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| 53 Health - Arthritis Resources |
| Aerobic exercise safe and effective for rheumatoid arthritis patients |
| Researchers from the University of Grenoble Medical School in France determined that cardio-respiratory aerobic exercise is safe for patients with stable rheumatoid arthritis (RA). The team found that RA patients who exercised regularly had improved function, less joint pain, and greater quality of life. |
| View Source | June 24, 2010 | Provides Information |
| Alcohol Associated With Lower Risk of Arthritis |
| Doctors Caution Against Drinking Alcohol to Reduce Arthritis Risk |
| View Source | June 18, 2010 | Provides Information |
| Almost three quarters of women with rheumatoid arthritis worldwide suffer pain daily |
| Almost three quarters (72%) of women with Rheumatoid Arthritis (RA) suffer pain daily, despite the fact that three quarters (75%) receive pain relief medication, according to a new study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. Furthermore the physical pain appears to affect women to such an extent that it impacts negatively on emotional and social aspects of their lives. |
| View Source | June 16, 2010 | Provides Information |
| Avila's AVL-292 demonstrates disease-modifying effects in prophylactic, therapeutic models of rheumatoid arthritis |
| Avila Therapeutics™, Inc., a biotechnology company developing targeted covalent drugs that treat diseases through protein silencing, today announced results of preclinical studies demonstrating that its clinical candidate, AVL-292, potently inhibits B cell receptor signaling, and demonstrates efficacy in a rodent model of rheumatoid arthritis. These new data were presented Saturday, June 26, 2010 at the Federation of Clinical Immunology Societies (FOCIS) 2010 annual meeting in Boston, MA. |
| View Source | June 29, 2010 | Provides Information |
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| Biologics-naive juvenile idiopathic arthritis patients have elevated risk of cancer |
| Biologics-nadve Juvenile Idiopathic Arthritis (JIA) patients may have an increased risk of cancer compared with the general Swedish population, according to research presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. Results of an additional study, which researched a small cohort of patients showed an increased frequency of cancer in those receiving the biologic etanercept, however, results were deemed not statistically significant by researchers. |
| View Source | June 17, 2010 | Provides Information |
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| Combination antibiotics effective against chlamydia-induced arthritis |
| Combination antibiotics effectively treat Chlamydia-induced reactive arthritis - a major step toward management, and possibly cure, of this disease, a federal multicenter clinical trial led by the University of South Florida College of Medicine found. |
| View Source | April 29, 2010 | Provides Information |
| Consumption of tea increases risk of Rheumatoid Arthritis in women |
| Women who drink tea have an increased risk of developing Rheumatoid Arthritis (RA) compared with those who drink none. |
| View Source | June 18, 2010 | Provides Information |
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| Expression of BCRP in RA patients may indicate higher disease activity, predict resistance to DMARDs |
| The expression of a transporter protein called the Breast Cancer Resistance Protein (BCRP) in rheumatoid arthritis (RA) patients may indicate higher disease activity and could be a barrier to the effectiveness of disease-modifying antirheumatic drugs (DMARDs), according to the results of a study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. |
| View Source | June 18, 2010 | Provides Information |
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| Finding a potential new target for treating rheumatoid arthritis |
| By enhancing the activity of immune cells that protect against runaway inflammation, researchers at NYU Langone Medical Center may have found a novel therapy for rheumatoid arthritis and other autoimmune diseases. In a new study published in the March 25, 2010 online edition of Science, the researchers reveal how treating these immune cells with an investigational drug wards off inflammation by holding a particular enzyme at bay. |
| View Source | March 25, 2010 | Provides Information |
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| Genetic basis of alopecia areata established for first time |
| A team of investigators led by Columbia University Medical Center has uncovered eight genes that underpin alopecia areata, one of the most common causes of hair loss, as reported in a paper in the July 1, 2010 issue of Nature. Since many of the genes are also implicated in other autoimmune diseases, including rheumatoid arthritis and type 1 diabetes - and treatments have already been developed that target these genes - this discovery may soon lead to new treatments for the 5.3 million Americans suffering from hair loss caused by alopecia areata. |
| View Source | June 30, 2010 | Provides Information |
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| Hope for arthritis patients in fat tissue |
| A recent discovery at the University of Arizona College of Medicine -- that adult stem cells collected from fat tissue can be converted to cells that will grow cartilage tissue -- has focused one Arizona Arthritis Center lab's research, promising new hope for osteoarthritis sufferers. |
| View Source | September 3, 2010 | Provides Information |
| Humira |
| HUMIRA is approved for reducing the signs and symptoms, inducing major clinical response, improving physical function, and helping to keep the joint damage from getting worse in adult patients with moderate to severe rheumatoid arthritis. |
| View Source | | Provides Products |
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| Knee arthritis? Flexible options can help keep you active |
| Middle-aged men and women with osteoarthritis of the knee now have more options than ever before for treatments that may allow them to remain active in the sports they love, according to a review published in the July 2010 issue of of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS). |
| View Source | July 7, 2010 | Provides Information |
| Knee Injury? Surgery Won't Cut Arthritis Risk |
| Repairing ACL or Meniscal Cartilage Knee Injury Does Not Prevent Future Knee Osteoarthritis, Study Finds |
| View Source | June 29, 2010 | Provides Information |
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| Listening Device Monitors Development of Knee Osteoarthritis |
| The BBC is reporting on new technology from University of Lancaster and University of Central Lancashire that essentially listens to knee movements to determine the progress of osteoarthritis. Specialty microphones are taped to the knees and the patient then repeatedly stands up and sits down in a chair, while computer algorithms analyze the clanging within the joints and compare that with previous sessions. |
| View Source | July 15, 2010 | Provides Information |
| Lubricating the knee cartilage after ACL repair may prevent osteoarthritis |
| An injury to the anterior cruciate ligament (ACL) is fairly common, especially among young athletes. While it can often be corrected through surgery, the injury can lead to increased risk of developing degenerative joint diseases, including osteoarthritis (OA). The problem is that fluid in the knee joint, which lubricates the cartilage, is impacted by the trauma of the injury and begins to deteriorate. A new study from Rhode Island Hospital researchers identifies options for restoring that lubrication to potentially prevent development of OA. The study is published in the August 2010 edition of the journal Arthritis & Rheumatism and is now available online ahead of print. |
| View Source | August 5, 2010 | Provides Information |
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| Majority of Ontarians suffering from rheumatoid arthritis not receiving needed speciality care |
| Nearly 60 per cent of Ontarians with rheumatoid arthritis — an autoimmune disease that causes chronic inflammation of the joints — were not seen by a specialist within a one year period to treat the debilitating disease, according to a new study. Even more concerning is that women of child-bearing age are less likely to see a specialist than women 45 or older, say researchers from St. Michael's Hospital, the Institute for Clinical and Evaluative Sciences (ICES), and Women's College Hospital. |
| View Source | July 6, 2010 | Provides Information |
| Malnutrition could cause arthritis in moose |
| 50-year-study could lead to reexamination of condition in humans |
| View Source | July 14, 2010 | Provides Information |
| Merck's SIMPONI anti-TNF therapy now reimbursed in New Brunswick, Nova Scotia and Alberta |
| First once-monthly patient-administered anti-TNF therapy now reimbursed for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis |
| View Source | August 17, 2010 | Provides Information |
| Minorities hit hardest by arthritis |
| The burden of arthritis is greater for African Americans and Hispanics, despite lower prevalence among these groups according to a Centers for Disease Control and Prevention (CDC) report published in the May issue of Preventing Chronic Disease. |
| View Source | April 15, 2010 | Provides Information |
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| New criteria by ACR for early diagnosis, treatment of rheumatoid arthritis |
| New criteria for rheumatoid arthritis (RA), published in the Annals of Rheumatic Diseases, could prevent thousands of people from developing disabling late stage disease, by redefining how RA should be classified. |
| View Source | August 13, 2010 | Provides Information |
| New Drugs for Rheumatoid Arthritis: Is a Biologic Pill on the Way? |
| The advent of a new class of drugs known as biologics has revolutionized the treatment of rheumatoid arthritis (RA). These drugs, which include Cimzia, Enbrel, Humira, Kineret, Orencia, Remicade, Rituxan, and Simponi, must be given via self-injection or intravenous infusion in the doctor’s office or hospital. They also can be expensive and are not always covered by insurance. |
| View Source | July 26, 2010 | Provides Information |
| New pathway involved in rheumatoid arthritis identified |
| Investigators from Hospital for Special Surgery have identified a pathway involved in turning off inflammation that does not work properly in people with inflammatory arthritis. The finding, reported in the April 23 issue of the journal Immunity, could lead to the development of new therapeutic approaches to treating arthritis in the future. |
| View Source | April 13, 2010 | Provides Information |
| New way of classifying rheumatoid arthritis aimed at identifying the disease earlier |
| The American College of Rheumatology today announced the release of revised classification criteria (created in collaboration with the European League Against Rheumatism) for rheumatoid arthritis, which will allow the study of treatments for RA at much earlier stages of the disease—before joint damage occurs—ultimately leading to better patient outcomes. |
| View Source | August 10, 2010 | Provides Information |
| NICE Recommends 6 Treatments For Rheumatoid Arthritis |
| The U.K.'s healthcare cost agency NICE Wednesday recommended six anti-inflammatory treatments for use in rheumatoid arthritis. |
| View Source | August 24, 2010 | Provides Information |
| NT-proBNP is a predictor of CV risk in arthritis patients taking NSAIDs |
| The role of N-terminal pro-B-type natriuretic peptide (NT-proBNP, a protein thought to be a regulator of cardiovascular function) as a robust, non-invasive predictor of cardiovascular (CV) risk in patients with arthritis taking cyclooxygenase inhibitors has been reinforced by the results of a multinational study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. |
| View Source | June 17, 2010 | Provides Information |
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| Obesity in early adulthood associated with increased risk of psoriatic arthritis |
| Among persons with psoriasis, those who reported being obese at age 18 had an increased risk of developing psoriatic arthritis, according to a report in the July 19 issue of Archives of Dermatology. |
| View Source | July 19, 2010 | Provides Information |
| Osteoporosis fractures significantly reduce quality of life |
| Women who suffer fractures from osteoporosis experience a significant reduction in their quality of life similar to or worse than that of patients with diabetes, arthritis, lung disease and other chronic illnesses. |
| View Source | August 12, 2010 | Provides Information |
| Out-of-Pocket Costs Put Arthritis Drugs Out of Reach for Some |
| People with rheumatoid arthritis whose health insurance requires them to pay a higher share of the cost are less likely to use biotech drugs than those with coverage that is more generous. High family medical bills also appear to reduce the use of these powerful but expensive medications, according to a new study in Health Services Research. |
| View Source | May 21, 2010 | Provides Information |
| Outward knee alignment increases arthritis risk, finds NIH-funded study |
| Existing arthritis worsens when poorly aligned joints bear increased stress |
| View Source | August 16, 2010 | Provides Information |
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| Partners grieve rheumatoid arthritis diagnosis as much as patients |
| Partners of patients newly diagnosed with rheumatoid arthritis (RA) are equally emotionally affected by the diagnosis and go through the same grieving process as the patients themselves, according to the results of a study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. |
| View Source | June 18, 2010 | Provides Information |
| Potential New Target for Treating Rheumatoid Arthritis |
| By enhancing the activity of immune cells that protect against runaway inflammation, researchers at NYU Langone Medical Center may have found a novel therapy for rheumatoid arthritis and other autoimmune diseases. In a new study published in the March 25, 2010 online edition of Science, the researchers reveal how treating these immune cells with an investigational drug wards off inflammation by holding a particular enzyme at bay. |
| View Source | March 26, 2010 | Provides Information |
| Potential new test for early diagnosis of osteoarthritis identified |
| Researchers at King's College London's Department of Twin Research and Genetic Epidemiology, based at St Thomas' Hospital have discovered new ways of measuring biological markers in the blood which could be used to diagnose osteoarthritis earlier. |
| View Source | April 22, 2010 | Provides Information |
| Prognosis good after Mickelson reveals arthritis |
| Phil Mickelson is being treated for arthritis that surfaced just before the U.S. Open and left him in so much pain he couldn't walk. |
| View Source | August 10, 2010 | Provides Information |
| Promoting healing by keeping skeletal stem cells 'young' |
| Scientists seeking new ways to fight maladies ranging from arthritis and osteoporosis to broken bones that won't heal have cleared a formidable hurdle, pinpointing and controlling a key molecular player to keep stem cells in a sort of extended infancy. It's a step that makes treatment with the cells in the future more likely for patients. |
| View Source | March 30, 2010 | Provides Information |
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| Rheumatoid Arthritis Incidence on the Rise in Women |
| The incidence of rheumatoid arthritis (RA) in women has risen during the period of 1995 to 2007, according to a newly published study by researchers from the Mayo Clinic. This rise in RA follows a 4-decade period of decline and study authors speculate environmental factors such as cigarette smoking, vitamin D deficiency, and lower dose synthetic estrogens in oral contraceptives may be the source of the increase. |
| View Source | May 27, 2010 | Provides Information |
| Rheumatoid arthritis signaling protein reverses Alzheimer's disease in mouse model |
| A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer's disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a new study by the University of South Florida reports. Researchers found that the protein, GM-CSF, likely stimulates the body's natural scavenger cells to attack and remove Alzheimer's amyloid deposits in the brain. |
| View Source | August 23, 2010 | Provides Information |
| Rheumatoid Arthritis: Your Options for Treatment |
| But pain, swelling, and stiffness are not the only problems for joints affected by RA. A destructive army assembles, drawn from a person’s own immune system. If not put in check, a faulty immune system can attack cartilage and bone within the joint as well as other healthy tissues in the body. |
| View Source | July 26, 2010 | Provides Information |
| 'Rotten eggs' gas and inflammation in arthritic joints |
| Hydrogen sulfide (H2S) is a gas more commonly associated with the smell of 'rotten eggs' and blocked drains. However, it has now been shown to be present naturally in our bodies and reside in knee joint synovial fluid, the protective fluid found in the cavities of joints that reduces friction between the cartilage of joints during movement. Synovial fluid H2S may play a role in reducing inflammation in joints. |
| View Source | August 20, 2010 | Provides Information |
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| Scientists discovers body's own molecular protection against arthritis |
| An international team of scientists from The Scripps Research Institute in California and the National Research Institute for Child Health and Development in Japan has discovered that a natural molecule in the body counters the progression of osteoarthritis. The findings could one day lead to new therapies for some common diseases of aging. |
| View Source | May 18, 2010 | Provides Information |
| Sex lives of patients are negatively affected by rheumatoid arthritis and SLE |
| Systemic Lupus Erythematosus (SLE) patients from Brazil and Rheumatoid Arthritis (RA) patients from France report that their rheumatic conditions negatively affect their emotional relationships and sex lives, according to research presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. Furthermore, findings of the French study specifically revealed a strong correlation between RA disease severity and impact on sex life. |
| View Source | June 18, 2010 | Provides Information |
| Shoes: A treatment for osteoarthritis in the knees? |
| Flip-flops and sneakers with flexible soles are easier on the knees than clogs or even special walking shoes, a study by Rush University Medical Center has found. And that's important, because loading on the knee joints is a key factor in the development of osteoarthritis. |
| View Source | March 24, 2010 | Provides Information |
| Shoulder arthritis? What patients need to know before treatment |
| The American Academy of Orthopaedic Surgeons (AAOS) has approved and released an evidence-based clinical practice guideline on "The Treatment of Glenohumeral Joint Osteoarthritis." This major joint in the shoulder — the ball and socket joint — is sometimes affected by osteoarthritis, causing pain, loss of function, and reduced quality of life. |
| View Source | July 15, 2010 | Provides Information |
| Sodium MRI gives new insights into detecting osteoarthritis, researchers find |
| Researchers at New York University have developed an innovative way to look at the development of osteoarthritis in the knee joint—one that relies on the examination of sodium ions in cartilage. Their work, which appears in the Journal of Magnetic Resonance, may provide a non-invasive method to diagnose osteoarthritis in its very early stages. |
| View Source | August 27, 2010 | Provides Information |
| Study: Alcohol Helps Rheumatoid Arthritis Symptoms |
| But Expert Calls Findings 'Weak Science' |
| View Source | July 28, 2010 | Provides Information |
| Study finds link between early nutrition and arthritis in people and moose |
| It's seen as a sign of getting old, but scientists have discovered that arthritis is not just a human problem as a study lasting 50 years reveals how moose suffer from an identical form of the condition. The research, published in Ecology Letters, also casts new light on how malnutrition early in life can lead to the disorder in both moose and humans. |
| View Source | July 7, 2010 | Provides Information |
| Study links rheumatoid arthritis to vitamin D deficiency |
| Women living in the northeastern United States are more likely to develop rheumatoid arthritis (RA), suggesting a link between the autoimmune disease and vitamin D deficiency. |
| View Source | April 7, 2010 | Provides Information |
| Study finds sham acupuncture superior to traditional Chinese acupuncture in osteoarthritis treatment |
| Researchers from MD Anderson Cancer Center determined patients with osteoarthritis (OA) of the knee who are treated with traditional Chinese acupuncture (TCA) do not experience any more benefit than those receiving sham acupuncture (placebo). The team did find that the communication style of the acupuncturist could have a significant effect on pain reduction and satisfaction in patients. Full findings are now online and will publish in the September print issue of Arthritis Care & Research, a journal of the American College of Rheumatology. |
| View Source | August 17, 2010 | Provides Information |
| Subchondral Bone Changes: Cartilage Loss Plays a Role in Development of Osteoarthritis, Study Says |
| A recent study determined that bone area predicted the development of medial (inner side) and lateral (outer side) knee cartilage damage and loss of medial cartilage volume. Subchondral bone mineral density (BMD) was associated with medial defect development but not cartilage loss. Researchers believe subchondral bone changes and loss of cartilage contribute to the development of osteoarthritis (OA). |
| View Source | June 28, 2010 | Provides Information |
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| Tai Chi for Arthritis Relief |
| Gentle movements of the ancient Chinese exercise tai chi are one of many alternatives to help elderly people find pain relief. |
| View Source | July 20, 2010 | Provides Information |
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| Unequal leg length tied to osteoarthritis |
| A new study shows that arthritis in the knee is linked to the common trait of having one leg that is longer than the other. Whether or not leg length differential is a direct cause of osteoarthritis is not clear, but the findings may allow people to take preventive measures before the onset of the chronic and painful condition. |
| View Source | March 31, 2010 | Provides Information |
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| VBL presents positive preclinical data on VB-201 for rheumatoid arthritis at EULAR |
| VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced preclinical data demonstrating that VB-201 possesses anti-inflammatory properties and effectively reduced the symptoms of arthritis in experimental models. These results were presented today at the European League Against Rheumatism (EULAR) Annual European Congress of Rheumatology, by Niva Yacov, M.Sc., project manager at VBL. |
| View Source | June 17, 2010 | Provides Information |
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| Worse mental health associated with worse pain in osteoarthritis: study |
| How much pain osteoarthritis sufferers feel is directly related to their mental health, a new study by researchers at UC Davis School of Medicine has found. In the study, people with better mental health felt less pain, and people with worse mental health felt more. |
| View Source | July 30, 2010 | Provides Information |