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174 Health - Stem Cell Resources $115 Million Stem Cell Research Center Planned in San Diego A new nonprofit institution plans to build a $115 million stem cell research facility in San Diego that would open by 2010. Open Open Tab April 21, 2008 Provides Information A A Comprehensive Protein Map of a Stem Cell Researchers have successfully identified over 5,000 proteins that are present in embryonic stem cells, tripling the size of previous results and in the process creating the largest quantified protein map to date. Open Open Tab April 7, 2008 Provides Information A stem cell type supposed to be crucial for angiogenesis and cancer growth does not exist? It is widely believed that tumor angiogenesis and cancer growth critically depend on circulating endothelial precursor cells, mobilized from the bone marrow. The recent study from researchers at the University of Helsinki, Finland, and Stanford University, US, now suggests that a stem cell type supposed to be crucial for blood vessel formation and cancer growth does not actually exist. Open Open Tab April 22, 2008 Provides Information Adult Stem Cell Application Effective In Treatment Of Peripheric Vascular Disease Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease. Open Open Tab January 28, 2008 Provides Information Adult Stem Cell Findings Offer New Hope For Parkinson's Cure New research provides evidence that a cure for Parkinson's disease could lie just inside the nose of patients themselves. Open Open Tab June 6, 2008 Provides Information Adult stem cell heart attack study updated Doctors are using patients' own bone marrow stem cells (progenitor cells) to treat the damage to cardiac muscle after a heart attack in a study at Emory University School of Medicine. Open Open Tab December 12, 2007 Provides Information Adult Stem Cells Aid Fracture Healing; UNC Study Lays Groundwork For Potential Treatments In an approach that could become a new treatment for the 10 to 20 percent of people whose broken bones fail to heal, researchers at the University of North Carolina at Chapel Hill have shown that transplantation of adult stem cells can improve healing of fractures. Open Open Tab June 18, 2008 Provides Information Adult Stem Cells Implanted By Catheter Rejuvinate Heart After Heart Attack A team of cardiologists at the University Hospital of Navarre, in collaboration with the Area of Cell Therapy at the same centre, and with the Gregorio Marañón Hospital in Madrid, have carried out clinical trials (phase II) on 50 patients in order to test the efficacy of adult stem sell transplants (in this case, myoblasts), in the heart of persons who have suffered a myocardial attack. Open Open Tab October 11, 2007 Provides Information Adult Stem Cells May Be Beneficial For Certain Cardiovascular Disorders And Autoimmune Diseases A review of previously published research suggests that stem cells harvested from an adult's blood or marrow may provide treatment benefit to select patients for some autoimmune diseases and cardiovascular disorders. Open Open Tab February 28, 2008 Provides Information Adult Stem Cells Reprogrammed In Their Natural Environment In recent years, stem cell researchers have become very adept at manipulating the fate of adult stem cells cultured in the lab. Open Open Tab June 30, 2008 Provides Information Advancing Stem Cell Gene Therapy reland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects. Open Open Tab December 16, 2007 Provides Information Advancing stem cell research and therapies while fully respecting the dignity of human life The following statement was released by Cardinal Justin Rigali of Philadelphia, chairman of the Committee for Pro-Life Activities at the United States Conference of Catholic Bishops. Open Open Tab November 21, 2007 Provides Information Ageing muscle 'given new vigour' Scientists have found a way to give old, tired muscles a new lease of life. Open Open Tab June 19, 2008 Provides Information Airlines Thwart Plans of 'Too Sick' Girl, 5, to Travel to China for Stem Cell Treatment Two airlines this weekend declined to fly Miranda Goranflo and her daughter Hailey to Beijing, where the 5-year-old was to receive stem-cell treatments for a rare fatal disease, the Courier-Journal reported. Open Open Tab June 30, 2008 Provides Information Another Major Stem Cell Advance Scientists at Advanced Cell Technology announced yesterday that they've derived colonies of stem cells from human embryos without doing any damage to those original embryos. Open Open Tab January 11, 2008 Provides Information Are Dual Cord Blood Banks The Answer To Increasing Stem Cell Demand? Demand for stem cells from cord blood is greater than supply. Two senior doctors, Professors Nicholas Fisk and Rifat Atun, analyse the UK's growing cord blood banking industry and the potential impact of a new bank that provides blood for both personal and public use. Open Open Tab March 22, 2008 Provides Information Artificial Membrane Sacks as Mini Stem Cell Labs At Northwestern University researchers discovered an interesting relationship between two molecules, in which their interaction forms a solid membrane that seems to be quite suited for creation of small sacs to host all kinds of cells in biological solutions, including possibly stem cells. Open Open Tab March 27, 2008 Provides Information Audit Ordered for California Stem Cell Agency California's top financial officer Tuesday ordered a top-to-bottom audit of the state's $3 billion stem cell institute, in the wake of reports that its chairman and one of its directors were involved in a violation of the agency's conflict-of-interest policy. Open Open Tab November 28, 2007 Provides Information B Blood Stem Cells Originate And Are Nurtured In The Placenta Solving a long-standing biological mystery, UCLA stem cell researchers have discovered that blood stem cells, the cells that later differentiate into all the cells in the blood supply, originate and are nurtured in the placenta. Open Open Tab March 6, 2008 Provides Information Blood Stem Cells Originate in the Placenta Blood stem cells, which later differentiate into all types of blood cells, originate and are nurtured in the placenta, a U.S. study finds. Open Open Tab March 7, 2008 Provides Information Bone Marrow Alternative: Stem Cells From Umbilical Cord May Be Used To Treat Hepatic Diseases Scientists from the University of Granada (Spain), in collaboration with the University of León, have confirmed that stem cells from human umbilical cord blood can be an appropriate therapy for the treatment of hepatic diseases such as hepatitis, and are therefore an effective alternative to bone marrow. Open Open Tab July 5, 2008 Provides Information Bone Marrow Stem Cell Release Regulated By Brain's Biological Clock Mount Sinai researchers have discovered that the release of blood stem cells from bone marrow is regulated by the brain through the cyclical human biological clock, via adrenergic signals transmitted by the sympathetic nervous system. These new findings point out that the harvest of stem cells for transplantation may be improved by timing it at the peak of their release. Open Open Tab February 7, 2008 Provides Information Bone repair using patient's stem cells comes closer Hitherto it has been difficult to induce adult human stem cells to produce bone, e.g. in order to repair bone tissue. Researchers at the University of Twente have shown that if the enzyme PKA is previously activated in the stem cells in the lab, following implantation this results in substantial bone formation. Open Open Tab May 26, 2008 Provides Information Brain Stem Cells Sensitive To Space Radiation Measures to protect astronauts from health risks caused by space radiation will be important during extended missions to the moon or Mars, say researchers in a paper currently online in Experimental Neurology. Open Open Tab December 12, 2007 Provides Information Brain Tissue Could Be Regenerated After Stroke By Inserting Microscaffolding And Stem Cells, Animal Study Suggests Strokes cause temporary loss of blood supply to the brain which results in areas of brain tissue dying - causing loss of bodily functions such as speech and movement. Neural Stem Cells offer exciting possibilities for tissue regeneration, but there are currently major limitations in delivering these cells to the brain. Open Open Tab April 10, 2008 Provides Information C California Snags Another Half Billion for Stem Cell Labs California's young stem cell agency has extracted promises of nearly $500 million in matching funds to help build what it calls one of the most ambitious medical-science lab-construction programs in the nation's history. Open Open Tab February 29, 2008 Provides Information Cancer Stem Cells May Be At The Root Of Brain Tumors Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer. Amongst the wildly dividing cells of a tumor, scientists have located cancer stem cells. Open Open Tab May 19, 2008 Provides Information Cardiac Stem Cell Therapy Closer To Reality Since the year 2000, much has been learned about the potential for using transplanted cells in therapeutic efforts to treat varieties of cardiac disorders. “Cardiac stem cell therapy involves delivering a variety of cells into hearts following myocardial infarction or chronic cardiomyopathy,” says Amit N. Patel, MD, MS, director of cardiac cell therapy at the University of Pittsburgh Medical Center and lead author of an overview and introductory article, Cardiac Stem Cell Therapy from Bench to Bedside. Open Open Tab December 30, 2007 Provides Information Cardiac stem cell therapy research Since the year 2000, much has been learned about the potential for using transplanted cells in therapeutic efforts to treat varieties of cardiac disorders. Open Open Tab December 30, 2007 Provides Information Cell therapies for diabetes, cancer Therapies using stem cell transplants are advancing promising treatments for such conditions as Alzheimer's Disease, neurological diseases and spinal cord injury, and heart disease. Open Open Tab March 21, 2008 Provides Information Cells Discarded From Womb Lining During A Woman's Period Are New Type Of Stem Cell The cells which thicken the womb wall during a woman's menstrual cycle contain a newly discovered type of stem cell, and could be used in the treatment of damaged and/or old tissue. Open Open Tab November 16, 2007 Provides Information Cloned stem cells successful in treating Parkinson's disease Scientists in the U.S. have had success in treating Parkinson's disease in mice by using cloned stem cells. Open Open Tab March 24, 2008 Provides Information Could Stem Cells Be Used To Cure Crohn's Disease? Scientists are investigating whether stem cells could be used to 're-boot' the immune system and provide a cure for Crohn's Disease. Open Open Tab December 3, 2007 Provides Information D Defense Department Sponsors Aggressive Stem Cell Research The US military is initiating a major research project to develop regenerative medicine technologies, that will hopefully allow for regrowth of tissues, skin, and body parts. Open Open Tab April 23, 2008 Provides Information Delivering Molecules via Biodegradable Microspheres Enhances the Efficiency and Purity of Stem Cell Differentiation Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. However, the inability of stem cells to efficiently develop into the desired specific cell type – such as muscle, skin, blood vessels, bone or neurons – now limits the potential clinical utility of this therapy. Open Open Tab April 10, 2008 Provides Information Discovery Could Help Reprogram Adult Cells To Embryonic Stem Cell-like State Harvard Stem Cell Institute (HSCI) and Massachusetts General Hospital (MGH) researchers have taken a major step toward eventually being able to reprogram adult cells to an embryonic stem cell-like state without the use of viruses or cancer-causing genes. Open Open Tab February 15, 2008 Provides Information Discovery Of Good -- And Bad -- Liver Stem Cells Raises Possibility Of New Treatment Many scientists believe up to 40 percent of liver cancer is caused by stem cells gone wild -- master cells in the organ that have lost all growth control. But, despite years spent looking, no one has ever found these liver "cancer stem cells" -- or even normal stem cells in the organ. Until now. Open Open Tab February 11, 2008 Provides Information Doctors Use 2-Year-Old Boy's Own Stem Cells to Treat Rare Cancer octors are hoping the umbilical cord blood banked by a toddler's parents at the time of his birth will save the 2-year-old from a rare and often fatal cancer. Open Open Tab January 7, 2008 Provides Information E Earliest Step In Human Development Revealed By Human Embryonic Stem Cell Research Researchers at Johns Hopkins have uncovered the molecular underpinnings of one of the earliest steps in human development using human embryonic stem cells. Their identification of a critical signal mediated by the protein BMP-4 that drives the differentiation of stem cells into what will become the placenta, will be published in the April issue of Cell Stem Cell. Open Open Tab April 11, 2008 Provides Information Elusive Pancreatic Stem Cells Found In Adult Mice Just as many scientists had given up the search, researchers have discovered that the pancreas does indeed harbor stem cells with the capacity to generate new insulin-producing beta cells. If the finding made in adult mice holds for humans, the newfound progenitor cells will represent "an obvious target for therapeutic regeneration of beta cells in diabetes". Open Open Tab January 24, 2008 Provides Information Embryonic Pathway Delivers Stem Cell Traits Studies of how cancer cells spread have led to a surprising discovery about the creation of cells with adult stem cell characteristics, offering potentially major implications for regenerative medicine and for cancer treatment. Open Open Tab May 21, 2008 Provides Information Embryonic pathway delivers stem cell traits Studies of how cancer cells spread have led to a surprising discovery about the creation of cells with adult stem cell characteristics, offering potentially major implications for regenerative medicine and for cancer treatment. Open Open Tab May 25, 2008 Provides Information Embryonic Stem Cells Are Identifiable By Appearance Alone Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait. Open Open Tab August 28, 2007 Provides Information Embryonic Stem Cells Could Help Overcome Immune Rejection Problems Speaking at the conference in Edinburgh, Dr Paul Fairchild from the University of Oxford will tell delegates that although tissues derived from ES cells succumb to rejection, they have an inherent immune-privilege which, if exploited, could have far reaching implications for the treatment of conditions such as diabetes, heart attacks and Parkinson's. Open Open Tab April 13, 2008 Provides Information Engineers Use Blood's Hydrodynamics To Manipulate Stem, Cancer Cells A tiny, implantable device has pulled adult stem cells out of a living rat with a far greater purity than any present technique. Open Open Tab January 28, 2008 Provides Information Enzyme plays key role in cell fate The road to death or differentiation follows a similar course in embryonic stem cells, said researchers at Baylor College of Medicine in Houston in a report that appears online in the journal Cell Stem Cell. Open Open Tab June 5, 2008 Provides Information G Gene Directs Stem Cells To Build The Heart Researchers have shown that they can put mouse embryonic stem cells to work building the heart, potentially moving medical science a significant step closer to a new generation of heart disease treatments that use human stem cells. Open Open Tab July 3, 2008 Provides Information Genetic Selection Of Target Stem Cell Populations Human embryonic stem cells can be genetically manipulated to help select out desirable cell types, according to a University of Nottingham study published online in Molecular Therapy. Open Open Tab December 2, 2007 Provides Information Germany eases law on stem cells The German parliament has voted to ease restrictions on embryonic stem cell research, which is controversial on ethical grounds. Open Open Tab April 11, 2008 Provides Information Geron Corporation awarded UK grant funding for human embryonic stem cell research Geron Corporation announced today two grant awards to the University of Edinburgh from the UK Stem Cell Foundation, with funding from the Medical Research Council and Scottish Enterprise. Open Open Tab May 6, 2008 Provides Information Growing Stem Cells and Other Tissue in the Laboratory Like they Grow in the Human Body Scientists have developed unique technology to grow stem cells and other tissue in the laboratory in conditions similar to the way they grow in the human body. Open Open Tab September 19, 2007 Provides Information H Heart Derived Stem Cells Develop Into Heart Muscle Dutch researchers at University Medical Center Utrecht and the Hubrecht Institute have succeeded in growing large numbers of stem cells from adult human hearts into new heart muscle cells. A breakthrough in stem cell research. Until now, it was necessary to use embryonic stem cells to make this happen. Open Open Tab April 23, 2008 Provides Information How Embryonic Stem Cells Develop Into Tissue-specific Cells Demonstrated While it has long been known that embryonic stem cells have the ability to develop into any kind of tissue-specific cells, the exact mechanism as to how this occurs has heretofore not been demonstrated. Open Open Tab May 13, 2008 Provides Information Human embryonic stem cells derived from preimplantation genetically diagnosed embryos A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis (PGD) to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. Open Open Tab November 16, 2007 Provides Information Human Embryonic Stem Cells Developed From Four-cell Embryo; World First May Lessen Ethical Concerns For the first time in the world scientists have succeeded in developing human embryonic stem cells (hESCs) from a single cell, or blastomere, of a 4-cell stage embryo, the 24th annual conference of the European Society of Human Reproduction and Embryology heard on July 9. Open Open Tab July 9, 2008 Provides Information Human pluripotent stem cells without human cloning Two major scientific papers published this week in Science and Cell unveil a proven way to generate patient-matched human pluripotent stem cells without human cloning, and without the use of human embryos or human or animal eggs. Open Open Tab November 21, 2007 Provides Information Human Skin Cells Reprogrammed Into Embryonic Stem Cells UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells without using embryos or eggs. Open Open Tab February 12, 2008 Provides Information Human Stem Cell Line Made Containing Sickle Cell Anemia Mutation Researchers at Johns Hopkins have established a human cell-based system for studying sickle cell anemia by reprogramming somatic cells to an embryonic stem cell like state. Publishing online in Stem Cells on May 29, the team describes a faster and more efficient method of reprogramming cells that might speed the development of stem cell therapies. Open Open Tab May 31, 2008 Provides Information Human Stem Cells Aid Stroke Recovery In Rats Neural cells derived from human embryonic stem cells helped repair stroke-related damage in the brains of rats and led to improvements in their physical abilities after a stroke. Open Open Tab February 20, 2008 Provides Information Human Stem Cells Show Promise Against Fatal Children's Diseases Scientists have used human stem cells to dramatically improve the condition of mice with a neurological condition similar to a set of diseases in children that are invariably fatal, according to an article in the June issue of the journal Cell Stem Cell. Open Open Tab June 5, 2008 Provides Information Human stem cells show promise against fatal children's diseases Scientists have used human stem cells to dramatically improve the condition of mice with a neurological condition similar to a set of diseases in children that are invariably fatal, according to an article in the June issue of the journal Cell Stem Cell. Open Open Tab June 4, 2008 Provides Information Human-animal embryo ruling due Regulators are due to make a decision whether to allow human-animal embryos to be created and used for research. Open Open Tab September 4, 2007 Provides Information I Identification Of A Novel Neural Stem Cell Type Researchers from the Sloan-Kettering Institute, led by Dr. Lorenz Studer, have discovered a novel type of neural stem cell, which has a broader differentiation potential than previously identified neural stem cells. Open Open Tab January 16, 2008 Provides Information Improprieties revealed at California Stem Cell Institute More apparent conflict of interest violations in applications for research grants in California's $6 billion stem cell program were revealed and the Foundation for Taxpayer and Consumer Rights (FTCR) called for all the tainted applications to be rejected. Open Open Tab December 10, 2007 Provides Information Incontinence Treatment: Muscle-derived Stem Cells Prove Effective In Reparing Sphincter Damage To Restore Continence Transplantation of muscle-derived stem cells may provide a safe and effective treatment for patients suffering from urinary incontinence following a surgical procedure. Two studies presented at the 103rd Annual Scientific Meeting of the American Urological Association (AUA), show that patients with incontinence resulting from iatrogenic sphincter damage may benefit from this therapy. Researchers are from Germany and Austria. Open Open Tab May 17, 2008 Provides Information L Leukemia Stem Cells Identified Stem cell researchers at UCLA have identified a type of leukemia stem cell and uncovered the molecular and genetic mechanisms that cause a normal blood stem cells to become cancerous. Open Open Tab May 27, 2008 Provides Information M Making Skin Cells Into Stem Cells Minus the Cancer Shinya Yamanaka, leader of one of two research groups responsible for turning skin cells into embryonic stem cell equivalents, has duplicated his breakthrough without using a gene that made the new cells cancerous. Open Open Tab November 30, 2007 Provides Information Many Paths, Few Destinations: How Stem Cells Decide What They'll Be How does a stem cell decide what specialized identity to adopt -- or simply to remain a stem cell? A new study suggests that the conventional view, which assumes that cells are "instructed" to progress along prescribed signaling pathways, is too simplistic. Open Open Tab May 22, 2008 Provides Information Mature B Cells Reprogrammed To Stem-cell-like State Fully mature, differentiated B cells can be reprogrammed to an embryonic-stem-cell-like state, without the use of an egg according to a study published in Cell. Open Open Tab April 21, 2008 Provides Information Mature Mouse Cells Reprogrammed to Stem Cell-Like State Without using an egg, researchers have been able to reprogram certain mature cells back to an embryonic-stem-cell-like state, a new report says. Open Open Tab April 17, 2008 Provides Information Mechanism For Regulation Of Growth And Differentiation Of Adult Muscle Stem Cells Is Revealed During muscle regeneration, which is a natural response to injury and disease, environmental cues cause adult muscle stem cells (satellite cells) to shift from dormancy to actively building new muscle tissue. Open Open Tab December 10, 2007 Provides Information Mechanism That Controls Activation Of Stem Cells During Hair Regeneration Identified Researchers at the University of Southern California (USC) have identified a novel cyclic signaling in the dermis that coordinates stem cell activity and regulates regeneration in large populations of hairs in animal models. The signaling switch involves bone morphogenetic protein (Bmp) pathway, according to the study that will be published in the Jan. 17 issue of the journal Nature. Open Open Tab January 19, 2008 Provides Information Menstrual Blood: A Valuable Source Of Multipotential Stem Cells? Researchers seeking new and more abundant sources of stem cells for use in regenerative medicine have identified a potentially unlimited, noncontroversial, easily collectable, and inexpensive source -- menstrual blood. Open Open Tab April 24, 2008 Provides Information Method To Deliver Molecules Within Embryonic Stem Cells Improves Differentiation Embryonic stem cell therapies have been proposed for regenerative medicine and tissue replacement after injury or disease. Open Open Tab April 14, 2008 Provides Information Method To Duplicate Primitive Stem Cells And Prevent Cell Differentiation Discovered Research from the University of Southern California (USC) has discovered a new mechanism to allow embryonic stem cells to divide indefinitely and remain undifferentiated. Open Open Tab May 22, 2008 Provides Information Molecular Level Self Assembly Leads to Miniature Stem Cell Laboratories Imagine having one polymer and one small molecule that instantly assemble into a flexible but strong sac in which you can grow human stem cells, creating a sort of miniature laboratory. Open Open Tab March 28, 2008 Provides Information Molecule Prompts Blood Stem Cells To Help Repair Heart Damage In Animal Model Researchers at UT Southwestern Medical Center have for the first time used drug-treated blood stem cells to repair heart damage in an animal model, results that might point to methods for healing injuries from heart attacks or disease. Open Open Tab April 17, 2008 Provides Information Muscular Dystrophy: Reprogrammed Human Adult Stem Cells Rescue Diseased Muscle In Mice Scientists report that adult stem cells isolated from humans with muscular dystrophy can be genetically corrected and used to induce functional improvement when transplanted into a mouse model of the disease. Open Open Tab December 14, 2007 Provides Information N Nanofibres and Stem Cells Form Bone and May Bring a Revolution in Orthopedic Science Support and funding from StemLife Berhad (StemLife), enabled the study of the interaction of novel nanofibers with bone-forming stem cells. Open Open Tab November 9, 2007 Provides Information Nerve Cells Derived From Stem Cells And Transplanted Into Mice May Lead To Improved Brain Treatments Scientists at the Burnham Institute for Medical Research have, for the first time, genetically programmed embryonic stem (ES) cells to become nerve cells when transplanted into the brain. Open Open Tab June 26, 2008 Provides Information Neural Stem Cell Study Reveals Mechanism That May Play Role In Cancer These newborn neurons then migrate along the stem cell fibers up to the neocortex, the seat of higher cognitive functions. Open Open Tab September 11, 2007 Provides Information Neurologically Impaired Mice Improve After Receiving Human Stem Cells Scientists report a dramatic success in what may be the first documented rescue of a congenital brain disorder by transplantation of human neural stem cells. The research, published by Cell Press in the June issue of the journal Cell Stem Cell, may lead the way to new strategies for treating certain hereditary and perinatal neurological disorders. Open Open Tab June 5, 2008 Provides Information Nerve Cells Made from Stem Cells Successfully Transplanted Researchers at the Burnham Institute for Medical Research in La Jolla, CA have for the first time converted stem cells to nerve cells, and implanted them into mice. The transplantation and accommodation of these cells was successful, and the scientists did not get into the common problems associated with transplanted cells, such as resulting formation of tumors. Open Open Tab June 30, 2008 Provides Information New insight into factors that drive muscle-building stem cells A report in the January issue of Cell Metabolism, a publication of Cell Press, provides new evidence explaining how stem cells known as satellite cells contribute to building muscles up in response to exercise. Open Open Tab January 9, 2008 Provides Information New interventional radiology treatment shows promise for complications from bone marrow, stem cell tranplants The standard treatment to treat graft-versus-host disease (GVHD) after bone marrow or cord blood transplant is intravenous (IV) steroids that alter the immune response; however, it is not always effective and failure results in very high mortality. Open Open Tab March 19, 2008 Provides Information New Jersey Voters Reject Plan to Borrow $450 Million for Stem Cell Research New Jersey voters on Tuesday rejected borrowing $450 million to pay for stem cell research grants in the state for 10 years. Open Open Tab November 7, 2007 Provides Information New technique produces genetically identical stem cells Adult cells of mice created from genetically reprogrammed cells-so-called induced pluripotent stem (IPS) stem cells-can be triggered via drug to enter an embryonic-stem-cell-like state, without the need for further genetic alteration. Open Open Tab July 1, 2008 Provides Information New Technique Produces Genetically Identical Stem Cells Adult cells of mice created from genetically reprogrammed cells--so-called induced pluripotent stem (IPS) stem cells--can be triggered via drug to enter an embryonic-stem-cell-like state, without the need for further genetic alteration. Open Open Tab July 6, 2008 Provides Information New Technology Tests Maturity Of Stem Cells Stem cells can differentiate into 220 different types of body cell. The development of these cells can now be systematically observed and investigated with the aid of two new machines that imitate the conditions in the human body with unprecedented accuracy. Open Open Tab May 8, 2008 Provides Information New understanding of adult stem cell regulation Forsyth Institute scientists have discovered an important mechanism for controlling the behavior of adult stem cells. Open Open Tab August 3, 2007 Provides Information Newly Created Cancer Stem Cells Could Aid Breast Cancer Research In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as "queens," possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the "worker" cells that form the bulk of the tumor. Open Open Tab August 14, 2007 Provides Information Noninvasive molecular imaging technology helps track stem cells in tumors Using noninvasive molecular imaging technology, a method has been developed to track the location and activity of mesenchymal stem cells (MSCs) in the tumors of living organisms, according to researchers at the Society of Nuclear Medicine's 55th Annual Meeting. This ability could lead to major advances in the use of stem cell therapies to treat cancer. Open Open Tab June 16, 2008 Provides Information O Oosight Microscope Enables Embryonic Stem Cell Breakthrough A noninvasive, polarized light microscope invented at the Marine Biological Laboratory (MBL) played a crucial role in a recent breakthrough in embryonic stem-cell research aimed at developing medical therapies. Open Open Tab December 3, 2007 Provides Information Ovarian Cancer Stem Cells Identified, Characterized Researchers at Yale School of Medicine have identified, characterized and cloned ovarian cancer stem cells and have shown that these stem cells may be the source of ovarian cancer's recurrence and its resistance to chemotherapy. Open Open Tab April 18, 2008 Provides Information P Pfizer bankrolls a stem cell start-up Pfizer is bankrolling a biotech start-up that will concentrate on developing new stem cell therapies for eye disease. Scripps Research Institute's Martin Friedlander has undertaken animal studies that identified bone and blood-marrow stem cells that could repair damaged blood vessels in the eye. Open Open Tab June 24, 2008 Provides Information Pioneering Induction Of Bone Formation Using Embryonic Stem Cells Researchers at the University of Twente break new ground by successfully creating bone tissue "in vivo", using embryonic stem cells. They imitated bone formation in embryos and children, which uses cartilage as a template. This new approach appears to be a promising way of repairing bone defects. Open Open Tab May 17, 2008 Provides Information Post Brain Injury: New Nerve Cells Originate From Neural Stem Cells Most cells in the human brain are not nerve cells, but supporting cells (glial cells). They serve as a framework for nerve cells and play an important role in the wound reaction that occurs with injuries to the brain. Open Open Tab March 16, 2008 Provides Information Precancerous Stem Cells Can Form Tumor Blood Vessels Tumors require a blood supply to grow, but how they acquire their network of blood vessels is poorly understood. A new study here shows that tumor blood vessels can develop from precancerous stem cells, a recently discovered type of cell that can either remain benign or become malignant. Open Open Tab February 22, 2008 Provides Information Primate Embryonic Stem Cells Successfully Cloned Researchers at Oregon Health & Science University's Oregon National Primate Research Center have made a significant breakthrough in efforts to develop human stem cell therapies that may be used to combat numerous devastating diseases. Open Open Tab November 15, 2007 Provides Information Probe Shows Stem-Cell Lines Faked An already disgraced scientist lied about all of the stem-cell lines he claimed were matched to different patients through cloning.Dec. 29, 2005 Open Open Tab   Provides Information Protein In Embryonic Stem Cells Control Malignant Tumor Cells A protein that governs development of human embryonic stem cells (hESCs) also inhibits the growth and spread of malignant melanoma, the deadliest skin cancer, Northwestern University researchers have discovered. Metastatic melanoma, which develops from the transformation of skin pigment cells or melanocytes, has a death rate of more than 80 percent and a median survival of less than 7.5 months. Open Open Tab March 5, 2008 Provides Information Protein That Controls Hair Growth Also Keeps Stem Cells Slumbering Like fine china and crystal, which tend to be used sparingly, stem cells divide infrequently. It was thought they did so to protect themselves from unnecessary wear and tear. But now new research from Rockefeller University has unveiled the protein that puts the brakes on stem cell division and shows that stem cells may not need such guarded protection to maintain their potency. Open Open Tab January 24, 2008 Provides Information Public funding impacts progress of human embryonic stem cell research Bolstered by supportive policies and public research dollars, the United Kingdom, Israel, China, Singapore and Australia are producing unusually large shares of human embryonic stem cell research. Open Open Tab June 5, 2008 Provides Information Public Funding Impacts Progress Of Human Embryonic Stem Cell Research Bolstered by supportive policies and public research dollars, the United Kingdom, Israel, China, Singapore and Australia are producing unusually large shares of human embryonic stem cell research, according to a report from the Georgia Institute of Technology in the June 2008 issue Cell Stem Cell. Open Open Tab June 5, 2008 Provides Information Purified Stem Cells Restore Muscle In Mice With Muscular Dystrophy Researchers at the Joslin Diabetes Center have demonstrated for the first time that transplanted muscle stem cells can both improve muscle function in animals with a form of muscular dystrophy and replenish the stem cell population for use in the repair of future muscle injuries. Open Open Tab July 13, 2008 Provides Information R Repairing Tissue Damage: Scientists Uncover Potential To Control Adult Stem Cells Research presented at the UK National Stem Cell Network Annual Science Meeting in Edinburgh represents a step towards the use of Adult Stem Cells (ASCs) to repair damaged tissue. Speaking at the conference in Edinburgh, Professor Cay Kielty of the University of Manchester describes how she and her team have uncovered a messaging system that instructs ASCs to contribute to tissue repair in response to chemical signals in the body. Open Open Tab April 12, 2008 Provides Information Research funders ask public what they really think about stem cell research The UK's two biggest public funders of stem cell research have today launched a year-long national dialogue programme that aims to find out what the public really think about stem cell science. Open Open Tab November 27, 2007 Provides Information Researchers Link Early Stem Cell Mutation To Autism In a breakthrough scientific study published June 30 in the Proceedings of the National Academy of Sciences, scientists at the Burnham Institute for Medical Research have shown that neural stem cell development may be linked to Autism. Open Open Tab July 1, 2008 Provides Information Revolutionary Nanotechnology Based Technique for Stem Cell Nerve RegrowthTreatment of Parkinson's Disease and Spinal Cord Injury A Monash University PhD student has developed a new technique that could revolutionise stem cell treatment for Parkinson's disease and spinal cord injury. Open Open Tab February 6, 2008 Provides Information Role Of Tiny RNAs In Controlling Stem Cell Fate Identified Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) and the University of California, San Francisco have identified for the first time how tiny genetic factors called microRNAs may influence the differentiation of pluripotent embryonic stem (ES) cells into cardiac muscle. As reported in the journal Cell Stem Cell, scientists in the lab of GICD Director, Deepak Srivastava, MD, demonstrated that two microRNAs, miR-1 and miR-133, which have been associated with muscle development, not only encourage heart muscle formation, but also actively suppress genes that could turn the ES cells into undesired cells like neurons or bone. Open Open Tab March 9, 2008 Provides Information Ronin An Alternate Control For Embryonic Stem Cells Like the masterless samurai for whom it is named, the protein Ronin chooses an independent path, maintaining embryonic stem cells in their undifferentiated state and playing essential roles in genesis of embryos and their development. Open Open Tab June 28, 2008 Provides Information S Safer Stem Cells? A small California biotech company backed by billionaire John Tu claims to have created stem cells without destroying human embryos or introducing cancer-causing genes, in what could be a major step toward using these stem cells for human trials. Open Open Tab February 27, 2008 Provides Information Scientist who created Dolly says stem cells from skin fragments now the way to go The scientist who created Dolly the sheep says he is abandoning the cloning of human embryos in stem cell research. Open Open Tab November 19, 2007 Provides Information Scientists Create Cardiac Cells From Stem Cells Scientists from the McEwen Centre for Regenerative Medicine at the University of Toronto created mesoderm heart progenitor cells from embryonic stem cells. Such a progenitor line is responsible for the production of three main types of cardiac cells: cardiomyocytes, endothelial cells and vascular smooth muscle cells. Open Open Tab April 25, 2008 Provides Information Scientists Developing Transfusable Blood from Stem Cells One day blood donation may become a thing of the past. Scientists at the RIKEN BioResource Center in Tsukuba, Japan are developing stem cell techniques that could lead to growing red blood cells in vitro, possibly making blood donation obsolete. Open Open Tab May 23, 2008 Provides Information Scientists Identify And Repress Breast Cancer Stem Cells In Mouse Tissue By manipulating highly specific gene-regulating molecules called microRNAs, scientists at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue -- cells that are widely thought to give rise to cancer. Open Open Tab December 20, 2007 Provides Information Scientists make cloned embryos from skin cells Scientists in California say they have produced embryos that are clones of two men, a potential step toward developing scientifically valuable stem cells. Open Open Tab January 17, 2008 Provides Information Scientists Overcome Major Obstacles To Stem Cell Heart Repair Scientists at Imperial College London have overcome two significant obstacles on the road to harnessing stem cells to build patches for damaged hearts. Open Open Tab December 13, 2007 Provides Information Scientists produce stem cells from ordinary mouse skin cells Researchers in the United States say they have produced a stem cell made from ordinary mouse skin cells which they have coaxed into becoming three different types of heart and blood cells in mice. Open Open Tab May 1, 2008 Provides Information Seaweed Transformed Into Stem Cell Technology Engineers at Rensselaer Polytechnic Institute have transformed a polymer found in common brown seaweed into a device that can support the growth and release of stem cells at the sight of a bodily injury or at the source of a disease. Open Open Tab November 11, 2007 Provides Information Seaweed-based Scaffold to Shelter Stem Cells Investigators at Rensselaer developed a novel bio-molecular scaffold, designed to provide an optimum environment for stem cells to grow. Their source of inspiration? Seaweed. Open Open Tab November 21, 2007 Provides Information Secrets Of Cellular Signaling Shed Light On New Cancer Stem Cell Therapies By revealing the inner workings of a common cell-to-cell signaling system, University of Michigan biologists have uncovered new clues about mysterious and contentious creatures called cancer stem cells. Open Open Tab April 12, 2008 Provides Information Self-assembled Materials Form Mini Stem Cell Lab Imagine having one polymer and one small molecule that instantly assemble into a flexible but strong sac in which you can grow human stem cells, creating a sort of miniature laboratory. And that sac, if used for cell therapy, could cloak the stem cells from the human body's immune system and biodegrade upon arriving at its destination, releasing the stem cells to do their work. Open Open Tab March 31, 2008 Provides Information Skin cell cure for sickle cells Scientists say they have found a new weapon against the blood disease sickle cell anaemia - the skin. Open Open Tab December 7, 2007 Provides Information Skin transformed into stem cells Human skin cells have been reprogrammed by two groups of scientists to mimic embryonic stem cells with the potential to become any tissue in the body. Open Open Tab November 20, 2007 Provides Information Stem Cell Based Drug Delivery System Carnegie Mellon University's Stefan F. Zappe is using adult neural stem cells to develop a new stem cell-based drug delivery therapy that may ultimately help treat a variety of inherited genetic disorders like Hunter syndrome. Open Open Tab November 5, 2007 Provides Information Stem Cell Discovery Sheds Light On Placenta Development Researchers studying embryonic stem cells have explored the first fork in the developmental road, getting a new look at what happens when fertilized eggs differentiate to build either an embryo or a placenta. Open Open Tab June 11, 2008 Provides Information Stem Cell Division and Hair Loss Link Researchers out of Rockefeller University have discovered the protein which slows stem cell division, and, coincidentally, it is the same one that controls hair growth. As such, there is promise that this knowledge will help thinning people one day to sprout and blossom again. Open Open Tab January 25, 2008 Provides Information Stem cell hope for bone fractures UK scientists hope to mend shattered bones and damaged cartilage using a patient's own stem cells. Open Open Tab February 18, 2008 Provides Information Stem Cell Immortal Strand Hypothesis Refuted How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer? Open Open Tab August 31, 2007 Provides Information Stem Cell Lines Created From Poor Quality Embryos Discarded From Fertility Clinics Human embryos that are discarded every day as medical waste from in vitro fertilization (IVF) clinics could be an important source of stem cells for research, according to a team of researchers at Children's Hospital Boston. Some of the embryos created during IVF are deemed "clinically useless" because of imperfections, but a paper published in the January 27 online edition of Nature Biotechnology shows that it is possible to derive stem cell lines from these poor-quality embryos. Open Open Tab January 31, 2008 Provides Information Stem Cell Research Aims To Tackle Parkinson's Disease Scientists in Sweden are developing new ways to grow brain cells in the laboratory that could one day be used to treat patients with Parkinson's disease, an international conference of biologists organised by the European Science Foundation (ESF) was told recently. Open Open Tab January 19, 2008 Provides Information Stem cell research aims to tackle Parkinson's disease Scientists in Sweden are developing new ways to grow brain cells in the laboratory that could one day be used to treat patients with Parkinson's disease, an international conference of biologists organised by the European Science Foundation (ESF) was told last week. Open Open Tab January 21, 2008 Provides Information Stem cell research from an ethical point of view New Springer book debates the moral status of the human embryo with special regard to stem cell research and therapy. Open Open Tab July 1, 2008 Provides Information Stem cell researchers claim victory in battle with Church Scientists have today welcomed MPs' decision to allow them to create human-animal hybrids in order to harvest embryonic stem cells for research. Open Open Tab May 19, 2008 Provides Information Stem Cell Researchers Demonstrate Safety Of Gene Therapy Using Adult Stem Cells A new study by UC Davis researchers provides evidence that methods using human bone marrow-derived stem cells to deliver gene therapy to cure diseases of the blood, bone marrow and certain types of cancer do not cause the development of tumors or leukemia. Open Open Tab May 7, 2008 Provides Information Stem Cell Research Produces A Key Discovery For Fragile X Syndrome An important finding has been made by McMaster researchers about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects approximately one in 4,000 males and one in 6,000 females. Open Open Tab September 14, 2007 Provides Information Stem Cell Researchers Create Heart And Blood Cells From Reprogrammed Skin Cells Stem cell researchers at UCLA were able to grow functioning cardiac cells using mouse skin cells that had been reprogrammed into cells with the same unlimited properties as embryonic stem cells. Open Open Tab May 1, 2008 Provides Information Stem Cell Sifting Machine Developed Scientists at University of California, Irvine developed a new way to sort through stem cells based on their electric charge properties. Open Open Tab December 21, 2007 Provides Information Stem Cell Therapy Studies For Stroke, Cerebral Palsy Prepare For Clinical Trials Finding answers about optimal dosage and timing for stem cell therapy in adults with strokes and newborns with ischemic injuries is a goal of two new federally funded studies. Open Open Tab January 30, 2008 Provides Information Stem cell therapy restores muscle function in mice with muscular dystrophy Muscular dystrophy is a genetic disease that occurs when the cells can no longer regenerate after injury and there is no effective treatment for the disease. Open Open Tab January 21, 2008 Provides Information Stem Cell Transplantation Procedure Results In Long-term Survival For Amyloidosis Patients Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light chain (AL) Amyloidosis. Open Open Tab August 8, 2007 Provides Information Stem Cell Treatment Credited for Giving Boy, 2, His Sight Back Florida mother is amazed her son is gaining his vision back. Open Open Tab June 5, 2008 Provides Information Stem Cell Type Supposed To Be Crucial For Angiogenesis And Cancer Growth Does Not Exist? It is widely believed that tumor angiogenesis and cancer growth critically depend on circulating endothelial precursor cells, mobilized from the bone marrow. A new study from researchers at the University of Helsinki, Finland, and Stanford University now suggests that a stem cell type supposed to be crucial for blood vessel formation and cancer growth does not actually exist. Open Open Tab April 24, 2008 Provides Information Stem Cell-Like Cancer Cells Resistant To Standard Therapy, Responsive To Targeted Therapy A comparison of breast cancer biopsies before and after treatment show that a subset of cells, which have stem cell-like properties, are resistant to standard chemotherapy. Tumors treated with lapatinib, which inhibits a pathway important for self-renewal, retained a smaller fraction of these tumorigenic cells after therapy. Open Open Tab April 30, 2008 Provides Information Stem Cells And Cancer: Cancer Pathways That Also Control The Adult Stem Cell Population Speaking at the UK National Stem Cell Network Annual Science Meeting in Edinburgh, Professor Alan Clarke from Cardiff University has described his work to investigate a mechanism that normally drives adult stem cells to repair the intestine. Open Open Tab April 14, 2008 Provides Information Stem cells cloned from monkey eggs Gleaning stem cells from cloned monkey embryos, as a team of Oregon researchers has done, is an impressive step. But it probably won't lead to medical treatments any time soon. Open Open Tab November 14, 2007 Provides Information Stem Cells Found For The First Time In The Pituitary A team of researchers led by scientists at Cold Spring Harbor Laboratory have for the first time identified stem cells that allow the pituitary glands of mice to grow even after birth. They found that, in contrast to most adult stem cells, these cells are distinct from those that fuel the initial growth of this important organ. Open Open Tab April 30, 2008 Provides Information Stem cells halt nerve disease An injection of stem cells has been used to cure mice with a normally fatal nervous system condition. Open Open Tab June 4, 2008 Provides Information Genes That Control Embryonic Stem Cell Fate Identified Scientists have identified about two dozen genes that control embryonic stem cell fate. The genes may either prod or restrain stem cells from drifting into a kind of limbo, they suspect. The limbo lies between the embryonic stage and fully differentiated, or specialized, cells, such as bone, muscle or fat. Open Open Tab July 13, 2008 Provides Information Stem cells made to mimic disease Scientists have taken skin cells from patients with eight different diseases and turned them into stem cells. Open Open Tab April 7, 2008 Provides Information Stem Cells Might Contribute To Vascular Disease Physician-scientists believe that stem cells might play a harmful role in the body's reaction to trauma following common vascular surgery, like angioplasty. Open Open Tab May 20, 2008 Provides Information Stem Cells Show Power To Predict Disease, Drug Toxicity For the first time, scientists have used human embryonic stem cells to predict the toxic effects of drugs and provide chemical clues to diagnosing disease. Open Open Tab December 16, 2007 Provides Information Stem cells prompt cancer spread Dangerous changes in cancer cells which allow them to spread around the body could be triggered by the body's own stem cells, say US scientists. Open Open Tab October 3, 2007 Provides Information Stem cells to treat damaged eyes and a rare skin disorder Doctors and scientists in Italy have shown how stem cells can be used to treat damaged eyes and, in combination with gene therapy, a rare and debilitating skin disease. Open Open Tab October 22, 2007 Provides Information Stem Cells Show Promise For Treating Huntington's Disease Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington's disease -- a fatal disorder for which there is currently no cure or even a treatment to slow the disease. Open Open Tab September 26, 2007 Provides Information Stem Cells Make Bone Marrow Cancer Resistant To Treatment Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments. Open Open Tab January 14, 2008 Provides Information Stem cells make bone marrow cancer resistant to treatment Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments. Open Open Tab January 15, 2008 Provides Information Stem Cells May Gradually Replace Antirejection Drugs For Kidney Transplant Patients After a transplant surgery, anti-rejection drugs for the organ recipient are a must, but with prolonged use can have serious side effects, including infections, heart disease and cancer. Open Open Tab January 24, 2008 Provides Information Stem Cells Used To Try To Save Patient's Legs A Northwestern University Feinberg School of Medicine researcher has launched the first U.S. trial in which a purified form of subjects' own adult stem cells was transplanted into their leg muscles with severely blocked arteries to try to grow new small blood vessels and restore circulation in their legs. Open Open Tab January 23, 2008 Provides Information Stem Cells: The Role Of Cancer-initiating Cells In Diagnosis And Treatment Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. As scientists learn more their cancer-initiating properties, stem cells are emerging as potential therapeutic targets for many types of cancers. Open Open Tab April 21, 2008 Provides Information Stem-cell finding alters ethical controversy When University of Wisconsin-Madison researchers succeeded in reprogramming skin cells to behave like embryonic stem cells, they also began to redefine the political and ethical dynamics of the stem-cell debate. Open Open Tab November 21, 2007 Provides Information Stem-cell Therapies For Brain More Complicated Than Thought An MIT research team's latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought. Open Open Tab November 29, 2007 Provides Information T Test of maturity for stem cells Stem cells can differentiate into 220 different types of body cell. The development of these cells can now be systematically observed and investigated with the aid of two new machines that imitate the conditions in the human body with unprecedented accuracy. Open Open Tab May 6, 2008 Provides Information Test of maturity for stem cells Stem cells can differentiate into 220 different types of body cell. The development of these cells can now be systematically observed and investigated with the aid of two new machines that imitate the conditions in the human body with unprecedented accuracy. Open Open Tab May 7, 2008 Provides Information Testicle stem cell harvest plan A man's testicles might be a source of stem cells to help him fight serious diseases, US scientists have shown. Open Open Tab September 19, 2007 Provides Information Therapeutic Potential Of Cord Blood Stem Cells Enhanced With New Technology A CD26 Inhibitor increases the efficiency and responsiveness of umbilical cord blood for bone marrow transplants and may improve care for blood cancer patients according to research from Rush University Medical Center being presented at the 6th Annual International Umbilical Cord Blood Transplantation Symposium, June 6-7 in Los Angeles. Open Open Tab June 10, 2008 Provides Information Tissue Regeneration: New Source Of Heart Stem Cells Discovered Researchers at Children's Hospital Boston are continuing to document the heart's earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells. Open Open Tab June 23, 2008 Provides Information Toddler With Rare Cancer Saved by Frozen Stem Cells The life of a 2-year-old British girl has been saved after she received a transplant of frozen stem cells, according to a report in the Daily Mail. Open Open Tab February 6, 2008 Provides Information Turning On Adult Stem Cells May Help Repair Bone The use of a drug to activate stem cells that differentiate into bone appears to cause regeneration of bone tissue and be may be a potential treatment strategy for osteoporosis, according to a new report. Open Open Tab January 25, 2008 Provides Information U US team makes embryo clone of men US scientists say they have produced embryos that are clones of two men, in an attempt to produce patient-specific stem cells. Open Open Tab January 16, 2008 Provides Information W What Condition Could Stem Cells Help First? A- Loss of vision, B -- Spinal-cord injuries, C -- Limb Circulation. Open Open Tab July 7, 2008 Provides Information Widespread support for nonembryonic stem cell research The VCU Life Sciences Survey is the first poll to reflect the discovery reported internationally in November that human skin cells can be used to create stem cells or their near equivalents. Open Open Tab December 21, 2007 Provides Information