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307 Health - Diabetes Resources
1 in 10 Chinese adults are diabetics, study finds
Nation now home to the most cases worldwide — 92 million
View SourceMarch 24, 2010Provides Information
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A 1-2 punch: Embryonic cell and adult pig islet transplants cure diabetes in rats
In a step toward curing diabetes in humans, scientists at Washington University School of Medicine in St. Louis have alleviated the disease in rats using transplants from both embryonic and adult pigs.
View SourceJune 29, 2010Provides Information
A bittersweet warning for women with gestational diabetes
A common test to diagnose gestational diabetes -- a temporary condition which can harm both mother and child if left untreated -- also has predictive power for Type II adult-onset diabetes, a new Tel Aviv University study finds.
View SourceJuly 7, 2010Provides Information
A1c Test Identifies Diabetes, Heart Risk
Study Shows Non-Fasting Diabetes Test More Accurate Than Blood Glucose Test
View SourceMarch 3, 2010Provides Information
ACCORD eye study finds 2 therapies slow diabetic eye disease progression
In high-risk adults with type 2 diabetes, researchers have found that two therapies may slow the progression of diabetic retinopathy, an eye disease that is the leading cause of vision loss in working-age Americans.
View SourceJune 29, 2010Provides Information
Adults with newly diagnosed diabetes at risk of liver disease
Adults with newly diagnosed diabetes are at higher long-term risk of serious liver disease, including cirrhosis and liver failure, according to a research article published in CMAJ (Canadian Medical Association Journal).
View SourceJune 21, 2010Provides Information
AFREZZA provides long-term glucose control in Type 2 diabetics: Study
AFREZZATM™ Inhalation Powder, a well-tolerated, investigational ultra rapid acting mealtime insulin, as part of a diabetes treatment regimen, provides long-term glucose control comparable to usual insulin therapy but with a significantly reduced incidence of hypoglycemia and less weight gain in patients with Type 2 diabetes.
View SourceJune 29, 2010Provides Information
Aggressive control of cardiac risk factors might not benefit all patients with diabetes
A mathematical model suggests that aggressively pursuing low blood pressure and cholesterol levels may not benefit, and could even harm, some patients with diabetes, according to a report in the June 28 issue of Archives of Internal Medicine.
View SourceJune 28, 2010Provides Information
Aiming for Near-Normal Blood Sugar Did Not Delay Combined Risk of Diabetic Damage for People With Long-standing Diabetes, NIH-Sponsored Trial Finds
Some Signs of Damage to Kidneys, Eyes, Nerves Delayed
View SourceJune 29, 2010Provides Information
Alere Health achieves NCQA Accreditation
Alere Health, LLC, the health management services business of Alere Inc., announced today that it has achieved the National Committee for Quality Assurance (NCQA) Patient and Practitioner Oriented Full Accreditation for its Disease Management program, encompassing services for asthma, chronic obstructive pulmonary disease, diabetes, musculoskeletal pain, coronary artery disease, heart failure, depression and high-risk pregnancies.
View SourceAugust 30, 2010Provides Information
Alpha-Lipoic Acid
Alpha-lipoic acid is an antioxidant that's in many foods, and it's made naturally in our bodies. For many years, high doses of alpha-lipoic acid supplements have been used in parts of Europe for certain types of nerve damage. Studies suggest that they might also help with type 2 diabetes.
View SourceApril 7, 2010Provides Information
An Implantable Glucose Sensor Could Help Diabetics Stay Healthy
Nurses usually pluck splinters from people’s flesh, not put them in. But a new rice-size implantable glucose sensor that monitors blood sugar all day might mean less pain for diabetics.
View SourceMarch 3, 2010Provides Information
Antibiotic may reduce stroke risk and injury in diabetics
A daily dose of an old antibiotic may help diabetics avoid a stroke or at least minimize its damage, Medical College of Georgia researchers report.
View SourceAugust 23, 2010Provides Information
Arcion reports top-line results from ARC-4558 Phase 2b clinical trial for painful diabetic neuropathy
Arcion Therapeutics, a venture backed clinical stage biotechnology company developing topical therapies for chronic pain, today announced top-line results from a successful Phase 2b double-blind, randomized, placebo-controlled clinical trial of its lead topical pain candidate, ARC-4558, in adult patients with painful diabetic neuropathy (PDN). Arcion recently held an End of Phase 2 meeting with the United States Food and Drug Administration (FDA) and the ARC-4558 program is now poised to enter Phase 3 studies. ARC-4558 is a 0.1% gel formulation of clonidine hydrochloride for topical administration.
View SourceJuly 20, 2010Provides Information
'Artificial pancreas' for diabetes is testing well
Scientists are getting closer to offering an "artificial pancreas" to children and adults with type 1 diabetes that will help better control the swings of blood glucose that come with the disease.
View SourceJune 28, 2010Provides Information
Artificial Pancreas Shows Promise in 11 Patients with Type 1 Diabetes
Researchers at MGH and Boston University have reported that an "artificial pancreas" has worked in 11 patients enrolled in a study sponsored by the Juvenile Diabetes Research Foundation.
View SourceApril 16, 2010Provides Information
Aspirin Recommendations Changed for Many Younger Diabetic Patients
Experts are now recommending that low-dose aspirin therapy to prevent heart attacks be used somewhat more conservatively -- that men younger than 50 and women younger than 60, who have diabetes but no other major risk factors, probably not use aspirin.
View SourceJune 2, 2010Provides Information
AstraZeneca, NIDDK partnership to support Drug-Induced Liver Injury Network
A new public-private partnership between AstraZeneca and NIH's National Institute of Diabetes and Digestive and Kidney Diseases will focus on supporting the work of the Drug-Induced Liver Injury Network.
View SourceMay 28, 2010Provides Information
Avandia and diabetes: Was revolution worth the risks?
A decade after critics first accused the Food and Drug Administration of downplaying side effects from Avandia, the agency says it will reveal on Friday the data it is reviewing ahead of an advisory panel meeting about the safety of the popular diabetes drug.
View SourceJuly 8, 2010Provides Information
Avandia: Less Risky in Younger, Healthier Patients?
Study Finds Avandia No Riskier Than Actos, Unlike 4 Other Studies
View SourceAugust 24, 2010Provides Information
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B vitamin therapy linked with decline in kidney function for some kidney disease patients
Patients with diabetic nephropathy (kidney disease caused by diabetes) who received high dose B-vitamin therapy experienced a more rapid decline in kidney function and had a higher rate of heart attack and stroke than patients who received placebo, according to a study in the April 28 issue of JAMA.
View SourceApril 27, 2010Provides Information
Bad Hot Flashes? Try Dropping a Few Pounds
Overweight women who suffer from bothersome hot flashes may find some relief by losing some weight, hints a new study published today.
View SourceJuly 13, 2010Provides Information
Bad night's sleep can hamper body's insulin use
Study suggests link between insomnia and rise in diabetes
View SourceMay 5, 2010Provides Information
Bariatric surgery in diabetic adults improves insulin sensitivity better than diet
Gastric bypass surgery improves Type 2 diabetes by other mechanisms in addition to weight loss and does so better than a low-calorie diet despite achieving equal weight loss, a new study finds. The results will be presented Monday at The Endocrine Society's 92nd Annual Meeting in San Diego.
View SourceJune 21, 2010Provides Information
Big first trimester weight gain ups diabetes risk
Packing on too many pounds too quickly hikes chance of developing disease
View SourceMarch 11, 2010Provides Information
Biochemist proposes worldwide policy change to step up daily vitamin D intake
Anthony Norman, a leading international expert in vitamin D, proposes worldwide policy changes regarding people's vitamin D daily intake amount in order to maximize the vitamin's contribution to reducing the frequency of many diseases, including childhood rickets, adult osteomalacia, cancer, autoimmune type-1 diabetes, hypertension, cardiovascular disease, obesity and muscle weakness.
View SourceAugust 9, 2010Provides Information
Biodel reports preclinical test results of BIOD620 glucose-regulated or "smart" basal insulin product candidate
Biodel Inc. today reported results of preclinical tests which demonstrated the potential of the company's glucose-regulated or "smart" basal insulin product candidate, BIOD620, to release insulin proportionally in response to changing glucose conditions. In an oral presentation today at the 37th Annual Meeting and Exposition of the Controlled Release Society in Portland, Oregon, Nandini Kashyap, director of novel drug delivery at Biodel, described results of in vitro and in vivo studies with diabetic pigs which compared the use of BIOD620 to Lantus® (insulin glargine).
View SourceJuly 13, 2010Provides Information
Biodel seeks FDA marketing approval for VIAject
Biodel Inc. announced today that the U.S. Food and Drug Administration has accepted for review the company’s new drug application (NDA) seeking approval to market VIAject® for the treatment of diabetes.
View SourceMarch 1, 2010Provides Information
Biologists find a way to lower tumor risk in stem cell therapies
One of the characteristics of embryonic stem cells is their ability to form unusual tumors called teratomas. These tumors, which contain a mixture of cells from a variety of tissues and organs of the body, are typically benign. But they present a major obstacle to the development of human embryonic stem cell therapies that seek to treat a variety of human ailments such as Parkinson's, diabetes, genetic blood disorders and spinal cord injuries.
View SourceJuly 8, 2010Provides Information
Biologists identify a new clue into cellular aging
The ability to combat some age-related diseases, such as cancer and diabetes, may rest with scientists unlocking clues about the molecular and cellular processes governing aging. The underlying theory is that if the healthy portion of an individual's life span can be extended, it may delay the onset of certain age-related diseases. In the search to understand these molecular processes, researchers at the University of Massachusetts Medical School have uncovered an important new DAF-16 isoform - DAF-16d/f - that collaborates with other DAF-16 protein isoforms to regulate longevity.
View SourceJuly 7, 2010Provides Information
Block by block: A campaign to combat diabetes
It started with a simple medical survey in the Humboldt Park neighborhood on Chicago's near Northwest side whose results were reported in the Journal of Epidemiology in 2006.
View SourceApril 19, 2010Provides Information
Boar's Head promotes healthy lifestyle options and helps champion the cause of diabetes prevention
Boar's Head, a leader in developing fine deli products that respond to consumers' health and wellness concerns, announces an initiative to reach the growing number of Americans now following a gluten free way of life. "Gluten Free with Boar's Head," is reaching out to gluten free followers with news that Boar's Head meats, cheeses and condiments are, and always have been, gluten free.
View SourceMarch 5, 2010Provides Information
Body's anticipation of a meal can be a diabetes risk factor
Alterations in our response to the taste or smell of food may be another culprit responsible for Type 2 diabetes, according to scientists at Duke University Medical Center who have identified the specific mechanism in human specimens and in mice.
View SourceMarch 11, 2010Provides Information
Bone marrow cells produce nerve growth factor and promote angiogenesis around transplanted islets
Islet transplantation is a promising treatment for type 1 diabetes mellitus. The promotion of angiogenesis is an important endeavor to prevent islet graft failure. Endothelial precursor cells (EPCs), a heterogeneous group originating in the hematopoietic compartment of bone marrow, have an important role in the angiogenesis of adult tissues.
View SourceApril 1, 2010Provides Information
Brain Changes in Obese Kids With Diabetes Hinder Learning
Exercise, Weight Loss May Lessen Brain Effects, Researchers Say
View SourceAugust 3, 2010Provides Information
Brain Surgery to Treat Type 2 Diabetes?
New research suggests a type of brain surgery may decrease the onset and progression of type 2 diabetes, the Pittsburgh Post Gazette reported.
View SourceAugust 13, 2010Provides Information
Breakdown of bone keeps blood sugar in check, new study finds
Researchers led by Columbia University Medical Center have discovered that the skeleton plays an important role in regulating blood sugar and have further illuminated how bone controls this process. The finding, published in Cell, is important because it may lead to more targeted drugs for type 2 diabetes.
View SourceJuly 22, 2010Provides Information
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Cancer and diabetes: One discovery is affecting two areas of research
Killing two birds with one stone. Sometimes, research results open up unexpected possibilities. This was what happened in the experiments of Chang Xian Zhang, a senior research scientist at Inserm, and his collaborators in the Laboratoire Géeetique Moleculaire, Signalisation et Cancer (CNRS, France). Their recent work on pancreatic endocrine tumours is also proving beneficial to research on the development of diabetes treatments.
View SourceApril 30, 2010Provides Information
Carrot-and-stick health plans reshape care
Some illnesses completely covered, but certain treatments have hefty fees
View SourceMarch 17, 2010Provides Information
Cashew seed extract an effective anti-diabetic
Cashew seed extract shows promise as an effective anti-diabetic, according to a new study from the University of Montreal (Canada) and the Université de Yaoundé (Cameroun). Published in the journal Molecular Nutrition & Food Research, the investigation analyzed the reputed health benefits of cashew tree products on diabetes, notably whether cashew extracts could improve the body's response to its own insulin.
View SourceJuly 14, 2010Provides Information
Catabasis Pharmaceuticals to advance program targeting type 2 diabetes with $39.6 million Series A financing
Catabasis Pharmaceuticals, a biopharmaceutical company developing novel therapeutics for the treatment of inflammatory and metabolic diseases, today announced it has completed a $39.6 million Series A financing led by SV Life Sciences, Clarus Ventures, and MedImmune Ventures. Also participating in the round is Advanced Technology Ventures. Proceeds from the financing will be used to advance Catabasis' lead program targeting type 2 diabetes, and to further the development of the company's proprietary platform technology in additional inflammatory and metabolic diseases.
View SourceApril 21, 2010Provides Information
Cellonis' stem cells diabetes treatment helps reconstruct natural insulin production
Cellonis, a Beijing and HK-based biotech company, with its new personalized diabetes treatment concept has demonstrated an amazing improvement in their treated patients' conditions. The ongoing clinical study shows the treatment's best case could reconstruct a patient's natural insulin production and even reverse later complications like kidney failure. Treated patients may have the chance to return to the normal activities non-diabetes sufferers take for granted.
View SourceJune 24, 2010Provides Information
Children's gut bacteria linked to type 1 diabetes
University of Florida researchers have found that the variety of bacteria in a child’s digestive tract is strongly linked to whether that child develops type 1 diabetes. The connection could eventually give doctors an early test for the condition and a new way to treat the disease that afflicts more than 3 million Americans.
View SourceJuly 13, 2010Provides Information
China Becomes World's New Diabetes Capital
China now has more people with diabetes than any other country, a new report shows, making it clear that the nation's soaring economic growth is taking a toll on public health.
View SourceMarch 25, 2010Provides Information
Click and Pump Insulin Delivery Device from Calibra Medical
Calibra Medical out of Redwood City, CA has received FDA approval to market its Finesse insulin patch-pen. Earlier this year, Bernard Farrell over at his Diabetes Technology Blog had a chance to get a closer look at the fully mechanical device.
View SourceJuly 26, 2010Provides Information
Company decision to pull diabetes drug could add GBP9 million to NHS drugs bill
Drug company Novo Nordisk's decision to pull its Mixtard 30 insulin drug from the UK could add GBP9 million to the NHS drugs bill in England alone, says an editorial in the Drug and Therapeutics Bulletin (DTB).
View SourceAugust 3, 2010Provides Information
Computers analyze environmental factors in diabetes
Like many complex diseases, diabetes results from the interplay of genetic and environmental factors. To examine genetic risk factors, scientists pore over the human genome sequence. Environmental factors have been trickier to pin down because there is no way to evaluate them comprehensively.
View SourceMay 20, 2010Provides Information
Computers can effectively detect diabetes-related eye problems
People with diabetes have an increased risk of blindness, yet nearly half of the approximately 23 million Americans with diabetes do not get an annual eye exam to detect possible problems.
View SourceMay 13, 2010Provides Information
Considering diabetes treatment, experts say one size does not fit all
Patients with type 2 diabetes are generally treated similarly despite the fact that they may have underlying differences that could affect their therapeutic response. Seeking to address this critical health issue, an international multidisciplinary group of experts just issued recommendations for individualized treatment in a consensus statement to be published in the April 2010 issue of the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). The group consisted of experts in diabetes epidemiology, physiology, genetics, clinical trials and clinical care.
View SourceApril 5, 2010Provides Information
CoreObjects receives PMI Excellence Award for developing HbA1c Blood Sugar Analysis device
CoreObjects is proud to announce the achievement of the Project Management Institutes (PMI) "Excellence Award" for their role in helping launch a product that enhances the quality of life for patients suffering from diabetes. CoreObjects and their customer Piramal Healthcare shared PMIs "Project Management Excellence Award" for their management of the concept and development of the HbA1c Blood Sugar Analysis device, designed for diabetes patients.
View SourceMarch 12, 2010Provides Information
Chronic Insomnia May Cut a Life Short
People Who Struggle to Sleep Appear to Be at Higher Risk for Early Death, Researchers Say
View SourceJune 7, 2010Provides Information
Consistent and successful islet isolations offer diabetes hope
A team of researchers from several collaborating Baylor University research centers and from Japan's Okayama Graduate School of Medicine have found a way to more consistently isolate pancreatic islet cells from brain dead donors using ductal injection (DI), a process that immediately cools donor islet cells at the injection site. The more successful islet isolation process resulted in the three type 1-diabetes patients, who received islet cell transplants, becoming insulin independent.
View SourceJune 3, 2010Provides Information
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Death rates from type 1 diabetes steadily improving
Advances in treatment and care have reduced overall death rates from type 1 diabetes, with women and African-Americans having higher risks of mortality, according to a University of Pittsburgh Graduate School of Public Health study being presented at the 70th Scientific Sessions of the American Diabetes Association.
View SourceJune 28, 2010Provides Information
Defects in immune system enzyme may increase risk of autoimmune disorders
A multi-institutional research team has found that rare variants in the gene coding an enzyme that controls the activity of a key immune cell occur more frequently in individuals with autoimmune disorders like rheumatoid arthritis and type 1 diabetes. Their report, which will appear in the journal Nature and is receiving early online release, identifies a pathway that could be a therapeutic target and may present a model for future investigations of the role of rare gene variants in common disorders.
View SourceJune 16, 2010Provides Information
Definitive diabetes indicator deceptively high in African-American children
Researchers at LSU Health Sciences Center New Orleans and Children's Hospital of New Orleans have found that there is a major difference in the hemoglobin A1c (HbA1c) response to blood glucose between African-American and Caucasian children with diabetes. HbA1c is the main test used to monitor diabetes and guide treatment decisions. African-American children test significantly higher than Caucasians who have similar average blood glucose levels. The research may explain why African Americans are at increased risk of diabetes complications.
View SourceMay 4, 2010Provides Information
Diabetes 9 to 5: Tips to Help You Manage Your Diabetes at Work
Controlling symptoms is critical to controlling your diabetes. Here's how experts say you can do the job while on the job.
View SourceAugust 23, 2010Provides Information
Diabetes can cause a sugar coating that smothers body's immune defences
Research led by the Warwick Medical School at the University of Warwick has found that unhealthy glucose levels in patients with diabetes can cause significantly more problems for the body than just the well-known symptoms of the disease such as kidney damage and circulation problems. The raised glucose can also form what can be described as a sugar coating that can effectively smother and block the mechanisms our bodies use to detect and fight bacterial and fungal infections.
View SourceAugust 23, 2010Provides Information
Diabetes care devices market in BRIC to reach $570.56M in 2014 at CAGR of 17.24%: M&M
According to the new market research report, "Diabetes care devices market in Brazil, Russia, India, China (BRIC)" published by MarketsandMarkets, the diabetes care devices market in BRIC was approximately $257.55 million in 2009 and is expected to reach $570.56 million in 2014 at an estimated CAGR of 17.24% from 2009 to 2014.
View SourceJune 15, 2010Provides Information
Diabetes Caught Early Saves Lives, Money
Screening for Type 2 Diabetes Starting at Age 30-45 Reduces Deaths, Costly Health Complications
View SourceMarch 29, 2010Provides Information
Diabetes doubles risk of heart attack and strokes
Having diabetes doubles the risk of developing a wide range of blood vessel diseases, including heart attacks and different types of stroke, researchers in Cambridge have found.
View SourceJune 25, 2010Provides Information
Diabetes Drug Avandia as Safe as Actos: Study
GlaxoSmithKline's diabetes drug Avandia was no riskier to the heart than a rival, U.S. researchers said on Tuesday, a finding that contradicts earlier studies and adds new fodder to the roiling debate over the drug's safety.
View SourceAugust 25, 2010Provides Information
Diabetes drug risks reported ahead of FDA hearing
A new study led by a federal drug safety expert ties the controversial diabetes drug Avandia to a higher risk of heart problems, strokes and deaths in older adults, and says it is more dangerous than a rival drug, Actos.
View SourceJune 28, 2010Provides Information
Diabetes' link to eating disorders explored
Diabetics, under the gun to better manage their disease by controlling their food intake and weight, may find themselves in the sticky wicket of needing treatment that makes them hungry, researchers said.
View SourceMarch 11, 2010Provides Information
Diabetes monitoring device benefits man and man's best friend
The treatment of diabetes was revolutionized in 1922 when insulin was isolated from dogs. Since then, significant advances in human medicine have made diabetes more manageable for patients. Now, human medicine has returned the favor and used these advances to help dogs with diabetes. A University of Missouri researcher is using a continuous glucose monitoring device - commonly used in humans with diabetes - to help treat dogs and other animals. The device, which provides a detailed glucose picture of an animal over several days, will help pet owners manage their pets' diabetes.
View SourceJuly 23, 2010Provides Information
Diabetes Nerve Pain May Worsen at Night
People With Diabetic Peripheral Neuropathy Report Worst Pain at 11 p.m., Study Finds
View SourceMay 7, 2010Provides Information
Diabetes now tops Vietnam vets' health claims
Exposure to Agent Orange cited as cause for disability that exceeds PTSD
View SourceAugust 30, 2010Provides Information
Diabetes or not, dietary habits of Aftrican-Americans are similar
Researchers looking for differences in eating habits of African Americans based on whether or not they had Type 2 diabetes uncovered an unexpected result: No matter what the blood sugar level was, the dietary intakes were pretty much the same.
View SourceAugust 5, 2010Provides Information
Diabetes patients admitted for acute exacerbations of COPD have longer hospital stay
A new study in the journal Respirology reveals that patients with diabetes who are hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD) experience longer time in the hospital and are also at an increased risk of death, compared to those without diabetes.
View SourceJune 21, 2010Provides Information
Diabetes risk in children increases risk for weak bones
Children at risk for diabetes before they reach puberty also appear to be at risk for weak bones, Medical College of Georgia researchers report.
View SourceAugust 16, 2010Provides Information
Diabetes shouldn't deter young athletes: study
A new study led by York University researchers finds that young athletes with Type 1 diabetes may experience a marked decrease in performance as a result of their blood sugar levels.
View SourceJuly 15, 2010Provides Information
Diabetes Symptoms to Never Ignore
Watch out for signs of heart disease, uncontrolled blood sugar, infection, eye problems, and more.
View SourceJune 3, 2010Provides Information
Diabetes: Treating Wounds and Injuries
No matter how small or superficial a wound is, you should not ignore it if you have diabetes, says Daniel Cohen, DPM, a podiatrist with Medical Associates of Brevard in Brevard County, Fla. If you stub your toe, get a blister from tight shoes, or nick your chin while shaving, you probably give it little thought. But if you have diabetes, you should seek proper treatment.
View Source Provides Information
Diabetic factors associated with gastrointestinal symptoms
There are several papers which report the association of GI symptoms with diabetes. Epidemiological data regarding the association of GI symptoms with diabetes are, however, inconsistent, and the reported frequency of upper and lower GI symptoms varies among different ethnic groups/populations.
View SourceApril 12, 2010Provides Information
Diabetics at risk: Nova Scotia limits pharmacare coverage of blood glucose test strips
The Nova Scotia government's decision to limit Pharmacare coverage of blood glucose test strips for some diabetes patients places a significant financial and health burden on these Nova Scotians and violates the fundamental principle that patients and their healthcare professionals should be able to determine how to manage treatment.
View SourceMarch 3, 2010Provides Information
Diabetics eye obesity surgery to tame blood sugar
For nearly a decade, Cristina Iaboni tried to tame her diabetes the usual way, through daily shots of insulin and other medicine.
View SourceJuly 7, 2010Provides Information
Diazyme HbA1c Point of Care Assay Receives FDA Clearance
Diazyme Laboratories (San Diego, CA) has received FDA clearance for its SMART HbA1c Assay on the SMART Point of Care System for diabetes monitoring. HbA1c or glycated hemoglobin is, of course, a measure of long-time blood glucose control, with its level proportional to average blood glucose concentration over the previous one to three months.
View SourceMay 10, 2010Provides Information
Difficulty Trusting and Reaching out to Others May Shorten Diabetes Patients' Lives
Mistrust can exact a high toll. Being overly cautious or dismissive in relating to people, researchers are learning, may shorten the lives of people with diabetes.
View SourceMarch 17, 2010Provides Information
Disabilities strike the middle-aged: Sedentary lifestyle, obesity among major reasons
Lucille Morris was in her mid-50s when she was diagnosed with Type 2 diabetes. Not long after, she began experiencing pain and numbness in her feet from neuropathy. Walking felt painful and wobbly.
View SourceJune 4, 2010Provides Information
Discovery advances control of starch digestion
Controlling diet-induced degenerative disorders such as Type II Diabetes and obesity could be as easy as sprinkling a dietary supplement on your food in the future.
View SourceJune 4, 2010Provides Information
Discovery points to new approach for diabetes therapy
Nutrition experts at Oregon State University have essentially "cured" laboratory mice of mild, diet-induced diabetes by stimulating the production of a particular enzyme.
View SourceJuly 12, 2010Provides Information
Discovery prompts new theory on cause of autoimmune diseases
The recent discovery of a protein fragment capable of causing diabetes in mice has spurred researchers at National Jewish Health and the University of Colorado Denver to propose a new hypothesis about the cause of diabetes and autoimmunity in general. In the April 23, 2010, issue of Immunity, Drs. Brian Stadinski, John Kappler and George Eisenbarth propose that the unusual and rare presentation of protein fragments (peptides) to the immune system allows autoreactive T cells to escape the thymus and trigger autoimmune disease. The findings could lead to a new strategy for preventing type 1 diabetes
View SourceMay 3, 2010Provides Information
Disruption of circadian rhythm could lead to diabetes
Disruption of two genes that control circadian rhythms can lead to diabetes, a researcher at UT Southwestern Medical Center has found in an animal study.
View SourceJuly 13, 2010Provides Information
Drug Combo May Prevent Diabetes
Study Shows Low Doses of Avanida, Metformin Ward Off Diabetes for at-Risk Patients
View SourceJune 2, 2010Provides Information
Drug Reverses Diabetes-Related Vision Loss
Lucentis Combined With Laser Better Than Laser Alone, Government Study Finds
View SourceApril 28, 2010Provides Information
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Eating Processed Meats, but Not Unprocessed Red Meats, May Raise Risk of Heart Disease and Diabetes, Study Finds
In a new study, researchers from the Harvard School of Public Health (HSPH) have found that eating processed meat, such as bacon, sausage or processed deli meats, was associated with a 42% higher risk of heart disease and a 19% higher risk of type 2 diabetes. In contrast, the researchers did not find any higher risk of heart disease or diabetes among individuals eating unprocessed red meat, such as from beef, pork, or lamb. This work is the first systematic review and meta-analysis of the worldwide evidence for how eating unprocessed red meat and processed meat relates to risk of cardiovascular diseases and diabetes.
View SourceMay 18, 2010Provides Information
Embryonic Cell and Adult Pig Islet Transplants Cure Diabetes in Rats
In a step toward curing diabetes in humans, scientists at Washington University School of Medicine in St. Louis have alleviated the disease in rats using transplants from both embryonic and adult pigs.
View SourceJune 29, 2010Provides Information
Ethnic differences in precursors of type 2 diabetes apparent at an early age
A study published in PLoS Medicine this week finds that precursors of higher risk of diabetes in South Asian and African-Caribbean adults in the UK are increased in healthy children from these ethnic groups.
View SourceApril 20, 2010Provides Information
EU and U.S. weigh fate of Glaxo's Avandia
GlaxoSmithKline Plc's diabetes pill Avandia came under intense scrutiny on both sides of the Atlantic on Friday, leaving the drug's future uncertain as its maker battles a wave of lawsuits.
View SourceJuly 9, 2010Provides Information
European market for continuous glucose monitoring to reach $52M in 2016
The continuous glucose monitoring (CGM) market is in its development stage. The primary factor leading to the growth of the (CGM) market in Europe is the need for an easy-to-use and patient-friendly glucose-monitoring device. The traditional method of monitoring glucose was difficult and inconvenient for patients. The CGM method is not only hassle-free, but also gives a better diagnosis of diabetes.
View SourceJune 16, 2010Provides Information
Exercise counters negative effects of weight regain, researchers find
With the obesity rate rising for American adults and children, health concerns such as diabetes and cardiovascular disease are a frequent reality. Although obesity itself is a major risk factor for disease, most of the threat may be associated with a cluster of risk factors called the metabolic syndrome (MetS). Losing weight can improve health and reduce these risk factors, but many people have difficulty keeping the weight off. Now, University of Missouri researchers have found that exercising during weight regain can maintain improvements in metabolic health and disease risk.
View SourceMarch 2, 2010Provides Information
Experimental cure for Type 1 diabetes
Researchers have developed an experimental cure for Type 1 diabetes, a disease that affects about one in every 400 to 600 children and adolescents. They will present their results in a mouse model of Type 1 diabetes on Sunday at The Endocrine Society's 92nd Annual Meeting in San Diego.
View SourceJune 21, 2010Provides Information
Experts call for further research into the relationship between insulin therapy and cancer
The benefits of using insulin to treat diabetes far outweigh the risks, but a review just published online by IJCP, the International Journal of Clinical Practice, suggests that commonly used diabetes therapies may differ from each other when it comes to their influence on cancer risk.
View SourceMarch 2, 2010Provides Information
Eye Damage Common in Older Diabetes Patients
CDC Estimates That More Than a Fourth of Older Diabetes Patients Have Diabetic Retinopathy
View SourceAugust 10, 2010Provides Information
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Fat Cells Play Key Role in Development of Type 2 Diabetes
Cellular changes in fat tissue -- not the immune system -- lead to the "hyperinflammation" characteristic of obesity-related glucose intolerance and type 2 diabetes, according to new research from the University of Cincinnati (UC).
View SourceJuly 6, 2010Provides Information
Fat Distribution Plays a Role in Weight Loss Success in Patients at Risk of Diabetes
Why is it that some people lose weight and body fat when they exercise and eat less and others don't? German researchers say MRI and magnetic resonance (MR) spectroscopy can provide the answer -- and help predict who will benefit from lifestyle changes. Results of the study are published online and will appear in the November issue of the journal Radiology.
View SourceAugust 26, 2010Provides Information
FDA approves trial for type 1 diabetes treatment
The U.S. Food & Drug Administration has granted Investigational New Drug regulatory clearance to initiate a Phase I/II clinical trial evaluating Alpha-1 Antitrypsin in type 1 diabetics, based on research by Dr. Eli Lewis of Israel's Ben-Gurion University of the Negev.
View SourceJune 29, 2010Provides Information
FDA Clears Abbott's New FreeStyle Lite Diabetes Test Strips
Abbott Diabetes Care has announced 510(k) clearance of their new FreeStyle Lite blood glucose test strips, designed for use with the company's existing FreeStyle Lite monitors. The strips improve the safety of at-home blood glucose monitoring by eliminating the possibility of interference from non-glucose sugars in readings, which according to the FDA has resulted in hundreds of cases of insulin overdose due to erroneously high glucose readings.
View SourceMay 25, 2010Provides Information
FDA issues hold on much-debated Avandia study
Federal health officials are barring new patients from enrolling in a safety study of GlaxoSmithKline's controversial diabetes pill Avandia, a week after a panel of experts ruled that the drug increases heart risks.
View SourceJuly 21, 2010Provides Information
FDA OKs new type of diabetes-monitoring system
In development for more than five years, WellDoc's DiabetesManager System has just received the U.S. Food and Drug Administration's 510(k) clearance to be marketed to health care providers and adult patients with type 2 diabetes, the company announced.
View SourceAugust 3, 2010Provides Information
FDA review spotlights heart risk of diabetes pill
A review by federal health scientists reinforces potential ties between the diabetes pill Avandia and heart attack and death, opening the door for government action, including a possible withdrawal of the once blockbuster drug.
View SourceJuly 9, 2010Provides Information
Feet first: Molecular imaging helps diagnose diabetic foot infection
A study presented at SNM's 57th Annual Meeting shows that using multiple imaging agents with a hybrid imaging technique can be a valuable tool for accurately diagnosing and determining treatment for a variety of diabetes-associated foot diseases. A common complication from Type 2 diabetes is the decreased ability to heal from even the most minor infections. Due to reduced blood circulation and nerve damage associated with the disease, infections of the feet are a major concern.
View SourceJune 7, 2010Provides Information
Final results of VIAject vs. RHI Phase 3 study in type 2 diabetes patients presented at 70th ADA
The final results of a six-month, multi-center, open-label Phase 3 study of VIAject® (more-rapid-acting injectable human insulin) versus regular human insulin (RHI) in 471 patients with type 2 diabetes were presented today by Helena Rodbard, M.D., at the 70th Scientific Sessions of the American Diabetes Association. Dr. Rodbard was a principal investigator of this study, which was designed to evaluate the safety and efficacy of VIAject® versus regular human insulin when used in combination with insulin glargine.
View SourceJune 28, 2010Provides Information
Finger-pricks a thing of the past
ETH-Zurich researchers have developed a new kind of sensor that can immediately gauge whether a person is suffering from type 1 diabetes upon coming into contact with their breath.
View SourceMay 12, 2010Provides Information
Flame-Made Nanosensors Detecting Type 1 Diabetes
ETH-Zurich researchers have developed a new kind of sensor that can immediately gauge whether a person is suffering from type 1 diabetes upon coming into contact with their breath.
View SourceMay 11, 2010Provides Information
Frequent doctor visits help diabetics lower blood pressure more quickly
Frequent doctor visits helped diabetes patients lower their high blood pressure to normal quicker, according to a large study reported in Hypertension: Journal of the American Heart Association.
View SourceMay 24, 2010Provides Information
Frequent napping is associated with increased risk of type 2 diabetes in older adults
A study in the March 1 issue of the journal Sleep shows that frequent napping is associated with an elevated prevalence of type 2 diabetes and impaired fasting glucose in an older Chinese population.
View SourceMarch 1, 2010Provides Information
Future Directions For Medtronic
Medtronic is one of the largest, if not the largest, medical device company in the world. So the direction they see medical gadgets heading in is probably a pretty good indicator of where they, and all of us, are going to go. Last week Medtronic announced at an investor meeting that they had 60 major new products coming out next year and they continue to buy smaller companies at an impressive rate. Aside from buying companies, they also act as almost VCs for several startups where they have seats on the boards.
View SourceJune 24, 2010Provides Information
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Gastric bypass surgery improves insulin sensitivity in Type 2 diabetes patients
Gastric bypass surgery improves Type 2 diabetes by other mechanisms in addition to weight loss and does so better than a low-calorie diet despite achieving equal weight loss, a new study finds. The results will be presented Monday at The Endocrine Society's 92nd Annual Meeting in San Diego.
View SourceJune 21, 2010Provides Information
Gene provides a link between lower birth weight and type 2 diabetes
New research uncovers two genetic regions that influence birth weight. One of the regions is also associated with type 2 diabetes, which helps to explain why small babies have higher rates of diabetes in later life.
View SourceApril 7, 2010Provides Information
Gene therapy reverses type 1 diabetes in mice
Researchers have developed an experimental cure for Type 1 diabetes, a disease that affects about one in every 400 to 600 children and adolescents. They will present their results in a mouse model of Type 1 diabetes on Sunday at The Endocrine Society's 92nd Annual Meeting in San Diego.
View SourceJune 21, 2010Provides Information
Genes may exert opposite effects in diabetes and inflammatory bowel disease
Pediatric researchers analyzing DNA variations in type 1 diabetes and inflammatory bowel disease have found a complex interplay of genes. Some genes have opposing effects, raising the risk of one disease while protecting against the other. In other cases, a gene variant may act in the same direction, raising the risk for both diseases.
View SourceMarch 22, 2010Provides Information
Genetic basis of alopecia areata established for first time
A team of investigators led by Columbia University Medical Center has uncovered eight genes that underpin alopecia areata, one of the most common causes of hair loss, as reported in a paper in the July 1, 2010 issue of Nature. Since many of the genes are also implicated in other autoimmune diseases, including rheumatoid arthritis and type 1 diabetes - and treatments have already been developed that target these genes - this discovery may soon lead to new treatments for the 5.3 million Americans suffering from hair loss caused by alopecia areata.
View SourceJune 30, 2010Provides Information
Genetic variations linked with development of ESRD in Chinese patients with diabetes
Examination of a gene involved in cell signaling finds that four common variants of this gene are associated with the development of end-stage renal disease in Chinese patients with type 2 diabetes, according to a study in the August 25 issue of JAMA.
View SourceAugust 24, 2010Provides Information
Generex Biotechnology announces plan to obtain cost reimbursement coverage for Generex Oal-lyn
Generex Biotechnology Corporation, the leader in drug delivery for metabolic diseases through the inner lining of the mouth, today announced that it has established an action plan for obtaining cost reimbursement coverage for Generex Oal-lyn™, including the development of an insurance product that covers the costs of Generex Oral-lyn™ and any additional and/or comparable diabetes products.
View SourceApril 19, 2010Provides Information
Germany diabetes care devices market report from GlobalData
Research and Markets has announced the addition of GlobalData's new report "Germany Diabetes Care Devices Market Outlook to 2016" to their offering.
View SourceMay 21, 2010Provides Information
Glucose Monitor Could Go From on the Belt to In the Belly
Researchers led by Bioengineering Professor David Gough at UCSD have reported, in a paper in Science Translational Medicine, that they implanted a wireless telemetry CGM in two pigs (222 and 520 days, respectively) and the device was successfully reporting glucose levels to an external receiver. Following human testing and FDA approval, devices such as these could replace similar systems that are external to the body with a needle-attachment that pierces the skin to take measures. Combined with potential transdermal or intranasal insulin administration, this technology could lead to less sticking and poking of diabetics.
View SourceJuly 29, 2010Provides Information
Glucose monitoring device helps to manage pets’ diabetes
The treatment of diabetes was revolutionized in 1922 when insulin was isolated from dogs. Since then, significant advances in human medicine have made diabetes more manageable for patients. Now, human medicine has returned the favor and used these advances to help dogs with diabetes. A University of Missouri researcher is using a continuous glucose monitoring device - commonly used in humans with diabetes - to help treat dogs and other animals.
View SourceJuly 26, 2010Provides Information
Government has yet to confirm funding for ADI
With the sunset date for the Aboriginal Diabetes Initiative (ADI) rapidly approaching, the government has yet to confirm whether or not funding will continue after March 31st.
View SourceMarch 1, 2010Provides Information
Grapefruit's bitter taste holds a sweet promise for diabetes therapy
Naringenin, an antioxidant derived from the bitter flavor of grapefruits and other citrus fruits, may cause the liver to break down fat while increasing insulin sensitivity, a process that naturally occurs during long periods of fasting.
View SourceAugust 25, 2010Provides Information
Grapes Reduce Risk Factors for Heart Disease and Diabetes, Animal Study Shows
Could eating grapes slow what's for many Americans a downhill sequence of high blood pressure and insulin resistance leading to heart disease and type 2 diabetes?
View SourceMay 10, 2010Provides Information
Green Leafy Veggies May Cut Diabetes Risk
Study: Putting More Green Leafy Vegetables in Your Diet May Reduce Risk of Developing Type 2 Diabetes
View SourceAugust 19, 2010Provides Information
GUMC to co-host Caribbean Nights to benefit people living with diabetes
Kenneth Beatrice and David Nelson, MD, chair of the Department of Pediatrics at GUMC, will co-host "Caribbean Nights," an evening filled with drinks, dinner, dancing and a 'live' auction to benefit one of Washington's most important causes—diabetes—on April 24th at the Georgetown University Conference Center.
View SourceApril 23, 2010Provides Information
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HbA1c can be deceptive in African American children with diabetes: Study
Racial disparities could result in life-threatening hypoglycemia and increased complications
View SourceMay 5, 2010Provides Information
Hopkins team discovers sweet way to detect prediabetes
Having discovered a dramatic increase of an easy-to-detect enzyme in the red blood cells of people with diabetes and prediabetes, Johns Hopkins scientists say the discovery could lead to a simple, routine test for detecting the subtle onset of the disease, before symptoms or complications occur and in time to reverse its course.
View SourceJuly 8, 2010Provides Information
Hot tip: Target inflammation to ease obesity ills
What if you could be fat but avoid heart disease or diabetes? Scientists trying to break the fat-and-disease link increasingly say inflammation is the key.
View SourceMarch 1, 2010Provides Information
How muscle cells control fatty acid uptake
A new study from the Swedish medical university Karolinska Institutet shows that the blood vessels and muscles of the heart can regulate the uptake of fatty acids that we ingest through meat, milk products and other food. The researchers behind the study have also identified the way in which regulation is governed by the muscles themselves. The results, which are published in the scientific journal Nature, open the way for new forms of treatment for pathological fat accumulation in the muscles which, in turn, increases the risk of type II (adult) diabetes and cardiovascular disease.
View SourceMarch 15, 2010Provides Information
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IMAGE project to be launched for prevention of type 2 diabetes
Researchers and clinicians from across the UK have been part of a pan-European team that has developed the first Europe wide strategy for the prevention of type 2 diabetes. The project received substantial funding of -1.2 million from the European Union (EU).
View SourceApril 9, 2010Provides Information
Implanted glucose sensor works for more than one year, could aid diabetes patients
Bioengineers developed an implantable glucose sensor and wireless telemetry system that continuously monitors tissue glucose and transmits the information to an external receiver. The paper, to be published in the July 28, 2010 issue of the journal Science Translational Medicine, describes the use of this glucose-sensing device as an implant in animals for over one year. After human clinical trials and FDA approval, the device may be useful to people with diabetes as an alternative to finger sticking and short-term, needle-like glucose sensors that have to be replaced every 3 to 7 days.
View SourceJuly 28, 2010Provides Information
Importance of insulin delivery devices for diabetes management
The growing use of insulin delivery devices such as pens and pumps may help individuals with diabetes optimize blood glucose control and minimize their risk for chronic health problems associated with diabetes, as described in a Special Supplement to Diabetes Technology & Therapeutics, a peer-reviewed journal published by Mary Ann Liebert, Inc..
View SourceJune 8, 2010Provides Information
In the ring: Researchers fighting bacterial infections zero in on microorganism's soft spots
In any battle, sizing up one's opponent is a critical first step. For researchers fighting a bacterial infection, that means assessing every nook and cranny of the malicious microorganism and identifying which ones to attack.
View SourceJuly 13, 2010Provides Information
Increased cancer risk of people with type 2 diabetes
Cancer and diabetes - are risk factors the same for these two diseases? Or does diabetes cause processes in the body which promote the onset or growth of cancer? It is still unclear why diabetics have a higher rate of cancer than people who are not affected by this metabolic disorder.
View SourceMay 21, 2010Provides Information
Independent management of diabetes a huge issue for teens
It is hard enough being a teenager - or the parent of a teenager - without also having to deal with type 1 diabetes. Keeping good control can be a problem when the responsibility for administering insulin and checking blood glucose levels passes from parent to child.
View SourceApril 9, 2010Provides Information
Inflammation in body fat is not only pernicious
It has been a common opinion that inflammation in adipose tissue may cause insulin resistance, and thereby type 2 diabetes. However, recent research from the Swedish medical university Karolinska Institutet, published in the New England Journal of Medicine, question the theory that inflammation in the body fat is only pernicious. Instead the findings suggest that a certain form of body fat inflammation is necessary for fat cell turnover in the lean, healthy state.
View SourceMarch 25, 2010Provides Information
Inhaled Insulin May Help Treat Diabetes
Study Shows Inhaled Insulin May Be an Alternative to Injections for Type 2 Diabetes Patients
View SourceJune 24, 2010Provides Information
Injectable Glowing Beads In Bloodstream Can Indicate Glucose Levels
Japanese "Life Beans" project aims to ease monitoring for diabetics
View SourceAugust 6, 2010Provides Information
Innocoll submits SPA for phase 3 clinical trial of Cogenzia for adjuvant treatment of infected diabetic foot ulcers
Innocoll, Inc. announced that its wholly-owned subsidiary, Innocoll Technologies Ltd., has submitted a Special Protocol Assessment (SPA) for a proposed phase 3 clinical trial to support the U.S. approval of Cogenzia™: Innocoll's topical antibiotic therapy for the adjuvant treatment of infected diabetic foot ulcers.
View SourceJuly 13, 2010Provides Information
Insulin peptide may point to a solution for type 1 diabetes
Researchers at National Jewish Health and the University of Colorado Anschutz Medical Campus have identified the precise protein fragment, or peptide, that can trigger diabetes in mice. The finding, published in the June 15, 2010, issue of the Proceedings of the National Academy of Sciences, supports an emerging theory about the origins of autoimmunity, and may lead to new diagnostic and therapeutic strategies in humans.
View SourceJune 16, 2010Provides Information
Insulin reduces inflammation caused by obesity
Recent decades have seen a huge increase in type 2 diabetes and cardiovascular disease. This is a result of people being less active and eating fattier diets, which can lead to obesity and, in turn, diabetes. In a thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden, researchers have discovered properties of insulin which reduce inflammation caused by obesity and can therefore lower the risk of type 2 diabetes.
View SourceMay 10, 2010Provides Information
Intarcia presents ITCA 650 Phase 2 study results at 70th ADA
Intarcia Therapeutics, Inc. presented today the results of a phase 2 clinical study of ITCA 650 (DUROS® continuous subcutaneous delivery of exenatide) for the treatment of type 2 diabetes as a late-breaker at the Annual Conference of the American Diabetes Association in Orlando, FL (June 25-29, 2010). Results of the phase 2 study demonstrated substantial reductions in HbA1c and body weight during the 12 weeks of treatment with ITCA 650 at both the 20 mcg/day and 40 mcg/day doses.
View SourceJune 28, 2010Provides Information
Intervention Lowered Obesity Rate in Youth at High Diabetes Risk, HEALTHY Study Finds
Number of overweight and obese youth fell in program and comparison schools
View SourceJune 28, 2010Provides Information
iPhone App "NovoDose" Helps Physicians Determine Insulin Needs
Novo Nordisk recently released an iPhone app meant to help physicians determine the insulin needs of their diabetic patients. The app is meant for healthcare professionals (it starts by asking if you really are a healthcare professional), but anyone may download it. The app conveniently assumes you will be using Novo Nordisk's insulin analog product line which includes their long acting (Levemir), short acting (NovoLog) and their NovoLog Mix 70/30.
View SourceSeptember 1, 2010Provides Information
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JANUMET results in greater blood sugar reductions in patients with type 2 diabetes compared to pioglitazone
New data were presented at the American Diabetes Association (ADA) 70th Annual Scientific Sessions from a study comparing JANUMET (sitagliptin/metformin) to pioglitazone.
View SourceJune 28, 2010Provides Information
JDRF announces key step on road to artificial pancreas
JDRF announced today another important step on the road to the development of an artificial pancreas - an automated system to better manage the blood sugar of people with type 1 diabetes - with the establishment of a research program to speed the development of faster-acting insulin.
View SourceAugust 17, 2010Provides Information
JDRF, Pfizer, Hadassah Medical Organization, The Hebrew University of Jerusalem form diabetes research collaboration
The Juvenile Diabetes Research Foundation, a leader in setting the agenda for diabetes research worldwide, said today that it will begin a diabetes research collaboration with Pfizer, Hadassah Medical Organization, and The Hebrew University of Jerusalem on drugs to replicate and regenerate insulin-producing cells in people with type 1 diabetes.
View SourceMarch 22, 2010Provides Information
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Kidney Disease Hides in People With Undiagnosed Diabetes
Millions of Americans may have chronic kidney disease (CKD) and not know it, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).
View SourceMarch 28, 2010Provides Information
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Landmark ACCORD Trial Finds Intensive Blood Pressure and Combination Lipid Therapies do not Reduce Combined Cardiovascular Events in Adults with Diabetes
Lowering blood pressure to normal levels — below currently recommended levels — did not significantly reduce the combined risk of fatal or nonfatal cardiovascular disease events in adults with type 2 diabetes who were at especially high risk for cardiovascular disease events, according to new results from the landmark Action to Control Cardiovascular Risk in Diabetes (ACCORD) clinical trial.
View SourceMarch 15, 2010Provides Information
Large Gap in Diabetes, Obesity Screening Among U.S. Health Clinics
A new nationwide study finds that some local health clinics do not offer diabetes screening or obesity prevention programs to their clients, who tend to be poor.
View SourceJune 23, 2010Provides Information
Leptin Therapy in Animal Models Shows Promise for Type 1 Diabetes
Using leptin alone in place of standard insulin therapy shows promise in abating symptoms of type 1 diabetes, UT Southwestern Medical Center researchers report.
View SourceMarch 24, 2010Provides Information
Linagliptin mono- and combination therapy improves blood glucose control
New phase III data demonstrate clinically meaningful improvements in blood glucose control with linagliptin mono- and combination therapy Linagliptin phase III data were presented for the first time this week at the 70th Scientific Sessions of the American Diabetes Association (ADA), showing that this investigational compound, a dipeptidyl peptidase (DPP)-4 inhibitor, achieved significant, sustained and clinically meaningful reductions in blood glucose as measured by haemoglobin A1c (HbA1c), fasting plasma glucose (FPG), and postprandial glucose (PPG) concentrations. Linagliptin is being investigated by Boehringer Ingelheim as a once-daily oral treatment in type 2 diabetes.
View SourceJune 28, 2010Provides Information
Long-acting insulin analogues in type 1 diabetes: No proof of additional benefit
It has so far not been proven that the long-acting insulin analogues (LAIAs) insulin detemir (trade name: Levemir) and insulin glargine (trade name: Lantus), which are approved for the treatment of type 1 diabetes, offer patients an additional benefit versus long-acting human insulin. This applies to adults as well as to children and adolescents. This is the result of the final report published by the Institute for Quality and Efficiency in Health Care (IQWiG) on 19 April 2010.
View SourceMay 12, 2010Provides Information
Low Vitamin D Linked to Poor Diabetes Control
Study Finds Vitamin D Deficiency Common in People With Diabetes
View SourceJune 21, 2010Provides Information
Lower Levels of 'Rotten Egg' Gas (Hydrogen Sulfide) in Blood Linked to Obesity, Type 2 Diabetes and Poorer Circulation
Researchers from the Peninsula Medical School in Exeter have for the first time identified a link between blood levels of the gas hydrogen sulfide (a gas more commonly associated with the smell of rotten eggs), obesity and type 2 diabetes.
View SourceApril 28, 2010Provides Information
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Major depression more than doubles risk of dementia among adults with diabetes
Adults who have both diabetes and major depression are more than twice as likely to develop dementia, compared to adults with diabetes only, according to a study published in the recent Journal of General Internal Medicine.
View SourceMarch 5, 2010Provides Information
MannKind receives FDA Complete Response letter for AFREZZA NDA
MannKind Corporation today announced that it has received a Complete Response letter from the U.S. Food & Drug Administration (FDA) regarding the New Drug Application (NDA) for AFREZZA™ Inhalation Powder for the treatment of adult patients with type 1 and type 2 diabetes mellitus for the control of hyperglycemia.
View SourceMarch 15, 2010Provides Information
Many people with diabetes do not know or heed dangers of hot weather
A new survey shows that diabetic individuals who live in a hot climate have important gaps in their "heat awareness," or knowledge about proper diabetes self-care in hot weather, even though diabetes raises their risk of heat illness. The results of "Diabetes in the Desert: What Do Patients Know About the Heat?" will be presented Monday at The Endocrine Society's 92nd Annual Meeting in San Diego.
View SourceJune 21, 2010Provides Information
Mass. General Hospital announces completion of Phase I diabetes trial
Massachusetts General Hospital (MGH) and the Iacocca Foundation announce today the completion of the Phase I BCG clinical trial in type 1 diabetes, as well as the submission of all safety reports to the U.S. Food and Drug Administration (FDA) and the MGH data safety monitoring boards. Plans for the Phase II clinical study, which will continue the investigation of bacillus Calmette-Guerin (BCG) vaccination as a treatment for people with existing type 1 diabetes, are actively underway.
View SourceJune 28, 2010Provides Information
Maybe software can make American kids less fat, USDA opens voting on candidates
In March, First Lady Michelle Obama's "Lets Move" initiative for childhood health and fitness launched a contest called "Apps for Healthy Kids," offering $60,000 in prizes for software that encourages children to choose healthier foods and more active lifestyles. Today, the US Department of Agriculture has announced 95 finalists in the contest, which the public can test, and then vote on.
View SourceJuly 14, 2010Provides Information
Mechanism explains complications associated with diabetes
New research uncovers a molecular mechanism that links diabetes with an increased risk of cardiovascular problems and sudden cardiac death. The study, published by Cell Press in the June 24 issue of the journal Neuron, finds that high blood sugar prevents vital communication between the brain and the autonomic nervous system, which controls many involuntary activities in the body.
View SourceJune 23, 2010Provides Information
Medications to Treat Diabetic Nerve Pain
You can soothe the pain of diabetic neuropathy when controlling blood sugar isn't enough.
View SourceJune 2, 2010Provides Information
Medtronic Answers Reader Questions
You asked, Medtronic answered. As part of our story on the future of Medtronic, we gave the company a list of questions from our readers. Brian Henry, the Senior Director, Media Relations got back to us via email with the following.
View SourceJune 25, 2010Provides Information
Medtronic launches iPro2 Professional CGM system to help improve diabetes management
Medtronic, Inc. announced today the launch of iPro™2 Professional CGM, a continuous glucose monitoring (CGM) system used by physicians to help improve diabetes management, in 49 countries around the world. This simplified, yet more advanced fourth-generation CGM system is valuable for detecting high and low glucose fluctuations that can lead to dangerous health complications, which often go undetected with traditional A1C tests (a measurement of glucose control over a two-to-three-month period) and glucose meter measurements.
View SourceJune 7, 2010Provides Information
Medtronic's MiniMed Paradigm REAL-Time Revel System Receives FDA Approval
Medtronic has received FDA approval for its integrated diabetes management system called MiniMed Paradigm REAL-Time Revel System. The system combines insulin pump therapy, continuous glucose monitoring and diabetes therapy management software.
View SourceMarch 19, 2010Provides Information
Mendor Portable Blood Glucose Meter Announced
Mendor, a new company out of Helsinki, Finland, is preparing to launch a new blood glucose meter that is promised to be easier and more discreet to use than currently available models. The device, soon to be available in Europe, has a built in mechanical lancer and test strips
View SourceMarch 15, 2010Provides Information
Metabolic fingerprints offer fresh clues and a new path toward personalized medicine
Human metabolism proves to be as variable and individual as people's appearance or build -- despite nearly identical genetic inheritance. Better understanding of the differences could, for example, lead to more effective screening and treatment for diabetes and cardiovascular disease. Pioneering "metabolomics" as a path toward personalized medicine and nutrition, Munich area researchers have harnessed capabilities ranging from NMR and mass spectrometry to bioinformatics, all within a framework for conducting human studies.
View SourceApril 9, 2010Provides Information
Metformin may protect against lung cancer
Metformin, a drug commonly used to treat type 2 diabetes, shows potential in the prevention of tobacco-induced lung tumors, according to early research conducted at the National Cancer Institute (NCI).
View SourceSeptember 1, 2010Provides Information
Mind over matter? The psychology of healing
People suffering from diabetes-related foot ulcers show different rates of healing according to the way they cope and their psychological state of mind, according to new research by a health psychologist at The University of Nottingham.
View SourceAugust 2, 2010Provides Information
Mismanagement of diabetes leads to fatal accident
One of the worst case scenarios that can happen to a diabetic is if he or she falls into a hypoglycemic coma. This is caused by a severe deficiency in glucose levels found in the blood which causes the brain to seek other energy sources at the same time shutting down other important body functions. If treatment is delayed or neglected by the diabetic person, such a coma can cause not only loss of consciousness but also irreversible brain damage and death.
View SourceJuly 26, 2010Provides Information
MIT diabetes device monitors glucose with light
Imagine simply shining a light on your skin to determine how much sugar is in your blood. Researchers at MIT are developing a glucose-monitoring device for diabetes patients that may help do away with finger pricks.
View SourceAugust 10, 2010Provides Information
Molecular link between diabetes and schizophrenia connects food and mood
Defects in insulin function - which occur in diabetes and obesity - could directly contribute to psychiatric disorders like schizophrenia.
View SourceJune 8, 2010Provides Information
Morning test helps doctors save kidneys
A morning urine test is superior to all other tests for detecting declining kidney performance in patients with diabetic kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results suggest that clinicians should monitor kidney function by measuring the albumin:creatinine ratio from a first morning urine sample.
View SourceJuly 15, 2010Provides Information
Mothers' high blood sugar in pregnancy is linked to children's reduced insulin sensitivity
Children of mothers whose blood glucose (sugar) was high during pregnancy are more likely to have low insulin sensitivity—a risk factor for type 2 diabetes—even after taking into consideration the children's body weight, a new study shows.
View SourceJune 22, 2010Provides Information
Muscle gene may provide new treatments for obesity and diabetes
Skeletal muscle enables us to walk, run or play a musical instrument, but it also plays a crucial role in controlling disease. Rockefeller University scientists have now shown how a specific molecule in skeletal muscle regulates energy expenditure, a finding that may lead to new treatments for certain muscle diseases as well as diabetes, obesity and heart disease.
View SourceJuly 27, 2010Provides Information
Muscular Problems in Children With Neonatal Diabetes Are Neurological, Study Finds
The muscle weakness and coordination problems sometimes seen in patients with neonatal diabetes -- a rare, inherited form of diabetes -- are caused by problems in the brain rather than the muscles, according to new research. The findings could pave the way for the development of improved treatments for the disease.
View SourceJuly 1, 2010Provides Information
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'Nano-tattoo' may help diabetics track their blood sugar
People with type I diabetes must prick their fingers several times a day to test their blood sugar level. Though the pain is minor, the chore interferes with daily life.
View SourceMay 28, 2010Provides Information
Nanotech breath sensor detects diabetes and potentially serious complication
Scientists are reporting development and successful testing of a sensor that can instantly tell whether someone has Type I diabetes. It could also be used by emergency room doctors to determine whether a patient has developed diabetic ketoacidosis, a potentially serious complication that happens when diabetics do not take enough insulin. Someday the technology may also be used by diabetics, in their own homes, to determine whether they need more insulin.
View SourceMay 20, 2010Provides Information
Nanotechnology sensor detects type 1 diabetes in breath
Acetone is also found in a healthy person’s breath, but the concentration is only about 900 ppb (particles per billion); in people suffering from type 1 diabetes, however, the concentration is double that; and in the case of a ketoacidosis it can be even higher. That’s why the sensor developed at ETH Zurich works so well: it can detect as few as 20 ppb of acetone and even works at extremely high humidity levels of over 90 percent – like in the human breath.
View SourceMay 11, 2010Provides Information
'Nanovaccine' reverses type 1 diabetes in mice
A new study, published online April 8 by Cell Press in the journal Immunity, describes a unique therapeutic "nanovaccine" that successfully reverses diabetes in a mouse model of the disease. In addition to providing new insight into diabetes, the research also reveals an aspect of the pathogenesis of the autoimmune response that may provide a therapeutic strategy for multiple autoimmune disorders.
View SourceApril 8, 2010Provides Information
Near-normal blood sugar target did not delay risk of organ damage in people with diabetes
In people with longstanding type 2 diabetes who are at high risk for heart attack and stroke, lowering blood sugar to near-normal levels did not delay the combined risk of diabetic damage to kidneys, eyes, or nerves, but did delay several other signs of diabetic damage, a study has found. The intensive glucose treatment was compared with standard glucose control.
View SourceJune 29, 2010Provides Information
NEJM: Sensor-Augmented Pump Therapy Shows Promise in Diabetes Study
Coinciding with a presentation at the American Diabetes Association, the New England Journal of Medicine published an industry supported study on the effectiveness of Sensor-Augmented Insulin-pumps, concluding that such a technology "resulted in significant improvement in glycated hemoglobin levels, as compared with injection therapy." This study used the MiniMed Paradigm REAL-Time System from Medtronic. In our recent story on Medtronic, we talked about their interest in closed-loop diabetes management.
View SourceJune 30, 2010Provides Information
New associations between diabetes, environmental factors found by novel analytic technique
Got diabetes? If so, you probably know that the adult-onset form of the disease can be triggered by, among other things, obesity and a fatty diet. You're also more likely to develop diabetes if other family members have it. But a new study by researchers at the Stanford University School of Medicine suggests that you should also begin looking suspiciously at other aspects of your life — like your past exposure to certain pesticides or chemicals and even one form of vitamin E.
View SourceMay 20, 2010Provides Information
New alterations found in young adults with type 2 diabetes
Diet and aerobic exercise are highly effective for the treatment of type 2 diabetes, but not for obese subjects that have developed the disease when very young.
View SourceMarch 11, 2010Provides Information
New biotech company grows from MCG diabetes and genomic research
A new biotech company has grown out of laboratory and clinical studies at the Medical College of Georgia with the goal of improving the diagnosis and treatment of diabetes and cancer.
View SourceJuly 19, 2010Provides Information
New Brunswick's economic cost of diabetes to increase to $427M by 2020, if left unchecked
Canadian Diabetes Association urges governments to take immediate action to introduce comprehensive diabetes strategies.
View SourceMay 31, 2010Provides Information
New culprit in muscle defects, insulin resistance that come with age
Type 2 diabetes is a widespread problem for many people these days, and our risk for insulin resistance and diabetes only grows as we age. Now, a new report in the May issue of Cell Metabolism reveals a new contributor to the problem: The muscles of elderly people and of people with type 2 diabetes contain lower concentrations of a protein known as PARL (short for "presenilin-associated rhomboid-like").
View SourceMay 4, 2010Provides Information
New diabetes risk assessment developed
A team from the University of Leicester, led by Professor Melanie Davies from the Department of Cardiovascular Sciences and Professor Kamlesh Khunti from the Department of Health Sciences, has developed an easy way for people to assess their risk of having diabetes.
View SourceAugust 11, 2010Provides Information
New device for patients to monitor blood glucose levels
People with type 1 diabetes must keep a careful eye on their blood glucose levels: Too much sugar can damage organs, while too little deprives the body of necessary fuel. Most patients must prick their fingers several times a day to draw blood for testing.
View SourceAugust 9, 2010Provides Information
New evidence that drinking coffee may reduce the risk of diabetes
Scientists are reporting new evidence that drinking coffee may help prevent diabetes and that caffeine may be the ingredient largely responsible for this effect. Their findings, among the first animal studies to demonstrate this apparent link, appear in ACS' Journal of Agricultural and Food Chemistry.
View SourceJune 9, 2010Provides Information
New immigrants have higher risk of diabetes than long-term residents
New immigrants, especially women and those of South Asian or African descent, have a higher risk of diabetes compared with long-term residents of Ontario, found a research study in CMAJ (Canadian Medical Association Journal).
View SourceApril 19, 2010Provides Information
New OneTouch Delica Lancing System for More Comfortable and Gentle Glucose Testing
J&J's LifeScan has released a new lancing device that the firm says is less painful and easier to use than similar products currently on the market. The OneTouch Delica System features a thinner lancet that is applied swiftly in a straight line that supposedly helps prevent vibrations that can cause unnecessary pain.
View SourceJune 30, 2010Provides Information
New pathway to cheap insulin
More than eight million diabetics live in Germany. Diabetes is not restricted to our prosperous society and the highest growth rates often occur in countries with aspiring economies such as in Asia. Worldwide, more than 285 million people suffer from this illness; with 50 million diabetics, India is the country with the most people affected by this disease. In Europe, Germany shows the highest prevalence in the population with twelve percent. In a German-Indo collaboration, researchers from the Helmholtz-Centre for Infection Research (HZI) in Braunschweig, Germany have now developed a new method to cheaply produce insulin for the treatment of diabetes. The group's results have now been published in the open access online research magazine Microbial Cell Factories. With this, all information is freely accessible for everyone and is not subject to patent law.
View SourceMay 26, 2010Provides Information
New report provides key market data on Italy diabetes care devices market
Research and Markets has announced the addition of GlobalData's new report "Italy Diabetes Care Devices Market Outlook to 2016" to their offering.
View SourceMay 24, 2010Provides Information
New research shows cellular changes in fat tissue lead to type 2 diabetes
Cellular changes in fat tissue-not the immune system-lead to the "hyperinflammation" characteristic of obesity-related glucose intolerance and type 2 diabetes, according to new research from the University of Cincinnati (UC).
View SourceJuly 7, 2010Provides Information
New Role for Master Regulator in Cell Metabolism, Response to Stress: Clinical Implications for Obesity, Diabetes and Cancer Research
AMP-activated protein kinase, or AMPK, is a master regulator protein of metabolism that is conserved from yeast to humans. When a cell is low on fuel, AMPK shuts down processes that use energy and turns on processes that produce energy.
View SourceJuly 15, 2010Provides Information
New study finds attending Weight Watchers meetings helps reduce the risk for type 2 diabetes
The 57 million Americans currently living with "pre-diabetes" could benefit from a group weight loss program, like Weight Watchers, according to a new study published in this month's American Journal of Lifestyle Medicine. Researchers found that after a 6-month Weight Watchers group program, overweight or obese adults who attended at least two thirds of the weekly sessions, not only lost weight, but also significantly reduced fasting glucose and insulin levels - important indicators of diabetes risk.
View SourceMay 20, 2010Provides Information
New Study May Explain How Weight-loss Surgery Reverses Type 2 Diabetes
A team of researchers, led by a UC Davis veterinary endocrinologist, has shown for the first time that a surgical procedure in rats that is similar to bariatric surgery in humans can delay the onset of type 2 diabetes. The researchers also have identified biochemical changes caused by the surgeries that may be responsible for that delay.
View SourceMarch 24, 2010Provides Information
New technique to probe hidden dynamics of molecular biology
Funded by a $1 million grant from the W.M. Keck Foundation, University of Chicago scientists are aiming to develop a reliable method for determining how biological processes emerge from molecular interactions. The method may permit them to "rewire" the regulatory circuitry of insulin-secreting pancreatic beta cells, which play a major role in type-2 diabetes.
View SourceMarch 3, 2010Provides Information
New treatment for crippling diabetic Charcot foot
The alarming increase of morbidly obese diabetics is causing more new cases of a debilitating foot deformity called Charcot foot.
View SourceJuly 14, 2010Provides Information
Nicer than needles: Insulin pills for diabetes finally in clinical trials
After years of research and anticipation, insulin pills that could make it easier for millions of patients worldwide to manage diabetes are finally moving ahead in clinical trials and a step-closer to the medicine cabinet. That's among the topics highlighted in a two-part cover story on drug manufacturing in the current issue of Chemical & Engineering News.
View SourceJune 2, 2010Provides Information
NIH Study Finds That Overweight Girls Who Lose Weight Reduce Adult Diabetes Risk
Overweight girls who lose weight before they reach adulthood greatly reduced their risk for developing type 2 diabetes, according to researchers from the National Institutes of Health and Harvard University, who analyzed 16 years of data on nearly 110,000 women.
View SourceMay 27, 2010Provides Information
No Link Between Diabetes Drug Rosiglitazone and Increased Rate of Heart Attack, Study Finds
The diabetes drug rosiglitazone has been under intense scrutiny since a 2007 study in the New England Journal of Medicine looked at more than 40 clinical trials and linked the drug's use with increased risk of heart attack and death from heart disease.
View SourceJune 29, 2010Provides Information
NOXXON to commence multiple ascending dose study of MCP-1 targeting anti-inflammatory Spiegelmer NOX-E36
NOXXON Pharma AG announced today that it has permission to commence a multiple ascending dose study of its Monocyte Chemoattractant Protein-1 (MCP-1) targeting anti-inflammatory Spiegelmer®, NOX-E36. NOXXON plans to develop NOX-E36 for the treatment of diabetic nephropathy and other diabetes related complications.
View SourceJuly 7, 2010Provides Information
Novel Anti-Diabetes Mechanism Uncovered: Findings Could Lead to Next Generation of Improved Therapies
In a joint study, scientists from The Scripps Research Institute and the Dana-Farber Cancer Institute at Harvard University have uncovered a novel mechanism that dramatically increases insulin sensitivity and reduces the risk of developing type 2 diabetes and cardiovascular disease.
View SourceJuly 22, 2010Provides Information
Novel MC4R agonist exhibits potential as new treatment for obesity, diabetes
Rhythm, a biotechnology company developing peptide therapeutics for metabolic diseases, today announced a study of obese primates treated with RM-493 showing a reversal of obesity and insulin resistance, and improvement in both heart rate and blood pressure. RM-493 is a novel peptide agonist targeting the melanocortin 4 receptor (MC4R) that is a clinical candidate for the treatment of obesity and diabetes.
View SourceJune 22, 2010Provides Information
Novel nanoparticle vaccine cures type 1 diabetes in mice
Using a sophisticated nanotechnology-based “vaccine,” researchers were able to successfully cure mice with type 1 diabetes and slow the onset of the disease in mice at risk for the disease. The study, co-funded by the Juvenile Diabetes Research Foundation (JDRF), provides new and important insights into understanding how to stop the immune attack that causes type 1 diabetes, and could even have implications for other autoimmune diseases.
View SourceApril 8, 2010Provides Information
Novo Nordisk BlueSheet launched to provide information on diabetes and chronic disease
Novo Nordisk, a global healthcare company and leader in diabetes care, today announced the launch of the Novo Nordisk BlueSheet, a resource for information on diabetes and chronic disease, highlighting key issues in diabetes prevention, detection, treatment and care.
View SourceMarch 30, 2010Provides Information
Novo Nordisk recruits 60,000th patient in world's largest observational study in insulin therapy
Today, Novo Nordisk announced the landmark recruitment of the 60,000th patient in the A1chieve(R) study - an observational study designed to investigate the effects of modern insulins in the management of type 2 diabetes.
View SourceJuly 19, 2010Provides Information
Nutritional labeling and point-of-purchase signs influence healthy food choices
Poor diet and physical inactivity leading to obesity are poised to overtake tobacco use as the leading cause of preventable death in the United States. With over 30% of U.S. adults obese, the significant adverse health effects of obesity (including heart disease and diabetes) are widespread throughout the country. Two studies published in the August issue of the Journal of the American Dietetic Association shed light on behaviors regarding food choices and good nutrition and report on how nutritional labeling and point-of-purchase signs are influencing healthy food choices.
View SourceAugust 2, 2010Provides Information
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Obesity, diabetes epidemics continue to grow in California, study finds
A majority of adults in California are obese or overweight, and more than 2 million have been diagnosed with diabetes, according to a new study from the UCLA Center for Health Policy Research.
View SourceAugust 31, 2010Provides Information
Obesity Rating for Every American Must Be Included in Stimulus-Mandated Electronic Health Records, Says HHS
New federal regulations issued this week stipulate that the electronic health records--that all Americans are supposed to have by 2014 under the terms of the stimulus law that President Barack Obama signed last year--must record not only the traditional measures of height and weight, but also the Body Mass Index: a measure of obesity.
View SourceJuly 16, 2010Provides Information
Obesity, weight gain in middle age associated with increased risk of diabetes among older adults
For individuals 65 years of age and older, obesity, excess body fat around the waist and gaining weight after the age of 50 are associated with an increased risk of diabetes.
View SourceJune 22, 2010Provides Information
Omega imbalance can make obesity 'inheritable': study
Overeating combined with the wrong mix of fats in one's diet can cause obesity to be carried over from one generation to the next, researchers in France reported Friday.
View SourceJuly 16, 2010Provides Information
ONGLYZA-metformin combination: FDA accepts NDA for review
Bristol-Myers Squibb Company and AstraZeneca today announced that the U.S. Food and Drug Administration has accepted for review a New Drug Application for an investigational fixed dose combination of ONGLYZA™ (saxagliptin), a dipeptidyl peptidase-4 (DPP4) inhibitor, and metformin HCl extended-release tablets as a once-daily treatment for type 2 diabetes mellitus in adults. Bristol-Myers Squibb and AstraZeneca submitted the NDA with the U.S. FDA for saxagliptin/metformin HCl extended-release tablets on December 29, 2009.
View SourceMarch 17, 2010Provides Information
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Parents keep diabetic teens on track
Teenagers and "tweenagers" with type 1 diabetes have more trouble sticking to their treatment plan - thus raising their risk of blindness, kidney failure and heart disease - if their parents become increasingly lax about monitoring the child's treatment, or if the mother-child relationship is poor.
View SourceApril 7, 2010Provides Information
Patients with diabetes and depression control glucose, blood pressure just as well as non-depressed counterparts
A team of researchers at UW and Group Health Research Institute have found that patients with diabetes who are also depressed had similar levels of glycemia, blood pressure and lipid control compared with counterparts without depression.
View SourceJune 7, 2010Provides Information
Patients with diabetes may need fewer medications after bariatric surgery
Bariatric surgery appears to be associated with reduced use of medications and lower health care costs among patients with type 2 diabetes, according to a report in the August issue of Archives of Surgery, one of the JAMA/Archives journals.
View SourceAugust 16, 2010Provides Information
Patients with hyperglycaemia during acute illness have increased risk of developing diabetes: Researchers
Hyperglycemia during critical illness may be used as a warning of future diabetes. Researchers writing in BioMed Central's open access journal Critical Care have found a significant association between acute illness complicated with hyperglycaemia and the future development of type II diabetes or glucose intolerance.
View SourceJuly 8, 2010Provides Information
People with diabetes are at higher risk of atrial fibrillation
As the U.S. population keeps aging and gaining weight, diabetes is becoming increasingly common. Some research has associated diabetes with the most common kind of chronically irregular heartbeat, called atrial fibrillation, which can raise the risk for stroke and death. But results of past studies of diabetes and atrial fibrillation have conflicted. Now in the Journal of General Internal Medicine Dr. Sascha Dublin of Group Health Research Institute has linked diabetes to a 40 percent greater risk of developing atrial fibrillation; and she found this risk rises even higher the longer people have diabetes and the less controlled their blood sugar is.
View SourceApril 22, 2010Provides Information
Pilot study supports adolescent diabetes patients through personalized text messages
Jennifer Dyer, MD, MPH, an endocrinologist at Nationwide Children's Hospital, has developed and completed a pilot study that uses weekly, customized text messages to remind adolescent diabetes patients about their personal treatment activities. At the conclusion of the study, Dr. Dyer found an increase in overall treatment adherence and improved blood glucose levels.
View SourceJuly 30, 2010Provides Information
Popular diabetes drug works differently than thought
The popular diabetes medication metformin works in different fashion than the current widely accepted view. This new finding could lead to wider use of the drug—particularly in people with cancer and diseases linked to TSC deficiency like tuberous sclerosis and lymphangioleiomyomatosis (LAM).
View SourceMay 4, 2010Provides Information
Popular diabetes drugs associated with fractures in type 2 diabetic patients
Postmenopausal women with diabetes taking thiazolidinediones (TZDS), including rosiglitazone and pioglitazone, may be at increased risk for fractures according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Men with diabetes taking both loop diuretics and TZDs may also be at increased risk of fractures.
View SourceJuly 29, 2010Provides Information
Positive top-line results from Phenomix' Phase 3 trial of dutogliptin for Type 2 diabetes mellitus
Phenomix Corporation today announced positive top-line results from a six-month Phase 3 study comparing dutogliptin 400mg and 200mg once daily as monotherapy versus placebo for the treatment of patients with Type 2 diabetes mellitus. Dutogliptin is Phenomix' internally-discovered dipeptidyl peptidase-4 (DPP-4) inhibitor.
View SourceApril 20, 2010Provides Information
Postmenopausal women with diabetes taking TZDs at increased fracture risk
Postmenopausal women with diabetes taking thiazolidinediones (TZDS), including rosiglitazone and pioglitazone, may be at increased risk for fractures according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). Men with diabetes taking both loop diuretics and TZDs may also be at increased risk of fractures.
View SourceJuly 29, 2010Provides Information
Potential New Drug for Type 2 Diabetes
An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research.
View SourceMarch 17, 2010Provides Information
Prediabetes Precautions Often Ignored
Study Shows People With Prediabetes Don't Take Steps to Reduce Risk of Type 2 Diabetes
View SourceMarch 2, 2010Provides Information
Prevalence of eye disorder high among older US adults with diabetes
Nearly 30 percent of U.S. adults with diabetes over the age of 40 are estimated to have diabetic retinopathy, with about 4 percent of this population having vision-threatening retinopathy, according to a study in the August 11 issue of JAMA.
View SourceAugust 10, 2010Provides Information
Preventing blindness focus of ORNL technology, AMDx
Automated Medical Diagnostics, a startup company based in Memphis, envisions its product helping to preserve the sight of millions of people at risk of vision loss from diabetic retinopathy.
View SourceMay 5, 2010Provides Information
Pregnancy Weight Gain May Increase a Woman's Risk of Gestational Diabetes
The three-year study of 1,145 pregnant women from an ethnically diverse population found that women who gained more weight than is recommended by the Institute of Medicine had a 50 percent increased risk of developing gestational diabetes mellitus, also known as GDM. The association between pregnancy weight gain and gestational diabetes risk was more pronounced among overweight and non-white women. The study included 345 pregnant women with gestational diabetes and 800 pregnant women without gestational diabetes.
View SourceMarch 3, 2010Provides Information
Preventing diabetes key step to preventing kidney disease
If there were a one-word message to tell the story of World Kidney Day on March 11, Stanford physicians, researchers, dietitians, nurses would vote for "prevention."
View SourceMarch 8, 2010Provides Information
Protein important in diabetes may also play a key role in heart disease, other disorders
Studying a protein already known to play an important role in type 2 diabetes and cancer, genomics researchers have discovered that it may have an even broader role in disease, particularly in other metabolic disorders and heart disease. In finding unsuspected links to other disease-related genes, the scientists may have identified future targets for drug treatments.
View SourceJuly 21, 2010Provides Information
Proteus Pill Ingestion Monitoring System Gets EU Green Light
Proteus Biomedical has received CE Mark approval from the European Union to bring to market the firm's Raisin ingestible drug sensors and monitoring system. When a patient swallows tablets that have individually tagged beacons on them, a sensor can automatically record the precise time and basic vital signs of the patient at that time.
View SourceAugust 13, 2010Provides Information
pSivida announces FDA Priority Review status for Iluvien NDA
pSivida Corp., a leader in the development of sustained release back of the eye drug delivery systems for difficult-to-treat conditions, today announced that its licensee, Alimera Sciences has been notified that the U.S. Food and Drug Administration (FDA) has granted Priority Review status for the New Drug Application (NDA) filed for Iluvien for the treatment diabetic macular edema (DME).
View SourceAugust 31, 2010Provides Information
Public health advocate wants Avandia study halted
A leading public health advocate pressed his case Wednesday to halt a trial of GlaxoSmithKline's diabetes drug Avandia, telling a House subcommittee the pill needlessly increases patients' heart attack risk.
View SourceApril 28, 2010Provides Information
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Reduce Your Risk of Nerve Pain and Damage From Diabetes
If you have diabetes, chances are good that you already have some form of nerve pain or nerve damage, called diabetic neuropathy. "People with diabetes have about a 60% chance of getting neuropathy of any kind," says Dace L. Trence, MD, an endocrinologist and director of the Diabetes Care Center at the University of Washington Medical Center in Seattle. "It's probably an equal risk of getting neuropathy with type 1 and type 2 diabetes."
View SourceJune 2, 2010Provides Information
Reducing the health risks of obesity without serious side effects
The drug rimonabant was developed as a treatment for obesity and its myriad of serious health consequences (for example, type 2 diabetes). Despite having its desired effects on weight, which it decreased, and on levels of glucose and fats in the blood, rimonabant was never approved for use in the US because of serious neurological side effects including depression and anxiety.
View SourceJuly 26, 2010Provides Information
Remarkable Effects of Fat Loss on the Immune System
Australian scientists have shown for the first time that even modest weight loss reverses many of the damaging changes often seen in the immune cells of obese people, particularly those with Type 2 diabetes.
View SourceApril 20, 2010Provides Information
Report: 235 new medicines in development to treat diabetes
A record 235 new medicines to treat diabetes, one of the fastest-growing diseases in America, are being developed by America's pharmaceutical research and biotechnology companies, according to a national report unveiled today in Charleston.
View SourceMay 26, 2010Provides Information
Research points to two promising proteins for preventing diabetes
Two human proteins that evolutionary processes have conserved from ancient single-celled organisms appear to provide new targets of opportunity for scientists hoping to thwart the development of diabetes.
View SourceMay 24, 2010Provides Information
Researcher ready to test new diabetes treatment in humans
A longtime diabetes researcher at University of Texas Southwestern Medical School is setting up human tests for a new treatment he says might have fewer side effects than standard insulin therapy.
View SourceMarch 2, 2010Provides Information
Research shows some people don't taste salt like others
Low-salt foods may be harder for some people to like than others, according to a newly published study by a researcher in Penn State's College of Agricultural Sciences. The research indicates that genetics influence some of the difference in the levels of salt we like to eat.
View SourceMay 27, 2010Provides Information
Researchers develop agents that keep insulin working longer
More than half a century after researchers identified a promising way to treat diabetes based on blocking the breakdown of insulin in the body, a research team led by a scientist at the Mayo Clinic campus in Florida have developed potent molecules that can do just that.
View SourceMay 7, 2010Provides Information
Researchers Fighting Bacterial Infections Zero in on Microorganism's Soft Spots
In any battle, sizing up one's opponent is a critical first step. For researchers fighting a bacterial infection, that means assessing every nook and cranny of the malicious microorganism and identifying which ones to attack.
View SourceJuly 13, 2010Provides Information
Researchers identify 12 new genes linked to diabetes
An international consortium of scientists has identified 12 new genes associated with type 2 diabetes, in the largest study of the genetics of the condition to date.
View SourceJune 28, 2010Provides Information
Researchers identify method to help reduce fat in the blood
Over 60 per cent of Canadians are classified as overweight or obese. This epidemic is a concern for experts around the world. One of the major problems is high levels of lipids in the blood, which can lead to cardiovascular disease, fatty liver disease and Type 2 diabetes. But a University of Alberta researcher has taken a major step in protecting people against these diseases.
View SourceMarch 2, 2010Provides Information
Researchers identify protein that modulates metabolic dysfunction in obesity
Researchers from Boston University School of Medicine (BUSM) have discovered that Sfrp5, which refers to secreted frizzled-related protein 5, is an anti-inflammatory adipokine whose expression is disrupted in animal models of obesity and type 2 diabetes. The findings, which currently appear on-line in Science, may provide a new way of targeting metabolic disease, specifically obesity.
View SourceJune 17, 2010Provides Information
Researchers show some cells in pancreas can spontaneously change into insulin-producing cells
Alpha cells in the pancreas, which do not produce insulin, can convert into insulin-producing beta cells, advancing the prospect of regenerating beta cells as a cure for type 1 diabetes. The findings come from a study at the University of Geneva, co-funded by the Juvenile Diabetes Research Foundation, that is published today in the online edition of the scientific journal Nature.
View SourceApril 5, 2010Provides Information
Researchers test topical drug to treat diabetic macular edema
Early-stage human clinical trials showed that a new topical drug was safe and had biological effects in a type of diabetic eye disease, and may offer researchers a new approach to prevent and treat diabetic macular edema.
View SourceMarch 24, 2010Provides Information
Researchers to Develop New Microscopy Method to Image Inside Beta Cells
Funded by a $1 million grant from the W.M. Keck Foundation, University of Chicago scientists are aiming to develop a reliable method for determining how biological processes emerge from molecular interactions.
View SourceMarch 4, 2010Provides Information
Resveratrol Linked to Positive Impact on Pre-diabetes
Researchers at Albert Einstein College of Medicine of Yeshiva University have linked resveratrol, a chemical compound found in red wine, to improved health of patients with impaired glucose tolerance (IGT), also known as “pre-diabetes.”
View SourceJuly 1, 2010Provides Information
Rye and barley products facilitate blood glucose and appetite regulation
Evidence from observational studies indicates that diets rich in whole grain reduce risk of obesity and other diseases related to the metabolic syndrome e.g. type 2 diabetes and cardio-vascular disease. The mechanisms involved are only partially elucidated. Work within HEALTHGRAIN has revealed novel insights regarding some potential mechanisms.
View SourceMay 5, 2010Provides Information
RYGB surgery increases insulin activity in diabetes mellitus patients
Diabetes mellitus is a chronic metabolic disease resulted from, either decreased production of insulin or increased resistance to it from peripheral tissues or both factors combined together. While medical treatment remains the mainstay of treatment for diabetes, some surgical procedures, such as Roux-en-Y gastric bypass, have demonstrated some potential to be a treatment option for diabetes.
View SourceMay 13, 2010Provides Information
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Salsalate May Help Treat Type 2 Diabetes
Study Shows Painkiller May Reduce Blood Sugar Levels
View SourceMarch 15, 2010Provides Information
Science leaders urge diabetes patients to talk with doctor before making changes to medication use
The Endocrine Society, American Diabetes Association and American Association of Clinical Endocrinologists issue joint statement in response to an FDA panel's recommendation to keep rosiglitazone (Avandia) on the market
View SourceJuly 15, 2010Provides Information
Scientist discover important new player in diabetes onset
If you think of diabetes onset like an elaborate molecular drama, then a research team led by a La Jolla Institute scientist has unmasked a previously unknown cellular player, which is critical to proper insulin secretion. "Defective insulin secretion is a hallmark of both type 1 and type 2 diabetes," said Catherine Hedrick, Ph.D., a scientist at the La Jolla Institute for Allergy & Immunology, who led the team, which included researchers from the University of Virginia.
View SourceJune 7, 2010Provides Information
Scientists find unsuspected molecular link between obesity and insulin resistance
A new understanding of insulin resistance and the action of diabetes drugs such as Avandia and Actos could pave the way for improved medications that are more selective and safer, say scientists from Dana-Farber Cancer Institute and The Scripps Research Institute.
View SourceJuly 21, 2010Provides Information
Scientists reveal how genetic mutations may cause type 1 diabetes
Scientists from The Scripps Research Institute have provided an answer to the 40-year-old mystery of how certain genetic mutations lead to Type 1 diabetes. This new molecular understanding could lead to novel therapies for Type 1 diabetes and other autoimmune diseases.
View SourceApril 19, 2010Provides Information
Sea creatures' sex protein provides new insight into diabetes
A genetic accident in the sea more than 500 million years ago has provided new insight into diabetes, according to research from Queen Mary, University of London.
View SourceMarch 22, 2010Provides Information
Second issue of Novo Nordisk BlueSheet highlights information on diabetes
Novo Nordisk Inc., a global healthcare company and leader in diabetes care, today announced the second issue of the Novo Nordisk BlueSheet, a resource for information on diabetes and chronic disease, highlighting key issues in diabetes prevention, detection, treatment and care.
View SourceJuly 13, 2010Provides Information
Sensor and insulin pump results in better blood-sugar control in all age groups with diabetes
Adding a continuous blood sugar level sensor to an insulin pump helps patients with type 1 diabetes achieve better blood sugar control compared to the common standard of care, multiple daily insulin injections, concludes a study published on-line today in the New England Journal of Medicine.
View SourceJune 29, 2010Provides Information
Simple diagnostic tool predicts Type 2 diabetes in Southeast Asians
Australian and Vietnamese researchers have estimated the current prevalence of Type 2 diabetes in Vietnam, and have developed a simple tool for identifying individuals at high risk.
View SourceJuly 8, 2010Provides Information
Small molecule induces insulin expression in pancreatic alpha-cells
Researchers at the Broad Institute of Harvard and MIT have made an important first step in identifying a potential new avenue for developing novel diabetes therapies. Diabetes results when the body destroys its own insulin-producing beta (β) cells.
View SourceAugust 11, 2010Provides Information
Special empowerment program to promote confidence in diabetic children
Teens are learning how to shred down the mountain and balance blood sugars in a special empowerment program called Riding on Insulin, taking place December 11, 2010, at The Canyons Resort in Park City. The day, led by Sean Busby—26-year-old professional snowboarder with type 1 diabetes—promotes courage and confidence and shows children with type 1 or type 2 they can overcome mental and physical challenges.
View SourceAugust 24, 2010Provides Information
Starting treatment early doubles chance of success for people with diabetes
The sooner people with diabetes start taking metformin, the longer the drug remains effective, according to a Kaiser Permanente study published in the March issue of Diabetes Care, a journal of the American Diabetes Association.
View SourceMarch 9, 2010Provides Information
STMicroelectronics and Debiotech Debut Disposable Insulin Jewel Pump at ADA Congress
Debiotech and STMicroelectronics today announced that they will publicly showcase their novel insulin "Jewel Pump" at the Debiotech stand at the American Diabetes Association 70th Scientific Sessions (June 25-29) in Orlando, Florida. Representing the most advanced use of microfluidic MEMS (Micro-Electro-Mechanical Systems) technology in diabetes treatment, the tiny device, for which FDA clearance is now pending, can be mounted on a disposable skin patch to provide continuous insulin infusion, enabling substantial improvements in the treatment efficiency and the quality of life of diabetic patients.
View SourceJune 23, 2010Provides Information
Structure of insulin's docking point identified
Walter and Eliza Hall Institute scientists have determined the structure of a previously unseen part of the insulin receptor, making possible new treatments for diabetes.
View SourceMarch 24, 2010Provides Information
Study compares risk with 2 diabetes drugs
In contrast to previous reports, the risks of the composite endpoint of heart attack, heart failure, both, or death were the same - about 4 percent - for patients taking the diabetes drugs rosiglitazone or pioglitazone, according to a study published in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.
View SourceAugust 24, 2010Provides Information
Study finds no link between diabetes drug rosiglitazone and increased rate of heart attack
The diabetes drug rosiglitazone has been under intense scrutiny since a 2007 study in the New England Journal of Medicine looked at more than 40 clinical trials and linked the drug's use with increased risk of heart attack and death from heart disease.
View SourceJune 29, 2010Provides Information
Study finds visually impaired people get insulin pen dosages right
Labels on the popular insulin pen used by people with diabetes warn against visually-impaired people using pens to measure out and administer their insulin dosage.
View SourceJuly 1, 2010Provides Information
Study highlights importance of individualized, patient-centered therapies
In an analysis from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, one of the largest studies of its kind to determine whether intensive blood glucose (sugar) control worked better than standard blood sugar control among diabetics, results show that the benefits of intensive therapy need to be balanced against the increase in total and cardiovascular disease-related death, increased weight gain, and high risk for severe low blood sugar.
View SourceJune 30, 2010Provides Information
Study: ONGLYZA and metformin improve HbA1c levels for adult patients with type 2 diabetes at 76-weeks
Bristol-Myers Squibb Company and AstraZeneca today announced results up to 76-weeks from a Phase 3 study of ONGLYZA(TM) as initial combination therapy with metformin, which produced long-term glycemic improvement (as measured by glycosylated hemoglobin level (HbA1c)) in treatment-naive adults with type 2 diabetes mellitus inadequately controlled on diet and exercise compared to treatment with an investigational 10 mg dose of saxagliptin or metformin alone. The study results also demonstrated that a higher number of patients were able to achieve the American Diabetes Association recommended HbA1c target of less than 7% with ONGLYZA and metformin as initial combination therapy, compared to monotherapy of either treatment at week 76. The initial combination of ONGLYZA and metformin, with or without pioglitazone rescue therapy, had similar adverse event (AE) rates compared to treatment with investigational saxagliptin or metformin alone. Results were presented at the 70th American Diabetes Association (ADA) Annual Scientific Sessions.
View SourceJuly 2, 2010Provides Information
Study points to potential new drug for type 2 diabetes
An experimental oral drug has lowered blood sugar levels and inflammation in mice with Type 2 diabetes, suggesting that the medication could someday be added to the arsenal of drugs used by millions of Americans with this disease, according to new research.
View SourceMarch 15, 2010Provides Information
Study reveals how galectin-3 carbohydrate-binding protein promotes angiogenesis
A new study describes how a carbohydrate-binding protein, galectin-3, promotes angiogenesis, the growth of new blood vessels. Targeting the protein, scientists identified two approaches that significantly reduced angiogenesis in mice.
View SourceAugust 16, 2010Provides Information
Study suggests link between metabolic disease, bone mass in mice
A new study by Johns Hopkins researchers has found that insulin, the sugar-regulating hormone, is required for normal bone development and that it may provide a link between bone health and metabolic disease, such as diabetes.
View SourceJuly 22, 2010Provides Information
Study uses Chinese wolfberries to improve vision imperfections caused by type-2 diabetes
A Kansas State University researcher is exploring the use of Chinese wolfberries to improve vision deficiencies that are common for type-2 diabetics.
View SourceMarch 30, 2010Provides Information
Summer Heat Is a Risk to Diabetes Patients
Survey Shows Many People With Diabetes Aren't Protecting Themselves From High Temperatures
View SourceJune 22, 2010Provides Information
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TCF7L2 protein may play important role in heart disease, other metabolic disorders: Researchers
Studying a protein already known to play an important role in type 2 diabetes and cancer, genomics researchers have discovered that it may have an even broader role in disease, particularly in other metabolic disorders and heart disease. In finding unsuspected links to other disease-related genes, the scientists may have identified future targets for drug treatments.
View SourceJuly 22, 2010Provides Information
Team approach to foot care lowers risk of amputation in diabetes
People with diabetic foot problems can lower their risk of leg amputation by relying on coordinated care that includes a podiatrist, according to a recent study. For instance, those with diabetes-related foot ulcers can reduce their risk of amputation by 31 percent.
View SourceAugust 19, 2010Provides Information
Technique Detects More Than 700 Antimicrobial-Resistance Genes
Using an advanced genetic screening technique, Agricultural Research Service (ARS) scientists and cooperators have detected, for the first time, more than 700 genes that give microbes like Salmonella and E. coli the ability to resist antibiotics and other antimicrobial compounds.
View SourceMay 27, 2010Provides Information
Teens With Diabetes Might Need Help in Transition to Adulthood
It is hard enough being a teenager -- or the parent of a teenager -- without also having to deal with type 1 diabetes. Keeping good control can be a problem when the responsibility for administering insulin and checking blood glucose levels passes from parent to child.
View SourceApril 6, 2010Provides Information
Tequila plant could help treat diabetes, osteoporosis
The agave plant, the key ingredient in Mexico's famous tequila, could help treat diabetes and osteoporosis, according to Mexican researchers.
View SourceApril 21, 2010Provides Information
Tethys Bioscience raises $33 million to drive market uptake of PreDx Diabetes Risk Score blood test
Tethys Bioscience, Inc., a privately held company, announced today that the company has recently raised $33 million, comprising $23 million of venture financing and a $10 million working capital loan. Participants in the venture financing included new investors Greenspring Associates, Inc. (formerly Montagu Newhall Associates, Inc.) and Paul Capital Investments, as well as current investors. The working capital loan was provided by Oxford Finance Corporation and Silicon Valley Bank.
View SourceJuly 21, 2010Provides Information
The protein GRP78 opens the door to life-threatening fungal infection
Mucormycosis is a life-threatening infection most commonly caused by a species of fungus known as Rhizopus oryzae. It occurs predominantly in individuals with diabetes, in particular those with the potentially life-threatening complication known as diabetic ketoacidosis.
View SourceMay 17, 2010Provides Information
The remarkable effects of fat loss on the immune system
Australian scientists have shown for the first time that even modest weight loss reverses many of the damaging changes often seen in the immune cells of obese people, particularly those with Type 2 diabetes.
View SourceApril 20, 2010Provides Information
Type 2 Diabetes May Have Link to Alzheimer's
Study Shows Insulin Resistance May Raise Risk of Brain Plaques Associated With Alzheimer's
View SourceAugust 25, 2010Provides Information
Type 2 diabetes medication rosiglitazone associated with increased cardiovascular risks and death
A new study published online today by JAMA shows that among patients age 65 years and older, rosiglitazone (a medication for treating Type 2 diabetes) is associated with an increased risk of stroke, heart failure, and all-cause mortality (death) when compared with pioglitazone (another medication for diabetes).
View SourceJune 28, 2010Provides Information
U
UF discovery could lead to better genetic screening for diabetes (w/ Video)
University of Florida researchers have identified a protein that affects how much insulin the body produces in people with a hereditary form of diabetes.
View SourceJune 8, 2010Provides Information
UnitedHealthcare Brings Preventative Medicine Into the Patient's Home With New Diagnostic Kits
UnitedHealthcare has announced that it will begin providing at-home screening kits to its customers, which will allow patients to determine their risk of heart disease and diabetes without visiting a laboratory. The kits, made by BioIQ, will require patients to extract a blood sample and mail it in to a lab, which will then analyze the levels of cholesterol, triglycerides, and blood glucose in the sample.
View SourceMay 14, 2010Provides Information
Unlocking the secrets of cellular energy holds promise for obesity, diabetes and cancer
A breakthrough on how cells regulate their energy is promising for clinical gains into diseases such as obesity, diabetes and cancer. Researchers at McGill University and University of Pennsylvania have uncovered new insights into how a protein known as the AMP-activated protein kinase, or AMPK, a master regulator of metabolism, controls how our cells generate energy. AMPK has previously been linked to a number of biological functions including cancer, diabetes, and proper immune function.
View SourceJuly 20, 2010Provides Information
Using genetic engineering techniques in pigs, scientists create new model of diabetes
The incidence of diabetes is rising worldwide. Using genetic engineering techniques in pigs, scientists at Ludwig-Maximilians-Universität (LMU) in Munich have created a new model of this metabolic disorder, which recapitulates many features of the disease, and promises to contribute significantly to improvements in diagnosis and therapy.
View SourceMarch 1, 2010Provides Information
USTPO awards Melior Discovery Notice of Allowance for type II diabetes and obesity drug candidate
Melior Discovery, Inc. announced today the United States Patent and Trademark Office (USTPO) has awarded a Notice of Allowance for a broad patent application covering the Company's use of MLR-1023 for, among other things, the treatment of type II diabetes and obesity. The patent will cover use of MLR-1023 for the treatment of type II diabetes, obesity and metabolic syndrome, including its use in combination with other compounds and as a component in other drugs.
View SourceJune 8, 2010Provides Information
USPTO grants Tethys key patent for PreDx Diabetes Risk Score test
Tethys Bioscience, Inc., a privately held company, announced today that the United States Patent and Trademark Office has granted the Company US Patent 7,723,050. The patent is directed to the company's groundbreaking PreDx™ Diabetes Risk Score (DRS) test and relates to proprietary methods for assessing the risk of developing a diabetic condition. Notably, this patent was issued following an accelerated review procedure which enables innovators to receive a final decision within 12 months of application. The issued patent is a major milestone for Tethys and has potential applicability to other Tethys products in development.
View SourceJune 24, 2010Provides Information
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Viral infection linked to juvenile diabetes
Researchers from Italy have found a statistically significant association between enteroviral infection and diagnosis of type-1 diabetes in children. They report their findings today at the 110th General Meeting of the American Society for Microbiology in San Diego, California.
View SourceMay 24, 2010Provides Information
Vivus Shares Plunge on FDA Panel Rejection of Diet Drug
Pharmaceutical company Vivus saw its shares drop by more than half on Friday after a Food and drug Administration panel declined to approve an experimental weight-loss drug called Qnexa, a drug that potentially could have been the company’s biggest seller.
View SourceJuly 16, 2010Provides Information
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Weight gain when there's a family history of type 2 diabetes
In the first study of its type, Australian researchers have shown that healthy people with a genetic predisposition to Type 2 diabetes gain more weight overeating over the short term than their non-genetically-prone counterparts.
View SourceMay 10, 2010Provides Information
WellDoc DiabetesManager System Gets US Green Light
WellDoc of Baltimore, MD won FDA clearance for its DiabetesManager System to be used by adults with type 2 diabetes in conjunction with their healthcare providers. The system aims to aid patients to adhere to proper diet and lifestyle in between visits to the doctor's office.
View SourceAugust 2, 2010Provides Information
Western food fuelling SE Asia diabetes boom: researchers
The growing popularity of Western junk food is fuelling a diabetes boom across Southeast Asia, Australian researchers warned on Wednesday.
View SourceJuly 7, 2010Provides Information
What affects the gastrointestinal symptoms in peritoneal dialysis patients?
Gastrointestinal symptoms are common in peritoneal dialysis patients. A research group in China investigated the gastrointestinal symptoms in peritoneal dialysis patients and explored the related factors. Eating dysfunction, reflux and indigestion were the most common gastrointestinal complaints. Patient with a history of corticosteroid therapy or taking more pills daily was more likely to develop gastrointestinal symptoms, while the better the residual renal function, the less likely the patient was to have these symptoms.
View SourceJune 24, 2010Provides Information
Why can surgical treatment improve type 2 diabetes mellitus?
Roux-en-Y gastric bypass (RYGB) is a commonly used surgical treatment for patients with morbid obesity. It significantly and persistently decreases the levels of blood glucose and glycosylated hemoglobin in 80-100 percent of type 2 diabetes mellitus (T2DM) patients. A study group from China found the possible mechanism of treating T2DM with RYGB surgery. This study has provided new basis for surgery to treat T2DM and explained why the post-surgical nesidioblastosis occurs in RYGB patients.
View SourceMay 12, 2010Provides Information
Why Does Diabetes Raise Cancer Risk?
More Questions Than Answers From Expert Panel on Diabetes, Cancer Link
View SourceJune 16, 2010Provides Information
Why fish oils work swimmingly against diabetes
Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insulin resistance.
View SourceSeptember 2, 2010Provides Information
Wireless health care for diabetes
Online communities could easily be used to offer people with chronic illnesses, such as diabetes , wireless healthcare services via mobile phones and the internet. The approach, outlined in the International Journal of Networking and Virtual Organisations, would reduce healthcare costs and empower many patients to manage their condition more effectively.
View SourceApril 1, 2010Provides Information
Wireless sensor watches blood sugar for diabetics
Researchers have developed an implantable sensor that measures blood sugar continuously and transmits the information without wires -- a milestone, they said, in diabetes treatment.
View SourceJuly 28, 2010Provides Information
Woman Ends Up in Coma After 'Overdosing' on Bok Choy
An 88-year-old Chinese woman, who was eating large amounts of bok choy in hopes of controlling her diabetes, ended up in a coma after ‘overdosing’ on the vegetable, according to a report in the New England Journal of Medicine.
View SourceMay 21, 2010Provides Information
Women With Gestational Diabetes: Common Glucose Test Also Accurately Predicts Adult-Onset Diabetes, Study Finds
A common test to diagnose gestational diabetes -- a temporary condition which can harm both mother and child if left untreated -- also has predictive power for Type II adult-onset diabetes, a new Tel Aviv University study finds.
View SourceJuly 8, 2010Provides Information
Women With Gestational Diabetes Have Increased Risk of Recurrence in Subsequent Pregnancies, Study Finds
There is an increased risk of recurring gestational diabetes in pregnant women who developed gestational diabetes during their first and second pregnancies, according to a Kaiser Permanente study appearing online in the American Journal of Obstetrics and Gynecology.
View SourceJuly 29, 2010Provides Information
Women with osteoporosis suffer more if they have previously broken a bone, say scientists
Osteoporosis is more common in women who have fractured bones when they were younger - and they experience a similar loss in health-related quality of life as those with arthritis, lung disease, diabetes and other chronic diseases.
View SourceAugust 19, 2010Provides Information
Wound Management Technologies' CellerateRX introduced at DFWG congress in South Africa
Wound Management Technologies, Inc. announced today that its new international distributor, Spiramed (Pty) Ltd, exhibited its advanced wound care collagen product, CellerateRX® last weekend at the DFWG (Diabetic Foot Working Group) congress in Cape Town and has already planned exhibitions at two additional upcoming conferences.
View SourceAugust 18, 2010Provides Information
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Your arteries may be suffering insulin resistance, too
In people with insulin resistance or full-blown diabetes, an inability to keep blood sugar levels under control isn't the only problem by far. A new report in the May issue of Cell Metabolism shows that our arteries suffer the effects of insulin resistance, too, just for entirely different reasons.
View SourceMay 4, 2010Provides Information
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