimer's With the help of volunteers aged 18 to 89, UC Irvine researchers have identified for the first time in humans a long-hidden part of the brain called the perforant path. Scientists have struggled for decades to locate the tiny passage, which is believed to deteriorate gradually as part of normal aging and far more quickly due to Alzheimer's disease. View Source August 10, 2010 Provides Information Drug companies share data to speed brain research In an unusual step, a dozen competing drug companies have agreed to share data on thousands of Alzheimer's patients in hopes that the extra information will spark new ideas for treatments. View Source June 11, 2010 Provides Information Drug That Extends Life Span Prevents Alzheimer's Deficits If research results continue to be repeated and are turned into clinical trials, a drug already approved for some uses could be marshaled -- sooner than we expect -- to prevent Alzheimer's disease in humans and improve health to the end of life. View Source April 2, 2010 Provides Information E Early Alzheimer's Identification Method Discovered Abnormal brain images combined with examination of the composition of the fluid that surrounds the spine may offer the earliest signs identifying healthy older adults at risk of developing Alzheimer's disease, well before cognitive problems emerge, a study by researchers at UC Davis has found. View Source July 9, 2010 Provides Information Eating foods rich in vitamin E associated with lower dementia risk Consuming more vitamin E through the diet appears to be associated with a lower risk of dementia and Alzheimer's disease, according to a report in the July issue of Archives of Neurology. View Source July 12, 2010 Provides Information Education slows down development of dementia: Researchers Researchers have discovered that education not only delays the early symptoms of dementia, but can also slow down the development of the disease - a finding that could result in faster diagnosis and treatment of dementia, reveals a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden. View Source May 31, 2010 Provides Information Eli Lilly Stops Development Of An Alzheimer's Drug Eli Lilly & Co. said it halted development of an experimental drug for Alzheimer's disease after studies showed it worsened patients' conditions and was associated with an increased risk of skin cancer. View Source August 17, 2010 Provides Information Eliminating Diabetes and Depression, and Boosting Education, Most Likely to Ward Off Dementia Eliminating diabetes and depression, as well as increasing education and fruit and vegetable consumption, are likely to have the biggest impact on reducing levels of dementia in the coming years, should no effective treatment be found, concludes a study published on the British Medical Journal website. View Source August 6, 2010 Provides Information Emotional flatness can be mistaken for depression in Alzheimer's patients Watching a loved one struggle with Alzheimer's disease can be a painful process, but for the patient, the experience may be a muted one. View Source July 6, 2010 Provides Information Emotions Linger When Memories Fade People With Amnesia or Alzheimer’s Disease Still Recall Emotions, Researchers Say View Source April 12, 2010 Provides Information Enabling Alzheimer's Disease patients and families to cope Providing people with early-stage Alzheimer's Disease with rehabilitation directed towards helping them with everyday activities is an effective means of enabling them and their families to manage the effects of the condition, research at Bangor University has shown. View Source August 11, 2010 Provides Information Exercise may be best way to fight Alzheimer's Advances in detection show need for better drugs to prevent disease, scientists say View Source July 12, 2010 Provides Information Experts look to music as way to uncover past buried by dementia One had to look closely, but the white sneaker definitely tapped the floor. Slightly, softly, steadily. Like a heartbeat. View Source June 23, 2010 Provides Information Extra education slows down dementia Delaying onset of symptoms could dramatically cut economic costs of the disease View Source July 26, 2010 Provides Information F Family caregiving stress filled and isolating Family members who provide care to relatives with dementia, but do not have formal training, frequently experience overwhelming stress that sometimes leads to breakdowns or depression, according to Penn State and Benjamin Rose Institute researchers. View Source April 22, 2010 Provides Information FDA approves larger dose of Pfizer's Aricept Drugmakers Eisai Inc. and Pfizer Inc. said on Saturday that government regulators have given them permission to make a larger dose of its Alzheimer's disease drug Aricept for patients who have already been taking the smaller dose. View Source July 25, 2010 Provides Information Fruit Flies and Test Tubes Open New Window on Alzheimer's Disease A team of scientists from Cambridge and Sweden have discovered a molecule that can prevent a toxic protein involved Alzheimer's disease from building up in the brain. They found that in test tube studies the molecule not only prevents the protein from forming clumps but can also reverse this process. Then, using fruit flies with Alzheimer's disease, they showed that the same molecule effectively "cures" the insects of the disease. View Source March 16, 2010 Provides Information Food Combination Associated With Reduced Alzheimer's Disease Risk Identified in New Study Individuals whose diet includes more salad dressing, nuts, fish, poultry and certain fruits and vegetables and fewer high-fat dairy products, red meats, organ meats and butter appear less likely to develop Alzheimer's disease, according to a report posted online that will appear in the June print issue of Archives of Neurology, one of the JAMA/Archives journals. View Source April 13, 2010 Provides Information Frontier research produces 3D neurological probe European scientists have created a pioneering three-dimensional (3D) brain probing system that may provide new leads for understanding schizophrenia, Alzheimer’s disease and other serious brain conditions. Created under the NEUROPROBES ('Development of multifunctional microprobe arrays for cerebral applications') project, which received almost EUR 10 million under the 'Information society technologies' (IST) Thematic area of the EU's Sixth Framework Programme (FP6), the neurological breakthrough has already generated considerable interest and demand worldwide. View Source May 28, 2010 Provides Information G Gene linked to aging also linked to Alzheimer's MIT biologists report that they have discovered the first link between the amyloid plaques that form in the brains of Alzheimer's patients and a gene previously implicated in the aging process, SIRT1. View Source July 22, 2010 Provides Information Gene Linked to Alzheimer's Disease Plays Key Role in Cell Survival Presenilin 1 Gene Enables Cell to Digest Toxic Proteins; Mutations Disrupt Crucial Function View Source June 10, 2010 Provides Information Gene makes people fat, raises Alzheimer's risk 1 in 3 have gene but low-fat diet, excercise can help, study finds View Source April 19, 2010 Provides Information Genetic Variations Associated With Alzheimer's Disease, but Do Not Help Predict Risk Although genome-wide analysis identified two genetic variations associated with Alzheimer disease (AD), these variations did not improve the ability to predict the risk of AD, according to a study in the May 12 issue of JAMA. View Source May 12, 2010 Provides Information Gently unfolding proteins to watch them refold How does a protein chain fold into the same 3-D shape each time and not something disfunctional or dangerous? A new study shows that the first fold is critical. The finding by Susan Marqusee and Carlos Bustamante could help to understand the role of misfolded proteins in Alzheimer's Disease. View Source June 7, 2010 Provides Information Gum Inflammation Linked to Alzheimer's Disease NYU dental researchers have found the first long-term evidence that periodontal (gum) disease may increase the risk of cognitive dysfunction associated with Alzheimer's disease in healthy individuals as well as in those who already are cognitively impaired. View Source August 4, 2010 Provides Information H Hallmark Alzheimer's disease changes found in retinas of humans and imaged in live animals The nerve cell-damaging plaque that builds up in the brain with Alzheimer's disease also builds up in the retinas of the eyes - and it shows up there earlier, leading to the prospect that noninvasive optical imaging of the eyes could lead to earlier diagnosis, intervention and monitoring of the disease, according to new research. View Source June 24, 2010 Provides Information Having greater purpose in life associated with a reduced risk of Alzheimer's disease Individuals who report having greater purpose in their lives appear less likely to develop Alzheimer's disease or its precursor, mild cognitive impairment, according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals. View Source March 1, 2010 Provides Information High Blood Levels of Vitamin E Reduces Risk of Alzheimer's, Swedish Study Finds High levels of several vitamin E components in the blood are associated with a decreased risk for Alzheimer's disease (AD) in advanced age, suggesting that vitamin E may help prevent cognitive deterioration in elderly people. This is the conclusion reached in a Swedish study published in the July 2010 issue of the Journal of Alzheimer's Disease. View Source July 7, 2010 Provides Information Home-based intervention may provide some benefit to patients with dementia and their caregivers An intervention that targeted modifiable stressors in the home of patients with dementia resulted in better outcomes for the patients and their caregivers at 4 months, but not at 9 months, although the caregivers perceived greater benefits, according to a study in the September 1 issue of JAMA. View Source August 31, 2010 Provides Information How Mutations in Presenilin Gene Cause Early Onset Alzheimer's Disease Researchers have discovered how mutations in the presenilin 1 gene cause early-onset Alzheimer's disease (AD). The finding, reported online in the journal Cell, opens the door to developing novel treatments for this form of the mind-robbing disease and for the more common, late-onset form that develops later in life and affects millions of people worldwide. View Source June 11, 2010 Provides Information How the Demons of Dementia Possess and Damage Brain Cells A study from EPFL's Laboratory of Neuroenergetics and Cellular Dynamics in Lausanne Switzerland, published March 3 in the Journal of Neuroscience, may lead to new forms of treatment following a better understanding of how amyloid-beta found in cerebral plaques, typically present in the brain of Alzheimer's patients, may lead to neurodegeneration. Researchers in Lausanne have studied how the functions of certain cells called astrocytes-which normally protect, repair, and transfer energy to neurons-are impaired when "possessed" by aggregated amyloid-beta. View Source March 4, 2010 Provides Information I Individuals with Alzheimer's disease may lose muscle mass the weight of an individual's bones, muscles and organs without body fat—appears to decline among patients with Alzheimer's disease, according to a report in the April issue of Archives of Neurology. These decreases may be associated with declines in brain volume and function. View Source April 12, 2010 Provides Information Independent Panel Finds Insufficient Evidence to Support Preventive Measures for Alzheimer's Disease Many preventive measures for cognitive decline and for preventing Alzheimer's disease—mental stimulation, exercise, and a variety of dietary supplements—have been studied over the years. However, an independent panel convened this week by the National Institutes of Health determined that the value of these strategies for delaying the onset and/or reducing the severity of decline or disease hasn't been demonstrated in rigorous studies. View Source April 28, 2010 Provides Information Insulin Nasal Spray May Help Treat Alzheimer's Study Shows Insulin Spray Linked With Improvement in Memory of Alzheimer's Patients View Source July 14, 2010 Provides Information Insulin resistance, type 2 diabetes linked to plaques associated with Alzheimer's disease People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated with Alzheimer's disease, according to new research published in the August 25, 2010, issue of Neurology, the medical journal of the American Academy of Neurology. View Source August 25, 2010 Provides Information Intellect Neurosciences locks database of OXIGON Phase 1b clinical trial for Alzheimer's disease Intellect Neurosciences, Inc. a biopharmaceutical company with an internal preclinical and clinical-stage pipeline and licenses with major pharmaceutical companies covering products in late-stage clinical trials, announced that it has locked the database of the Company's Phase 1b clinical trial for its lead Alzheimer's candidate, OXIGON™ (OX1). View Source August 18, 2010 Provides Information Intellect Neurosciences receives Notice of Allowance for new OXIGON patent in Canada Intellect Neurosciences, Inc announced that it has received a Notice of Allowance from the Canadian Patent and Trademark Office for a new patent related to OX1 (OXIGON™), the Company's clinical-stage drug candidate that has disease-modifying potential for Alzheimer's and other neurodegenerative disorders. View Source August 9, 2010 Provides Information L Larger Head Size May Help Alzheimer's Patients Study Shows a Large Head May Boost Thinking Skills for People With Alzheimer's Disease View Source July 12, 2010 Provides Information Low Blood Flow Ages Brain Faster When Heart Pumps Less Blood, Brain May Be at Risk for Dementia View Source August 2, 2010 Provides Information M Major breakthrough in Alzheimer research: Looking for Alzheimer's causes at cellular level Researchers from the University of Sydney's Alzheimer's and Parkinson's Disease Laboratory have achieved a major breakthrough by finding the causes of Alzheimer's disease at a cellular level and thereby identifying a potential therapy as a result. View Source July 23, 2010 Provides Information Major depression more than doubles risk of dementia among adults with diabetes Adults who have both diabetes and major depression are more than twice as likely to develop dementia, compared to adults with diabetes only, according to a study published in the recent Journal of General Internal Medicine. View Source March 5, 2010 Provides Information Maria Shriver joins Alzheimer's Association to release The Shriver Report Maria Shriver, in Partnership with the Alzheimer's Association, Takes a Groundbreaking Look into the Epidemic's Effect on Women as Caregivers, Advocates, and People Living With Alzheimer's. View Source August 24, 2010 Provides Information Mechanism links abnormal blood clots with Alzheimer's disease New research suggests that abnormalities in the process of blood clot formation may contribute to the pathogenesis of Alzheimer's disease (AD). The study, published by Cell Press in the June 10 issue of the journal Neuron, advances our understanding of the link between vascular pathology and AD and proposes a new therapeutic strategy aimed at slowing cognitive decline. View Source June 9, 2010 Provides Information Media memories help people with dementia to unlock the past People with dementia are to be given help to unlock their memories, thanks to academic research by teams at the Universities of St Andrews and Dundee. View Source March 25, 2010 Provides Information Memory May Decline Rapidly Even in Stage Before Alzheimer's Disease Memory and thinking skills may decline rapidly for people who have mild cognitive impairment, which is the stage before Alzheimer's disease when people have mild memory problems but no dementia symptoms, and even more rapidly when dementia begins, which is when Alzheimer's disease is usually diagnosed. View Source March 23, 2010 Provides Information Memory problems not the only predictor of later mild cognitive impairment Mild cognitive impairment is often seen as a transition stage between the cognitive decline of normal aging and the more serious problems of Alzheimer's disease. But what leads to mild cognitive impairment? View Source June 28, 2010 Provides Information Mental problems in an old person do not always mean Alzheimer's disease The case of an elderly woman who had mental problems associated with Alzheimer's disease, but turned out to have treatable limbic encephalitis, is detailed in a Case Report in this week's edition of The Lancet. The case is important because, with rapidly increasing numbers of elderly people worldwide, it is important that when they present with such symptoms they are correctly diagnosed and not just assumed to have Alzheimer's disease (or typical dementia). The Case Report is written by Dr Nathalie Costedoat-Chalumeau, Centre Hospitalier Universitaire Pitie-Salpetriere, Paris, France, and colleagues. View Source August 19, 2010 Provides Information Mild cognitive impairment study offers insight on Alzheimer's People who are not aware they are developing mild memory problems as they age may develop Alzheimer's disease at a faster rate than those who do notice their memory is slipping. View Source April 21, 2010 Provides Information More Choline for Pregnant, Nursing Women Could Reduce Down Syndrome Dysfunction, Guard Against Dementia More choline during pregnancy and nursing could provide lasting cognitive and emotional benefits to individuals with Down syndrome and protect against neurodegenerative conditions such as Alzheimer's disease, suggests a new Cornell study of mice. View Source June 4, 2010 Provides Information Moving My Mom in With Me Here are the challenges I'm facing as I prepare to move a parent with dementia into my house. View Source May 27, 2010 Provides Information Music aids Alzheimer's patients in remembering new information Researchers from Boston University School of Medicine (BUSM) have shown that patients with Alzheimer's disease (AD) are better able to remember new verbal information when it is provided in the context of music even when compared to healthy, older adults. The findings, which currently appear on-line in Neuropsychologia, offer possible applications in treating and caring for patients with AD. View Source May 12, 2010 Provides Information Mutant gum disease bacteria provide clue to treatment for Alzheimer's A defective, mutant strain of the bacterium that causes gum disease could provide a clue to potential treatments for Alzheimer's, Parkinson's and a number of other diseases. Researchers from the University of Florida College of Dentistry report their findings today at the 110th General Meeting of the American Society for Microbiology in San Diego. View Source May 25, 2010 Provides Information N Neurodegeneration 'clumping proteins' common in aging process Many proteins that form insoluble clumps in the brains of people with Alzheimer's and other neurodegenerative diseases are also found in healthy individuals and clump together as a normal part of aging. According to a surprising new finding by researchers at the University of California, San Francisco, the discovery in the C. elegans roundworm refutes a widespread belief that these clumps are unique to degenerative disease and created by proteins specific to those diseases. The team also found that gene manipulations that extend the lifespan of C. elegans prevent the formation of these insoluble aggregates. View Source August 10, 2010 Provides Information Neuroimaging study describes Alzheimer's disease-like changes in elderly people without the disease The emergence of multiple new brain imaging technologies and the combined application of these new approaches is helping to create new insights into aging and Alzheimer's disease. One of the hallmarks of Alzheimer's disease is the deposition of amyloid beta protein in clumps or "plaques" within the brain. These plaques can be measured in humans with PET scans that use a chemical marker or radiotracer called 11C-PIB. View Source March 15, 2010 Provides Information New Alzheimer vaccine to be tested in Europe A new vaccine against Alzheimer's, developed by the Austrian biotechnology firm Affiris, will soon be tested in six European countries, the company announced Friday. View Source April 23, 2010 Provides Information New Alzheimer's test offers better opportunities for early detection Early detection is key to more effective treatment for Alzheimer's disease and other forms of cognitive impairment, and new research shows that a test developed at the University of Tennessee is more than 95 percent effective in detecting cognitive abnormalities associated with these diseases. View Source March 11, 2010 Provides Information New approach to Alzheimer's therapy Researchers from the German Centre for Neurodegenerative Diseases and the Ludwig-Maximilians-Universitat in Munich have shown that the ADAM10 protein can inhibit the formation of beta-amyloid, which is responsible for Alzheimer's disease. ADAM10 acts like a pair of molecular scissors to cut the protein from which beta-amyloid is formed, effectively preventing the formation of beta-amyloid. This makes ADAM10 a key molecule in Alzheimer's therapy. View Source July 30, 2010 Provides Information New book offers formula for Alzheimer's disease management and prevention With the aging of nearly 80 million baby boomers, Alzheimer's disease is an impending epidemic that requires a new approach to prevention as well as management of the disease, according to a UC Santa Barbara professor who has co-authored a new book on the topic. View Source May 25, 2010 Provides Information New Brain-Protecting Compound Works in Rats; Could Make Alzheimer's a Distant Memory Researchers at Texas Southwestern Medical Center have discovered a compound that could potentially render Alzheimer's a thing of the past. After testing 1,000 different molecules on the memory hubs of rats suffering from memory loss, scientists there have come up with a compound that protects memory-forming cells in the hippocampus, which could lead to promising treatments for Alzheimer's and other memory affecting disorders View Source July 9, 2010 Provides Information New Criteria for Diagnosing Alzheimer's Coming Earlier Diagnosis Needed as New Drugs Come Down the Pike View Source August 4, 2010 Provides Information New ethical guidelines needed for dementia research How do we handle the ethical dilemmas of research on adults who can't give their informed consent? In a recent article in the journal Bioethics, ethicist Stefan Eriksson proposes a new approach to the dilemma of including dementia patients and others with limited decision making capabilities in research. View Source March 29, 2010 Provides Information New evidence caffeine may slow Alzheimer's disease and other dementias, restore cognitive function Although caffeine is the most widely consumed psychoactive drug worldwide, its potential beneficial effect for maintenance of proper brain functioning has only recently begun to be adequately appreciated. Substantial evidence from epidemiological studies and fundamental research in animal models suggests that caffeine may be protective against the cognitive decline seen in dementia and Alzheimer's disease (AD). A special supplement to the Journal of Alzheimer's Disease, "Therapeutic Opportunities for Caffeine in Alzheimer's Disease and Other Neurodegenerative Diseases," sheds new light on this topic and presents key findings. View Source May 17, 2010 Provides Information New fMRI Approach Pinpoints Early Brain Disease University of Oxford researchers have been using a technique called Resting-state fMRI to detect similarities among people with a common brain condition. In a paper published in the Proceedings of the National Academy of Sciences, the scientists had people undergo fMRI scanning while doing nothing at all. View Source March 1, 2010 Provides Information New gene associated with increased risk of Alzheimer's disease Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease, the most common type of Alzheimer's disease. The research will be presented as part of the late-breaking science program at the American Academy of Neurology's 62nd Annual Meeting in Toronto, April 10 - 17, 2010. The gene, abbreviated MTHFD1L, is located on chromosome six. View Source April 14, 2010 Provides Information New method for producing proteins critical to medical research Scientists at the University of Delaware have developed a new method for producing proteins critical to research on cancer, Alzheimer's, and other diseases. View Source April 1, 2010 Provides Information New method to study key targets in Alzheimer's disease and prostate cancer When designing a drug against a disease, chemists often used detailed plans of the proteins affected and against which the drugs must act. However, about a third of the proteins of our bodies have not yet been "photographed" because they generally vary in form, are in constant movements and have very little structure. View Source April 8, 2010 Provides Information New model suggests feared side effect of Alzheimer's drugs is unlikely The first trial of a new model for testing Alzheimer's treatments has reassured researchers that a promising class of drugs does not exacerbate the disease if treatment is interrupted. View Source June 17, 2010 Provides Information New molecular imaging agent may help visualize early stages of Alzheimer's disease A multinational clinical trial revealed at SNM's 57th Annual Meeting presents a novel imaging agent that could be the next major breakthrough for the early detection of Alzheimer's disease -- a slow but fatal neurodegenerative disease. The new agent is used in conjunction with a molecular imaging technique called positron emission tomography (PET) and works by binding to beta-amyloid, a naturally-occurring protein that builds up in the brain and is thought to be a precursor to Alzheimer's. View Source June 7, 2010 Provides Information New pathway to Parkinson's and Alzheimer's diseases Although their genetic underpinnings differ, Alzheimer's disease, Parkinson's disease and Huntington's disease are all characterized by the untimely death of brain cells. What triggers cell death in the brain? According to a new study published by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) in the July 30 issue of Molecular Cell, the answer in some cases is the untimely transfer of a gaseous molecule (known as nitric oxide, or NO) from one protein to another. View Source July 29, 2010 Provides Information New perspective in ion channel indicates treatment potential Scientists researching a toxin extracted from the venom of the honey bee have used this to inform the design of new treatments to alleviate the symptoms of conditions such as muscular dystrophy, depression and dementia. View Source July 9, 2010 Provides Information New Study Characterizes Cognitive and Anatomic Differences in Alzheimer's Disease Gene Carriers In the most comprehensive study to date, neurologists have clearly identified significant differences in the ways that Alzheimer's disease affects patients with and without the apolipoprotein E e4 gene, a known genetic risk factor for the neurodegenerative disease, using a combination of cognitive and neuroanatomic measures. The study found that this gene influences the way the disease manifests, even at its mildest clinical stages. View Source May 19, 2010 Provides Information New study identifies best tests for predicting Alzheimer's disease New research has identified the memory and brain scan tests that appear to predict best whether a person with cognitive problems might develop Alzheimer's disease. The research is published in the June 30, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology. View Source June 30, 2010 Provides Information New test can help diagnose Alzheimer's Spinal fluid proteins show promise in predicting who will develop the disease View Source August 9, 2010 Provides Information New test takes guesswork out of diagnosing early-stage Alzheimer's disease A new test developed by Japanese scientists may revolutionize how and when physicians diagnose Alzheimer's disease. According to a research report published online in The FASEB Journal, the new test measures proteins in the spinal fluid known to be one of the main causes of brain degeneration and memory impairment in Alzheimer's patients: high molecular weight A-Beta oligomers. This tool, once fully implemented, would allow physicians to diagnose and treat Alzheimer's disease in its early stages, a time when diagnosing the disease is very difficult. View Source March 25, 2010 Provides Information New Ways to Diagnose and Treat Alzheimer's, Findings Suggest A team of researchers at UMass Lowell has found a new mechanism by which a key protein associated with Alzheimer's disease can spread within the human brain. View Source March 1, 2010 Provides Information NIH-Supported Study Looks for Earliest Changes in the Brain That May Lead to Alzheimer's Disease Volunteers are being sought for a clinical study examining the subtle changes that may take place in the brains of older people many years before overt symptoms of Alzheimer’s disease appear. Researchers are looking for people with the very earliest complaints of memory problems that affect their daily activities. The study will follow participants over time, using imaging techniques developed to advance research into changes taking place in the structure and function of the living brain, as well as biomarker measures found in blood and cerebrospinal fluid. View Source June 2, 2010 Provides Information No Proof Healthy Lifestyle Prevents Alzheimer’s Despite Findings, People Shouldn't Toss Healthy Habits Like Physical and Mental Exercise, Researchers Say View Source June 14, 2010 Provides Information Novel radiotracer shines new light on the brains of Alzheimer's disease patients A trial of a novel radioactive compound readily and safely distinguished the brains of Alzheimer's disease patients from healthy volunteers on brain scans and opens the doors to making such imaging available beyond facilities that can manufacture their own radioactive compounds. The results, reported by a Johns Hopkins team in the June Journal of Nuclear Medicine, could lead to better ways to distinguish Alzheimer's from other types of dementia, track disease progression and develop new therapeutics to fight the memory-ravaging disease. View Source June 24, 2010 Provides Information O O2h signs agreement to provide Senexis with chemistry services to support patent filing Executives from Senexis Limited (Cambridge,UK) signed an agreement with O2h (Ahmedabad, India) under which O2h will provide Senexis with chemistry services to support a patent filing on a novel chemical series that have shown potential in pre-clinical models, as disease modifying treatments for Alzheimer's Disease. View Source June 14, 2010 Provides Information Off-the-shelf genetics tests to hit US pharmacies Want to find out what diseases await you in the future, your chances of developing Alzheimer's? Or whether you will pass something on to your child? Then a trip to the pharmacy may reveal all. View Source May 11, 2010 Provides Information One-in-six elderly dementia patients receiving anti-psychotic drugs More than one in six elderly patients across Scotland with dementia are being prescribed anti-psychotic drugs known to be of limited benefit and causing significant harm, a major study carried out at the University of Dundee has confirmed. View Source July 23, 2010 Provides Information Over-abundant protein prompts neurodegenerative cascade In diverse neurodegenerative diseases ranging from Parkinson's to Alzheimer's, researchers have long noted accumulations of a little-understood neuronal protein called a-synuclein. Pathological and genetic evidence strongly suggested that excessive a-synuclein played a role in the evolution of these diseases, but it was unclear how too much a-synuclein culminated in synaptic damage and neurodegeneration. View Source June 15, 2010 Provides Information P People with Alzheimer's disease experience higher rate of cognitive decline: New study People with Alzheimer's disease experience a rate of cognitive decline four times greater than those with no cognitive impairment according to a new study by researchers at Rush University Medical Center in Chicago. View Source March 23, 2010 Provides Information Pivotal study finds link between PTSD and dementia Results of a study reported in the September issue of the Journal of the American Geriatrics Society suggest that Veterans with post-traumatic stress disorder (PTSD) have a greater risk for dementia than Veterans without PTSD, even those who suffered traumatic injuries during combat. View Source September 2, 2010 Provides Information Plasma beta-amyloid levels associated with cognitive decline Protein fragments associated with Alzheimer's disease when they accumulate in the brain—appear to be associated with faster cognitive decline even in those who do not develop dementia, according to a report posted online today that will appear in the December print issue of Archives of Neurology, one of the JAMA/Archives journals. View Source August 9, 2010 Provides Information Plasma protein appears to be associated with development and severity of Alzheimer's disease Higher concentrations of clusterin, a protein in the blood plasma, appears to be associated with the development, severity and progression of Alzheimer's disease, according to a report in the June issue of Archives of General Psychiatry. View Source July 5, 2010 Provides Information Post-traumatic stress disorder associated with dementia among older veterans Older veterans with post-traumatic stress disorder (PTSD) appear more likely to develop dementia over a seven-year period than those without PTSD, according to a report in the June issue of Archives of General Psychiatry. View Source June 7, 2010 Provides Information Predicting the Progression of Alzheimer's An assessment has been developed which reliably predicts future performance in cognition and activities of daily living for patients with Alzheimer's disease. Researchers writing in BioMed Central's open access journal Alzheimer's Research & Therapy followed 597 patients over 15 years to identify factors associated with slow, intermediate and rapid progression. View Source March 4, 2010 Provides Information Predisposing factors for conversion of mild cognitive impairment to AD identified Mild cognitive impairment (MCI) is often considered an early symptom of Alzheimer's disease (AD). An analysis of genetic risk factors predisposing to MCI is critical for accessing individual predisposition and reliably evaluating the effectiveness of early treatment. View Source March 1, 2010 Provides Information Problematic blood clotting contributes to Alzheimer’s disease (w/ Video) Alzheimer's disease isn't just about twisted brain cells. It's also about the blood vessels that feed those neurons. New research at Rockefeller University has shown how the most common element of the plaque deposits found outside the brain cells of Alzheimer’s patients interacts with a blood clotting agent and causes clots to form faster and become harder to break down. The scientists suggest new drugs that would target this association could potentially treat what is increasingly recognized as a crucial element of the disease, the vascular component. View Source June 16, 2010 Provides Information Promising Alzheimer's med shown to worsen symptoms Development halted after trials show semagacestat impairs cognition View Source August 17, 2010 Provides Information Promising New Drug Target for Alzheimer's Disease Researchers at the University of Illinois have identified a potential drug target for the treatment of Alzheimer's disease: a receptor that is embedded in the membrane of neurons and other cells. View Source April 20, 2010 Provides Information Protein regulates enzyme linked to Alzheimer's disease Researchers at Tufts University School of Medicine have zeroed in on a protein that may play a role in the progression of Alzheimer's disease. The team found that increasing levels of the protein (called GGA3) prevented the accumulation of an enzyme linked to Alzheimer's. The strategy may lead to new treatments for the neurodegenerative disease. The findings were published online May 18 in the Journal of Biological Chemistry. View Source May 25, 2010 Provides Information Proteins linked to longevity also linked to Alzheimer's Over the past 20 years, scientists have learned that proteins called sirtuins play a vital role in longevity and stress response in organisms as diverse as humans, yeast and mice. A new paper from MIT biologists now reveals a surprising additional role for sirtuins: They appear to suppress the production of amyloid beta proteins, which form plaques in the brains of Alzheimer’s patients. View Source July 27, 2010 Provides Information Proteins Linked With Alzheimer's, Other Neurodegenerative Diseases Found to Clump in Normal Aging In neurodegenerative diseases, clumps of insoluble proteins appear in patients' brains. These aggregates contain proteins that are unique to each disease, such as amyloid beta in Alzheimer's disease, but they are intertwined with small amounts of many other insoluble proteins that are normally present in a soluble form in healthy young individuals. For years, these other proteins were thought to be accidental inclusions in the aggregates, much as a sea turtle might be caught in a net of fish. View Source August 11, 2010 Provides Information Putting the squeeze on Alzheimer's (w/ Video) Brain cells exposed to a form of the amyloid beta protein, the molecule linked to Alzheimer's disease, become stiffer and bend less under pressure, researchers at UC Davis have found. The results reveal one mechanism by which the amyloid protein damages the brain, a finding that could lead to new ways to screen drugs for Alzheimer's and similar diseases. View Source August 20, 2010 Provides Information Q QR Pharma to present clinical data from mechanism of action study in MCI patients at ICAD 2010 QR Pharma, Inc., a developer of novel drugs to treat Alzheimer's disease (AD), announced today that it has been accepted to present a poster on clinical data from its recent mechanism of action study in mild cognitive impaired (MCI) patients at the International Congress on Alzheimer's Disease (ICAD 2010). View Source July 2, 2010 Provides Information QR Pharma to present positive clinical data from mechanism of action study in MCI at ICAD 2010 QR Pharma, Inc., a developer of novel drugs to treat Alzheimer's disease (AD), is presenting a poster today on positive clinical data from its recent mechanism of action study in mild cognitive impaired (MCI) patients at the International Congress on Alzheimer's Disease (ICAD 2010). View Source July 15, 2010 Provides Information R Reducing Alzheimer's-related protein in young brains improves learning in Down syndrome animal model Reducing a protein called beta-amyloid in young mice with a condition resembling Down syndrome improves their ability to learn, researchers at UT Southwestern Medical Center have found. View Source June 3, 2010 Provides Information Regular and long enough intake of EGb 761 protects against Alzheimer's disease: GuidAge study For the very first time, a medicine has been shown to protect against the development of Alzheimer's disease. French scientists were able to demonstrate that taking 240 mg of Ginkgo extract EGb 761® per day regularly over a period of at least 4 years can cut the risk of developing Alzheimer's disease by nearly 50%. View Source June 23, 2010 Provides Information Research confirms benefits of PET scan in early detection of Alzheimer's disease Westside Medical Associates of Los Angeles and Westside Medical Imaging (WMI) of Beverly Hills announce the benefit of early positron emission tomography (PET) scanning to identify Alzheimer's in its early more treatable phase. View Source March 17, 2010 Provides Information Research offers clues to Alzheimer's disease An organic compound found in red wine - resveratrol - has the ability to neutralize the toxic effects of proteins linked to Alzheimer's disease, according to research led by Rensselaer Professor Peter M. Tessier. The findings, published in the May 28 edition of the Journal of Biological Chemistry, are a step toward understanding the large-scale death of brain cells seen in certain neurodegenerative diseases. View Source June 22, 2010 Provides Information Researcher developing novel therapy for Alzheimer's disease A University of Oklahoma researcher is developing a novel therapy for Alzheimer's disease using "biopharmaceutical proteases" to attack the toxic plaque that builds up in the brain of an Alzheimer's patient -- an approach that he predicts will be lower in cost and higher in effectiveness than current therapies. View Source July 8, 2010 Provides Information Researchers commence Phase 2 research study to test CERE-110 for AD Researchers at Banner Sun Health Research Institute are about to start the first Phase 2 research study to test a gene transfer agent for Alzheimer's disease (AD). AD is a degenerative and ultimately fatal disorder affecting as many as five million Americans and that number is expected to soar to more than 11 million by 2040. For the first time in AD research, scientists are about to test the efficacy of a gene transfer therapy called CERE-110. View Source April 7, 2010 Provides Information Researchers design self-test for memory disorders A self-administered test to screen for early dementia could help speed the diagnosis and subsequent treatment of memory disorders, including Alzheimer's disease. It could also provide health care providers and caregivers an earlier indication of life-changing events that could lie ahead. View Source March 31, 2010 Provides Information Researchers discover possible way to predict Alzheimer's Two new studies, involving a newly identified gene, show that Alzheimer's disease could be diagnosed as much as 20 years before symptoms develop. View Source July 14, 2010 Provides Information Researchers discover protein that stimulates production of beta-amyloid Researchers at the Fisher Center for Alzheimer's Disease Research laboratory today published "Gamma-secretase Activating Protein is a Therapeutic Target for Alzheimer's Disease" in Nature online. Drs. Gen He (lead author) and Paul Greengard have discovered a protein that stimulates the production of beta-amyloid, and therefore represents a major new advance in Alzheimer's disease research. View Source September 2, 2010 Provides Information Researchers discover weak link in Alzheimer's drug candidates Some current therapies being investigated for Alzheimer's disease may cause further neural degeneration and cell death, according to a breakthrough discovery by UC San Diego researchers. View Source April 1, 2010 Provides Information Researchers Find Clues for Early Alzheimer's Experts Discover How a Genetic Mutation Causes Early-Onset Alzheimer's View Source June 10, 2010 Provides Information Researchers look for new ways of targeting Alzheimer's disease The Alzheimer's Association released a report on Wednesday, May 19, predicting that the cost of Alzheimer's disease over the next 40 years would reach $20 trillion if newer treatments are not on the horizon. View Source May 24, 2010 Provides Information Researchers participate in Alzheimer's Breakthrough Ride to urge Congress make the disease a national priority This summer, more than 55 researchers participating in the Alzheimer's Breakthrough Ride(SM) are cycling relay-style across the country, collecting petition signatures asking Congress to make Alzheimer's disease a national priority. The public response to the petition has been so overwhelming that as the Alzheimer's Breakthrough Riders hit the halfway point in their 67-day route from San Francisco to Washington, D.C. on August 18, they are already more than 80% of the way to their goal of 50,000 signatures. View Source August 18, 2010 Provides Information Researchers uncover biochemical pathway by which harmful molecule may raise Alzheimer's risk A molecule implicated in Alzheimer's disease interferes with brain cells by making them unable to "recycle" the surface receptors that respond to incoming signals, researchers at UT Southwestern Medical Center have found. View Source June 14, 2010 Provides Information Resveratrol found in red wine neutralizes toxicity of proteins related to Alzheimer's disease: Research Compound found in red wine neutralizes toxicity of proteins related to Alzheimer's View Source June 23, 2010 Provides Information Rheumatoid arthritis signaling protein reverses Alzheimer's disease in mouse model A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer's disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a new study by the University of South Florida reports. Researchers found that the protein, GM-CSF, likely stimulates the body's natural scavenger cells to attack and remove Alzheimer's amyloid deposits in the brain. View Source August 23, 2010 Provides Information S Scientists discover characteristic amyloid plaques in retinas from Alzheimer's disease patients Scientists discovered characteristic amyloid plaques in retinas from Alzheimer's disease patients and used a noninvasive optical imaging technique to detect retinal plaques in live laboratory mice, suggesting the possibility of early noninvasive diagnosis View Source June 25, 2010 Provides Information Scientists discover how neuroglobin protects against Alzheimer's A team of scientists at the University of California, Davis and the University of Auckland has discovered that neuroglobin may protect against Alzheimer's disease by preventing brain neurons from dying in response to natural stress. The team published the results of their study in the April, 2010 issue of Apoptosis. View Source August 2, 2010 Provides Information Scientists Find Blood Protein Link to Alzheimer's High levels of a blood protein called clusterin are linked to the development of Alzheimer's disease, scientists said on Monday — a finding which could pave the way for doctors to detect the disease before it takes hold. View Source July 6, 2010 Provides Information Scientists Find New Form of Prion Disease that Damages Brain Arteries Study in Mice May Offer Clues for Treating Alzheimer's Disease View Source March 5, 2010 Provides Information Scientists find new, inexpensive way to predict Alzheimer's disease Your brain's capacity for information is a reliable predictor of Alzheimer's disease and can be cheaply and easily tested, according to scientists. View Source April 5, 2010 Provides Information Scientists gather to discuss latest advances in Alzheimer's disease at AAICAD 2010 This week, nearly 4,000 scientists from around the world gathered to report and discuss the latest advances in research on treatments, risk factors, and diagnosis for the health epidemic of the 21st century – Alzheimer's disease – at the Alzheimer's Association's 2010 International Conference on Alzheimer's Disease (AAICAD 2010) in Honolulu. View Source July 15, 2010 Provides Information Scientists identify protein that spurs formation of Alzheimer's plaques In Alzheimer's disease, the problem is beta-amyloid, a protein that accumulates in the brain and causes nerve cells to weaken and die. Drugs designed to eliminate plaques made of beta-amyloid have a fatal problem: they need to enter the brain and remove the plaques without attacking healthy brain cells. New research from the laboratory of Nobel Prize winner Paul Greengard, however, suggests that treatments modeled on the blockbuster cancer drug Gleevec could be the solution. View Source September 1, 2010 Provides Information Scientists reverse Alzheimer's-like memory loss in fruit flies By blocking the cellular signaling activity of a protein, a team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has prevented memory loss in fruit flies caused by brain plaques similar to those thought to cause Alzheimer's disease in humans. The study also resolves a long-standing controversy about the role of this protein, PI3 kinase, which was previously thought to have a protective function against the disease. View Source March 29, 2010 Provides Information Sea Squirt Offers Hope for Alzheimer's Sufferers Alzheimer's disease affects an estimated 27 million people worldwide. It is the most common form of age-related dementia, possibly the most feared disease of old age. There is no cure, and the available drugs only help to relieve symptoms without slowing progression of the disease. One of the characteristic changes in the brains of Alzheimer's patients is the accumulation of plaques and tangles; currently, the best hope for curing or at least slowing the disease lies in developing drugs that target this buildup. Some drugs are already in clinical trials, but there is still a pressing need for more research, and for more and better drugs directed against both known and novel targets. View Source March 3, 2010 Provides Information Sleep disorder may signal dementia, Parkinson's disease up to 50 years early A new study shows that a sleep disorder may be a sign of dementia or Parkinson's disease up to 50 years before the disorders are diagnosed. The research is published in the July 28, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology. View Source July 28, 2010 Provides Information Sorting when early memory loss signals big threat Doctors can't tell if Leif Utoft Bollesen's mild memory loss will remain an annoyance or worsen, but experimental checks of the Minnesota man's aging brain may offer clues. View Source August 9, 2010 Provides Information Southampton scientists reveal crucial dementia vaccine findings Scientists from the University of Southampton presented findings this week at the world’s biggest dementia research conference on a vaccine trial for dementia. The study, funded by the Alzheimer’s Research Trust, has revealed important new evidence about the hallmark protein build-up that takes place during Alzheimer’s. View Source July 15, 2010 Provides Information Special care plan does not slow decline in patients with Alzheimer's A special dementia care plan, involving regular assessments of patients with Alzheimer's disease in specialist memory clinics, does not slow functional decline compared with usual care, finds a study published in the British Medical Journal today. View Source June 4, 2010 Provides Information Spinal Fluid Test May Diagnose Alzheimer's Study Shows Proteins Could Help Identify Cases of Alzheimer's Disease View Source August 9, 2010 Provides Information Spouses of dementia sufferers at higher risk of developing dementia Older married adults whose spouse has dementia are at significantly higher risk for developing dementia themselves, compared to similar older married adults whose spouse never develops dementia. This is the key finding of a study published today in the Journal of the American Geriatrics Society. View Source May 5, 2010 Provides Information Spouses of dementia sufferers at higher risk of developing dementia Older married adults whose spouse has dementia are at significantly higher risk for developing dementia themselves, compared to similar older married adults whose spouse never develops dementia. This is the key finding of a study published today in the Journal of the American Geriatrics Society. View Source May 5, 2010 Provides Information Stimulating care homes can help people living with dementia New research by Kingston University has revealed how design can improve the quality of life for people with dementia. The University hopes the new study will form a blueprint for future building, lay-out and management of care homes. View Source April 9, 2010 Provides Information Stress in middle age could contribute to late-life dementia Psychological stress in middle age could lead to the development of dementia later in life, especially Alzheimer's disease, reveals research from the University of Gothenburg, Sweden. Based on data from a study which followed women for 35 years, this is the first research in Sweden to indicate a link between stress and dementia. View Source August 16, 2010 Provides Information Studies support association of physical activity, diet with maintaining cognitive ability, reducing dementia risk Evidence from three long-term, large-scale studies supports the association of physical activity and certain dietary elements (tea, vitamin D) with possibly maintaining cognitive ability and reducing dementia risk in older adults, according to new research presented today at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD 2010) in Honolulu, HI. View Source July 12, 2010 Provides Information Study: ChEI improves driving skills in patients with mild AD A promising study from Rhode Island Hospital demonstrated that cholinesterase inhibitors (ChEI), a type of medication often prescribed for Alzheimer's disease (AD), improved some cognitive skills in patients with mild AD - skills that are necessary for driving. Findings from the study showed that after being treated with a ChEI, AD patients improved in some computerized tests of executive function and visual attention, including a simulated driving task. View Source June 10, 2010 Provides Information Study evaluates association of genetic factors and brain imaging findings in Alzheimer's disease By investigating the association between genetic loci related to Alzheimer's disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer's disease and also may have identified new genetic risk factors for further study, according to a report in the June issue of Archives of Neurology. View Source June 14, 2010 Provides Information Study explains why Alzheimer's drug is both safe and effective Alzheimer's disease destroys brain cells and their connections (called synapses), causing memory loss and other cognitive problems that disrupt work, hobbies and daily life. Symptoms can be alleviated, in part, by the drug memantine (marketed in the United States as Namenda), which is currently FDA-approved to treat moderate-to-severe Alzheimer's disease and was, in part, developed by Stuart A. Lipton, M.D., Ph.D., Director of the Del E. Web Center for Neuroscience, Aging and Stem Cell Research at Sanford-Burnham Medical Research Institute (Sanford-Burnham). View Source August 18, 2010 Provides Information Study finds Alzheimer's disease link in eyes of children with Down syndrome A team of researchers has discovered that the protein that forms plaques in the brain in Alzheimer's disease also accumulates in the eyes of people with Down syndrome. The new findings in Down syndrome show that the toxic protein, known as amyloid-β, that causes Alzheimer's pathology in the brain also leads to distinctive cataracts in the eyes. View Source May 20, 2010 Provides Information Study Shows Games Could Help Stave Off Alzheimer's Research at East Carolina University has identified improvements to mental acuity among people ages 50 and up who play games. View Source May 26, 2010 Provides Information T Targeting the Blood-Brain Barrier May Delay Progression of Alzheimer's Disease Researchers may be one step closer to slowing the onset and progression of Alzheimer's disease. An animal study supported by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, shows that by targeting the blood-brain barrier, researchers are able to slow the accumulation of a protein associated with the progression of the illness. The blood-brain barrier separates the brain from circulating blood, and it protects the brain by removing toxic metabolites and proteins formed in the brain and preventing entry of toxic chemicals from the blood. View Source April 12, 2010 Provides Information U Uncovering early stages of Alzheimer's Disease A major Australian study has provided new insights into the loss of structure in regions of the brain and its potential association with Alzheimer's Disease. View Source March 26, 2010 Provides Information Untangling the Mysteries of Alzheimer's Disease Lary Walker, associate professor of neuroscience, discusses the most common cause of dementia -- Alzheimer's disease -- and a promising diagnostic tool to detect it. Walker also explains what happens to the brain when someone gets this disease, and why Alzheimer's is exclusive to humans. View Source June 10, 2010 Provides Information University of Tennessee CST effectively detects cognitive abnormalities associated with Alzheimer's disease Early detection is key to more effective treatment for Alzheimer's disease and other forms of cognitive impairment, and new research shows that a test developed at the University of Tennessee is more than 95 percent effective in detecting cognitive abnormalities associated with these diseases. View Source March 12, 2010 Provides Information USF receives patent for technology to improve treatment for neurodegenerative diseases The University of South Florida's Department of Neurosurgery and Brain Repair has been granted a patent for a cell transplantation procedure combining human umbilical cord blood (HUCB) cells and a sugar-alcohol compound called "mannitol" that may make a big difference in treating life-threatening neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, multiple sclerosis and stroke, among others. View Source July 8, 2010 Provides Information Using new approach, researchers find level of gene alters risk of Alzheimer's disease Using sophisticated techniques that scan the genomes of patients, researchers at the Mayo Clinic campus in Florida have found that a gene appears to either help protect against development of Alzheimer's disease, or promote the disorder depending on the level of gene in the brain. View Source March 15, 2010 Provides Information USPTO grants Vermillion Alzheimer's disease biomarker patent Vermillion, Inc., a molecular diagnostics company, today announced that the United States Patent and Trademark Office has issued a notice of allowance of a patent entitled "Biomarkers for Alzheimer's disease" to the Company. The patent claims are directed to biomarker combinations for the diagnosis and management of Alzheimer's disease and to the measurement of the biomarkers by a variety of methods, including mass spectrometry and immunoassay. View Source June 29, 2010 Provides Information V Venture Capital Group Invests in Start-Up Developing New Alzheimer's Test Foundation Venture Capital Group LLC hopes to help to lower the number of people living with Alzheimer's disease. The company has made an initial investment of $175,000, which can go up to $500,000 pending completion of certain milestones, to Durin Technologies Inc, a start-up company developing a test that requires only a drop of blood to diagnose the disease. View Source May 18, 2010 Provides Information Vitamin D and mental agility in elders At a time when consumer interest in health-enhancing foods is high, Agricultural Research Service (ARS)-funded scientists have contributed to a limited but growing body of evidence of a link between vitamin D and cognitive function. View Source June 25, 2010 Provides Information Vitamin D deficiency increases the risk of cognitive decline in the elderly A research team from the Peninsula Medical School, University of Exeter, has established the first clear link between vitamin D deficiency and the development of cognitive problems that are a key feature of dementia. View Source July 12, 2010 Provides Information W Watson commences shipment of generic Exelon Watson Pharmaceuticals, Inc. announced today that, under a settlement with Novartis Pharmaceuticals Corporation, Novartis Pharma AG, Novartis AG, Novartis International Pharmaceutical Ltd., and Proterra AG, Watson has commenced shipment of a generic version of Exelon® (rivastigmine tartrate) 1.5mg, 3mg, 4.5mg and 6mg capsules. View Source July 1, 2010 Provides Information Worsening Memory Associated With Later Alzheimer's Disease Subjective memory impairment, or mild deficits in memory that may or may not cause worry for an individual, appear to predict progression to more advanced stages of cognitive impairment and dementia. View Source April 7, 2010 Provides Information Z Zapping The Brain Back Into Action with Ultrasound Scientists at Arizone State University have developed a new method of non-surgical brain stimulation using pulsed ultrasound that enhances cognitive function in mice, and may one day be used to non-invasively treat patients with mental retardation, Alzheimer's disease and other CNS dysfunctions. In intact motor cortex in mice, ultrasound was found to stimulate action potentials and elicit motor responses comparable to those only previously achieved with implanted electrodes and related techniques. It also activates meaningful brain wave patterns and the production of brain-derived neurotrophic factor (BDNF) in the hippocampus - one of the most potent regulators of brain plasticity. View Source June 15, 2010 Provides Information
© 1997 - 2010 The MerchantStore