| 162 Health - Alzheimer Resources |
| 1 in 6 women and 1 in 10 men at risk for Alzheimer's disease in their lifetime
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| Researchers from Boston University School of Medicine (BUSM) have estimated that one in six women are at risk for developing Alzheimer's disease (AD) in their lifetime, while the risk for men is one in ten.
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March 19, 2008 |
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| A Theory Advanced: Alzheimer's Disease as Form of Diabetes
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| Investigators from the Northwestern University (da alma mater) discovered the mechanism that might explain an apparent resistance of brain neurons to insulin in patients suffering from the Alzheimer's dementia.
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October 3, 2007 |
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| Accidental Breakthrough Offers Hope for Alzheimer's Patients
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| An accidental breakthrough made during experimental brain surgery may help doctors unlock how memory works.
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January 30, 2008 |
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| Altering Brain's Lipid Metabolism Reduces Alzheimer's Plaques In Mice
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| Increasing levels of a protein that helps the brain use cholesterol may slow the development of Alzheimer's disease changes in the brain, according to researchers studying a mouse model of the disease at Washington University School of Medicine in St. Louis.
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January 22, 2008 |
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| Alzheimer's Association
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| The Alzheimer's Association is the leading voluntary health organization in Alzheimer care, support and research.
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| Alzheimer's Care: Grief Is Heaviest Burden For Caregivers
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| The hardest part of caring for loved ones with Alzheimer's-type disorders is not the everyday practical challenge, but rather the emotional impact of losing the patients' support and companionship as the disease robs them of their faculties, according to new research at the University of Indianapolis.
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March 10, 2008 |
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| Alzheimer's Disease As Case Of Brake Failure? Loss Of Protein Function In Neurons May Lead To Dementia
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| Rutgers researcher Karl Herrup and colleagues at Case Western Reserve University have discovered that a protein that suppresses cell division in brain cells effectively "puts the brakes" on the dementia that comes with Alzheimer's disease (AD). When the brakes fail, dementia results.
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June 25, 2008 |
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| Alzheimer's Disease Could Be A Third Form Of Diabetes
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| Insulin, it turns out, may be as important for the mind as it is for the body. Research in the last few years has raised the possibility that Alzheimer's memory loss could be due to a novel third form of diabetes.
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September 26, 2007 |
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| Alzheimer's Disease Risks Gender Specific: Women With Depression, Men With Stroke
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| The French researchers base their findings on almost 7000 people over the age of 65, drawn from the general population in three French cities.
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May 2, 2008 |
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| Alzheimer's Drug Nothing to Sneeze At
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| Used for Decades as an Allergy Drug, Dimebon now Shows Promise in Treating Alzheimer's Patients
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April 17, 2008 |
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| Alzheimer's helmet therapy hope
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| An experimental helmet is being tested by scientists as a treatment for Alzheimer's disease.
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January 25, 2008 |
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| Alzheimer's Molecule Is A Smart Speed Bump On The Nerve-cell Transport Highway
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| Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.
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January 22, 2008 |
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| Alzheimer's Risk Rises When Both Parents Have It
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| One parent with Alzheimer's disease is tough enough, but imagine the memory-robbing illness striking both parents -- and knowing chances are high you'll get it, too. A study of more than 100 families for the first time gauges the size of that risk.
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March 11, 2008 |
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| Alzheimer's Plaques Cleared Up In Mice
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| Researchers hope the new approach may one day overcome one of the biggest obstacles to development of new dementia medications -- the difficulty in finding drugs that can safely cross the blood-brain barrier.
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May 30, 2008 |
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| Alzheimer's vaccine clears amyloid plaques but has little effect on learning and memory impairment
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| A promising vaccine being tested for Alzheimer's disease does what it is designed to do -- clear beta-amyloid plaques from the brain -- but it does not seem to help restore lost learning and memory abilities, according to a University of California, Irvine study.
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April 7, 2008 |
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| Alzheimer's Vaccine Clears Plaque But Has Little Effect On Learning And Memory Impairment
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| A promising vaccine being tested for Alzheimer's disease does what it is designed to do -- clear beta-amyloid plaques from the brain -- but it does not seem to help restore lost learning and memory abilities
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April 5, 2008 |
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| Alzheimer's-associated Plaques Can Form In A Day, And Alzheimer's Symptoms Soon Follow
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| The amyloid plaques found in the brains of Alzheimer's disease patients may form much more rapidly than previously expected. Using an advanced microscopic imaging technique to examine brain tissue in mouse models of the devastating neurological disorder, researchers from the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND), working with colleagues from Washington University School of Medicine, find that plaques can develop in as little as a day and that Alzheimer's-associated neuronal changes appear soon afterwards.
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February 8, 2008 |
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| An Alzheimer's Vaccine? Promising Results In Mice
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| Could a new vaccine be the key to stopping Alzheimer's disease? A new research study from the Oklahoma Medical Research Foundation (OMRF) shows that immunization could offer a way to blunt or even prevent the deadly, memory-robbing disease.
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November 12, 2007 |
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| Anti-Alzheimer's Mechanism In Omega-3 Fatty Acids Found
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| It's good news that we are living longer, but bad news that the longer we live, the better our odds of developing late-onset Alzheimer's disease.
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January 2, 2008 |
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| Anti-inflammatory Drug Blocks Brain Plaques
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| Brain destruction in Alzheimer's disease is caused by the build-up of a protein called amyloid beta in the brain, which triggers damaging inflammation and the destruction of nerve cells.
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June 24, 2008 |
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| Antidepressant Shows Early Promise In Treating Agitation And Psychotic Symptoms Of Dementia
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| Researchers have found surprising evidence that an antidepressant (citalopram) may perform as well as a commonly-prescribed antipsychotic (risperidone) in the alleviation of severe agitation and psychotic symptoms of dementia.
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September 13, 2007 |
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| Arthritis Drug Shows Promise in Reversing Symptoms of Alzheimer's
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| A patient with Alzheimer's disease had their condition improve hugely just minutes after receiving a special injection of a prescription drug approved to treat psoriasis and rheumatoid arthritis and other conditions.
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January 10, 2008 |
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| Big belly could carry bigger dementia risk
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| Having a big belly in your 40s can boost your risk of getting Alzheimer's disease or other dementia decades later, a new study suggests.
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March 26, 2008 |
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| Biological Marker For Alzheimer's Holds Promise For Earlier Diagnosis And Treatment
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| Researchers at Robarts Research Institute at The University of Western Ontario have found clear evidence that increases in the size of the brain ventricles are directly associated with cognitive impairment and Alzheimer's disease.
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July 12, 2008 |
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| Blood Pressure Drug May Curb Brain Damage From Alzheimer's, Depression And Schizophrenia
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| A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia.
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November 7, 2007 |
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| Blood Pressure Drug Might Work Against Alzheimer's
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| The blood pressure drug valsartan shows the ability to reduce Alzheimer's disease-like symptoms in mice.
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October 25, 2007 |
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| Bracelet Helps Caregivers Keep Track of Alzheimer's Patients
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| It looks like a toy, but the bracelet locked around Bob Melnick's wrist gives his wife some peace of mind: If this Alzheimer's patient wanders off and gets lost, he's wearing a tracking beacon to help bring him home.
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August 12, 2007 |
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| Brain gene map: a route to Alzheimer's cure?
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| A new catalogue of genes, and the proteins they trigger in the brain, could help scientists develop new treatments for neurological diseases such as Alzheimer's.
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November 6, 2007 |
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| Brain Implants Relieve Alzheimer's Damage
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| Genetically engineered cells implanted in mice have cleared away toxic plaques associated with Alzheimer's disease.
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August 30, 2007 |
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| Brain trick Offers Treatment Hope For Alzheimer's
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| Scientists in the UK and Canada have made a significant step forward in the search for new drugs to treat Alzheimer's disease.
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July 3, 2008 |
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| Calpain Inhibitors Never Forget: Improving Memory In Alzheimer's Disease Mice
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| Overactivation of proteins known as calpains, which are involved in memory formation, has been linked to Alzheimer disease.
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July 6, 2008 |
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| Can Tomatoes Carry An Oral Vaccine Against Alzheimer's Disease?
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| The humble tomato could be a suitable carrier for an oral vaccine against Alzheimer's disease, according to HyunSoon Kim from the Korea Research Institute of Bioscience and Biotechnology (KRIBB) in Korea and colleagues from Digital Biotech Inc. and the Department of Biological Science at Wonkwang University.
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July 9, 2008 |
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| Cell therapies for diabetes, cancer
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| Therapies using stem cell transplants are advancing promising treatments for such conditions as Alzheimer's Disease, neurological diseases and spinal cord injury, and heart disease.
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March 21, 2008 |
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| Charity backs dementia taggings
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| Proposed electronic tagging of dementia sufferers, with their agreement, has been backed by the Alzheimer's Society.
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December 27, 2007 |
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| Childhood Lead Exposure Linked To Alzheimer's Disease
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| A University of Rhode Island pharmacy professor has found for the first time evidence of Alzheimer's-like disease in monkeys that were exposed to lead as infants.
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February 20, 2008 |
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| Children With Alzheimer's Disease Risk Gene Show Reduced Cognitive Function
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| Children who possess a gene known to increase the risk of Alzheimer's disease already show signs of reduced cognitive function, an Oregon Health & Science University study has found.
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November 6, 2007 |
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| Cholesterol Drug May Ward Off Alzheimer's
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| Taking cholesterol-lowering statins may help to prevent Alzheimer's disease, a study has suggested for the first time.
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August 28, 2007 |
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| Cholesterol lowering statins may also reduce the risk of Alzheimer's
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| Researchers in the United States say they believe cholesterol-lowering drugs may reduce the risk of Alzheimer's.
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August 28, 2007 |
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| Cholesterol Metabolism Links Early- And Late-onset Alzheimer's Disease
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| Although the causes of Alzheimer's disease are not completely understood, amyloid-beta (A-beta) is widely considered a likely culprit -- the "sticky" protein clumps into plaques thought to harm brain cells.
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October 9, 2007 |
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| Clean living conscientious types less prone to Alzheimer's
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| According to the latest research from the United states if you are a clean living conscientious person you are less likely to develop Alzheimer's disease.
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October 2, 2007 |
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| Cocktail Therapy For Alzheimer's Disease? Works for Gerbils
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| A dietary cocktail that includes a type of omega-3 fatty acid can improve memory and learning in gerbils, according to the latest study from MIT researchers that points to a possible beverage-based treatment for Alzheimer's and other brain diseases.
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July 9, 2008 |
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| Cold Sore Virus Linked to Alzheimer's Disease, Study Finds
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| New research suggests that people who suffer from a cold sore virus may be more likely to develop Alzheimer's disease later in life.
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November 1, 2007 |
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| Consumption Of Fruits May Reduce Risk Of Alzheimer's Disease
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| Apples, bananas, and oranges are the most common fruits in both Western and Asian diets, and are important sources of vitamins, minerals, and fiber. A new study in the Journal of Food Science explores the additional health benefits of these fruits and reveals they also protect against neurodegenerative diseases, including Alzheimer's Disease.
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January 31, 2008 |
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| Copper Damages Protein That Defends Against Alzheimer's
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| The new findings demonstrate one way in which copper might contribute to the development of the disease, though scientists say much more research needs to be done to clarify what role, if any, copper ultimately plays.
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November 8, 2007 |
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| Cup Of Coffee A Day Could Help Protect Against Alzheimer's Disease
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| A daily dose of caffeine blocks the disruptive effects of high cholesterol that scientists have linked to Alzheimer's disease. A study in the open access publication, Journal of Neuroinflammation revealed that caffeine equivalent to just one cup of coffee a day could protect the blood-brain barrier (BBB) from damage that occurred with a high-fat diet.
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April 3, 2008 |
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| Dementia Diagnosis Brings Relief, Not Depression
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| When it comes to a diagnosis of Alzheimer's disease, what you don't know may not kill you, but knowing the truth as soon as possible appears to be the better approach — one that may improve the emotional well-being of both patients and their caregivers.
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March 5, 2008 |
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| Dementia Screening In Primary Care: Is It Time?
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| Primary care physicians should focus on "dementia red flags" rather than routinely screen individuals with no dementia symptoms just because they've reached a certain age.
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November 28, 2007 |
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| Depression Increases Risk Of Alzheimer's Disease, Study Suggests
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| People who have had depression are more likely to develop Alzheimer's disease than people who have never had depression, according to a study published in the April 8, 2008, issue of Neurology.
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April 10, 2008 |
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| Diabetes In Mid-life Linked To Increased Risk Of Alzheimer's Disease
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| Men who develop diabetes in mid-life appear to significantly increase their risk of developing Alzheimer's disease, according to a long-term study published in the April 9, 2008, online issue of Neurology.
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April 10, 2008 |
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| Diabetes Link To Alzheimer's Disease Explained
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| Diabetic individuals have a significantly higher risk of developing Alzheimer's disease but the molecular connection between the two remains unexplained. Now, researchers at the Salk Institute for Biological Studies identified the probable molecular basis for the diabetes -- Alzheimer's interaction.
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May 2, 2008 |
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| Discovery of toxic key to Alzheimer's disease memory loss
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| Using new scientific techniques, scientists have unlocked the cascade of molecular events that lead to Alzheimer's disease.
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June 26, 2008 |
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| Drugs May Not Delay Onset Of Dementia
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| Researchers have examined the evidence in favour of giving people considered to be close to developing dementia the drugs that are most commonly used to treat the condition itself.
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November 27, 2007 |
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| Dual action Alzheimer's drug hope
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| Experimental drugs are being hailed as a potentially exciting step forward in the treatment of Alzheimer's.
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June 11, 2008 |
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| Early detection of Alzheimer's in the pipeline
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| A boost of $1.6 million for new research into Alzheimer's Disease for Australian scientists means that the early detection of the disease could well be in the pipeline.
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June 19, 2008 |
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| Early Diagnosis Gives Voice to Once-Voiceless Alzheimer's Patients
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| Don Hayen has a handy way of deflecting the instant pity that comes when he reveals his Alzheimer's disease: "But I haven't lost my keys all day," he quickly jokes. Hayen is part of a growing new movement in Alzheimer's: Patients diagnosed early enough to still be articulate and demand better care and better research.
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June 3, 2008 |
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| Effects Of Progesterone On Alzheimer's Disease
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| he first study on progesterone and Alzheimer's disease has found no clear preventive benefit for the widely prescribed hormone in an animal model.
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November 28, 2007 |
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| End-stage dementia patients deserve the same access to palliative care as people with cancer
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| There is an urgent need to improve end-of-life care for older people in the final stages of dementia, according to an international review published in the May issue of Journal of Clinical Nursing.
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May 12, 2008 |
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| Enzyme Beneficial to Alzheimer's Plays Darker Role in Other Dementia
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| An enzyme shown to help suppress development of Alzheimer's disease appears to hasten progress of a related but far less common type of dementia, according to a new study.
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April 23, 2008 |
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| Excessive Consumption of Sugary Drinks Linked Alzheimer's Disease
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| If you want to keep your mind sharp, you may want to lay off the soda. Excessive drinking of sugary beverages may increase the risk of Alzheimer's disease, according to a new study by the American Society for Biochemistry and Molecular Biology.
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December 7, 2007 |
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| Exercise may slow Alzheimer's brain atrophy
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| Physically fit patients had less cerebral shrinkage, study shows
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July 14, 2008 |
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| Experts say spend more on dementia or expect a crisis
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| Scientists in both Australia and Britain are calling for more funding for dementia in order to avert a health care crisis in the future.
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June 18, 2008 |
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| ExpIND process speeds Alzheimer's drug research
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| Researchers are actively cutting the time and cost it normally takes to develop radiopharmaceuticals by taking advantage of "Exploratory Investigational New Drug" (ExpIND), an FDA-sanctioned procedure that enhances post-discovery drug development while observing scientific and patient safety standards.
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June 16, 2008 |
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| Families Shed Light On Likely Causative Gene For Alzheimer's
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| The genetic profile of two large Georgia families with high rates of late-onset Alzheimer's disease points to a gene that may cause the disease, researchers say.
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May 15, 2008 |
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| FDA tells drug giant to come clean about Alzheimer's drug
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| The Food and Drug Administration (FDA) in the U.S. has warned a major drug company about misleading the medical profession over a drug for dementia.
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August 15, 2007 |
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| Fibrin may be new target for Alzheimer's drugs
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| Despite the rapid rise of Alzheimer's disease - the Alzheimer's Association predicts as many as 7.7 million cases by 2030 - there are no preventative treatments available, few in the pharmaceutical pipeline, and those drugs being developed all share the same two molecular targets.
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August 15, 2007 |
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| First Conclusive Evidence Of Alzheimer's-like Brain Tangles In Nonhuman Primates Found
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| The unprecedented finding has the potential to move the scientific community one step closer to understanding why age-related neurodegenerative diseases, such as Alzheimer's disease, are uniquely human and seem to never fully manifest in other species--including our closest evolutionary relative, the chimpanzee.
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May 15, 2008 |
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| First Diagnostic Test For Alzheimer's And Parkinson's Disease On The Horizon
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| Manufacturer, Oklahoma-based proteomics company, Power3 Medical Products, said it plans to sell the test, NuroPro, which would be the first diagnostic test for neurodegenerative diseases on the market, in Greece by Q3 with further plans for it to go on the US market by late Q3 or Q4."
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April 7, 2008 |
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| Fruit for Alzheimer's
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| Apples, bananas, and oranges are the most common fruits in both Western and Asian diets, and are important sources of vitamins, minerals, and fiber.
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February 4, 2008 |
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| Ginkgo biloba and dementia
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| Taking the supplement ginkgo biloba had no clear-cut benefit on the risk of developing memory problems, according to a study published in the February 27, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.
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February 28, 2008 |
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| Glaucoma, Alzheimer's Disease Linked
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| Scientists Spot the Same Protein in Both Diseases; Finding May Inspire New Glaucoma Treatments.
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August 6, 2007 |
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| Grape Seed Extract May Reduce Cognitive Decline Associated With Alzheimer's Disease
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| A compound found in grape seed extract reduces plaque formation and resulting cognitive impairment in an animal model of Alzheimer's disease, new research shows.
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June 18, 2008 |
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| High Blood Pressure Or Irregular Heartbeat Linked To Alzheimer's Disease Progression
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| Alzheimer's disease (AD) may progress more rapidly in people with high blood pressure or a form of irregular heartbeat, atrial fibrillation.
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November 8, 2007 |
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| High Cholesterol In Your 40s Increases Risk Of Alzheimer's Disease
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| People with high cholesterol in their early 40s are more likely to develop Alzheimer's disease than those with low cholesterol, according to new research.
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April 16, 2008 |
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| How Neural Sludge Accumulates In Alzheimer's Disease
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| Researchers have identified a key mechanism by which the protein sludge that kills brain cells accumulates in Alzheimer's disease (AD). Their findings in mice offer clues to treating AD and also could explain why memory centers of the brain are most affected in the disease.
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April 11, 2008 |
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| How One Mutation Tips Biochemistry To Cause Alzheimer's Disease
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| Your fate can be determined by tiny events. Imagine you live in the city and you walk everywhere to get exercise -- you are healthy and not afraid of getting mugged.
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May 12, 2008 |
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| Huperzine A for Alzheimer's disease
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| Existing evidence suggests that patients with Alzheimer's disease who have taken Huperzine A have improved general cognitive function, global clinical status, functional performance and reduced behavioural disturbance compared to patients taking placebos.
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April 17, 2008 |
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| Hypertension Drugs May Prevent and Treat Alzheimer's
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| Drugs commonly used to treat hypertension, may be successful in preventing Alzheimer’s disease, according to a new study published in The Journal of Clinical Investigation.
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October 26, 2007 |
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| Hypertension may heighten effects of Alzheimer's disease
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| Having hypertension, or high blood pressure, reduces blood flow in the brains of adults with Alzheimer's disease, according to a new study presented at the annual meeting of the Radiological Society of North America (RSNA).
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December 2, 2007 |
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| Hypertension or atrial fibrillation linked to Alzheimer's disease progression
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| While current medications for Alzheimer's disease are effective for some patients in slowing the rate of AD progression, many patients do not benefit from the treatments or cannot tolerate them, says lead researcher Michelle M. Mielke, Ph.D., of the Department of Psychiatry and Behavioral Sciences at The Johns Hopkins University School of Medicine.
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November 6, 2007 |
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| Ibuprofen linked to lower risk of Alzheimer's
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| For the study, researchers identified 49,349 US veterans age 55 and older who developed Alzheimer's disease and 196,850 veterans without dementia. The study examined over five years of data and looked at the use of several non-steroidal anti-inflammatory drugs (NSAIDs).
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May 5, 2008 |
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| Link Between Alzheimer's And Stroke Illuminated
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| For years, neuroscientists have known that the risk of Alzheimer's disease is nearly doubled among people who have had a stroke. Now researchers at Columbia University Medical Center have found a process in the brain that may help explain the link between Alzheimer's and stroke.
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March 19, 2008 |
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| Linking two molecular pieces may offer new approaches to treating Alzheimer's disease
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| Researchers have uncovered a biological link between the protein whose mutation causes early-onset Alzheimer's disease (AD) and a gene variant linked to late-onset AD.
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October 4, 2007 |
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| Lipids in the brain an important factor for Alzheimer's disease
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| As the most common form of dementia in the Western world, Alzheimer's disease carries enormous implications for our ageing society.
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December 11, 2007 |
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| Low Education Level Linked To Alzheimer's, Study Shows
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| People who don't finish high school are at a higher risk of developing dementia and Alzheimer's disease compared to people with more education, regardless of lifestyle choices and characteristics such as income, occupation, physical activity and smoking
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October 1, 2007 |
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| Lowering blood pressure reduces the risk of dementia
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| New research suggests that lowering blood pressure in older people could reduce their chances of dementia by 13%.
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July 8, 2008 |
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| Married her friend, living with a monster
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| Joan Gershman, 59, does not mince words when describing how Alzheimer's disease has affected her marriage.
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February 11, 2008 |
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| Maternal link to Alzheimer's disease found
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| People who have a mother with Alzheimer's disease appear to be at higher risk for getting the disease than those individuals whose fathers are afflicted.
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November 7, 2007 |
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| Mechanism Explains Calcium Abnormalities In Alzheimer's Brain
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| A new study uncovers a mechanism that directly links mutations that cause early onset Alzheimer's disease (AD) with aberrant calcium signaling.
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June 27, 2008 |
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| Mechanism Explains Link Between Apolipoprotein E And Alzheimer's Disease
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| Scientists have discovered a previously unknown mechanism by which apolipoprotein E, a molecule whose mutation is linked to Alzheimer's disease (AD), stimulates degradation of sticky amyloid beta (Aß) protein within the brain. The research, published by Cell Press in the June 12 issue of the journal Neuron, may lead to a powerful new therapy for this devastating disease.
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June 13, 2008 |
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| Memory Loss in Hyperactive State With Alzheimer's
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| Memory loss, where the brain deletes inconsequential information, is in a hyperactive state in people with Alzheimer's disease, a new study suggests.
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March 7, 2008 |
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| Mice With Alzheimer's Disease Suffer 'Silent' Seizures
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| Mice genetically engineered to have a disease like Alzheimer's have "silent" seizures that appear related to cellular changes involving the excess accumulations of the protein amyloid beta.
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September 9, 2007 |
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| Microgrid Allows Simultaneous Study of Multiple Variables and Could Improve Understanding, Diagnosis of Alzheimer's and Other Diseases
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| Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have developed a method for correlating the results of microscopic imaging techniques in a way that could lead to improved understanding, diagnosis, and possibly treatment of a variety of disease conditions, including Alzheimer's disease.
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October 11, 2007 |
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| Mild Alzheimer's Patients Show Rapid Decline In Financial Skills And Increased Vulnerability To Fraud, Over One Year
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| New research from UAB (University of Alabama at Birmingham) shows that patients with mild Alzheimer's disease (AD) have a dramatic decline in their ability to make financial decisions over a one year period. The findings have strong implications for caregivers and health care providers in the areas of estate planning and fraud prevention.
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February 11, 2008 |
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| Molecular Imaging Sheds New Light On Progression Of Alzheimer's Disease
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| Recent research suggests that the use of molecular imaging in the management of neurodegenerative disease, particularly for early diagnosis of AD, will enable researchers to monitor the progression of the disease, identifying those at risk and assessing the effectiveness of new therapies.
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June 19, 2008 |
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| Moss Protein Plays Role In Alzheimer's Disease, Researchers Believe
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| The gene presenilin (PS) in mammals provides the catalytic activity for an enzyme called gamma secretase, which cleaves, or cuts, important proteins Notch, Erb4 and the amyloid precursor protein (APP), all key components of communication channels that cells use to arbitrate functions during development.
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February 12, 2008 |
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| Moss Protein Plays Role In Alzheimer's Disease, Researchers Believe
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| Preventing Alzheimer's disease is a goal of Raphael Kopan, Ph.D., professor of molecular biology and pharmacology at the Washington University School of Medicine. The moss plant Physcomitrella patens studied in the laboratory of Ralph S. Quatrano, Ph.D., the Spencer T. Olin Professor and chair of the biology department on WUSTL's Danforth Campus, might inch Kopan toward that goal. Here's how.
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February 13, 2008 |
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| MRI Technology Could Speed Up Early Diagnosis of Alzheimer's
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| One of the most widely used tools in radiology could help physicians more accurately diagnose Alzheimer's disease at an early stage, the journal Radiology reported in its July issue.
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June 25, 2008 |
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| Mutation in TDP-43 gene may play role in common dementia
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| Scientists at Washington University School of Medicine in St. Louis have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig's disease.
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February 21, 2008 |
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| Neuron to publish Prana's PBT2 preclinical research on Alzheimer's disease
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| The article titled "Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxyquinoline analogs" is associated with decreased interstitial Abeta" appears in the current edition of the prestigious scientific journal Neuron, and can be viewed online.
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July 10, 2008 |
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| New Alzheimer's patent by Affiris
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| Affiris GmbH has secured another Europe-wide patent for an innovative method of treating Alzheimer's disease. This new blood-cleansing method is similar to dialysis and is designed to reduce the amount of harmful protein deposits in the brain. It is based on the AFFITOME technology established by Affiris, which was patented in October 2007 for an Alzheimer's vaccine.
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February 27, 2008 |
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| New Alzheimer's Treatment Completes First Phase Of Testing
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| A molecule designed by a Purdue University researcher to stop the debilitating symptoms of Alzheimer's disease has been shown in its first phase of clinical trials to be safe and to reduce biomarkers for the disease.
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January 28, 2008 |
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| New Brain Marker Shows Promise For Predicting Future Alzheimer's Disease
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| Duke University Medical Center researchers have used imaging technology to identify a new marker that may help identify those at greatest risk for cognitive decline and the development of Alzheimer's disease.
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November 4, 2007 |
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| New clue to Alzheimer's found in form of protein
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| Researchers have uncovered a new clue to the cause of Alzheimer's disease. The brains of people with the memory-robbing form of dementia are cluttered with a plaque made up of beta-amyloid, a sticky protein.
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June 22, 2008 |
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| New Compound Identifies Alzheimer's Disease Brain Toxins
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| A groundbreaking study conducted by University of Pittsburgh Alzheimer's disease researchers reported in the journal Brain confirms that Pittsburgh Compound-B (PiB) binds to the telltale beta-amyloid deposits found in the brains of patients with Alzheimer's disease. The finding is a significant step toward enabling clinicians to provide a definitive diagnosis of Alzheimer's disease in living patients.
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March 28, 2008 |
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| New Drug Discovery Tool For Alzheimer's Disease Discovered
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| An article in the Journal of Alzheimer's Disease presents a detailed characterization of a new drug discovery tool for Alzheimer's disease. It demonstrates that an abnormal form of tau protein, as it occurs in Alzheimer's disease, can be produced in very simple cell models in an unambiguous way.
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April 29, 2008 |
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| New drug may restore memory with Alzheimer's disease
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| Alzheimer's creeps up on patients and their families, robbing more than half of all Americans over age 85 of their memory and ability to care for themselves.
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November 14, 2007 |
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| New drug offers hope for Alzheimer's victims
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| An experimental drug to treat Alzheimer's Disease has been seen to be effective in trials with Alzheimer's patients.
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June 18, 2008 |
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| New Drug Reverses Alzheimer's Disease Within Days In Mouse Models
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| Scientists report a remarkable improvement in Alzheimer's transgenic mice following treatment with a new drug. The study provides the first demonstration that an ionophore, a compound that transports metal ions across cell membranes, can elicit rapid and pronounced improvement in neuropathology and cognitive function in mouse models of Alzheimer's Disease (AD).
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July 10, 2008 |
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| New Method Developed To Identify Genetic Determinants Of Alzheimer's Disease
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| A rapid and accurate DHPLC assay for determination of apolipoprotein E genotypes has been developed by researchers from the Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China. This assay combines PCR and DHPLC and can be used to conduct efficient genotyping of the human population, which in turn will help in the diagnosis and treatment of Alzheimer's disease.
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January 16, 2008 |
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| New Target For Alzheimer's Disease Identified
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| Alzheimer's disease (AD) is an incurable disease that is increasing in prevalence and will increase even more rapidly as the Baby Boom generation enters the age of highest risk. The available AD drugs are only partially effective in some patients. New strategies are urgently needed.
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May 8, 2008 |
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| New System Detects Dementia Risk Among Highly Educated Older Adults
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| A different cutoff point on an existing mental function assessment may more effectively assess the risk of dementia in highly educated older adults, according to a new article.
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July 14, 2008 |
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| New way to treat Alzheimer's
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| A team of scientists led by professor Kiminobu Sugaya at the University of Central Florida may have found a new way to treat Alzheimer's disease.
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August 7, 2007 |
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| Nicotine drug 'may slow dementia'
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| Nicotine-based drugs may help delay the moment a person with dementia has to enter a care home, say researchers.
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July 13, 2008 |
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| Novartis Receives EU's Approval for Alzheimer's Patch
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| Following FDA's decision to approve the Exelon skin patch from Novartis, the EU certifies it in Europe as well.
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September 25, 2007 |
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| Obesity Can Increase Dementia Risk By Up To 80 Percent
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| Their analysis of published obesity and dementia prospective follow-up studies over the past two decades shows a consistent relationship between the two diseases.
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May 7, 2008 |
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| Offspring Of Parents Who Both Have Alzheimer's Disease May Be More Likely To Develop The Illness
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| Adult-age offspring of parents who have both been diagnosed with Alzheimer's disease appear to have an increased risk of developing the disease compared with the general population, according to a new report.
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March 11, 2008 |
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| Oregon Boy, 10, Suffering From Deadly Childhood 'Alzheimer's'
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| A 10-year-old Salem boy is suffering from a rare genetic disorder that is causing a deadly cholesterol overload in some of his internal organs, it is reported by the Statesman Journal.
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February 29, 2008 |
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| Overexposure to metals and Alzheimer's disease
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| A multi-institutional team of researchers led by Emory University has defined for the first time how metal ions bind to amyloid fibrils in the brain in a way that appears toxic to neurons.
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August 7, 2007 |
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| Paradoxical Alzheimer's Finding May Shed New Light On Memory Loss
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| Do you remember the seventh song that played on your radio on the way to work yesterday? Most of us don't, thanks to a normal forgetting process that is constantly "cleaning house" -- culling inconsequential information from our brains. Researchers at the Buck Institute now believe that this normal memory loss is hyper-activated in Alzheimer's disease (AD) and that this effect is key to the profound memory loss associated with the incurable neurodegenerative disorder.
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March 16, 2008 |
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| Paradoxical Alzheimer's finding may provide better understanding of memory loss
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| Most of us don't, thanks to a normal forgetting process that is constantly "cleaning house" - culling inconsequential information from our brains. Researchers at the Buck Institute now believe that this normal memory loss is hyper-activated in Alzheimer's disease (AD) and that this effect is key to the profound memory loss associated with the incurable neurodegenerative disorder.
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March 10, 2008 |
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| People With Dementia Survive On Average Four And A Half Years After Diagnosis
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| People with dementia survive an average of four and a half years after diagnosis, with age, sex, and existing disability all having an influence on life expectancy, finds a study published on the British Medical Journal website.
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January 11, 2008 |
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| PET Scan Distinguishes Alzheimer's From Other Dementia
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| A PET scan (positron emission tomography) that measures uptake of sugar in the brain significantly improves the accuracy of diagnosing a type of dementia often mistaken for Alzheimer's disease, a study led by a University of Utah dementia expert has found.
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November 1, 2007 |
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| Plants' Flavonoids Have Beneficial Effect On Alzheimer's Disease
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| A set of molecules found in certain plants appears to have a beneficial effect in brain tissue associated with Alzheimer's disease, according to a new study conducted in mice. Luteolin and diosmin reduced levels of amloid-beta, which forms the sticky deposits that build up in the brains of patients with Alzheimer's disease.
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May 8, 2008 |
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| Portable Device Quickly Detects Early Alzheimer's
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| The latest medications can delay the onset of Alzheimer's disease, but none are able to reverse its devastating effects. This limitation often makes early detection the key to Alzheimer's patients maintaining a good quality of life for as long as possible.
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January 17, 2008 |
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| Potential Alzheimer's Disease Drug Target Identified
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| In findings with the potential to provide a therapy for Alzheimer's disease patients where none now exist, a researcher at the University of California, San Diego and colleagues have demonstrated in mice a way to reduce the overproduction of a peptide associated with the disease. The study, which showed substantial improvement in memory in an animal model of Alzheimer's disease, was led by Vivian Y. H. Hook, Ph.D., professor of the Skaggs School of Pharmacy and Pharmaceutical Sciences and professor of neurosciences, pharmacology and medicine at the UCSD School of Medicine, together with American Life Science Pharmaceuticals of San Diego.
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March 18, 2008 |
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| Pratchett has Alzheimer's disease
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| Author Terry Pratchett is suffering from a rare form of early Alzheimer's disease, it has been revealed.
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December 12, 2007 |
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| Pratchett funds Alzheimer's study
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| Best-selling fantasy author Terry Pratchett is to donate $1m for research into Alzheimer's disease.
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March 13, 2008 |
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| Protein May Protect Against Alzheimer's Disease
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| Scientists at The Scripps Research Institute report that a protein capable of producing what has been called "Alzheimer's of the heart" has been found to protect against development of Alzheimer's disease in the brain in rodent models.
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February 22, 2008 |
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| Public opinion about Alzheimer's disease among Blacks, Hispanics, and Whites
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| Alzheimer's disease is still a mystery to people of different races and a large percentage of people across the board are unaware that treatments are available to reduce symptoms.
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September 19, 2007 |
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| Relatives of patients with Parkinson's disease may have an increased risk of developing dementia
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| Parkinson's disease is characterized by a decline in the functions of the central nervous system, such as motor skills and speech. Several studies have shown an increased risk of dementia in first-degree relatives of Parkinson's disease patients, while other studies have not confirmed the association, according to background information in the article.
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October 9, 2007 |
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| Researchers Identify Brain Network That May Help Prevent Or Slow Alzheimer's
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| Columbia University Medical Center researchers have identified a brain network within the frontal lobe that is associated with cognitive reserve, the process that allows individuals to maintain function despite brain function decline due to aging or Alzheimer's disease.
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August 21, 2007 |
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| Researchers Say Vaccine May Prevent, Slow Alzheimer's Disease
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| Scientists at the Oklahoma Medical Research Foundation in Oklahoma City have developed a vaccine they hope can slow down or even prevent Alzheimer's disease.
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November 13, 2007 |
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| Reversal Of Alzheimer's Symptoms Within Minutes In Human Study
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| An extraordinary new scientific study, which for the first time documents marked improvement in Alzheimer's disease within minutes of administration of a therapeutic molecule, has just been published in the Journal of Neuroinflammation.
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January 9, 2008 |
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| Reversing The Signs Of Alzheimer's
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| Scottish scientists are one step further to finding a cure for Alzheimer's, thanks to the development of a compound which reverses signs of the disease.
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August 6, 2007 |
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| Review of Memantine for Alzheimer's
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| In a study published this month in the Journal of Alzheimer's Disease, researchers from the University of Aberdeen report that the drug memantine, used for the treatment of Alzheimer's disease and praised as "the first and only representative of a new class of Alzheimer drugs" works in fact similar to other existing compounds, and is beneficial only in a narrow concentration range.
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January 11, 2008 |
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| Scientists Automate Alzheimer's Identification
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| Researchers from the Wellcome Trust Centre for Neuroimaging at University College London used computers to locate gray matter in MR images of potential Alzheimer's patients, and based on the data, the machines were then able to correctly make a diagnosis with a higher success rate than human doctors.
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March 3, 2008 |
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| Scientists identify possible Alzheimer's gene
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| Gene hampers cell's ability to absorb calcium, raises risk by 45 percent
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June 25, 2008 |
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| Scientists take plumber's approach to Alzheimer's
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| Scientists are trying a plumber's approach to rid the brain of the amyloid buildup that plagues Alzheimer's patients: Simply drain the toxic protein away.
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August 13, 2007 |
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| Scientists use shared genome data to confirm SORL1 gene linked to Alzheimer's
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| Until recently, only one of the approximately 30,000 genes in the human genome has been linked to risk of late-onset Alzheimer's disease (AD).
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October 29, 2007 |
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| Second Genetic Risk Factor For Late-onset Alzheimer's Disease Found
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| Researchers have discovered the second, strong genetic risk factor for developing late-onset Alzheimer's disease, according to a new report in the June 27th issue of the journal Cell, a Cell Press publication.
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June 26, 2008 |
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| Short Arms And Legs Linked To Risk Of Dementia
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| People with shorter arms and legs may be at a higher risk for developing dementia later in life compared to people with longer arms and legs, according to a study published in the May 6, 2008, bonus issue of Neurology, the medical journal of the American Academy of Neurology.
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May 5, 2008 |
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| Simple blood test 90% accurate in predicting Alzheimer's
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| A new blood test which has been developed by scientists in California may enable doctors to predict just who is likely to develop the the degenerative brain disease Alzheimer's.
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October 15, 2007 |
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| Six years advance warning of Alzheimer's
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| One of the most distressing aspects of Alzheimer's disease is the difficulty in determining whether mild memory problems are the beginning of an inevitable mental decline.
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October 15, 2007 |
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| Smoking ups Alzheimer's risk by 50%
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| According to a new Dutch study people over the age of 55 who are smokers put themselves at a far greater risk of developing dementia than people who do not smoke.
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September 5, 2007 |
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| Statin Treatment May Curb Alzheimer's Brain Changes
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| People who take statin drugs may be less likely to develop the brain changes that signal Alzheimer's disease, according to a study published in the August 28, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.
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August 29, 2007 |
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| Staving Off Alzheimer's Disease With The Right Diet, Prescriptions
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| New studies reveal the effects of environmental substances on the promotion or slowing of symptoms associated with Alzheimer's disease.
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November 13, 2007 |
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| Study looks at anesthetic desflurane and Alzheimer's
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| In studies of human brain cells, the widely-used anesthetic desflurane does not contribute to increased production of amyloid-beta protein; however, when combined with low oxygen conditions, it can produce more of this Alzheimer's associated protein.
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April 27, 2008 |
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| The Emerging Role Of Infection In Alzheimer's Disease
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| A number of chronic diseases are in fact caused by one or more infectious agents. For example, stomach ulcers are caused by Helicobacter pylori, chronic lung disease in newborns and chronic asthma in adults are both caused by Mycoplasmas and Chlamydia pneumonia, while some other pathogens have been associated with atherosclerosis.
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May 25, 2008 |
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| The Good And The Bad Of A Potential Alzheimer's Target
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| Research in fruit flies has shown that enhancing the production of a protein called neprilysin can reduce the formation of plaques and neuron death associated with Alzheimer's, at the expense of reducing the flies' lifespan.
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June 29, 2008 |
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| Tooth Loss May Predict Late-Life Dementia
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| Tooth loss may predict the development of dementia late in life, according to research published in the October issue of The Journal of the American Dental Association.
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October 11, 2007 |
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| Umbilical Cord Blood Cell Therapy May Treat Cognitive Decline Of Alzheimer's Disease
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| A novel strategy based on targeted immune suppression using human umbilical cord blood cells may improve the pathology and cognitive decline associated with Alzheimer's disease, based on the results of a study in a mouse model of this currently untreatable neurodegenerative condition, as described in a new report in Stem Cells and Development.
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March 27, 2008 |
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| Use Of Bright Lighting May Improve Dementia Symptoms For Elderly Persons
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| The use of daytime bright lighting to improve the circadian rhythm of elderly persons was associated with modest improvement in symptoms of dementia, and the addition of the use of melatonin resulted in improved sleep, according to a new study.
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June 11, 2008 |
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| Vaccine Thwarts The Tangles Of Alzheimer's
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| A new study by NYU Medical Center researchers shows for the first time that the immune system can combat the pathological form of tau protein, a key protein implicated in Alzheimer's disease.
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August 24, 2007 |
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| Vaccine suppresses aggregates of tau protein - implications for Alzheimer's
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| A new study by NYU Medical Center researchers shows for the first time that the immune system can combat the pathological form of tau protein, a key protein implicated in Alzheimer's disease.
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August 22, 2007 |
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| Vitamin E May Up Alzheimer's Survival
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| Study Shows High Doses of Vitamin E May Lower Death Rate for Alzheimer's Patients.
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April 15, 2008 |
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| Weight loss in women may be a precursor for Alzheimer's
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| Scientists in the U.S. say they suspect that women who develop Alzheimer's disease or other forms of dementia may start losing weight at least a decade before being diagnosed with the condition.
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August 21, 2007 |
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| What Causes Alzheimer's? Researchers Tie Beta-amyloids To Brain Dysfunction
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| Researchers tied the accumulation of the toxic brain protein beta-amyloid to Alzheimer's disease, according to a study reported at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.
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June 7, 2007 |
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| What causes the leaks that develop in blood vessels in Alzheimer's disease?
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| Scientists at the University of Bristol are investigating what causes the leaks that develop in blood vessels in Alzheimer's disease, thanks to funding from the UK's leading dementia research charity.
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November 25, 2007 |
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| Wine May Protect Against Dementia, Study Suggests
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| here may be constituents in wine that protect against dementia. This is shown in research from the Sahlgrenska Academy at University of Gothenburg in Sweden.
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April 13, 2008 |
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| Women Lose Weight at Least a Decade Before Getting Dementia
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| A new study reveals that weightloss in some women may be a precursor to dementia.
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August 21, 2007 |
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| Women over 90 significantly more likely to have dementia than men of the same age
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| Women over 90 are significantly more likely to have dementia than men of the same age, according UC Irvine researchers involved with the 90+ Study, one of the nation's largest studies of dementia and other health factors in the fastest-growing age demographic.
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July 3, 2008 |
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