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| 14 Health - Schizophrenia Resources |
| Autism and schizophrenia: Scientists measure gene mutation rate |
| An international study led by University of Montreal scientists suggests family history may not be a good predictor of the presence of mutations predisposing to autism or schizophrenia. |
| View Source | August 26, 2010 | Provides Information |
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| Brain signs of schizophrenia found in babies |
| Schizophrenia is a debilitating mental disorder affecting one in 100 people worldwide. Most cases aren't detected until a person starts experiencing symptoms like delusions and hallucinations as a teenager or adult. By that time, the disease has often progressed so far that it can be difficult to treat. |
| View Source | June 21, 2010 | Provides Information |
| Brain to behaviour |
| How do you know where your keys are? Why do we develop habits and what influences our judgement? Throughout the Cardiff University, psychologists, behavioural geneticists and neurologists are working together to understand the fundamental mechanisms of learning and memory. Their work has implications for understanding brain function and changes as well as giving vital insight into neurological conditions such as Alzheimer's disease and schizophrenia. |
| View Source | August 23, 2010 | Provides Information |
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| CHMP adopts positive opinion on pending MAA for SYCREST sublingual tablets |
| Merck announced that the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion on the pending Marketing Authorization Application (MAA) for SYCREST® (asenapine) sublingual tablets. The CHMP has recommended that the European Commission grant a marketing authorization for SYCREST for the treatment of moderate to severe manic episodes associated with bipolar I disorder in adults. The CHMP did not support an indication for the treatment of schizophrenia. |
| View Source | June 25, 2010 | Provides Information |
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| Frontier research produces 3D neurological probe |
| European scientists have created a pioneering three-dimensional (3D) brain probing system that may provide new leads for understanding schizophrenia, Alzheimer’s disease and other serious brain conditions. Created under the NEUROPROBES ('Development of multifunctional microprobe arrays for cerebral applications') project, which received almost EUR 10 million under the 'Information society technologies' (IST) Thematic area of the EU's Sixth Framework Programme (FP6), the neurological breakthrough has already generated considerable interest and demand worldwide. |
| View Source | May 28, 2010 | Provides Information |
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| Genes found for schizophrenia are involved in brain signaling |
| By analyzing the genomes of patients with schizophrenia, genetics researchers have discovered numerous copy number variations—deletions or duplications of DNA sequences—that increase the risk of developing schizophrenia. Significantly, many of these variations occur in genes that affect signaling among brain cells. |
| View Source | May 10, 2010 | Provides Information |
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| How Darwin's little-known work impacts current schizophrenia, autism treatment (w/ Video) |
| Historical research by Peter J. Snyder, PhD, reveals more of Charles Darwin's thinking when he completed what may be the first example of a prospective "single-blind" study of human perception of emotional expression. Through scrutiny of Darwin's work, including previously unpublished handwritten notes on his experiments, Snyder explains how this early experiment has direct implications to current work today in the areas of schizophrenia, autism spectrum disorders and other neuropsychiatric conditions. |
| View Source | May 4, 2010 | Provides Information |
| How Psychiatric Risk Gene Disrupts Brain Development |
| Scientists are making progress towards a better understanding of the neuropathology associated with debilitating psychiatric illnesses like bipolar disorder and schizophrenia. New research, published in the July 15 issue of the journal Neuron, reveals mechanisms that connect a known psychiatric risk gene to disruptions in brain cell proliferation and migration during development. |
| View Source | July 16, 2010 | Provides Information |
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| Link Between Brain Chemical, Cognitive Decline in Schizophrenia Demonstrated |
| In one of the first such studies involving human patients with schizophrenia, researchers at UC Davis have provided evidence that deficits in a brain chemical may be responsible for some of the debilitating cognitive deficits -- poor attention, memory and problem-solving abilities -- that accompany the delusions and hallucinations that are the hallmarks of the disorder. |
| View Source | March 11, 2010 | Provides Information |
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| Molecular link between diabetes and schizophrenia connects food and mood |
| Defects in insulin function - which occur in diabetes and obesity - could directly contribute to psychiatric disorders like schizophrenia. |
| View Source | June 8, 2010 | Provides Information |
| Mouse Model May Provide Insight Into the Schizophrenic Brain |
| Schizophrenia is an incredibly complex and profoundly debilitating disorder that typically manifests in early adulthood but is thought to arise, at least in part, from pathological disturbances occurring during very early brain development. Now, a new study published by Cell Press in the February 25 issue of the journal Neuron, manipulates a known schizophrenia susceptibility gene in the brains of fetal mice to begin to unravel the complex link between prenatal brain development and maturation of information processing and cognition in adult animals. |
| View Source | March 1, 2010 | Provides Information |
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| Offspring of two psychiatric patients have increased risk of developing mental disorders |
| Offspring of two parents with schizophrenia or bipolar disorder appear more likely to develop the same illness or another psychiatric condition than those with only one parent with psychiatric illness, according to a report in the March issue of Archives of General Psychiatry. |
| View Source | March 1, 2010 | Provides Information |
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| Potential New Target for Schizophrenia Drugs Identified |
| Rockefeller University scientists have identified a protein that boosts the signaling power of a receptor involved in relaying messages between brain cells, a finding that suggests a new target for the development of treatments for schizophrenia and Parkinson's disease. The protein, called Norbin, directly interacts with a receptor for the neurotransmitter glutamate, which is critical to the process by which individual brain cells send messages to one another and plays a key role in learning and memory. |
| View Source | June 11, 2010 | Provides Information |
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| Schizophrenia Drugs Raise the Volume of a Key Signaling System in the Brain |
| All the major groups of medications for schizophrenia turn up the volume of a brain signal known to be muted in individuals with this psychiatric disorder -- a signal that also can be influenced by diet. "This is the first example of a common but specific molecular effect produced by all antipsychotic drugs in any biological system," scientists note in the current edition of ACS Chemical Neuroscience. |
| View Source | June 3, 2010 | Provides Information |