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1,912 Health - Cancer Resources

Bladder Cancer

Basal tumor cell marker could help physicians personalize care for patients with bladder cancer
Tumor cells collected during the removal of a cancerous bladder and - in some cases - transplanted into mice with weakened immune systems, could help physicians rapidly identify high-risk cancers, determine prognosis and refine the use of biomarkers to personalize care for patients with this common cancer, according to a study published online on Oct. 24, 2016, in Scientific Reports.
October 22, 2016
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Certain occupations may increase bladder cancer risk, study reveals
A new analysis of UK workers reveals that certain occupations may increase the risk of bladder cancer.
June 30, 2016
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Cold medicine could stop cancer spread, study shows
A nonsteroid anti-inflammatory drug used for treating colds suppresses the spread of bladder cancers and reduces their chemoresistance in mice, raising hopes of a future cure for advanced bladder cancers, report researchers.
October 17, 2016
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Drug based on malaria protein shows promise against treatment-resistant bladder cancer
A new study shows that a drug derived from a protein found in the malaria parasite stopped chemotherapy-resistant bladder cancer tumors growing in mice. the researchers say that the finding could lead to much-needed new treatments for cases of bladder cancer that do not respond to standard therapy.
April 20, 2017
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Low physical activity increases risk of bladder, kidney cancer
Most of us know that physical activity is good for us. But a new study shows that a chronic lack of physical activity can drastically increase the chance of developing cancer in the bladder and kidneys, and it suggests that engaging in more physical activity may reduce this risk.
May 25, 2017
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Low vitamin D levels linked to increased risk of bladder cancer
Vitamin D deficiency is associated with an increased risk of developing bladder cancer, according to a systematic review of seven studies. Though further clinical studies are needed to confirm the findings, the study adds to a growing body of evidence on the importance of maintaining adequate vitamin D levels.
November 7, 2016
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Nanopolymer PolyGPA can Detect Elusive Bladder Cancer Biomarker
Researchers have created a new technique to detect glycoproteins in biological fluids. the Purdue University team engineered an array they called polyGPA (polymer-based reverse phase glycoprotein array) and have shown proof-of-concept experiments in using it to detect the presence of glycoproteins associated with bladder cancer in patient urine samples.
December 5, 2016
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New Blue Light Cystoscopy with Cysview can provide accurate diagnosis of bladder tumors
MedStar Washington Hospital Center now offers Blue Light Cystoscopy with Cysview®, a new, FDA-approved technology used to pinpoint bladder tumors in patients with known or suspected bladder cancer.
July 20, 2016
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Pacific Edge announces commercial launch of Cxbladder Monitor in the U.S.
Breakthrough in clinical utility for urologists managing bladder cancer patients
December 14, 2016
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Uscan Ultrasound for Automatic, High Resolution Bladder Measurements
Signostics out of Bothell, Washington, is releasing its portable Uscan ultrasound system. It consists of a transducer connected to a tablet device, the two optimized to perform urologic visualizations.
August 10, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - A

A Groundbreaking Gene-Editing Therapy Eliminated Cancer in Two Infants
Two infants diagnosed with an aggressive and previously incurable form of leukemia are now in remission, after British doctors say they cured the babies using so-called "designer cells."
January 26, 2017
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A new way to reset gene expression in cancer cells shows promise for leukemia treatment
Scientists have discovered a potential new target for the treatment of leukemia that potentially could augment the activity of BET inhibitors, drugs currently in clinical trials. These therapies act on histones, DNA's packaging proteins, to reset gene regulatory programs that go awry in cancer.
March 7, 2017
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Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals
The discovery of a protein signature that is highly predictive of leukemia could lead to novel treatments of the leading childhood cancer, according to new study showing that competition among certain proteins causes an imbalance that leads to leukemia.
April 11, 2017
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Added benefit of idelalisib drug not proven for patients with CLL
Already in 2014, the German Institute for Quality and Efficiency in Health Care (IQWiG) examined in an early benefit assessment whether idelalisib offers advantages over the appropriate comparator therapy for patients with chronic lymphocytic leukaemia (CLL). According to the findings, an added benefit was not proven because the drug manufacturer had presented no suitable data.
July 6, 2016
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Additions to standard therapy do not improve progression-free survival in patients with multiple myeloma
Trial results being presented today during the 58th American Society of Hematology Annual Meeting and Exposition in San Diego suggest two therapies that are often added to standard therapy in patients with multiple myeloma do not improve rates of progression-free survival compared with the current standard course of treatment alone. the study is the largest randomized controlled trial of post-transplant th
December 6, 2016
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AML study correlates gene mutations with 34 disease subgroups
A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities. the findings might help guide mutation testing and treatment decisions in the future.
March 21, 2017
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Antibody breaks leukemia's hold, providing new therapeutic approach
Acute myeloid leukemia (AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers have discovered that a cell surface molecule known as CD98 promotes AML.
October 28, 2016
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Antibody drug conjugate could hold promise in improving treatment for childhood ALL
Researchers at The University of Manchester have discovered that a protein (5T4) found on the surface of cells contributes to chemotherapy resistance in the most common type of childhood leukaemia. Using a novel approach, early testing shows that targeting the protein with an antibody drug conjugate (ADC) could hold promise in improving treatment.
May 19, 2017
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As body mass index increases, so does spread of multiple myeloma
Obesity is believed to be a risk factor for many cancers, and each 5 kg/m2 increase in BMI is associated with an increase of 10 percent in cancer-related deaths, studies show. now researchers have shown that as body mass index increases, so does the growth and spread of the blood cancer multiple myeloma.
July 12, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - B

Best treatment option written in cancer's genetic script
Acute myeloid leukaemia study finds personalized therapy is possible
January 16, 2017
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Biotech Firm Halts 'Revolutionary' Cancer Treatment After Patient Deaths
Following the deaths of five patients, Juno Therapeutics has decided to pull the plug on an experimental cancer treatment that boosts the power of a patient's immune cells. the news comes just days after the company's rival, Kite Pharma, announced its success with a similar method, showing there's still hope for this potentially revolutionary gene therapy.
March 2, 2017
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Blocking critical molecule with therapeutic antibody could effectively reduce leukemia burden
Acute myeloid leukemia is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML.
October 27, 2016
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Blood disorders cost €23 billion to European economy
Healthcare costs per patient with blood cancers are two times higher than average cancer costs, due to long hospital stays and complex treatment and diagnosis, a new report outlines.
July 22, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - C

Cancer gene mutations can predict response to less intensive treatment in AML patients
Patients with the most lethal form of acute myeloid leukemia (AML) - based on genetic profiles of their cancers - typically survive for only four to six months after diagnosis, even with aggressive chemotherapy. But new research indicates that such patients, paradoxically, may live longer if they receive a milder chemotherapy drug.
November 23, 2016
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Cannabinoids used in combination with chemotherapy found to be effective in killing leukemia cells
New research has confirmed that cannabinoids - the active chemicals in cannabis - are effective in killing leukemia cells, particularly when used in combination with chemotherapy treatments.
June 5, 2017
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Cannabinoids used in sequence with chemotherapy are a more effective treatment for cancer, say experts
Cannabinoids - the active chemicals in cannabis - are effective in killing leukemia cells, particularly when used in combination with chemotherapy treatments, new research confirms.
June 5, 2017
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Childhood Cancer Death Rates Continue to Fall: CDC
Brain cancer supplants leukemia as the leading killer
September 16, 2016
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CHLA researchers receive TRP grant to study new way of combating relapsed ALL
Yong-Mi Kim, MD, PhD, of the Saban Research Institute of Children's Hospital Los Angeles, has been awarded a 3 year translational research program (TRP) grant from the Leukemia & Lymphoma Society to study a novel approach to eradicating minimal residual disease in patients with acute lymphoblastic leukemia (ALL).
November 10, 2016
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Clinical study seeks to examine new combination therapy for treating AML patients
A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.
March 7, 2017
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Combination of two drugs could be effective strategy to target T-cell lymphocytic leukemia
Researchers have determined that two Phase 1 drugs (CX-4945 and JQ1) can work together to efficiently kill T-cell acute lymphoblastic leukemia cells while having minimal impact on normal blood cells.
October 22, 2016
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Common drug for autoimmune disease may increase risk of myeloid neoplasms
Mayo Clinic researchers have found that azathioprine, a drug commonly used to treat autoimmune disease, may increase the risk of myeloid neoplasms. Myeloid neoplasms include a spectrum of potentially life-threatening bone marrow disorders, such as myelodysplastic syndromes and acute myeloid leukemia.
February 3, 2017
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Computer trained to predict which AML patients will go into remission, which will relapse
Researchers have developed the first computer machine-learning model to accurately predict which patients diagnosed with acute myelogenous leukemia, or AML, will go into remission following treatment for their disease and which will relapse.
February 9, 2017
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Crucial cutting enzyme maps sites of DNA damage in leukemias and other cancers
Researchers map detailed sites of DNA damage that lead to abnormal genetic rearrangements
June 15, 2017
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - D

Defective ribosomes linked to aggressive form of multiple myeloma
20 to 40 percent of the patients with multiple myeloma - a type of leukaemia - have a defect in the ribosome, the protein factory of the cell. These patients have a poorer prognosis than patients with intact ribosomes. at the same time, they respond better to a drug that already exists.
December 9, 2016
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Deficiency of tumor suppressor gene may allow brain cancer cells to survive outside niches
Astronauts survive in space by wearing high-tech space suits. But how do brain cancer cells thrive when they migrate to inhospitable sites within the brain?
November 14, 2016
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Discovery of an ape virus in an Indonesian rodent species
The gibbon ape leukemia virus is a medically important tool in cancer therapies. GALV is a retrovirus pathogenic to its host species, the southeast Asian lar gibbon (Hylobates lar) and thought to have originated from a cross-species transmission and may not originally be a primate virus at all.
August 26, 2016
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Discovery of signalling pathway could pave way for developing treatments targeting T-ALL leukaemia
Cooperation between Finnish and Chinese research groups has opened up new opportunities for developing treatments targeting aggressive acute lymphoblastic leukaemia (T-ALL).
September 2, 2016
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Disturbances in blood cell gene transcription may lead to leukemia
Researchers have succeeded in shedding light on the pathogenesis of DNA breakpoints that are associated with leukemia. a mechanism discovered in a recent study can explain up to 90% of DNA damages present in the most common type of leukemia in children.
July 20, 2016
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Doctors Successfully Treat Two Babies with Leukemia Using Gene-Edited Immune Cells
It'S a Promising Approach, But Still Needs a Lot More Research
January 27, 2017
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Drug Helps Some Kids With Rare Type of Leukemia
Dasatinib prolonged survival in chronic myeloid leukemia patients, study says
June 5, 2017
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - E

Early detection of leukemia patients' resistance to therapy
Researchers have made a world-first breakthrough in the early detection of patients' resistance to a common treatment for chronic myeloid leukemia.
July 28, 2016
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Elegant way of pinpointing how new drugs exert beneficial effects
Tested on a newly discovered target, candidate drug for leukemia, the method has broader application
July 5, 2016
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Engineered immune cells boost leukemia survival for some
Patients with low disease load had best outcomes in first long-term look
April 4, 2017
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - F

Fasting blocks a specific leukemia in mice
Fasting stops development of early stage leukemia, reverses mid-stage disease.
December 22, 2016
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Fasting kills cancer cells of most common type of childhood leukemia,study shows
Intermittent fasting inhibits the development and progression of the most common type of childhood leukemia, researchers have found.
December 12, 2016
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Formaldehyde exposure not linked to leukemia, research shows
Some scientific reports have a profound impact on government policy. Sometimes, however, there are significant shortcomings in the research - yet the policy impact continues. Critically analyzing scientific research that underlies regulatory decision making and generating new information to ensure decisions are based on sound science are crucial.
May 2, 2017
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - G

Gene Therapy Helps 2 Babies Fight Type of Leukemia
Tweaking T-cells from healthy donor allowed infants to reach remission, researchers report
January 25, 2017
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Gene Therapy Shows Promise for Aggressive Lymphoma
Over one-third of patients appeared disease-free 6 months after single treatment, report says
February 28, 2017
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Gene-Based Therapy May Thwart a Tough Blood Cancer
Researchers attempt to turn immune cells into unerring killers of multiple myeloma cells
June 5, 2017
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Genetic hallmarks of acute lymphoblastic leukemia subtype uncovered
Genetic changes underlying a type of B-precursor acute lymphoblastic leukemia have now been identified by a research team.
October 22, 2016
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German scientists develop new approach to prevent GvHD after bone marrow transplants
Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants. the researchers describe the successful application of their strategy in mice in "Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion," which will be published online August 15 ahead of issue in the Journal of Experimental Medicine.
August 16, 2016
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GSK and University of Leicester team up to develop novel drugs to treat blood cancer
A collaboration between the University of Leicester and global pharmaceutical company GlaxoSmithKline (GSK) has been established to discover and develop novel medicines to treat aggressive forms of blood cancer.
July 21, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - H

Halting lethal childhood leukemia
Scientists identify molecular therapy to prevent growth of pediatric leukemia
January 6, 2017
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Hematologist-oncologist to lead bone marrow transplantation program for treating blood-borne cancers
Hematologist-oncologist Ahmad Samer Al-Homsi MD, MBA, will lead a new bone marrow transplantation program at NYU Langone's Perlmutter Cancer Center for treating blood-borne cancers, including leukemia, lymphoma and multiple myeloma, and potentially utilize transplantation as an adjunct to immunotherapy for solid tumors. He also will investigate ways to reduce graft-versus-host disease (GvHD), in which immune cells in donated blood and marrow attack the tissues of a recipient.
April 10, 2017
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Herpes virus linked to most common type of childhood cancer
Newborns with congenital cytomegalovirus -- a common virus in the herpes family -- may have an increased risk of developing acute lymphocytic leukemia, according to new research. the study suggests the risk is even greater in Hispanic children.
December 14, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - I

Identical twins experience unimaginable cancer
Since the day they came home from the hospital in matching newborn monkey outfits, Zane and Zac Taylor have done everything together.
September 23, 2016
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Important signalling pathway for leukemia cells discovered
Enables development of new treatments
September 2, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - L

Leukemia cell movement gives clues to tackling treatment-resistant disease
New research is shedding light on how leukemia cells can survive cancer treatment, suggesting new possibilities for stopping them in their tracks.
October 17, 2016
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Leukemia drug combo is encouraging in early phase I clinical trial
In a Phase I study, 8 out of 12 patients with relapsed and/or chemotherapy refractory blood cancers responded to a combination of the chemotherapy drugs thioguanine and decitabine; some of the responders had relapsed after treatment with decitabine alone, report researchers.
December 5, 2016
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Low cost method for examining single leukemia cells could transform treatment
Leukemia is a disease in which each cell can exhibit different genetic traits, and now researchers have found a cheap way to examine the individual cells. the breakthrough could transform leukemia treatment, say scientists.
October 14, 2016
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Low-dose aspirin may cut breast cancer risk by a fifth
Taking low-dose aspirin at least three times per week may reduce women's risk of breast cancer by up to 20 percent, a new study suggests.
May 2, 2017
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - M

Metabolism harnessed to reverse aggressiveness in leukemia
Researchers have identified a new drug target for the two most common types of myeloid leukemia, including a way to turn back the most aggressive form of the disease.
May 17, 2017
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Molecular signature for aggressive brain tumor uncovered
A routine test can be used to identify which patients may require intensive clinical management and surveillance for aggressive brain tumors, new findings suggest.
November 10, 2016
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Monitoring cell fates
Scientists have been studying the factors influencing the development of different blood cells. Their research shows that certain molecular mechanisms are not as relevant as previously assumed. this finding helps to improve our understanding of diseases such as leukemia and anemia.
July 27, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - N

Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model
Researchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.
April 17, 2017
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Nanoparticles reprogram immune cells to fight cancer
A new study describes new method to transform immune cells, while inside the body, into leukemia-fighting powerhouses.
April 17, 2017
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New blood cancer study with 'outstanding' results
Research reveals 'transformative outcomes' for patients with chronic lymphocytic leukemia.
April 27, 2017
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New class of anti-cancer agents may be promising treatment for multiple myeloma
The research revealed that the majority of myelomas rely on a protein called MCL-1 to stay alive. Potential drugs that inhibit MCL-1, which are in pre-clinical development, may be a promising new treatment for multiple myeloma.
August 08, 2016
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New drug combination targets aggressive blood cancer
A pair of drugs that may be a one-two punch needed to help combat acute myeloid leukemia (AML), an aggressive blood cancer that kills nearly three-fourths of patients within five years of diagnosis, is the focus of a new multi-center clinical trial that will enroll patients at three sites across the U.S.
March 7, 2017
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New hope for more effective treatment of leukemia
Activation of a specific protein could lead to acute lymphoblastic leukemia
April 11, 2017
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New leukemia treatment outperforms standard chemotherapies
Researchers are working on a new treatment for an aggressive type of leukemia that outperforms standard chemotherapies.
June 8, 2017
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New microfluidic technique may provide patients with less painful test for multiple myeloma
Multiple myeloma is a cancer of the plasma cells, which are white blood cells produced in bone marrow that churn out antibodies to help fight infection. When plasma cells become cancerous, they produce abnormal proteins, and the cells can build up in bone marrow, ultimately seeping into the bloodstream.
April 4, 2017
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New NCCN Guidelines outline diagnosis, treatment strategies for myeloproliferative neoplasms
Myeloproliferative Neoplasms are a group of blood cancers characterized by significant symptoms and a high risk of transformation into acute leukemia. These cancers–Myelofibrosis, Essential Thrombocythemia, and Polycythemia vera (PV)–affect approximately 13,000, 134,000, and 148,000 patients in the United States, respectively.
September 23, 2016
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New signaling pathway for programmed cell death identified in leukemia cells
Inflammatory stimuli during programmed cell death trigger maturation of neighboring leukemia cells
July 14, 2016
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New study correlates 80 cancer-related gene mutations with 34 AML subgroups
A large, new study of adults with acute myeloid leukemia (AML) correlates 80 cancer-related gene mutations with five subtypes of AML, which are defined by the presence of specific chromosomal abnormalities. the findings might help guide mutation testing and treatment decisions in the future.
March 21, 2017
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New study sheds light on pathogenesis of DNA lesions present in leukemia
Researchers have succeeded in shedding light on the pathogenesis of DNA breakpoints that are associated with leukemia. a mechanism discovered in a recent study can explain up to 90% of DNA damages present in the most common type of leukemia in children.
July 20, 2016
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New test holds potential to revolutionise diagnosis of childhood leukaemia
Researchers at the University of Manchester have unlocked the potential of a new test which could revolutionise the way doctors diagnose and monitor a common childhood leukaemia.
August 17, 2016
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New treatment recommendations for a high-risk pediatric leukemia
Medical researchers have identified genetic alterations that can be used to guide treatment of pediatric acute megakaryoblastic leukemia, which has a dismal prognosis.
January 23, 2017
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New type of cancer therapy described
A new study has found that a new chemotherapy is effective against both pediatric and adult cancers, and that it allows other chemotherapies to more readily reach their targets.
July 27, 2016
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Novel discovery improves profiling of acute myeloid leukemia patients for targeted therapies
Researchers have identified a set of genes, including DNMT3A, that could potentially be used to predict clinical outcomes of patients who suffer from a type of Acute Myeloid Leukemia (AML) associated with an FLT3 internal tandem duplication (FLT3-ITD) mutation.
July 8, 2016
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Novel immunotherapy shows promise against AML in clinical trial
A new type of immunotherapy shows promise against cases of acute myeloid leukemia (AML) that recur after treatment or that never respond to therapy in the first place. a small clinical trial at Washington University School of Medicine in St. Louis provides evidence that the immune system's "natural killer" cells can be dialed up in the laboratory, trained to recall that activation and then effectively unleashed to destroy cancer cells in some patients.
September 21, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - O

Obesity-associated protein could be linked to leukemia development
Cancer researchers have found an obesity-associated protein's role in leukemia development and drug response which could lead to more effective therapies for the illness.
December 22, 2016
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Open chromatin profiling key to identifying leukemia cells of origin
Researchers have found a precise and reliable way -- whole-genome profiling of open chromatin -- to identify the kind of cell that leads to a given case of leukemia, a valuable key to cancer prognosis and outcome.
July 11, 2016
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Over 750 biomarkers identified as potentials for early cancer screening test
First comprehensive list of cancer blood biomarkers researched in last 5 years
August 1, 2016
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Overcoming immune suppression to fight against bovine leukemia
A newly developed antibody drug reactivates suppressed immune cells, decreasing the bovine leukemia virus (BLV) counts in an infected cow. The antibody could be applied to treat a variety of intractable infectious diseases in cows.
June 7, 2017
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - P

Personalized cell therapy combination achieves complete remission in CLL patients
Latest results from trial investigating CAR therapy to treat CLL
May 31, 2017
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Protein network signals found to drive myeloid leukemias
Researchers have uncovered how mutations in a protein network drive several high-risk leukemias, offering new prospects for novel therapies. An existing drug might be repurposed to treat these leukemias, and the new understanding of the molecular mechanisms at work may offer clues to other drugs yet to be developed.
June 14, 2017
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - R

Research findings could guide development of potent combination therapies for leukemia
New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia. In recent work published in Nature, they show it's possible to deactivate cellular programs involved in tumor growth by disrupting a protein that regulates genes.
March 7, 2017
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Research shows how TET2 protein loss can open door for mutations that drive blood cancers
Imagine this scenario on a highway: a driver starts to make a sudden lane change but realizes his mistake and quickly veers back, too late. other motorists have already reacted and, in some cases, collide. Meanwhile, the original motorist - the one who caused the problem - drives on.
April 25, 2017
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Research suggests common blood cancer could be prevented before it develops
A common symptomless condition can develop into the blood cancer myeloma, researchers have discovered. they found that changes in the bone marrow needed for the cancer to grow have already taken hold in the preceding condition, raising the possibility that early medical intervention could prevent this incurable type of cancer from taking root.
July 11, 2016
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Researchers develop new strategy to limit side effects of stem cell transplants
A new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants has now been developed by scientists.
August 15, 2016
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Researchers develop new test for early detection of patients' resistance to leukemia treatment
Australian researchers have made a world-first breakthrough in the early detection of patients' resistance to a common treatment for chronic myeloid leukemia.
July 28, 2016
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Researchers discover BRCA1 gene is key for blood forming stem cells
Researchers have found that the BRCA1 gene is required for the survival of blood forming stem cells, which could explain why patients with BRCA1 mutations do not have an elevated risk for leukemia. the stem cells die before they have an opportunity to transform into a blood cancer.
January 24, 2017
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Researchers discover how epigenetic lesion can lead to T-cell acute lymphoblastic leukemia
Researchers from the Epigenetics and Cancer Biology Program (PEBC) led by Dr. Manel Esteller at the Bellvitge Biomedical Research Institute (IDIBELL) have discovered how an epigenetic lesion can lead to T-cell acute lymphoblastic leukemia.
March 30, 2017
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Researchers find a new way to identify, target malignant aging in leukemia
Discovery involves secondary AML, which particularly afflicts older patients with poor prognoses
August 26, 2016
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Researchers find new way for early prediction of leukemic relapse
Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.
August 26, 2016
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Researchers find new way to prevent graft-versus-host disease after stem cell transplants
Through experimental work, an international team of researchers led by City of Hope's Defu Zeng, professor of Diabetes immunology and hematopoietic cell transplantation, believe they may have found a way to prevent graft-versus-host disease after stem cell transplants while retaining the transplants' positive effects on fighting leukemia and lymphoma.
April 18, 2017
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Researchers uncover new molecular causes of brain cancer and leukemia
A joint research published today in Nature Communications has shown new molecular causes of brain cancer and leukemia. this research provided insight into the effect of mutations of enzymes involved in the development of these cancers and potentially consider a personalized treatment to improve the therapeutic response.
September 14, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - S

Scientists detect gene networks likely to be shared by all CLL patients
Research, involving scientists and doctors at the University of Southampton and Royal Bournemouth Hospital, has identified a network of genes that are likely to be shared by all patients who have chronic lymphocytic leukaemia (CLL).
June 28, 2016
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Scientists discover new genetic variations linked to increased myeloma risk
Researchers have identified eight new genetic variations in the human genome that could be linked to an increased risk of developing myeloma. the findings provide additional evidence and build on existing research that suggests myeloma can run in families.
July 5, 2016
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Scientists find possible achilles heel of treatment resistant cancers
Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models. Researchers suggest that blocking the signaling proteins c-Fos and Dusp1 as part of combination therapy might cure several types of kinase-driven, treatment-resistant leukemia and solid tumor cancers.
March 19, 2017
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Scientists identify new genetic variations contributing to onset of APL
NUS study uncovers novel genetic alterations contributing to development of leukemia
July 27, 2016
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Scientists identify set of genes that could predict clinical outcomes in patients with FLT3-ITD AML
Novel discovery by NUS scientists improves profiling of AML patients for targeted therapies
July 8, 2016
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Simple, coordinated approach can improve chances of survival for high-risk AML patients
New research shows that quickly identifying patients with high-risk acute myeloid leukemia (AML), and speeding the process to find them a stem cell donor and performing the transplant earlier, can significantly improve their chances of surviving for at least two years after diagnosis without a relapse.
December 5, 2016
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Socioeconomic factors -- not race or ethnicity -- influence survival of younger patients with multiple myeloma
Advances in the treatment of multiple myeloma, a cancer that forms in a type of white blood cell, have led to improved survival predominantly among young and white patients, with less of an increase in survival observed in patients of other ethnicities. a new study indicates that this gap is mostly due to socioeconomic differences between whites and ethnic minorities, not race itself.
August 22, 2016
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Socioeconomic factors may contribute to survival of young, white patients with multiple myeloma
Advances in the treatment of multiple myeloma, a cancer that forms in a type of white blood cell, have led to improved survival predominantly among young and white patients, with less of an increase in survival observed in patients of other ethnicities. a new study indicates that this gap is mostly due to socioeconomic differences between whites and ethnic minorities, not race itself.
August 22, 2016
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Stem cell-based test predicts leukemia patients' response to therapy to help tailor treatment
Leukemia researchers have developed a 17-gene signature derived from leukemia stem cells that can predict at diagnosis if patients with acute myeloid leukemia (AML) will respond to standard treatment.
December 6, 2016
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Study compares arm measures to BMI for assessing nutritional status of leukemia survivors
Arm anthropometry is a simple method to determine if a person is overweight or obese, and because it can distinguish between fat and muscle mass, unlike body mass index (BMI), it is a valuable method for assessing muscle loss in long-term survivors of childhood cancer.
March 23, 2017
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Study finds new therapeutic target to prevent progression of rare blood cancer
In a laboratory study, Upstate Medical University researcher Golam Mohi, Ph.D., his graduate student Yue Yang, and colleagues, have found that the loss of gene EZH2 promotes the development of Myelofibrosis (MF) in mice. the findings create a new pathway for study into the cause of MF and provide new therapeutic targets to block the progression of this rare form of blood cancer.
October 7, 2016
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Study highlights role of CMV in patients with leukemia after bone marrow transplantation
Recent studies on a small number of patients with leukemia treated with bone marrow transplantation have suggested that the presence of the common cytomegalovirus (CMV) in patients or their donors may protect against relapse or even death after the transplant. a large international study published in the journal Blood, based on data from some 9,500 transplant patients in over 400 hospitals between 2003 and 2010 now shows the opposite.
June 29, 2016
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Study reports BV therapy may be curative in some Hodgkin lymphoma patients
Five-year survival data published online today in Blood, the Journal of the American Society of Hematology (ASH), suggest that the targeted therapy brentuximab vedotin may have cured some Hodgkin lymphoma patients whose disease has persisted despite receiving previous therapies.
July 19, 2016
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Study shows how increase in BMI contributes to multiple myeloma growth and progression
In a new study published in Cancer Letters, American University researchers show how, as body mass index increases, so does the growth and spread of the blood cancer multiple myeloma, which accounts for about 10 percent of all blood cancers in patients.
July 12, 2016
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Study uncovers novel genetic alterations contributing to development of leukemia
Novel genetic alterations contributing to development of leukemia have been discovered by a team of scientists. the findings from the international study involving about 220 newly diagnosed and relapse patient samples pave the way for development of new therapies, they say.
July 27, 2016
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Swedish researchers develop new, low-cost method to examine individual leukemia cells
Leukemia is a disease in which each cell can exhibit different genetic traits, and now Swedish researchers have found a cheap way to examine the individual cells. Reported in Nature Communications, the breakthrough could transform leukemia treatment.
October 14, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - T

Therapeutic Vaccine Promising Against a Leukemia
Made by combining immune cells, cancer cells, it's kept some study patients in remission for nearly 5 years
December 6, 2016
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Tracking down therapy-resistant leukemia cells
Scientists have succeeded in finding a small population of inactive leukemia cells that is responsible for relapse of the disease. now the way is paved for research into new therapies that prevent disease relapse by eliminating the remaining, so-called dormant leukemia cells.
December 14, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - U

Umbilical CBT more effective than MUD bone marrow transplants for leukemia patients
A University of Colorado Cancer Center study compared outcomes of leukemia patients receiving bone marrow transplants from 2009-2014, finding that three years post transplant, the incidence of severe chronic graft-versus-host disease was 44 percent in patients who had received transplants from matched, unrelated donors (MUD) and 8 percent in patients who had received umbilical cord blood transplants (CBT).
July 27, 2016
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Blood Cancers - Leukaemia, Lymphomas and Myeloma - W

Wistar scientists discover marker for PMN-MDSCs in the blood of cancer patients
Myeloid-derived suppressor cells are a population of immune cells that have been implicated in tumor resistance to various types of cancer treatment, including targeted therapies, chemotherapy and immunotherapy. Polymorphonuclear cells represent the largest population of MDSCs. However, fully understanding the biology and clinical importance of these cells has been hampered by a lack of markers that set them apart from normal neutrophils.
August 05, 2016
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Bone Cancer

A new animal model to understand metastasis in sarcomas
Researchers have developed a modified version of an orthotopic model to recreate the metastatic steps in Ewing sarcoma, the second most common bone tumor in children and adolescents. this new model may become a valuable experimental tool to analyze metastatic potential in different kinds of sarcomas.
August 30, 2016
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Nanoparticles Could be Used to Target Bone Cancers in Large Mammals
At the University of Illinois, an engineer teamed up with a veterinarian to test a bone cancer drug delivery system in animals bigger than the standard animal model, the mouse. they chose dogs -- mammals closer in size and biology to humans -- with naturally occurring bone cancers, which also are a lot like human bone tumors.
July 26, 2016
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Researchers identify possible pathway to reboot immune system after bone-marrow transplants
New research has shown how a cell surface molecule, Lymphotoxin ? receptor, controls entry of T-cells into the thymus, and as such presents an opportunity to understanding why cancer patients who undergo bone-marrow transplant are slow to recover their immune system.
August 25, 2016
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Scientists test nanoparticle drug delivery in dogs with osteosarcoma
At the University of Illinois, an engineer teamed up with a veterinarian to test a bone cancer drug delivery system in animals bigger than the standard animal model, the mouse. they chose dogs - mammals closer in size and biology to humans - with naturally occurring bone cancers, which also are a lot like human bone tumors.
July 25, 2016
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Scientists trace origin cell of bone, soft tissue tumors, test drug target
Scientists have discovered a type of cell surrounding blood vessels can also serve as a starting point for sarcoma, a form of cancer that occurs in bones and connective tissues.
July 14, 2016
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Brain Cancer - A

Artificial intelligence reveals mechanism behind brain tumor
Researchers have used computer modelling to study how brain tumors arise. the study illustrated how researchers in the future will be able to use large-scale data to find new disease mechanisms and identify new treatment targets.
September 19, 2016
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Brain Cancer - B

Brain cancer and leukemia: new molecular mechanisms decoded
New molecular causes of brain cancer and leukemia have been revealed by new research. this research provided insight into the effect of mutations of enzymes involved in the development of these cancers and potentially consider a personalized treatment to improve the therapeutic response.
September 14, 2016
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Brain cancer could be prevented with olive oil compound
The health benefits of olive oil are wide-ranging; studies have linked the fat to reduced risk of obesity and heart disease, as well as cognitive improvements. Now, new research suggests that olive oil may also help to prevent brain cancer.
June 5, 2017
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Brain cancer patients live longer wearing electric cap designed to zap tumors
After decade of stalled treatment improvements, cap is a modest, pricey step forward.
April 3, 2017
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Brain cancer: Study sheds light on unexpected link between glioma and blood sugar
Having high blood sugar or Diabetes is linked to a higher risk of developing most cancers. However, studies have found that brain cancers such as glioma are less common in people with Diabetes and high blood sugar. Now, a new study begins to shed light on this surprising link. Could it be, the researchers ask, that brain tumors have a strong effect on blood glucose levels?
May 4, 2017
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Brain Cancer - C

Caution needed for drugs in development for most common malignant pediatric brain tumor
Researchers have studied how a crucial cancer-related protein plays a role in one of the most aggressive forms of medulloblastoma, the most common malignant brain tumor of childhood.
March 21, 2017
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Cedars-Sinai surgeons use high-definition imaging device to map the brain during surgery
Cedars-Sinai neurosurgeons have begun using a high-definition imaging device to see inside the brain during surgery, allowing them to map safer pathways to reach and remove tumors.
December 9, 2016
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Cell of origin in childhood brain tumors affects susceptibility to therapy
Children that are diagnosed with the severe the brain tumor malignant glioma often have a very poor prognosis. Knowledge about how pediatric malignant glioma arises and develops is still limited. new findings show that in mice glioma development and glioma cell properties are affected by both age and the cell type from which the tumor has arisen. the tumor cell of origin was also important for the susceptibility of the tumor cells towards cancer drugs.
November 17, 2016
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Chemical engineers help nanoparticles better target brain tumors
Getting drugs into the brain by cloaking them within nanoparticles that can sneak through the blood-brain barrier has been the focus of a lot of nanotechnology research over the past few years. There's quite a bit of progress toward that goal, including some notable successes.
May 23, 2017
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Combined therapy approach could prove promising to treat brain cancer
A "combined therapy" approach to treating the most common form of brain cancer could prove promising, scientists say.
June 28, 2016
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Common nerve protein elevated in aggressive neuroblastomas
A protein produced by nerve cells appears to be elevated in the blood of those with an aggressive form of neuroblastoma. the finding could potentially lead to a prognostic test for the disease or be used to monitor its progress.
October 12, 2016
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Custom-tailored strategy against glioblastomas
Glioblastomas are incurable malignant brain tumors. Usually the patients affected survive for only a few months. In addition, every tumor is quite different, which makes treatment very difficult. Researchers have now developed a completely new method as the basis for creating custom-tailored, two-stage therapies.
September 23, 2016
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Brain Cancer - D

Depriving deadly brain cancer cells of cholesterol causes tumor regression in mouse models
Researchers at University of California San Diego School of Medicine, Ludwig Institute for Cancer Research and the Scripps Research Institute, with colleagues in Los Angeles and Japan, report that depriving deadly brain cancer cells of cholesterol, which they import from neighboring healthy cells, specifically kills tumor cells and caused tumor regression and prolonged survival in mouse models.
October 13, 2016
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Dogs help in breast carcinoma research
Cancer of the mammary glands in dogs is very similar to human breast carcinoma. For this reason, treatment methods from human medicine are often used for dogs. Conversely, scientific knowledge gained from canine mammary tumors may also be important to human medicine. Researchers were able to show how similar these tumors are in both dogs and humans.
June 6, 2017
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Brain Cancer - E

'Electric Cap' May Help Fight a Deadly Brain Tumor
Study found significant increase in survival 2 years after diagnosis
April 3, 2017
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Brain Cancer - G

Genome analysis helps keep deadly brain cancer at bay for five years
An analysis of a patient's deadly brain tumor helped doctors identify new emerging mutations and keep a 55-year old woman alive for more than five years, researchers report.
February 15, 2017
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Glowing tumors help surgeons cut out brain cancer with precision
An experimental cancer imaging tool that makes tumors glow brightly during surgery has shown promise again in a new clinical study, this time in patients with brain cancer. the fluorescent dye technique, originally developed by surgeons to treat lung cancer, illuminated brain tumors in real-time during surgery, helping physicians distinguish between healthy and cancerous tissue
November 16, 2016
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Going beyond genetics yields clues to challenging childhood brain cancer
Changes in the epigenetics suggest a prognostic marker for childhood ependymomas and similarities with DIPG tumors, report scientists.
November 23, 2016
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Graphene Sensor Detects Individual Brain Cancer Cells
A team of scientists at the University of Illinois at Chicago (UIC) managed to use graphene as a sensor capable of differentiating between healthy astrocyte brain cells and their glioblastoma doppelg㭧ers. the technique works on individual cells that are placed in contact with graphene, which is just a lattice of carbon only one atom thick.
January 5, 2017
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Brain Cancer - I

Immunotherapy for glioblastoma well tolerated; survival gains observed
Small, phase one trial of a dendritic cell vaccine supports further study in larger trials
April 14, 2017
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Immunotherapy, gene therapy combination shows promise against glioblastoma
In a new study, gene therapy deployed with immune checkpoint inhibitors demonstrates potential benefit for devastating brain cancer.
January 4, 2017
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Brain Cancer - K

Key controller of biological machinery in cell's 'antenna' discovered
A new discovery of a regulatory enzyme working at the primary cilium could lead to treatments for the brain tumor medulloblastoma, outlines a new report.
June 6, 2017
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Brain Cancer - L

Lack of 'editing' in microRNAs can potentially drive brain cancers
Scientists in the UK and India have observed a "significant" lack of 'editing' in microRNAs in brain tissue of brain cancer patients.
June 16, 2017
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Large-scale study finds genetic errors associated with brain cancer
Hundreds of thousands of people in the United States are living with a brain tumor. Gliomas are a particular category of malignant brain tumor that includes glioblastoma - a tumor with a low survival rate. new research uncovers genetic variants associated with an increased risk of glioma.
March 28, 2017
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Brain Cancer - M

MGH researchers discover regulators of gene expression programs in medulloblastoma
Massachusetts General Hospital (MGH) researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. In their report published online in Cancer Discovery, the team also identifies potential targets for future treatments.
February 24, 2017
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Molecule stops fatal pediatric brain tumor
Scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor. the tumor is always fatal and primarily strikes children under 10 years old.
February 27, 2017
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Brain Cancer - N

Neuroscientists pinpoint key gene controlling tumor growth in brain cancers
Discovery could result in more accurate prognoses, help fuel development of new treatments
March 9, 2017
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New approach to destroying deadly brain tumors
A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer, according to a study.
June 13, 2017
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New fluid makes ultrasound images easier to interpret during brain surgery
The fluid, which resembles brain tissue, makes ultrasound images easier to interpret during an operation. this will make it easier for surgeons to remove brain tumours more accurately.
February 22, 2017
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New hope in fight against aggressive, often hard to treat brain tumor
A potential way of stopping one of the most aggressive types of brain tumor from spreading has now been identified by researchers, which could lead the way to better patient survival. Glioblastoma is one of the most common types of malignant brain tumors in adults.
September 23, 2016
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New information on how brain cancer spreads
Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse. Researchers have identified a pathway by which cancer cells aggressively spread and grow in the brain, opening up new possibilities for treatment.
November 17, 2016
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New molecule may inhibit growth of aggressive pediatric brain tumor
Northwestern Medicine scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor. the tumor is always fatal and primarily strikes children under 10 years old.
February 27, 2017
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New MRI technique sheds technology's longtime limits
Since its emergence in the 1970s, magnetic resonance imaging (MRI) has given physicians a better look inside tissues, helping to diagnose maladies from brain tumors to internal bleeding to torn ligaments. a new technology creates images resolved enough to enable consistent diagnoses across populations for the first time.
August 16, 2016
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New treatment for glioblastoma multiforme
Medical researchers have developed a new pharmacological agent to treat glioblastoma multiforme (GBM), the deadliest brain cancer.
December 28, 2016
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Novocure's Second Generation Optune System for Glioblastoma now FDA Approved
Novocure, a company now headquartered on the Jersey Isle, has announced FDA approval of the second generation of its groundbreaking Optune system. the Optune delivers so-called Tumor Treating Fields (TTFields) that interfere with cell division, in a sense pausing the development of tumors that are otherwise extremely difficult to treat. When cells divide they create mitotic spindles, tiny strings that pull on chromosomes to pry them apart for duplication.
July 18, 2016
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Brain Cancer - O

Olive oil component may help prevent cancer developing in the brain
A compound found in olive oil may help to prevent cancer developing in the brain, a study shows.
June 2, 2017
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Olive oil nutrient linked to processes that prevent cancer in brain
A compound found in olive oil may help to prevent cancer developing in the brain, a study shows
June 2, 2017
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Brain Cancer - P

PID1 gene enhances effectiveness of chemotherapy on brain cancer cells
The gene PID1 enhances killing of medulloblastoma and glioblastoma cells, investigators have found. Medulloblastoma is the most commonly occurring malignant primary brain tumor in children; glioblastoma is the most commonly occurring malignant primary brain tumor in adults.
April 11, 2017
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Potential target for treatment of aggressive brain cancer identified
Researchers have discovered that the BCL6 protein could potentially be used as a marker to predict clinical outcomes of patients suffering from Glioblastoma Multiforme (GBM), the most malignant cancer of the brain.
June 7, 2017
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Precision medicine advances pediatric brain tumor diagnosis and treatment
Largest study to date finds genomic sequencing and copy number analysis can provide vital information
January 19, 2017
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Promising new strategy to attack the most lethal brain tumor in children
Researchers have revealed new insight into how the most deadly pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG), may develop. they also have identified a compound that targets the "on" switch for cancer-promoting genes, which resulted in shrinking tumor size and increased survival in an animal model of DIPG. Preparations for a clinical trial are now under way.
March 7, 2017
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Brain Cancer - R

Radiation therapy critical to treating brain tumors, but linked to significant adverse effects
Radiation therapy (RT) using high-energy particles, like x-rays or electron beams, is a common and critical component in successfully treating patients with brain tumors, but it is also associated with significant adverse effects, such as neuronal loss in adjacent healthy tissues.
June 9, 2017
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Radiation therapy vital to treating brain tumors, but it exacts a toll
Researchers say treatment alters neural networks and may cause long-term cognitive impairment
June 9, 2017
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Researchers develop new approach to build better blood-brain barrier model
Delivering drugs to the brain is no easy task. The blood-brain barrier -a protective sheath of tissue that shields the brain from harmful chemicals and invaders - cannot be penetrated by most therapeutics that are injected into a person's blood stream. But for treating diseases of the central nervous system and cancers such as glioblastoma, it's essential to get drugs across this barrier and deliver them to where they are needed most.
June 6, 2017
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Researchers discover new combination therapy strategy for brain, blood cancers
A new potential strategy to personalize therapy for brain and blood cancers has now been discovered by researchers.
February 28, 2017
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Researchers discover potential new target for treating glioblastoma
Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research.
January 24, 2017
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Researchers identify genetic mutations that predict better prognosis for neuroblastoma patients
The collaborative work, in which UPV/EHU and Achucarro Center researchers have participated, has served to identify some genetic mutations that will help to improve the treatment of this disease
May 19, 2017
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Researchers identify pathway that helps cancer cells to aggressively spread in the brain
Glioblastoma multiforme remains the most common and highly lethal brain cancer and is known for its ability to relapse. Researchers at the University of Texas MD Anderson Cancer Center have identified a pathway by which cancer cells aggressively spread and grow in the brain, opening up new possibilities for treatment.
November 17, 2016
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Researchers kill brain cancer in mice with combination immunotherapies
A combination of drugs known as SMAC Mimetics and immune checkpoint inhibitors amplifies kill rates of cancer tumor cells in laboratory testing.
February 15, 2017
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Researchers report high response rate with single drug in phase I/II trial of paediatric brain cancer
A high response rate with a single drug in a phase I/II trial of paediatric brain tumour has set the stage for combination therapy with higher response and lower toxicity, researchers reported at the ESMO 2016 Congress in Copenhagen.
October 7, 2016
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Researchers slow glioblastoma by inhibiting tumor's PPARa receptor
One of the most remarkable features of glioblastoma is the metabolic reprogramming of cancerous cells, resulting in uncontrolled cell proliferation, hypoxic conditions and angiogenesis. Metabolic reprogramming enables tumor cells with a faster way to produce energy and form new membranes. for this and other reasons, glioblastoma is presently incurable and the affected patients have a poor outcome.
October 26, 2016
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Researchers use computer modelling to identify mechanism behind aggressive brain tumours
Researchers at Uppsala University have used computer modelling to study how brain tumours arise. the study, which is published today in the journal EBioMedicine, illustrated how researchers in the future will be able to use large-scale data to find new disease mechanisms and identify new treatment targets.
September 19, 2016
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Revolutionary approach for treating glioblastoma works with human cells
Researchers reach critical milestone for treating brain cancer
February 1, 2017
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Brain Cancer - S

Scientists discover enzyme that supports brain tumor growth
Researchers from the University of Texas MD Anderson Cancer Center in Houston have discovered that an enzyme helps brain tumors to grow. This finding offers the potential for new tumor treatment approaches.
May 26, 2017
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Scientists discover new biomarker to help determine aggressiveness of brain cancer
Researchers at UT Southwestern Medical Center have found a new biomarker for glioma, a common type of brain cancer, that can help doctors determine how aggressive a cancer is and that could eventually help determine the best course of treatment.
December 6, 2016
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Scientists discover promising target to treat highly aggressive brain tumor in infants
Using state-of-the-art gene editing technology, scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have discovered a promising target to treat atypical teratoid/rhabdoid tumor (AT/RT) -- a highly aggressive and therapy resistant brain tumor that mostly occurs in infants. T
April 11, 2017
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Scientists identify key defect in brain tumor cells
Researchers have identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.
February 2, 2017
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Scientists to test Zika virus on brain tumors
In a revolutionary first, scientists will test whether the Zika virus can destroy brain tumor cells, potentially leading to new treatments for one of the hardest to treat cancers.
May 19, 2017
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Smart drug targets the deadliest brain cancer for destruction
Scientists have designed a smart drug that only targets and kills GBM brain cancer cells. they have validated the compound that sensitizes GBM tumors to chemotherapy and results in a significant extension of life in an animal model.
November 21, 2016
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Some Brain Cancer Patients Have Radiation Options
Targeted approach appears to preserve mental functioning
July 26, 2016
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Some glioblastoma patients benefit from 'ineffective' treatment, researchers say
A subgroup of patients with a devastating brain tumor called glioblastoma multiforme benefited from treatment with a class of chemotherapy drugs that two previous large clinical trials indicated was ineffective against the disease, according to a study.
December 22, 2016
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Stereotactic radiosurgery could be more effective for patients with few metastatic brain tumors
Patients with three or fewer metastatic brain tumors who received treatment with stereotactic radiosurgery (SRS) had less cognitive deterioration three months after treatment than patients who received SRS combined with whole brain radiation therapy (WBRT). These findings are according to the results of a federally funded, Mayo Clinic-led, multi-institution research study published today in the Journal of the American Medical Association.
July 26, 2016
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'Sticky' nanoparticles promise more precise drug delivery for brain cancer
A Yale research team has found that by tinkering with the surface properties of drug-loaded nanoparticles, they can potentially direct these particles to specific cells in the brain.
May 22, 2017
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Studies help shed light on aggressive brain cancer
One study shows how glioblastomas quickly evolve, the other points to a promising type of therapeutic
May 3, 2017
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Study explains mechanisms behind glioblastoma influence on the immune system
Glioblastomas exert an influence on the microglia, immune cells of the brain, which causes them to stimulate cancer growth rather than attacking it. In a study, an international research team now explains the molecular mechanisms behind this action.
September 12, 2016
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Study finds microRNA let-7 plays key role in restricting neuroblastoma
Great strides have been made in treating neuroblastoma, the most common cancer in infants and toddlers. However, advanced cases are often fatal, and children who survive often face life-long physical and intellectual challenges related to their treatment. a study led by researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center, finds that a microRNA called let-7 plays a central role in curbing neuroblastoma and could focus efforts to find a targeted, nontoxic alternative to chemotherapy.
July 8, 2016
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Study reveals radiosurgery as viable treatment option for patients with resected brain metastases
For patients who have cancer that has metastasized to the brain, stereotactic radiosurgery (SRS) results in statistically comparable survival rates, reduced cognitive decline and better quality of life (QOL), compared to whole brain radiotherapy (WBRT), according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology (ASTRO).
September 23, 2016
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Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma
A study by a multidisciplinary team of researchers from the Saban Research Institute of Children's Hospital Los Angeles sheds further light on the role of the cytokine TGFݱ in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinatorial therapy to treat this cancer. Their data has been published online by the journal Clinical Cancer Research.
October 12, 2016
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Superfluid is now helping brain surgeons
A superfluid, which resembles brain tissue, makes ultrasound images easier to interpret during an operation. this will make it easier for surgeons to remove brain tumors more accurately, say researchers.
February 22, 2017
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Suppressing a DNA-repairing protein in brain could be key to treating aggressive tumors
Inhibiting a DNA-repairing protein in brain could be key to treating aggressive tumors, say researchers.
January 10, 2017
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Brain Cancer - T

Targeted radiosurgery better than whole-brain radiation for treating brain tumors
Study shows effectiveness of radiosurgery in controlling spread of brain cancer after surgery
February 16, 2017
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Therapy response in brain tumor cells is linked to disease prognosis
The brain tumor form glioblastoma is difficult to treat and has very poor prognosis. In a new study, scientists show that a type of stem cell in the tumor is present in different states, with different response to drugs and radiation. the results may open an avenue towards development of new treatment strategies designed to reverse therapy resistant cell states to more sensitive states.
December 13, 2016
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Three like-minded nonprofits collaborate to launch immunotherapy clinical trial for pediatric brain tumors
A Kids' Brain Tumor Cure Foundation, Solving Kids' Cancer and the Ty Louis Campbell (TLC) Foundation announce their joint financial support of a Phase 1 clinical trial to test the safety and efficacy of combination checkpoint inhibitors in the treatment of children with brain tumors.
August 25, 2016
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Two-in-one approach could help keep brain cancer in check
Glioblastoma is not only the most common form of brain cancer, it's also the most deadly. It affects people from around 40 years of age, and most people live for less than 2 years after aggressive therapy. now scientists report that a two-in-one approach could help keep brain cancer in check.
June 28, 2016
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Brain Cancer - U

UPV participates in Lumiblast project to develop novel treatments for hard-to-treat brain tumours
The Polytechnic University of Valencia (Universitat Polit碮ica de Val筣ia, UPV) is taking part in Lumiblast, a European project to develop an innovative approach to hard-to-treat brain tumours like glioblastomas.
October 14, 2016
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Brain Cancer - V

Vaccine Targeting Brain Tumors Seems Safe in Study
Combo therapy may also extend survival of glioblastoma patients, but more research needed
April 14, 2017
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Brain Cancer - W

Wearable Medical Device Boosts Brain Cancer Survival Rates
A wearable medical device has proven effective among patients with brain cancer.
April 10, 2017
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Breast Cancer - Numbers

3 Key Lifestyle Factors Can Lower Breast Cancer Odds
Stay trim, exercise and cut back on drinking, review findings suggest
May 23, 2017
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Breast Cancer - A

A new Drug and Nanoparticle Combination for Triple Negative Breast Cancer
A research team from the UK has developed a prospective new drug for confronting the highly aggressive "triple negative" breast cancer (TNBC), as well as a nanoparticle for delivering the drug directly into the cancer cells.
March 17, 2017
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ACCC introduces new online site to improve treatment and management of metastatic breast cancer
The Association of Community Cancer Centers (ACCC), partnered with the Avon Breast Cancer Crusade, the Cancer Support Community, and the Metastatic Breast Cancer Alliance (MBC Alliance), announced today the launch of a new online site designed to provide important educational information supporting patients diagnosed with metastatic breast cancer.
December 14, 2016
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Active ingredient of pungent substances slows growth of breast cancer cells
Capsaicin, an active ingredient of pungent substances such as chilli or pepper, inhibits the growth of breast cancer cells. this was reported by a team headed by the Bochum-based scent researcher Prof Dr Dr Dr habil Hanns Hatt and Dr Lea Weber, following experiments in cultivated tumour cells. In the journal "Breast Cancer - Targets and Therapy", the researchers from Ruhr-Universitat Bochum presented their findings together with colleagues from the Augusta clinics in Bochum, the hospital Herz-Jesu-Krankenhaus Dernbach and the Centre of Genomics in Cologne.
December 20, 2016
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Actor Gabrielle Union is on a Breast Health Mission
When life delivers a blow, actor Gabrielle Union doesn't sit around and stew. Instead, she takes action. Case in point: In 2005, she discovered that her close friend Kristen Martinez, then 31, had stage IV metastatic breast cancer. Without skipping a beat, Union rallied behind Martinez and her family to arrange treatment that could boost Martinez's chances of survival.
October 7, 2016
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Acupressure reduced fatigue in breast cancer survivors
Relaxing acupressure improved sleep, quality of life
July 7, 2016
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Acupuncture treatments after mastectomy help women cope with post-operative symptoms
Women who had acupuncture treatments after breast cancer surgery at Abbott Northwestern Hospital had a greater reduction in pain, nausea, and anxiety and were better able to cope on the first post-operative day compared with patients who had traditional care, according to a study published in the Oncology Nursing Forum in November.
November 30, 2016
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Adelaide researchers find new driver for breast density linked to cancer risk
Adelaide researchers are one step closer to breast cancer prevention after finding a new driver for breast density, an identified risk factor for breast cancer.
January 24, 2017
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African-American women twice as likely to choose autologous breast reconstruction, study shows
African American women undergoing mastectomy for breast cancer are more likely than white women to undergo autologous breast reconstruction using their own tissue, rather than implant-based reconstruction, reports a study in the August issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons.
August 02, 2016
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Angelina Jolie's Mastectomy and Gene Testing Rise
But, researchers did not find a corresponding increase in breast removal surgeries
December 14, 2016
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Aromatase inhibitors for breast cancer: Advantages over tamoxifen in early-stage disease
Longer survival, later recurrences/ Evidence for late-stage disease much poorer
December 29, 2016
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Artificial intelligence expedites breast cancer risk prediction
Researchers have developed an artificial intelligence (AI) software that reliably interprets mammograms, assisting doctors with a quick and accurate prediction of breast cancer risk. the AI computer software intuitively translates patient charts into diagnostic information at 30 times human speed and with 99 percent accuracy.
August 29, 2016
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Aspirin may cut breast cancer risk for women with diabetes
Researchers have long known that diabetes can increase a woman's risk of breast cancer. A new study, however, suggests that this risk could be significantly reduced with long-term use of low-dose aspirin.
June 12, 2017
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Breast Cancer - B

Background parenchymal enhancement of the breast not linked to increased risk of cancer
Women with a certain gene mutation are among the high-risk patients for breast cancer. with a magnetic resonance tomography (MRT) it is possible to detect tissue with measurable active blood supply which indicates an increased breast cancer risk.
July 25, 2016
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Bad Diet in Youth May Up Early Breast Cancer Risk
Study found an association, but didn't prove unhealthy foods caused disease
February 23, 2017
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Beating Breast Cancer But Still Paying a Price
Small study suggests few long-term survivors receive adequate symptom relief
December 14, 2016
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Big data brings breast cancer research forwards by 'decades'
Scientists have created a 'map' linking the shape of breast cancer cells to genes turned on and off, and matched it to real disease outcomes, which could one day help doctors select treatments, according to a study.
February 1, 2017
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Bioinformatics brings to light new combinations of drugs to fight breast cancer
In spite of the many drugs available to treat breast cancer, resistance continues to be a problem
December 20, 2016
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Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer
Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine (IRB Barcelona) to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer.
December 20, 2016
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Biomarker tests in breast cancer: Decision on chemotherapy remains difficult
Preliminary MINDACT results allow evaluation of the disadvantages of omitting chemotherapy; little specific information on advantages
December 29, 2016
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Blocking key nutrient uptake may be effective way of treating triple negative breast cancer
Cancer rewires the metabolism of tumor cells, converting them into lean, mean, replicating machines. But like Olympic athletes who rely on special diets to perform, tumor cells' amped-up metabolism can also make them dependent on specific nutrients for survival.
November 21, 2016
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Blood test that detects changes in tumor DNA predicts survival of women with advanced breast cancer
A blood test that spots cancer-linked DNA correctly predicted that most of those patients with higher levels of the tumor markers died significantly earlier than those with lower levels, results of a multicenter study of 129 women with advanced breast cancer show.
February 1, 2017
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Brain microenvironment makes HER2-positive breast cancer metastases resistant to treatment
Study identifies novel resistance mechanism, potential treatment strategy
May 24, 2017
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Breakthrough: Breast cancer relapse linked to fat metabolism
Although great strides have been made in the treatment of breast cancer, relapse is still a major issue that has defied investigation. a new study might pave the way to reducing relapse rates by identifying rogue cells earlier.
May 16, 2017
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Breast cancer cells found to switch molecular characteristics
Spontaneous interconversion between HER2-positive and HER2-negative states could contribute to progression, treatment resistance in breast cancer
August 24, 2016
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Breast cancer cells spread in an already-armed mob
Most tumor-driving mutations are carried from original malignancy, study suggests
May 10, 2017
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Breast cancer cells undergo stiffening state prior to becoming malignant, study shows
A study published now on Nature Communications shows that breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive. the discovery made by a research team led by Florence Janody, from Instituto Gulbenkian de Ciencia (IGC; Portugal), identifies a new signal in tumor cells that can be further explored when designing cancer-targeting therapies.
May 16, 2017
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Breast cancer cells: the importance of keeping silent
Researchers describe a repression mechanism active in hormone-dependent breast cancer cells for the first time. the repression complex of these cells silences genes related with cell proliferation and death, two key processes in cancer. the discovery contributes new knowledge on gene-silencing mechanisms and will help identify new targets for possible future treatments.
July 7, 2016
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Breast Cancer Deaths Increasing for Black Women
Researchers have known for years that African-American women die of breast cancer at higher rates than white women. now a new study finds that the rates vary from city to city and the disparity is getting worse, not better.
October 3, 2016
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Breast cancer drug dampens immune response, protecting light-sensing cells of the eye
The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice. the drug prevented immune cells from removing injured photoreceptors.
March 13, 2017
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Breast Cancer 'Immunotherapy' Helps Some
A minority of women with 'triple-negative' tumors responded to Tecentriq, but they responded well
April 3, 2017
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Breast cancer patient finds new hope with potentially revolutionary treatment
City of Hope patient Susan Young has had a remarkable response to a potentially revolutionary new treatment, a combination of the p53 cancer vaccine and a drug that blocks a specific cancer-aiding protein.
December 21, 2016
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Breast cancer patients could benefit from controversial hormone
An international team of researchers is tackling the controversy over what some scientists consider to be a 'harmful' hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments.
December 9, 2016
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Breast cancer patients who use social media express more satisfaction about treatment decisions
Women who engaged on social media after a breast cancer diagnosis expressed more deliberation about their treatment decision and more satisfaction with the path they chose, a new study from the University of Michigan Comprehensive Cancer Center finds.
July 29, 2016
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Breast Cancer Radiation May be Risky for Smokers
Long-term chances of heart attack, lung cancer higher for women who light up, study finds
March 29, 2017
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Breast Cancer Screening Less Likely in Minorities
More study is needed to understand the disparity, researchers say
December 16, 2016
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Breast cancer screening provides framework for radiologist-led bundled payment models, study reports
According to a new report by the Harvey L. Neiman Health Policy Institute, mammography may present an opportunity for the expanded use of bundled payments in radiology. the study, published online in the Journal of the American College of Radiology (JACR), reports that breast cancer screening provides a framework for radiologist-led bundled payment models, and can be implemented with different services included in the bundle depending upon a practice's specific patient panel.
August 19, 2016
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Breast cancer study predicts better response to chemotherapy
It is known from previous research that the ER-beta estrogen receptor often has a protective effect. a new study has found that this effect is more pronounced in patients that undergo chemotherapy.
December 14, 2016
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Breast Cancer Survivors and Life-Extending Therapy
Study estimates nearly 15,000 lives saved over decade if all who needed hormone treatment got it
February 2, 2017
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Breast cancer update: Sentinel node biopsy guidelines encourage 'less is more' approach
New recommendations from breast cancer experts on sentinel lymph node biopsy reinforce the most recent "less-is-more" guidelines for early-stage disease. But a researcher who helped create the guidelines said many surgeons still perform full lymph node dissection routinely.
December 13, 2016
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Breast cancer: a visual guide to self-examination
Monthly breast self-examination can help detect abnormalities or changes that may be signs of cancer.
April 12, 2017
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Breast cancer: Anatomy and early warning signs
Certain changes in the breast may be early signs of breast cancer. Knowing what these changes look like can help people access the right treatment, as soon as possible.
April 18, 2017
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Breast cancer: Study identifies a molecular mechanism of drug resistance in ER+ tumors
The majority of breast cancers are estrogen-receptor positive and often treated with anti-estrogen drugs such as tamoxifen. However, resistance to the hormone therapy eventually develops in a large number of patients, leaving them with few options. Now, new research reveals a molecular explanation for this type of drug resistance and could lead to new therapies and better treatment decisions for estrogen-driven breast tumors.
March 21, 2017
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Breast cancers found by mammography do not regress if left untreated
Breast cancers detected by mammography screening do not spontaneously disappear or regress if left untreated, according to a new study. the scientific findings contradict claims that many cancers found via mammography may simply "go away' if left undiscovered or untreated.
May 1, 2017
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Breast density matters in detection of breast cancer
Almost 8% of women have extremely high breast density, which can make it harder for health professionals to detect breast cancer on a screening mammogram. These women are also more likely to develop breast cancer in the future, research shows.
October 4, 2016
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Breast microbiome/bacterial differences identified between healthy, cancerous tissue
Researchers have identified evidence of bacteria in sterilely obtained breast tissue and found differences between women with and without breast cancer.
August 03, 2016
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Breast rashes: Which symptoms suggest cancer?
Rashes have a habit of attracting attention. the skin may react to a number of triggers with redness, swelling, itching, pain, roughness, or other symptoms.
April 26, 2017
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Breast thermography: Technology, benefits, and cancer signs
Breast thermography is a non-invasive and painless test, with no radiation involved. It can detect and monitor early warning signs of breast cancer.
April 17, 2017
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Breastfeeding for longer than 6 months can lower breast cancer mortality risk
A new study of women 20 years after undergoing surgery for primary breast cancer shows that breastfeeding for longer than 6 months is associated with a better survival rate. Among breast cancer survivors who breastfed for >6 months, both breast cancer mortality and overall mortality risk were less after 20 years, according to the study published in Breastfeeding Medicine, the official journal of the Academy of Breastfeeding Medicine published by Mary Ann Liebert, Inc., publishers.
August 31, 2016
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BU researcher receives grant to better understand breast cancer in African-American women
Why do African-American women die at a higher rate and experience more aggressive breast tumors than white women? Researchers from Boston University's Slone Epidemiology Center have received funding from the National Cancer Institute to explore this question. the new grant is based on the premise that having a better understanding of the biology of breast cancer in African-American women will lead to better prevention and treatment.
July 6, 2016
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BUSM researchers discover new pathway and protein involved in metastasis of breast cancer
Researchers have identified a new pathway and with it a protein, BRD4, necessary for breast cancer cells to spread.
November 15, 2016
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Breast Cancer - C

Cells from same cell bank lots may have vast genetic variability
Findings have implications for reproducibility of cell culture experiments, a foundation of scientific research
July 26, 2016
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Cheese may raise breast cancer risk, but yogurt could reduce it
Dairy foods have their pros and cons; though they are a good source of calcium, they can also be high in fat. When it comes to the effects of dairy foods on breast cancer risk, a new study finds that they can be just as conflicting.
March 1, 2017
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'Chemo Brain' and Breast Cancer Survivors
Altered thinking must be acknowledged as 'one of the difficulties of treatment,' specialist says
January 11, 2017
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Chemoresistance in breast cancer is related to varying tumor cell populations
Drug resistance could be overcome after a 'drug holidays' period
April 27, 2017
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Clinical trial to evaluate safety of palbociclib drug in African American women with breast cancer
The first clinical trial to test a newly approved breast cancer drug specifically in African American patients is now enrolling at Georgetown Lombardi Comprehensive Cancer Center and will begin soon at five other institutions in Washington, DC, Maryland, Alabama and new Jersey.
July 7, 2016
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Cognitive dysfunction in breast cancer patients linked to post-traumatic stress
Subtle cognitive dysfunction and decline in breast cancer patients was largely independent of chemotherapy but associated with cancer-related post-traumatic stress in a German multisite study.
May 4, 2017
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'Cold Caps' May Halt Breast Cancer Hair Loss
Devices reduce blood flow to hair follicles during chemotherapy treatments
December 9, 2016
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Columbia University Medical Center to evaluate Biocept's Target Selector platform to diagnose LM in breast cancer patients
Biocept, Inc., a leading commercial provider of clinically actionable liquid biopsy tests designed to improve the outcomes of cancer patients, announces that Columbia University Medical Center will conduct a study to evaluate the clinical utility of the Company's Target Selector™ platform to diagnose leptomeningeal metastases in patients with breast cancer.
December 30, 2016
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Computer accurately identifies and delineates breast cancers on digital tissue slides
Deep-learning network possible step toward automating biopsy slide analysis
May 10, 2017
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Controversial hormone could fight against recurring breast cancers
An international team of researchers involving the University of Adelaide is tackling the controversy over what some scientists consider to be a "harmful" hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments.
December 9, 2016
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Breast Cancer - D

Depression drug can alleviate joint pain in postmenopausal women treated for breast cancer
A drug typically used to treat depression and anxiety can significantly reduce joint pain in postmenopausal women being treated for early stage breast cancer, according to new SWOG research to be presented Friday at a special plenary presentation at the San Antonio Breast Cancer Symposium.
December 9, 2016
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Dermatoscope could quickly diagnose causes of breastfeeding pain, BGU research shows
A dermatoscope, typically used to provide magnified images for identifying skin lesions, is also useful for quickly diagnosing the causes of breastfeeding pain, according to researchers at Ben-Gurion University of the Negev (BGU).
October 5, 2016
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Diabetes drug may be effective against deadly form of breast cancer, study suggests
Researchers have discovered that a metabolic enzyme called AKR1B1 drives an aggressive type of breast cancer. the study, 'AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program,' suggests that an inhibitor of this enzyme currently used to treat Diabetes patients could be an effective therapy for this frequently deadly form of cancer.
March 7, 2017
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Diabetes medication could be effective therapy for aggressive type of breast cancer
Around 15-20% of breast cancers are classified as "basal-like." this form of the disease, which generally falls into the triple-negative breast cancer subtype, is particularly aggressive, with early recurrence after treatment and a tendency to quickly spread, or metastasize, to the brain and lungs. There are currently no effective targeted therapies to this form of breast cancer, which is therefore often fatal.
March 7, 2017
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Direct communication could increase rate of women returning for breast cancer screening with MRI
A study published in the journal Health Communications shows that women at high risk for breast cancer who received a letter informing them of their options for additional imaging with contrast-enhanced MRI of the breast (in addition to a letter sent to their primary care physician) were more likely to return to the center for additional screening with MRI. the letter, which is included in the published paper, may help breast imaging centers navigate the complex legal, ethical and institutional landscapes in a way that increases the likelihood that women will follow through with American Cancer Society breast cancer screening recommendations for adjunct breast screening in women at elevated risk.
March 9, 2017
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Doctors Orders Differ from Mammogram Guidelines
Study finds that most still recommend the breast cancer screen for women in their early 40s
April 10, 2017
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Drug discovery approach predicts health impact of endocrine-disrupting chemicals
Breast cancer researchers from the Florida campus of the Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment–called environmental estrogens–can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer.
December 29, 2016
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Breast Cancer - E

Early Stage Breast Cancer and Double Mastectomy
Removing healthy breast is unlikely to extend survival, but some doctors don't mention this, researchers say
December 21, 2016
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Early-phase trial demonstrates shrinkage in pediatric neural tumors
In an early-phase clinical trial of a new oral drug, selumetinib, children with the common genetic disorder neurofibromatosis type 1 (NF1) and plexiform neurofibromas, tumors of the peripheral nerves, tolerated selumetinib and, in most cases, responded to it with tumor shrinkage. NF1 affects 1 in 3,000 people. the study results appeared Dec. 29, 2016, in the new England Journal of Medicine.
December 29, 2016
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Enzyme that regulates DNA repair may offer new precision treatments for breast and ovarian cancer
Researchers have identified an enzyme called UCHL3 that regulates the BRCA2 pathway, which is important for DNA repair, report scientists.
December 12, 2016
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Epigenetics provides new insights into the pathogenesis of lymphoma
Cancer cells have a different DNA methylation pattern from that of healthy cells. These patterns can be used to explain tumor-specific deviations in gene expression and to identify biomarkers for the detection of tumors, as well as associated prognosis and treatment planning.
October 5, 2016
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Even High-Fat Mediterranean Diet Good for You
Still protected against diabetes, heart disease and breast cancer
July 19, 2016
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Exercise improves memory in breast cancer survivors
Surprising finding: Self-reported memory problems in survivors linked to high stress regardless of treatment
July 8, 2016
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Exercise most important lifestyle change to help reduce risk of breast cancer recurrence
for patients with breast cancer, physical activity and avoiding weight gain are the most important lifestyle choices that can reduce the risk of cancer recurrence and death, according to an evidence-based review.
February 21, 2017
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Experimental drug may become key tool to target triple-negative breast cancer with immunotherapy
Previous studies at the University of Colorado Cancer Center show that the experimental drug AMPI-109 potently kills triple-negative breast cancer cells. But even the most compelling evidence of cell death in a dish isn't enough to push a drug into human clinical trials, even for triple-negative breast cancer, which has a high mortality rate and remains largely without targeted treatment options.
August 30, 2016
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Exposure to BPA Substitute, BPS, Multiplies Breast Cancer Cells
Bisphenol S (BPS), a substitute for the chemical bisphenol a (BPA) in the plastic industry, shows the potential for increasing the aggressiveness of breast cancer through its behavior as an endocrine-disrupting chemical, a new study finds.
April 3, 2017
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Breast Cancer - F

False positives from mammogram screening can be detrimental to future care
A study conducted by the University of Illinois, Chicago, and published this week by the American Association for Cancer Research, indicates that women who experience a false positive after mammogram screening are more likely to delay or avoid future screening appointments.
February 10, 2017
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Fat cells may play key role in battle against breast cancer
The research points to exercise -- which has none of the harmful side-effects of many cancer drugs -- as being a potentially beneficial therapy in some breast cancer patients
July 13, 2016
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Foods to eat and foods to avoid to fight breast cancer
While there is no one single food or diet that can prevent or cause breast cancer, diet is an area in which individual choices can make a real difference.
April 3, 2017
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Breast Cancer - G

Gamma Medica's LumaGEM Molecular Breast Imaging system to be installed at Henry Ford West Bloomfield Hospital
Gamma Medica, a leader in molecular breast imaging (MBI) technology, today announced that Henry Ford Health System has purchased Gamma Medica's LumaGEM Molecular Breast Imaging system. the system is set to be installed by the end of 2016 at Henry Ford West Bloomfield Hospital. the MBI technology will be offered as a secondary screening and diagnostic tool following X-ray mammography, particularly for women with dense breast tissue. this proven imaging modality will help improve cancer detection in women who are at greater risk of developing breast cancer.
November 4, 2016
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Genetic test may be able to predict need for chemotherapy in early-stage breast cancer
Patients with early stage breast cancer who have a low genetic risk of disease recurrence may not need to have chemotherapy, report researchers.
August 25, 2016
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Genetic variant of p53 gene linked to breast cancer risk in premenopausal African American women
African American women who carry the genetic variant could have an increased risk of breast cancer before menopause
February 27, 2017
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Good News for Older Women with Early Breast Cancer
A diagnosis of DCIS doesn't lower life expectancy in patients over 50, study finds
January 27, 2017
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Growing body of evidence supports use of mind-body therapies in breast cancer treatment
Meditation and yoga get highest grades for improving quality of life, study shows
April 24, 2017
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Breast Cancer - H

Hair dyes, relaxers tied to raised breast cancer risk
New research finds evidence of a link between use of certain hair products, such as dyes and relaxers, and raised risk of breast cancer in women. The findings also suggest that the effect is different between black and white women.
June 16, 2017
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Half of breast cancer patients experience severe side effects
Study finds side effects cause extra burden for patients, health care system
January 24, 2017
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HCI scientists uncover new way that bones get destroyed through breast cancer
Once breast cancer spreads through the body, it can degrade a patient's healthy bones, causing numerous problems. Scientists at Huntsman Cancer Institute (HCI) at the University of Utah have identified a new way that bones get destroyed through cancer. and they've also learned how to block that destruction with a new drug. Initial tests with patients show promising results.
January 25, 2017
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High breast density makes it hard to detect breast cancer on mammogram
Almost 8% of women have extremely high breast density, which can make it harder for health professionals to detect breast cancer on a screening mammogram. These women are also more likely to develop breast cancer in the future.
October 5, 2016
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High levels of calpain protein linked to improved survival of breast cancer patients
A family of proteins that help cancer cells survive and spread around the body may be associated with improved prognosis for some women receiving treatment for breast cancer, research has shown.
June 29, 2016
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High-Risk Women and Breast Cancer Gene Test
Only half got BRCA screen, and more than half of those who didn't said doctors never recommended it
February 7, 2017
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High-Tech Mammograms: More Cancer, False Positives
Digital technology leads to 'marked improvement' in detection rates, radiology expert says
February 28, 2017
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Hologic Genius 3D Tomosynthesis Mammography System FDA Approved for Better Visualization of Dense Breasts
Hologic received FDA approval to offer its Genius 3D Mammography system as superior to traditional 2D mammography for screening of women with dense breasts. Though Genius 3D has been available in the U.S. since 2011, recently performed clinical studies have demonstrated that "the exam improves invasive breast cancer detection while reducing unnecessary recalls among women of all breast densities, including those with dense breasts," according to Hologic.
June 9, 2017
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Hops extract activates chemical pathway in cells to help prevent breast cancer
An enriched hops extract activates a chemical pathway in cells that could help prevent breast cancer, according to new laboratory findings from the UIC/NIH Center for Botanical Dietary Supplements Research at the University of Illinois at Chicago.
July 12, 2016
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Hormonal contraceptives and hair dyes linked to increased risk of breast cancer
In her recent doctoral dissertation, researcher Sanna Heikkinen from the University of Helsinki and Finnish Cancer Registry evaluates the contribution of the use of hormonal contraceptives and hair dyes to the spectrum of breast cancer risk factors.
March 9, 2017
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Houston Methodist researcher receives $4 million to create triple negative breast cancer immunotherapy
Scientists at Houston Methodist received support from the U.S. Department of Defense (DoD) to reprogram cancer patients' immune cells to attack triple negative breast cancer, the most lethal form of breast cancer.
October 13, 2016
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How a small implanted device could help limit metastatic breast cancer
A small device implanted under the skin can improve breast cancer survival by catching cancer cells, slowing the development of metastatic tumors in other organs and allowing time to intervene with surgery or other therapies.
September 15, 2016
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Breast Cancer - I

I-SPY2 research initiative employs exciting new model for testing breast cancer drugs
In a new paradigm of breast cancer research, physicians are fast-tracking promising new experimental drugs for further study, while immediately dropping drugs and drug combinations that don't work.
July 8, 2016
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iBreastExam: Low Cost, Point-of-Care Breast Health Test
UE Lifesciences, a company with offices in the U.S. and India, has developed the iBreastExam, a low-cost point-of-care breast health test for use by community workers in low resource settings.
December 2, 2016
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Immune system plays dual role in breast cancer
The immune system plays a paradoxical role in the spread of breast cancer. some immune cells contribute to metastasis, while other cells can be activated to strengthen the effect of chemotherapy, outlines new research.
February 7, 2017
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Immunotherapy combination offers new hope for women with early stage triple negative breast cancer
A Yale Cancer Center clinical trial combining the immune checkpoint inhibitor (durvalumab/MEDI4736) with chemotherapy as preoperative treatment for early stage triple negative breast cancer disclosed a 71% pathologic complete response to the combination treatment in the initial phase I trial.
June 2, 2017
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Inflammatory breast cancer: Symptoms, diagnosis, and treatment
Inflammatory breast cancer is when cancer cells block the lymph vessels in the skin of the breast.
April 4, 2017
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Inhibition of RANK signaling pathway could be potential new therapy in breast cancer
Researchers at the Institute of Biomedical Research of Bellvitge, led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction in recurrences and metastases in breast cancer in a mouse animal model.
September 13, 2016
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Integration of multiple types of protein biomarkers improves ability to detect breast cancer
A first-time study published in PLOS ONE shows that a combined assessment of multiple types of protein biomarkers in the blood offers an important advancement for detecting early breast cancer. the study, conducted by Provista Diagnostics, compared the ability of Serum Protein Biomarkers (SPBs) and Tumor-Associated Autoantibodies (TAAbs), either alone or in combination, to detect breast cancer.
August 11, 2016
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Intense Chemo: Little Early Breast Cancer Benefit
U.S. cancer expert still sees role for the approach in certain patients
November 9, 2016
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Invasive lobular carcinoma: Symptoms, subtypes, diagnosis, and treatment
Invasive lobular carcinoma is a type of cancer that starts in the milk glands of the breast and spreads easily to surrounding tissue.
March 31, 2017
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IVF Won't Raise Risk for Breast Cancer
New findings should reassure the many women who undergo the fertility procedure, specialists said
July 19, 2016
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Breast Cancer - J

Just one alcoholic drink a day increases breast cancer risk, exercise lowers risk
Drinking just one glass of wine or other alcoholic drink a day increases breast cancer risk, finds a major new report.
May 23, 2017
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Just one small glass of wine per day increases breast cancer risk
Breast cancer is the most common form of cancer among women across the globe. New research suggests that as little as one alcoholic drink per day can increase breast cancer risk, while exercise and a healthful diet lowers the risk.
May 23, 2017
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Breast Cancer - K

Ki67 may help spare some breast cancer patients from sentinel lymph node biopsies
Breast cancer patients over 50 years old could be spared invasive procedures by use of stratification based on tumour size and molecular characteristics, including Ki67. the cell proliferation index Ki67 is significantly associated with lymph node metastases in patients aged over 50 years and with smaller tumours, which may help reduce the need for sentinel lymph node biopsies in some women, researchers report at the ESMO 2016 Congress in Copenhagen.
September 29, 2016
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Breast Cancer - L

Life-Changing Technology Shouldn't Have to Wait
Braster S.A. is a Poland-based company founded by scientists with a mission -- to save lives by giving women an easier, more effective and more comfortable way to conduct breast self-examinations at home. they believed that through regular home screening, more women would be able to detect breast cancer at an earlier stage, thereby living longer, healthier lives.
May 16, 2017
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Life-threatening childhood brain cancer: New insight
The most common type of malignant childhood brain cancer has been identified as seven separate conditions each needing a different treatment, new research has revealed.
May 23, 2017
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Living with breast cancer: Statistics on survival rates by stage
More than 80 percent of people diagnosed with breast cancer recover and go on to live for at least 10 years.
April 10, 2017
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Loneliness May Sabotage Breast Cancer Survival
Weak social ties linked to higher risk of recurrence, early death, researchers report
December 12, 2016
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Low-Dose Aspirin May Lower Breast Cancer Risk
But experts say it's too soon to recommend it for this purpose
May 1, 2017
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Breast Cancer - M

Mammogram Guidelines Have Changed, But Are Doctors Listening?
Study finds that most still recommend the breast cancer screen for women in their early 40s
April 10, 2017
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Mammography trends show improved cancer detection, more biopsies
The shift from film to digital technology appears to have improved cancer detection rates for diagnostic mammography, but also has increased the abnormal interpretation rate, which may lead to more women undergoing biopsies for benign conditions, according to a new study.
February 28, 2017
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Mammography versus thermography: Comparing the benefits
Breast cancer screening is used to identify breast cancer in women who have no physical symptoms. It is hoped that finding breast cancer early will enable women to undergo less invasive treatments, with better outcomes.
March 29, 2017
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Many Women Skip Mammograms After False Positive
But imaging experts stress that doing so may raise risk for actual breast cancer
February 9, 2017
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Massive drop in mortality from breast cancer
The rate of mortality from breast cancer has fallen by one third over the last 30 years. this is due to improvements in early detection, the refinement of treatment concepts and the development of new ones. Today, an important issue for breast cancer experts is also how they can improve the quality of life of their patients.
March 9, 2017
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Mayo researchers discover important differences in breast tissue microbiome of women with cancer
A team of Mayo Clinic researchers has identified evidence of bacteria in sterilely-obtained breast tissue and found differences between women with and without breast cancer. the findings are published in the Aug. 3 issue of Scientific Reports.
August 03, 2016
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Metastasized breast cancer: Surgery prior to drug treatment not beneficial
Women suffering from metastasized breast cancer do not benefit from surgery performed prior to drug treatment, new research indicates. This could cause a paradigm shift in treatment of the disease.
June 8, 2017
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Metastatic breast cancers: Characterizing the profile of metastases for improved treatment
A new study offers a better understanding of the progression of breast cancer. the conclusions could have an impact on care for patients suffering from a metastatic breast cancer. this is one of the first studies based on the analysis of multiple metastases obtained at the time of patient autopsies.
April 24, 2017
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Mitochondrial stress can trigger tumor-related metabolic shifts, study finds
Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.
July 7, 2016
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More Asian-American Women Getting Breast Cancer
Out of 7 nationality groups studied, only Japanese women didn't have an overall increase in the disease
April 14, 2017
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More Breast Cancer Patients Should Consider Radiation
Mastectomy patients with small tumors, fewer lymph nodes involved, benefit from the therapy, cancer experts agree
September 21, 2016
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More patients with early-stage breast cancer may be able to avoid chemotherapy in the future
For women with intermediate risk recurrence score from 21-gene expression assay, less may be more
February 16, 2017
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More women opting to remove a healthy breast after cancer diagnosis
An increasing number of women diagnosed with cancer in one breast choose to have the other breast surgically removed as well, according to a new study co-led by the American Cancer Society.
March 29, 2017
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Most women unaware of breast density's effect on cancer risk, study finds
Most women don't know that having dense breasts increases their risk for breast cancer and reduces a mammogram's ability to detect cancer, according to a study. a random phone survey of 1,024 Virginia women ages 35 to 70 found that just 1 in 8 women were aware that breast density is a risk factor for breast cancer, while just 1 in 5 women knew that dense breasts reduced the sensitivity of mammograms to find tumors.
November 21, 2016
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MSK scientists discover epigenetic mechanism promoting breast cancer
Bottom Line: Researchers from Memorial Sloan Kettering Cancer Center (MSK) have identified, for the first time, an epigenetic mechanism promoting breast cancer. the team found that inhibition of the PI3K pathway leads to activation of ER-dependent transcription through the epigenetic regulator KMT2D.
March 24, 2017
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Multifunctional RNA Nanoparticles Could Overcome Treatment Resistance in Breast Cancer
Researchers at the University of Cincinnati (UC) College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients.
December 14, 2016
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Breast Cancer - N

Nanoparticle paves the way for new triple negative breast cancer drug
A potential new drug to tackle the highly aggressive 'triple negative' breast cancer - and a nanoparticle to deliver it directly into the cancer cells - have been developed by UK researchers.
March 16, 2017
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Nanoparticles could be used to overcome treatment-resistant breast cancer
Researchers at the University of Cincinnati (UC) College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients.
December 14, 2016
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Natural compound could improve treatment of triple-negative breast cancer
More than 100 women die from breast cancer every day in the United States. Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites.
January 24, 2017
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Natural compound could reduce risk of developing triple-negative breast cancer metastasis
More than 100 women die from breast cancer every day in the United States. Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites.
January 24, 2017
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Never Too Old for a Mammogram?
Researchers find benefits for some women up to the age of 90
November 28, 2016
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New 3D mammary gland model may pave way for better understanding of breast cancer
A team of researchers from Cardiff University and Monash Biomedicine Discovery Institute has succeeded in creating a three-dimensional mammary gland model that will pave the way for a better understanding of the mechanisms of breast cancer.
October 27, 2016
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New Cancer Therapy Shows Promise in Treating Aggressive Brain Tumors
By boosting the power of a patient's immune cells, researchers from the City of Hope Beckman Research Institute have demonstrated the potential for a revolutionary new therapy to treat a particularly aggressive form of brain cancer. But given the limited results, many questions remain.
December 29, 2016
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New computer program can predict underlying genomics of ER+ breast cancer
The number of tubules in tumors may predict which women with estrogen receptor positive (ER+) breast cancer will benefit from hormone therapy alone and which require chemotherapy, researchers at Case Western Reserve University have found.
September 7, 2016
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New data reveals significant correlation between OA breast imaging results and histologic data of breast masses
Seno Medical Instruments, Inc., the company pioneering the development of opto-acoustic (OA) technology as a new tool to improve the process of diagnosing breast cancer, today announced results from two analyses of the company's European MAESTRO post-market surveillance study.
December 14, 2016
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New Drug May Slow Advanced Breast Cancer
A recently approved drug can help slow the progression of advanced breast cancer, a new clinical trial confirms.
November 16, 2016
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New findings support use of integrative therapies for treating breast cancer patients
In newly updated clinical guidelines from the Society for Integrative Oncology (SIO), researchers at Columbia University's Mailman School of Public Health and the Herbert Irving Comprehensive Cancer Center with an interdisciplinary team of colleagues at MD Anderson Cancer Center, University of Michigan, Memorial Sloan Kettering Cancer Center, and other institutions in the U.S. and Canada, analyzed which integrative treatments are most effective and safe for patients with breast cancer.
April 24, 2017
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New gene discovered that is driving drug resistance
A gene that is 'revving the engine of cancer' against the world's most common breast cancer drug has been discovered by scientists.
April 4, 2017
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New gene identified as cause, early indicator of breast cancer
When mutated, a gene known for its ability to repair DNA, appears to instead cause breast cancer, scientists report. Mutations of the gene are known to be present in both early onset breast and ovarian cancer. now scientists have shown that the stem, or progenitor cells, which should ultimately make healthy breast tissue, can also have GT198 mutations that prompt them to instead make a perfect bed for breast cancer.
March 18, 2016
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New insights into mechanisms of breast cancer development and resistance to therapy
Why does breast cancer develop and how come certain patients are resistant to established therapies? Researchers have gained new insights into the molecular processes in breast tissue. they identified the tumor suppressor LATS as a key player in the development and treatment of breast cancer.
January 9, 2017
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New mathematical model can help predict breast cancer growth, occurrence of metastases
Personalized medicine is a healthcare approach in which medical procedures are tailored to the individual patient's genetic, physiological, and biochemical type along with other characteristics. Cancer treatment is one type of care where a personalized approach is most needed and often applied.
July 18, 2016
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New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene
A new measurement standard developed by the National Institute of Standards of Technology (NIST) has been used successfully by the Frederick National Laboratory for Cancer Research to check the performance of next-generation DNA-sequencing technologies for evaluating gene variations associated with an increased risk of breast cancer.
August 18, 2016
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New research highlights how fat cells could help find most effective way to combat breast cancer
New research led by York University Professor Michael Connor highlights how fat cells could help determine the most effective way to fight breast cancer; including using exercise to combat the disease.
July 13, 2016
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New subcutaneous treatment reduces pain, increases survival chances of breast cancer patients
Breast cancer treatments are usually painful, time consuming and aggressive, which leads to long term hospitalization, medical staff and high economic expenses.
July 19, 2016
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New study to investigate how genetic factors contribute to breast cancer disparities
The largest study ever to investigate how genetic and biological factors contribute to breast cancer risk among black women launched today. this collaborative research project will identify genetic factors that may underlie breast cancer disparities. the effort is funded by the National Cancer Institute (NCI), part of the National Institutes of Health.
July 7, 2016
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New technique can test effectiveness of treatments for breast cancer metastases in bone
A new laboratory technique developed by researchers at Baylor College of Medicine and other institutions can rapidly test the effectiveness of treatments for life-threatening breast cancer metastases in bone.
April 21, 2017
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New X-ray technique could improve bomb detection and breast cancer treatment
An exciting X-ray imaging technology has been successfully developed to the point where it is now ready for translation into all kinds of beneficial applications, including potentially life-saving uses in security and healthcare.
December 13, 2016
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NIH launches largest-ever study of breast cancer genetics in black women
Findings could inform breast cancer disparities.
July 6, 2016
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NorthShore launches first clinical trial to examine GRS test for cancer risk assessment
Researchers at NorthShore University HealthSystem (NorthShore) have launched the first clinical trial to investigate a genetic risk score (GRS) test to predict the risk of breast, prostate and colorectal cancer in the primary care setting.
July 19, 2016
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Novartis to collaborate with IBM Watson Health for improving outcomes in advanced breast cancer
Novartis today announced a first-of-its-kind collaboration with IBM Watson Health on an initiative to optimize cancer care and improve patient outcomes. The two companies will collaborate to explore development of a cognitive solution that uses real-world data and advanced analytical techniques with the aim to provide better insights on the expected outcomes of breast cancer treatment options.
June 5, 2017
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Novel approach can reveal personalized breast cancer treatments
Researchers have developed a new way to approach breast cancer treatment. First, they search for the proteins that drive tumor growth, and then test in the lab drugs that potentially neutralize these specific biological drivers.
March 28, 2017
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Novel compound that engages 'second arm' of immune system reduces breast tumors, metastases
A compound able to reverse the allegiance of innate immune system cells - turning them from tumor enablers into tumor opponents - caused breast tumors in mice to shrink and withdraw from distant metastases, scientists report.
March 8, 2017
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Breast Cancer - O

'Omics' data improves breast cancer survival prediction
Whole-genome gene expression and methylation data offer more predictive power than commonly-used clinical information, including cancer stage or subtype
July 6, 2016
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One of the most common viruses in humans may promote breast cancer development
Findings could lead to new prevention strategies
August 1, 2016
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Breast Cancer - P

Parenchymal enhancement in breast tissue is not an indicator for increased cancer risk
Women with a certain gene mutation are among the high-risk patients for breast cancer. with a magnetic resonance tomography (MRT) it is possible to detect tissue with measurable active blood supply which indicates an increased breast cancer risk. now experts are now exploring whether tissue with active blood supply visible with MRT could indicate a grater risk in those patients without gene mutation. the result: so-called "background parenchymal enhancement" of the breast in these women is not associated with breast cancer.
July 25, 2016
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PHD2-knockdown overcomes breast cancer cell death in response to glucose starvation
B55α is one of the regulatory subunits of the PP2A phosphatase. this phosphatases has been associated to the control of many biological functions but the multiplicity of complexes that can be formed by the combination of different subunits renders this protein hard in its understanding. the Massimiliano Mazzone group (VIB-KU Leuven) has recently demonstrated that PP2A/B55α promotes the growth of colorectal cancer, by dephosphorylating PHD2 and modifying its enzymatic properties. PHD2 is a member of a family of enzymes crucial for the cellular response to hypoxia.
March 22, 2017
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Pioneering Nanobiodevice Could Quickly Isolate Cancer Biomarkers with High Resolution
Like DNA, ribonucleic acid (RNA) is a type of polymeric biomolecule essential for life, playing important roles in gene processing. Short lengths of RNA called microRNA are more stable than longer RNA chains, and are found in common bodily fluids.
March 9, 2017
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Place matters in late diagnosis of colorectal cancer, study finds
In addition to a person's race or ethnicity, where they live can matter in terms of whether they are diagnosed at a late stage for colorectal cancer, according to a recent study.
January 9, 2017
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Poor diet during teens, early adulthood may raise breast cancer risk
The risk of developing premenopausal breast cancer may be higher for women who have a poor diet during adolescence and early adulthood, new research finds.
March 1, 2017
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Potential drug candidates halt prostate and breast cancer growth
Two new drug candidates have now been designed to target prostate and triple negative breast cancers. the new research demonstrates that a new class of drugs called small molecule RNA inhibitors can successfully target and kill specific types of cancer.
March 9, 2017
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Practical Advice for Living with Breast Cancer
Life after a breast cancer diagnosis doesn't have to be a mystery. Lots of women have been in your shoes. some of them have shared with us how to deal with the day-to-day challenges you may face on your road to recovery.
August 08, 2016
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Precision medicine test helps guide breast cancer patients' chemotherapy decision
One of the earliest widespread applications of precision medicine in cancer care is helping patients and physicians decide whether chemotherapy is needed, a new study finds.
October 22, 2016
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Protective effect of ER-beta more pronounced in breast cancer patients who undergo chemotherapy
It is known from previous research that the ER-beta estrogen receptor often has a protective effect. a new study from Lund University in Sweden has found that this effect is more pronounced in patients that undergo chemotherapy.
December 14, 2016
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Protein associated with improved survival in some breast cancer patients
A family of proteins that help cancer cells survive and spread around the body may be associated with improved prognosis for some women receiving treatment for breast cancer, research has shown.
June 29, 2016
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Proteins which suppress the growth of breast cancer tumors discovered
A type of protein has been discovered that could hold the secret to suppressing the growth of breast cancer tumors, say scientists.
June 12, 2017
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Breast Cancer - R

Rate of mastectomies decreases with adoption of breast tumor margin guidelines, study finds
What this means in the overtreatment debate for breast cancer
June 5, 2017
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Regular use of aspirin can lower risk of breast cancer for women
A new study identifies low-dose aspirin as a potential cancer prevention tool
May 1, 2017
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Relaxing acupressure improves fatigue levels in breast cancer survivors
Acupressure helped reduce persistent fatigue in women who had been treated for breast cancer, a new study finds.
July 7, 2016
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Research consortium to receive 5.1 million euros to develop new device for breast cancer diagnosis
A large European research consortium headed by the University of Twente (UT) is to receive grants of more than five million euros, predominantly from the EU, to develop a new imaging device for the diagnosis of breast cancer. a prototype of the device will be ready for large scale testing and production in four years.
September 15, 2016
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Research findings could lead to development of improved breast cancer drugs
Biomedical scientists have revealed the inner workings of a group of proteins that help to switch critical genes on and off during blood-cell production, in a finding that could lead to the development of new and improved cancer drugs.
August 09, 2016
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Research shows how adipose tissue reduces efficiency of radiotherapy in breast cancer patients
According to research published online in The FASEB Journal, repeated irradiation of breast fat (also known as adipose tissue) produces an inflammatory response that ultimately reduces the efficiency of radiotherapy in breast cancer patients. This research was based on a recent discovery that there is an inflammatory interaction between breast tumors and adipose tissue.
June 8, 2017
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Researchers aim to stop breast cancer metastasis from happening altogether
A new Tel Aviv University study finds that combining genetic therapy with chemotherapy delivered to a primary tumor site is extremely effective in preventing breast cancer metastasis.
October 5, 2016
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Researchers develop two-pronged approach to personalize breast cancer treatment
The goal of cancer therapy is to destroy the tumor or stop it from growing and spreading to other parts of the body. Reaching toward this goal, a team of researchers from various institutions, including Baylor College of Medicine, Washington University School of Medicine in St. Louis and the Broad Institute of MIT and Harvard, has developed a new way to approach breast cancer treatment.
March 28, 2017
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Researchers developing quick, inexpensive test to assess ER+ breast cancers
Researchers are teaming with industry to develop a quick and inexpensive test to predict which women with ER+ breast cancer need chemotherapy and which need only the more tolerable hormonal therapy.
July 11, 2016
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Researchers discover key to drug resistance in common breast cancer treatment
Three-quarters of all breast cancer tumors are driven by the hormone estrogen. These tumors are frequently treated with drugs to suppress estrogen receptor activity, but unfortunately, at least half of patients do not respond to these treatments, leaving them with drug-resistant tumors and few options. Now, scientists have found that two immune system molecules may be key to the development of drug resistance in estrogen-driven breast cancers.
March 19, 2017
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Researchers discover mutation hotspots that act like backseat drivers for breast cancer development
Researchers at the Wellcome Trust Sanger Institute have discovered 'hotspots' of mutations in breast cancer genomes, where mutations thought to be inactive 'passengers' in the genome have now been shown to possibly drive further cancerous changes. Reported in Nature Genetics today, the study found 33 mutation hotspots, which act like backseat drivers for cancer development.
January 23, 2017
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Researchers discover novel mechanism to stop the spread of breast cancer
Controlling the levels of the TIP60 protein, which is a tumor suppressor, could potentially prevent the spread of breast cancer cells, a team of has found.
November 23, 2016
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Researchers examine link between income level and cancer diagnosis
Do wealthier people receive too much medical care? In a Perspective article recently published in the New England Journal of Medicine, H. Gilbert Welch, MD, and Elliott Fisher, MD, of The Dartmouth Institute for Health Policy and Clinical Practice examine the association between income level and cancer diagnosis.
June 8, 2017
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Researchers explore impact of hair products on breast cancer risk
Can use of hair products have an impact on breast cancer risk for women? That is a question explored by Rutgers University investigators -- and colleagues from Roswell Park Cancer Institute, Massachusetts General Hospital and Moffitt Cancer Center. Lead author of the work Adana A.M. Llanos, PhD, MPH of Rutgers Cancer Institute of New Jersey and Rutgers School of Public Health along with author Elisa V. Bandera, MD, PhD of Rutgers Cancer Institute, Rutgers Robert Wood Johnson Medical School and Rutgers School of Public Health share more about the work which examined use of hair dyes, hair relaxers and cholesterol-based hair products in African-American and Caucasian women.
June 14, 2017
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Researchers find key genetic driver for rare type of triple-negative breast cancer
New mouse model leads to surprising discovery that sheds light on metaplastic breast cancer
January 6, 2017
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Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy
Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects.
October 5, 2016
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Researchers identify new way to prevent chemotherapy resistance in lung and breast cancers
Researchers at the University of Bradford have discovered a way to prevent chemotherapy resistance in lung cancer by blocking a protein found in cancer cells.
October 4, 2016
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Researchers quantify immune cells associated with future breast cancer risk
Researchers have quantified the numbers of various types of immune cells associated with the risk of developing breast cancer, outlines a new report.
February 8, 2017
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Researchers provide "benchmark" amid changing breast cancer screening guidelines
Different professional organizations and societies continue to disagree over the best time to start and discontinue breast cancer screening, as well as what the optimal interval time should be between mammograms.
April 12, 2017
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Researchers receive $2 million PCORI funding to analyze use of decision aids in breast cancer treatment
A research team at the Dartmouth Institute for Health Policy and Clinical Practice has received a $2 million funding award from the Patient-Centered Outcomes Research Institute (PCORI) to conduct a research project that is likely to change the way women and their doctors make decisions about breast cancer surgery.
August 02, 2016
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Researchers stumble onto a new role for breast cancer drug
Tamoxifen stops immune cells from destroying injured eye cells in mice
May 31, 2017
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Researchers uncover mechanism of resistance used by triple negative breast cancer
Breast cancer cells are evasive, finding ways to bypass drugs designed to stop their unchecked growth. In a new study, researchers uncovered a mechanism of resistance used by a particularly aggressive breast cancer type, and revealed a possible drug combination that could stop cancer growth and also help to prevent resistance.
January 20, 2017
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'Rewired' cells show promise for targeted cancer therapy
Human immune cells rationally engineered to sense, respond to tumor signal
December 12, 2016
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Rogue breast tumor proteins point to potential drug therapies
Such treatment options are missed by genomic sequencing
March 28, 2017
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Rogue proteins involved in breast cancer point to potential treatment options
For patients with difficult-to-treat cancers, doctors increasingly rely on genomic testing of tumors to identify errors in the DNA that indicate a tumor can be targeted by existing therapies. But this approach overlooks another potential marker -- rogue proteins -- that may be driving cancer cells and also could be targeted with existing treatments.
March 28, 2017
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Role of common risk factors in ER-positive, ER-negative breast cancer
Researchers have examined the role of common risk factors in the development of ER-positive and ER-negative breast cancers. the study sheds new light on how a woman's age, weight, and menopausal status affect her risk for breast cancer.
January 9, 2017
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Breast Cancer - S

Salmonella protein can reduce drug resistant molecule found in cancer cells
A surprising result in an experiment on Salmonella bacteria has led to a discovery that may make drug resistant cancer cells more treatable by conventional chemotherapies. Scientists at the University of Massachusetts Medical School have found that the Salmonella protein SipA naturally reduces a well-known drug resistant molecule found in many different types of cancer cells.
July 25, 2016
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SAVI SCOUT Radiation-Free Breast Cancer Localizing Seeds Cleared for Up to 30-day Implants
Cianna Medical, a firm based in Aliso Viejo, California, won FDA clearance for its SAVI SCOUT system to be used to tag breast cancer lumps up to thirty days prior to surgical removal. Typically, lumps are first identified and localized, with either a radioactive seed or a guidewire left behind to help get back to the exact spot during the lumpectomy.
August 18, 2016
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Scalp cooling can lessen chemotherapy-induced hair loss in some breast cancer patients
Scalp cooling can lessen some chemotherapy-induced hair loss - one of the most devastating hallmarks of cancer - in certain breast cancer patients, according to a new multicenter study from UC San Francisco, Weill Cornell Medicine and three other medical centers.
February 15, 2017
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Screening for prolactin receptor could help improve TNBC prognosis and treatment
A study conducted at the Research Institute of the McGill University Health Centre (RI-MUHC) suggests screening breast cancer patients for the prolactin receptor could improve the prognosis for patient and may help them avoid unnecessary and invasive treatments.
October 22, 2016
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Scientists create innovative drug design strategy to improve breast cancer treatment
A new study offers a novel structure-based drug design strategy aimed at altering the basic landscape of this type of breast cancer treatment.
November 21, 2016
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Scientists discover the 'switch' that makes breast cancer cells aggressive
By controlling a molecular switch, scientists could potentially make aggressive cancers more sensitive to conventional drugs and improve treatment outcomes, say researchers.
November 1, 2016
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Scientists find link between p53 gene in African American women and breast cancer risk
Scientists at the Wistar Institute in collaboration with Roswell Park Cancer Institute found a significant association between a rare genetic variant of the p53 gene present in African American women and their risk of developing breast cancer in premenopausal age.
February 27, 2017
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Scientists identify bone degradation process within metastatic breast cancer
Phase 1 clinical trial shows promising results with new drug
January 25, 2017
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Scientists identify chain reaction that shields breast cancer stem cells from chemotherapy
Working with human breast cancer cells and mice, researchers say they have identified a biochemical pathway that triggers the regrowth of breast cancer stem cells after chemotherapy.
February 22, 2017
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Scientists identify protein involved in restoring effectiveness of common treatment for breast cancer
Breast cancer is the most frequently diagnosed cancer among women, with estrogen-receptor-positive (ER+) being the most common type. Drugs used to treat this cancer, such as tamoxifen and Faslodex, block the hormone estrogen receptor that ER+ cancer cells need to grow. One problem with these treatments is that many tumors initially responsive to the drugs develop resistance, making the medicines less effective.
October 3, 2016
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Severe Side Effects from Breast Cancer Therapy
Digestive troubles, pain, skin irritation and arm swelling among possible problems
January 24, 2017
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Small implanted device can improve breast cancer survival by detecting cancer cells
Device facilitates early detection of metastatic cancer cells and improves survival, study finds
September 15, 2016
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Social media linked to more satisfaction with breast cancer treatment decisions
But study cautions that many breast cancer patients are not using it
July 28, 2016
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Some Breast Cancer Drugs and Blood Vessel Damage
But findings from small study are unlikely to change current practice, doctors say
December 9, 2016
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Soy May be Protective for Breast Cancer Survivors
Study of 6,200 women finds the food linked to lower risk of death after nearly a decade of follow-up
March 7, 2017
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Stereotactic partial breast radiation decreases treatment time from six weeks to just days
UT Southwestern Medical Center researchers found in a recent phase one clinical trial that stereotactic partial breast radiation was as safe as traditional radiation but decreased treatment time from six weeks to just days.
May 9, 2017
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Stiff, oxygen-deprived tumors promote spread of cancer
Specific conditions -- tumor hardness and a lack of oxygen at the tumor's core -- lead to breast-cancer progression in laboratory cultures, researchers have found.
September 13, 2016
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Study demonstrates safety and effectiveness of new SLN radiotracer in breast cancer patients
Determining whether breast cancer has spread to sentinel lymph nodes (SLN) is key to prognosis and treatment, making SLN mapping critical. the blue dyes commonly used to identify SLNs spread quickly to other nodes and is poorly retained by the SLNs (less than five minutes). this requires the surgeon to identify SLNs quickly. Allergic reaction to the dyes has also been a concern.
August 16, 2016
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Study estimates number of U.S. women living with metastatic breast cancer
A new study shows that the number of women in the United States living with distant metastatic breast cancer (MBC), the most severe form of the disease, is growing. This is likely due to the aging of the U.S. population and improvements in treatment. Researchers came to this finding by estimating the number of U.S. women living with MBC, or breast cancer that has spread to distant sites in the body, including women who were initially diagnosed with metastatic disease, and those who developed MBC after an initial diagnosis at an earlier stage.
May 18, 2017
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Study estimates number of U.S. women living with metastatic breast cancer
The number of women in the United States living with distant metastatic breast cancer, the most severe form of the disease, is growing, new research shows.
May 18, 2017
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Study finds 'striking' use of double mastectomy
Nearly half of early stage breast cancer patients considered having double mastectomy and one in six received it -- including many who were at low risk of developing a second breast cancer, a new study finds.
December 21, 2016
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Study identifies new gene that suppresses breast cancer in mice
In recent years, the incidence of breast cancer has been increasing worldwide, and breast cancer is becoming a serious object of public concern. the onset of breast cancer is closely related to the sex hormone estrogen, and estrogen antagonists such as tamoxifen have been used as anti-breast cancer drugs.
September 13, 2016
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Study identifies protein in tumor microenvironment that promotes breast cancer spread
To understand what makes breast cancer spread, researchers are looking at where it lives - not just its original home in the breast but its new home where it settles in other organs. What's happening in that metastatic niche where migrated cancer cells are growing?
February 16, 2017
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Study identifies recurrent genomic alterations in subset of breast cancer
A genomic analysis study by Rutgers Cancer Institute of new Jersey investigators and other colleagues has identified recurrent genomic alterations in a subset of breast cancer that are typically associated with a form of thyroid cancer and an intestinal birth defect known as Hirschsprung disease.
December 9, 2016
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Study on mice demonstrates the action of strawberries against breast cancer
Strawberry extract can inhibit the spread of laboratory-grown breast cancer cells, even when they are inoculated in female mice to induce tumors, new research shows. However, the scientists do point out that these results from animal testing can not be extrapolated to humans.
April 19, 2017
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Study reports sampling method used for new breast cancer tests may need to be refined
Not only is breast cancer more than one disease, but a single breast cancer tumor can vary within itself, a finding that University of Pittsburgh Cancer Institute (UPCI) researchers discovered has the potential to lead to very different patient treatment plans depending on the tumor sample and diagnostic testing used.
July 28, 2016
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Study reveals unexpected process for acquiring chemoresistance in breast cancers
A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. the findings, reported by Andre Nussenzweig, Ph.D., and Shyam Sharan, Ph.D., at the National Cancer Institute (NCI), part of the National Institutes of Health, and colleagues, appeared July 21, 2016, in Nature.
July 25, 2016
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Study shows one in five older women with breast cancer experience functional decline
In a study of older women with newly diagnosed stage I to III breast cancer, approximately one in five lost the ability to complete some of the basic tasks necessary for independent living within one year of initiating treatment. the study also found that a simple survey can help identify which women are at risk of such functional decline.
June 28, 2016
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Study: Half of women treated for early stage breast cancer report severe side effects
Nearly half of women treated for early stage breast cancer reported at least one side effect from their treatment that was severe or very severe, a new study finds.
January 24, 2017
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Symptoms from other causes may be mistaken for side effects of breast cancer drug
Women taking tamoxifen to prevent breast cancer were less likely to continue taking the drug if they suffered nausea and vomiting, according to new data presented at the San Antonio Breast Cancer Symposium today.
December 9, 2016
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Synthetic nanochannels for iodide transport
Exchange of iodide (iodine ions) between bloodstream and cells is crucial for the health of several organs and its malfunctioning is linked to goiter, hypo- and hyperthyroidism, breast cancer, and gastric cancer. Researchers have devised nanostructures that function as channels for iodide transport in cell membranes. This study may lead to diagnosis and treatment of iodide transport disorders.
June 8, 2017
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Synthetic nanochannels for iodide transport
Exchange of iodide (iodine ions) between bloodstream and cells is crucial for the health of several organs and its malfunctioning is linked to goiter, hypo- and hyperthyroidism, breast cancer, and gastric cancer.
June 8, 2017
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Breast Cancer - T

Tamoxifen May Get Blamed for Unrelated Symptoms
Perceived side effects might lead some to stop taking the breast cancer preventative, study finds
December 9, 2016
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Targeting breast cancer metabolism to fight the disease
How does a cancer cell burn calories? new research shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells.
November 28, 2016
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Technique to minimally disrupt lower suspensory ligaments improves breast reduction outcomes
Research led by Frank Lau, MD, Assistant Professor of Clinical Surgery at LSU Health new Orleans School of Medicine, has found that long-term breast reduction outcomes can be improved by using techniques that minimally disrupt the lower breast suspensory ligaments. the paper, the Sternum-Nipple Distance is Double the Nipple-Inframammary Fold Distance in Macromastia, is published Ahead-of-Print online in the Annals of Plastic Surgery.
April 14, 2017
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Teen invents bra that could detect breast cancer early
Mexican student wins a global entrepreneur award for designing a bra that aids with early breast cancer detection.
May 8, 2017
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Telerehabilitation through Internet proved to ameliorate both the health and the quality of life of women suffering breast cancer
Telerehabilitation (rehabilitation with the help of the Internet, using the application Skype as a control platform) may help to alleviate the side effects associated with breast cancer and its treatment, like pain, fatigue, strength loss, deterioration of the quality of life, etc., new research suggests.
October 26, 2016
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The complex crosstalk between obesity, breast cancer
A new study describes how inflammation that characterizes fatty tissue is one of the main microenvironment actors responsible for promoting cancer. the authors also describe the involvement of steroid hormones and others factors produced by adipose tissue in breast cancer development.
July 13, 2016
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The way breast cancer genes act could predict your treatment
Effective treatment options for breast cancer can be predicted based on the way certain breast cancer genes act or express themselves, a researcher has concluded.
February 21, 2017
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Three-week radiation therapy treatment given post mastectomy is safe and effective
A shorter course of radiation therapy given to breast cancer patients following mastectomy is safe and effective and cuts treatment time in half. that is according to data from a phase II clinical trial by investigators who examined a hypofractionated regimen given over three weeks versus the traditional six week course of treatment.
May 2, 2017
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Treatment using PARP inhibitor shrinks tumors in breast cancer patients with BRCA mutations
All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at the University of Texas MD Anderson Cancer Center.
October 5, 2016
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Trials Produce Promising Breast Cancer Drugs
Adaptive study design allows researchers to match medications to patients more quickly
July 7, 2016
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Triple-negative breast cancer: Nanodelivery of new drug shows promise
Using nanoparticles to deliver an experimental drug directly into triple-negative breast cancer cells could be an effective way to fight this very aggressive cancer, which has very few treatment options. the drug is a peptide that is unstable, and delivering it directly into cells means that it can reach its target before degrading.
March 17, 2017
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TSRI researchers develop new drug candidates to target prostate and triple negative breast cancers
Scientists on the Florida campus of the Scripps Research Institute (TSRI) have designed two new drug candidates to target prostate and triple negative breast cancers.
March 9, 2017
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Tucatinib (ONT-380) progressing in pivotal trial against HER2+ breast cancer
Twenty-seven percent of 50 heavily pretreated patients with stage IV HER2+ breast cancer saw clinical benefit from the drug Tucatinib (ONT-380) , with at least 'stable disease' at 24 or more weeks after the start of treatment.
January 11, 2017
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Two drug combinations may reduce mortality rates in breast cancer patients, study reveals
Patient health records revealed two drug combinations that may reduce mortality rates in breast cancer patients, according to a study led by researchers at the Stanford University School of Medicine.
December 9, 2016
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Two Genes May Help Predict Breast Cancer Survival
Research suggests that tracking DNA activity patterns may someday help women with certain tumor types
August 18, 2016
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Breast Cancer - U

UCSF researchers receive funding from Susan G. Komen to support breast cancer research
Three UCSF researchers have been awarded $680,000 in grants from Susan G. Komen to support projects in breast cancer research. the grants to UCSF were among a total of $32.7 million given to researchers in 23 states and seven countries for projects including research into metastatic disease, novel treatments for aggressive types of breast cancer, new technologies, and health equity.
September 20, 2016
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Uncovering a new principle in chemotherapy resistance in breast cancer
A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.
July 20, 2016
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Uncovering a new principle in chemotherapy resistance in breast cancer
A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.
July 20, 2016
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Understanding and treating ER-positive breast cancer
Certain breast cancers occur as a direct result of the many hormone receptors on the surface of breast cells. These receptors are made up of proteins that accept hormones that tell the cell when to grow. In cases of cancerous cells, the cell begins to grow uncontrollably.
April 7, 2017
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Understanding when eating soy might help or harm in breast cancer treatment
Researchers have used animal models to reveal new information about the impact -- positive and negative -- that soy consumption could have on a common breast cancer treatment.
February 1, 2017
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Updated testing guidelines make more women eligible for herceptin, yet benefit uncertain
Changes to HER2 testing guidelines for breast cancer in 2013 significantly increased the number of patients who test HER2-positive, according to a new study. Cancers that have an excess of HER2 protein or extra copies of the HER2 gene are called HER2-positive and can be treated with drugs like Herceptin that target HER2. HER2 stands for human epidermal growth factor receptor 2.
July 27, 2016
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Breast Cancer - V

Vaccine shows promising results for early-stage breast cancer patients
HER2-targeted dendritic cell vaccines stimulate immune responses and regression of HER2-expressing early-stage breast tumors
January 3, 2017
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Videssa Breast Blood Diagnostic Test for Breast Cancer
Provista Diagnostics, a company based in New York City, has developed the Videssa Breast blood-based proteomic test to detect breast cancer. At present, after an abnormal mammogram doctors are faced with a difficult decision: whether to carry out an invasive biopsy or not. "When a mammogram yields an abnormal result, the challenge for every clinician is to decide which patients need follow-up, further imaging or biopsy,' said Josie R. Alpers, MD, a radiologist at Avera McKennan Hospital & University Health Center.
May 30, 2017
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Vitamin D May Affect Breast Cancer Survival
Study link is strongest in women who have not entered menopause, researchers report
November 10, 2016
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Breast Cancer - W

Western Diet Tied to Denser Breast Tissue
Previous research has linked higher density to increased risk of breast cancer
August 08, 2016
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What to Know Before you Change your Breast Size
You'd like to go up or down a cup size -- or more. you want implants for more curves, or to take some of the pressure off your back with breast reduction surgery.
August 08, 2016
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Whole-genome omics data can improve accuracy of breast cancer survival predictions
Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed. new research reveals that profiling primary tumor samples using genomic technologies can improve the accuracy of breast cancer survival predictions compared to clinical information alone.
July 6, 2016
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Why Breast Cancer Survivors Should Exercise
Moderate physical activity can ease stress that impairs memory, study suggests
July 8, 2016
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With breast cancer, the best treatment may be no treatment
Mammography, the boob-smooshing imaging technique used to detect breast cancer, has an overdiagnosis problem. Doctors have long known that some portion of the tumors revealed by the scans might never become life-threatening--but they haven't been able to discern harmless growths from those that grow and spread.
June 8, 2017
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Women trust their own judgment when making breast cancer surgery-related decisions
A research team led by Breast Health Fellow Rebecca M. Kwait, MD, at the Breast Health Center at Women & Infants Hospital of Rhode Island, a Care new England hospital, recently presented research indicating that when faced with a decision on the type of surgery to have to remove breast cancer, more women trust their own judgment over the input of their surgeon and even their partner.
July 7, 2016
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Women with diabetes who use low-dose aspirin have reduced breast cancer risk
A new study of nearly 149,000 women with diabetes over 14 years showed an overall 18% reduced breast cancer risk for women who used low-dose aspirin compared to those who did not. The study design and results are published in an article in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.
June 8, 2017
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Women with more social connections have higher breast cancer survival, study shows
In a large study of women with invasive breast cancer, socially integrated women -- those with the most social ties, such as spouses, community ties, friendships and family members -- were shown to have significantly lower breast cancer death rates and disease recurrence than socially isolated women.
December 13, 2016
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Worldwide statistics on breast cancer: Diagnosis and risk factors
Breast cancer is the only cancer that is considered universal among women worldwide.
April 26, 2017
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Cervical Cancer

1 in 4 men have genital HPV infections that cause or are linked to cancer
Researchers suggest boosted vaccination as 45% of men overall had some type of HPV.
January 20, 2017
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2 Doses of HPV Vaccine Effective for Younger Teens
Global study supports revised regimen for those under 15
November 22, 2016
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Artificial intelligence image detection technique offers low-cost, improved screening for cervical cancer
Artificial intelligence--commonly known as A.I.--is already exceeding human abilities. Self-driving cars use A.I. to perform some tasks more safely than people. E-commerce companies use A.I. to tailor product ads to customers' tastes quicker and with more precision than any breathing marketing analyst.
April 24, 2017
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Cervical cancer just got much deadlier–because scientists fixed a math error
Past estimates forgot to exclude women who had their cervixes removed.
January 23, 2017
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Cervical cancer mortality rates may be underestimated
A new analysis reveals that for most women, the risk of dying from cervical cancer is higher than previously thought. Unlike prior estimates that also included women who had undergone a hysterectomy and were therefore no longer at risk, this analysis only included women with a cervix. the study also revealed significant racial differences in the risk of dying from cervical cancer.
January 23, 2017
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CPRIT awards $1.5 million grant to reduce burden of cervical cancer in West Texas
Navkiran Shokar, M.A., M.P.H, M.D., has received nearly $1.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) to reduce the burden of cervical cancer in West Texas.
March 8, 2017
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Fewer Cervical Cancer Tests After HPV Vaccine?
Less testing could reduce risk of false positives and save money, researchers say
October 17, 2016
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Henrietta Lacks Film Highlights Research Issues
The story of Henrietta Lacks, an African-American cervical cancer patient whose tumor cells changed the course of biomedical research, will debut on HBO on Saturday in a new movie starring Oprah Winfrey.
April 21, 2017
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HIV status may affect the progression of HPV infection to cervical pre-cancer
HIV-positive women were more likely to have human papillomavirus infection progress to pre-cancerous cervical lesions
June 1, 2017
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HPV vaccine as cancer prevention is a message that needs to catch on
New infection stats should be 'a wake-up call' to spur lagging vaccination rates
April 28, 2017
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HPV vaccine can decrease incidence of cervical pre-cancers among young women, research shows
Every 20 minutes, someone in the United States receives a cancer diagnosis related to human papillomavirus. HPV causes cancer of the cervix, anus and throat. the HPV vaccine can prevent infections causing most of these kinds of cancer if people receive it before being exposed to the virus.
September 29, 2016
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HPV vaccine could drastically reduce cervical and other cancers globally
The latest HPV vaccine could prevent most HPV infections -- and millions of cancers -- worldwide, according to new researchers.
June 12, 2017
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HPV Vaccine More Effective Than Thought: Study
Prevents lesions that could cause cervical cancer by 50 percent, researchers say
September 29, 2016
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HPV-Linked Cancers Still Climbing in U.S.
Majority of 39,000 annual cases are preventable, CDC says
July 7, 2016
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IMRT reduces risk of side effects, improves quality of life for endometrial and cervical cancer patients
Patients with cervical and endometrial cancer have fewer gastrointestinal and genitourinary side effects and experience better quality of life when treated with intensity-modulated radiation therapy than with conventional radiation therapy, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology. Women receiving IMRT reported significantly fewer bowel and bladder problems than those receiving conventional radiation treatment.
September 23, 2016
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Johns Hopkins researchers develop new, highly accurate urine test to predict risk for cervical cancer
Johns Hopkins Medicine specialists report they have developed a urine test for the likely emergence of cervical cancer that is highly accurate compared to other tests based on genetic markers derived directly from cervical tissue.
November 17, 2016
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More information on how cancer and sugar-sweetened beverages are link
A study suggests that age is an important factor in the association between cancer and sugar-sweetened beverages and recommends that intervention programs to reduce consumption of added sugar be focused on lower socio-economic status, young males, as well as cervical cancer survivors.
October 3, 2016
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New tech promises easier cervical cancer screening
'Pocket colposcope' removes need for speculum, may enable self-screening
May 31, 2017
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New study estimates overall prevalence of genital HPV infection among men in the U.S.
Human papillomavirus (HPV) infection is the most common sexually transmitted infection in the United States, as well as a cause of various cancers, and a new study published online by JAMA Oncology estimates the overall prevalence of genital HPV infection in men ages 18 to 59.
January 19, 2017
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Outcomes for girls without HPV vaccination in Japan
Certain age groups with greater risk of high HPV infection rates
September 12, 2016
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Pocket Colposcope for Cervical Cancer Screening by Anyone Anywhere
Scientists at Duke University have developed a handheld colposcope that can be used for cervical screening. The slender wand can be attached to a smartphone or laptop to display images of the cervix.
June 2, 2017
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Reduced radiation can maintain high cure rates in patients with HPV-related oropharyngeal cancers
Human papillomavirus-positive oropharynx cancers (cancers of the tonsils and back of the throat) are on rise. After radiation treatment, patients often experience severe, lifelong swallowing, eating, and nutritional issues. However, new clinical trial research shows reducing radiation for some patients with HPV-associated oropharyngeal squamous cell carcinomas can maintain high cure rates while sparing some of these late toxicities.
December 27, 2016
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Robot radiology: Low cost A.I. could screen for cervical cancer better than humans
Artificial intelligence--commonly known as A.I.--is already exceeding human abilities. Self-driving cars use A.I. to perform some tasks more safely than people. E-commerce companies use A.I. to tailor product ads to customers' tastes quicker and with more precision than any breathing marketing analyst.
April 24, 2017
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Robot radiology: Low cost A.I. could screen for cervical cancer better than humans
An artificial intelligence image detection method has the potential to outperform PAP and HPV tests in screening for cervical cancer; Low-cost technique could be used in less-developed countries, where 80 percent of cervical cancer deaths occur
April 24, 2017
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Scientists advance a novel urine test to predict high-risk cervical cancer
Specialists report they have developed a urine test for the likely emergence of cervical cancer that is highly accurate compared to other tests based on genetic markers derived directly from cervical tissue.
November 17, 2016
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Scientists get best view yet of cancer-causing virus HPV
New details of the structure of the human papillomavirus (HPV) may lead to better vaccines and HPV anti-viral medications, according to research.
January 23, 2017
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Specific HPV strain linked to better overall survival for oropharyngeal cancer patients
When it comes to cancer-causing viruses like human papillomavirus, or HPV, researchers are continuing to find that infection with one strain may be better than another.
September 28, 2016
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Study finds low cervical cancer screening rates among women with mental illness
Women enrolled in California's Medicaid program (Medi-Cal) who have been diagnosed with severe mental illness have been screened for cervical cancer at much lower rates than other women, according to a new study by researchers at UC San Francisco.
April 17, 2017
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TCGA study identifies genomic features of cervical cancer
Investigators with the Cancer Genome Atlas (TCGA) Research Network have identified novel genomic and molecular characteristics of cervical cancer that will aid in the subclassification of the disease and may help target therapies that are most appropriate for each patient.
January 24, 2017
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Two in every five people in the US carry Human Papilloma Virus
Latest estimates of the prevalence of the human papilloma virus (HPV) in the US were published this month. Among the adult population, genital HPV was identified in 45% of men and 40% of women. the prevalence of oral HPV was 11.5% among men and 3.3% among women.
April 7, 2017
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Two Staffordshire hospitals introduce pioneering technology to improve cervical cancer diagnosis
Two hospitals in Staffordshire have introduced a pioneering new technology designed to improve the speed and accuracy in diagnosing pre-cancerous conditions of the cervix.
October 5, 2016
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U.S. Cervical Cancer Deaths May be Underestimated
Rates rose when latest study excluded women who'd already undergone hysterectomy
January 23, 2017
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U.S. Vaccine Guidelines for Flu, HPV Updated
CDC panel revises immunization advisory for vaccines affecting adults
February 7, 2017
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Unwelcoming healthcare environments may affect cervical cancer screening among LGBT people
A new study found that certain factors affect cervical cancer screening among lesbian and bisexual women and transgender men. some of these factors overlap with the general female population, whereas others are specific to the lesbian, bisexual, or queer identity.
June 30, 2016
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Women should continue cervical cancer screening as they approach age 65
Adjusted rates for cervical cancer do not decline until age 85, signaling a need for ongoing surveillance, according to a new study
May 1, 2017
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Colon Cancer - Numbers

30% reduction in deaths from bowel cancer
The rate of new cases of bowel cancer in Austria has fallen by around 20% in the last ten years, while the associated mortality rate has fallen by nearly 30%. this trend is primarily due to improvements in preventive screening colonoscopy, in which precancerous stages are removed before the disease can take hold.
April 19, 2017
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Colon Cancer - A

Active hedgehog signalling in connective tissue cells protects against colon cancer
Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. a new study now surprisingly shows that in colon cancer hedgehog signalling has a protective function.
August 08, 2016
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Adhesive patch can deliver triple combination therapy to tumor sites
Approximately one in 20 people will develop colorectal cancer in their lifetime, making it the third-most prevalent form of the disease in the U.S. In Europe, it is the second-most common form of cancer.
July 25, 2016
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Adjuvant chemotherapy in early-stage colon cancer may improve survival
Researchers and physicians have grappled with the role of 'adjuvant,' or post-surgery, chemotherapy for patients with early-stage colon cancer, even for cancers considered high risk. now researchers have found an association between the use of adjuvant chemotherapy in stage 2 colon cancer and improved survival -- regardless of a patient's age or risk, or even of the specific chemotherapy administered.
July 15, 2016
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Adjuvant chemotherapy may improve survival in stage 2 colon cancer patients
Researchers and physicians have grappled with the role of "adjuvant," or post-surgery, chemotherapy for patients with early-stage colon cancer, even for cancers considered high risk. now researchers from the University of Illinois at Chicago have found an association between the use of adjuvant chemotherapy in stage 2 colon cancer and improved survival -- regardless of a patient's age or risk, or even of the specific chemotherapy administered.
July 15, 2016
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Answering the call for quality colorectal cancer patient info
Patients depend on the Internet for health information, but when it comes to colorectal cancer, currently available resources are not meeting their needs.
August 22, 2016
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Antibiotics may increase the risk of bowel cancer
According to a recent study published in the journal Gut, long-term use of antibiotics during adulthood increases the likelihood of developing precursors to bowel cancer. the research, once again, underlines the vital role of gut bacteria.
April 5, 2017
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Aspirin slows spread of colon, pancreatic cancer in tumor cells
Aspirin may slow the spread of some types of colon and pancreatic cancer cells, investigators have found. Their study looks at the interaction between aspirin and blood platelets in cancer cells.
December 14, 2016
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ASTRO clinical practice statement outlines recommendations to customize treatment for rectal cancer
The American Society for Radiation Oncology recently issued a new clinical practice statement, "Appropriate Customization of Radiation Therapy for Stage II and III Rectal Cancer: An ASTRO Clinical Practice Statement Using the RAND/UCLA Appropriateness Method." An executive summary of the guideline was published in the May-June 2016 issue of Practical Radiation Oncology, ASTRO's clinical practice journal, and the full guideline is available as an open-access online article in PRO.
July 21, 2016
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Colon Cancer - B

Blood Test May Predict Colon Cancer's Return
DNA-based screen would aid treatment decisions for people with early-stage disease
July 7, 2016
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Bowel cancer: new function of known biomarkers discovered
EGFR (Epidermal Growth Factor Receptors) are involved in the development and progression of many types of cancer and bowel cancer (colon carcinoma) in particular. So-called anti-EGFR antibodies are used in the treatment of bowel cancer patients, to inhibit EGFR. However, for reasons that are not yet clear, not all patients benefit from this treatment.
April 13, 2017
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Colon Cancer - C

CapsoCam Plus, a Swallowable Endoscope with Four Cameras FDA Cleared
CapsoVision won FDA clearance for its CapsoCam Plus swallowable capsule endoscope for imaging the small intestine. the device provides a 360� view of the bowels thanks to four cameras that capture photos as long as the pill is moving down the guts. Integrated flashes make sure the field of view is illuminated to see any abnormalities on the walls of the bowels.
November 14, 2016
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'Capsule Robot' May Guide Future Colon Check
Tiny, magnet-guided device might someday replace colonoscopy, researchers say
May 8, 2017
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Chance of colon cancer recurrence nearly cut in half in people who eat nuts
Something as simple as eating tree nuts may make a difference in the long-term survival of patients with colon cancer, a new study concludes.
May 18, 2017
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Chemo Overused in Younger Colon Cancer Patients?
Study found the treatment often wasn't beneficial, but cancer expert says more research is needed
January 25, 2017
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Clinical Genomics' blood test detects twice the number of colorectal cancer recurrence cases than CEA testing
Results underscore clinical utility of novel circulating tumor DNA assay to detect disease recurrence
October 14, 2016
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Clinical study reveals safety and efficacy of novel investigational colonoscopy prep
Detailed results from a Phase 2 study of a novel colonoscopy prep (ECP) under development by ColonaryConcepts, LLC show the investigational treatment to be at least as effective and safe as two currently available colonoscopy prep formulations, while offering a much higher level of patient satisfaction and preference than standard preps.
October 17, 2016
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Colon and rectal cancer seem to be on the rise–in millennials
And obesity is probably a culprit
February 28, 2017
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Colon cancer patients with healthy lifestyle have longer disease-free survival, study finds
A study of 992 patients with stage III colon cancer found that those who reported a healthy lifestyle during and following adjuvant (post-surgery) treatment had a 42% lower chance of death and a trend for lower chance of cancer recurrence than those who had less healthy lifestyles. The study will be presented at the upcoming 2017 ASCO Annual Meeting in Chicago.
May 18, 2017
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Colon Cancer Rising Among Gen Xers, Millennials
And an old adversary -- the obesity epidemic -- may be the cause, U.S. researchers say
February 28, 2017
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Colon Cancer's Location May Determine Survival
Study found 'right-sided' tumors had worse prognoses, with implications for screening and treatment
October 27, 2016
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Colonoscopy Probe for Diagnosing Inflammatory Bowel Disease
Researchers at Vanderbilt University developed a colonoscopy endoscope that performs Raman spectroscopy, giving it the power to spot molecules in the gut related to the presence of inflammatory bowel disease (IBD). Currently, diagnosis of IBD is an inexact science that typically requires the patient to try different therapies that eventually point to which type of IBD (ulcerative colitis or Crohn's disease) is present. this can take years in some cases, putting a great toll on people suffering from the disease before treatment options are identified.
January 5, 2017
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Colorectal cancer is on the rise among younger adults
Unhealthy lifestyle linked to increase in tumor incidence, death rates
March 1, 2017
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Colorectal Cancers on the Rise in Younger Adults
Three different doctors over 3 years dismissed Ashley Flynn's complaints.
November 30, 2016
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Colorectal tumors present epigenetic heterogeneity, study finds
A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program of Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at University of Barcelona discovers that colorectal tumors present epigenetic heterogeneity that relates to the clinical course of the disease.
August 18, 2016
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Common food additive promotes colon cancer in mice
Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study.
November 7, 2016
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Colon Cancer - D

Discovery of a novel gene for hereditary colon cancer
The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. the large-scale appearance of polyps is often due to a hereditary cause; in this case the disease can occur in multiple family members. now a team of researchers has discovered genetic changes in the MSH3 gene in patients and identified a new rare form of hereditary colon cancer.
July 28, 2016
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Discovery of a novel Wnt inhibitor with potential to eradicate colorectal cancer stem cells, report researchers
A team of researchers has announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. the inhibitor may provide a new therapy option for patients with drug-refractory colorectal cancer.
August 26, 2016
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Doctors Have Built a Magnetic Robot to Gently Explore your Colon
As you get older, colonoscopies become an important part of maintaining your health, allowing doctors to spot potentially fatal diseases like colon cancer before they progress too far. So medical researchers are hoping to make the procedure safer, and slightly less invasive, using a tiny capsule that's remotely steered around using a magnet outside your body.
May 9, 2017
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Does the microbiome play a role in the effectiveness of colorectal cancer treatment?
Connection between bacteria, chemotherapy discovered
April 24, 2017
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Colon Cancer - E

Edible Ginger-Derived Nano-Lipid can be Used to Treat Colon Cancer
According to a study conducted by researchers at the Institute for Biomedical Sciences at Georgia State University, Southwest University in China, and the Atlanta Veterans Affairs Medical Center and Wenzhou Medical University, nano-lipids that are derived from a particular group of edible ginger can be used to effectively target and deliver chemotherapeutic drugs that are used for colon cancer treatment.
September 12, 2016
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Engineered human colon model could aid in cancer research
A multi-institution collaboration has published research on a tissue-engineering method that allows forward genetics screening on human tissue. the team created a human colon model by first deleting cells from normal human colon tissue, while retaining most of the molecules to which the cells adhere. the tissue is then repopulated with cells obtained from colonoscopy patient samples and from commercial sources.
July 11, 2016
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Environmental enrichment triggers mouse wound repair response
Living in a stimulating environment has a wide range of health benefits in humans and has even been shown to fight cancer in mice, but the underlying mechanisms have been unclear. a study now reveals that cognitive stimulation, social interactions, and physical activity increase lifespan in mice with colon cancer by triggering the body's wound repair response.
April 25, 2017
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Experts join forces to study affordable malaria drug for treating colorectal cancer
Experts from St George's University of London, and St George's Hospital have joined forces to investigate whether a common and cheap malaria drug can be used also against cancer.
March 7, 2017
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Colon Cancer - F

Follow-up colonoscopies associated with a significantly lower incidence of bowel cancer
Patients at risk of developing bowel cancer can significantly benefit from a follow-up colonoscopy, finds new research.
April 28, 2017
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Colon Cancer - G

Genetic mutations found linked to rare cases of multiple bowel tumors
Researchers have identified genetic mutations affecting the immune system which may lead to the development of more than one bowel tumour at the same time. Understanding how these cancers develop could improve targeting of therapies, according to the new study.
July 5, 2016
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Colon Cancer - H

HCI receives $8.8 million NIH grant to lead colon cancer study
Huntsman Cancer Institute (HCI) at the University of Utah will head an international study to find out how lifestyle and other health factors impact colon and rectal cancer outcomes. HCI was awarded an $8.8 million grant from the National Institutes of Health to lead and expand an ongoing project in colon cancer research.
December 19, 2016
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Heart disease exercise program could work for bowel cancer patients
Could rehabilitation programs for heart disease patients be used to help people recovering from bowel cancer get back on their feet? That's the question cancer care experts have been exploring.
September 28, 2016
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Heart Risks May Boost Women's Colon Cancer Risk
This was true even in normal-weight women, study suggests
February 1, 2017
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Colon Cancer - I

Increasing the age limit for Lynch syndrome genetic testing may save lives
Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5 percent of all colon cancers.
May 29, 2017
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Interscope EndoRotor now Cleared in U.S. as new Way to Remove Colon Lesions
Interscope, a company out of Worcester, MA, landed FDA clearance for its EndoRotor device that, in a single step, dissects, resects, and retrieves mucosal lesions within the GI tract. In the U.S. the device is indicated for use within the colon, shaving off diseased mucosa in conjunction with endoscopic mucosal resectiont (EMR), and sucking up the debris to remove it from the body. These days lesions are typically removed using snares and forceps, tools that in many cases leave pieces of the targeted lesions intact.
May 4, 2017
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Is a new at-Home Colon Cancer Test for You?
Up to 40% of people who should get a test for colon cancer aren't doing so.
July 27, 2016
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Colon Cancer - L

Living healthy lifestyle could benefit men with high genetic risk of developing bowel cancer
Men with a high genetic risk of developing bowel cancer over the next 25 years could have a lower risk of developing the disease if they also have a healthy lifestyle, according to a Cancer Research UK-funded study published in the journal Genetics in Medicine today (Thursday).
September 29, 2016
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Loss of ARID1A protein drives onset, progress of colon cancer
How a tumor-suppressing protein interacts with genetic enhancers to silence cancer genes in a newly developed model system
December 12, 2016
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Colon Cancer - M

Many Dialysis Patients May not Need Colonoscopies
Study finds that a limited life span offsets the benefits of the screening test
March 24, 2017
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Many Early Colon Cancers Linked to Inherited Genes
One in 6 diagnosed under 50 has at least one gene mutation that ups risk, study says
December 14, 2016
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Colon Cancer - N

Nano-lipid particles from edible ginger could improve drug delivery for colon cancer
Edible ginger-derived nano-lipids created from a specific population of ginger nanoparticles show promise for effectively targeting and delivering chemotherapeutic drugs used to treat colon cancer, according to a study by researchers at the Institute for Biomedical Sciences at Georgia State University, the Atlanta Veterans Affairs Medical Center and Wenzhou Medical University and Southwest University in China.
September 6, 2016
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Nanotechnology research aimed at colorectal cancer receives $1.8 million in funding
Excluding skin cancers, colorectal cancer is the third most common cancer diagnosed in both men and women in the U.S. and second leading cause of cancer-related deaths.
July 28, 2016
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New analysis reveals high rate of colon cancer screening among dialysis patients
A new analysis reveals a relatively high rate of colon cancer screening among US patients on dialysis, even though they rarely stand to benefit from such screening. the findings appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN).
March 24, 2017
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New consensus guidelines on the management of metastatic colorectal cancer
Guidelines reflect personalized treatment approach
July 6, 2016
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New model could speed up colon cancer research
Introducing genetic mutations with CRISPR offers a fast and accurate way to simulate the disease
May 1, 2017
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New study shows hedgehog signalling offers protection against colon cancer
Many types of cancer are caused by gene mutations in the signalling pathways that control cell growth, such as the hedgehog signalling pathway. a new study from the Karolinska Institutet, published in the journal Nature Communications, now surprisingly shows that in colon cancer hedgehog signalling has a protective function.
August 08, 2016
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New web calculator could reliably predict chances of survival for bowel cancer patients
"How long do I have, doctor?" For many cancer patients, following the initial shock of their diagnosis, thoughts quickly turn to estimating how much precious time they have left with family and friends or whether certain treatments could prolong their life.
June 16, 2017
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New web calculator to more accurately predict bowel cancer survival
'How long do I have, doctor?' For many cancer patients, following the initial shock of their diagnosis, thoughts quickly turn to estimating how much precious time they have left with family and friends or whether certain treatments could prolong their life.
June 16, 2017
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Newly discovered DNA enhancers help switch on colorectal cancer
Study finds recurrent changes in DNA activate genes, promote tumor growth
March 7, 2017
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Novartis, Bristol-Myers Squibb collaborate to examine combination therapies for metastatic colorectal cancer
Novartis today announced it has entered into a clinical research collaboration in which Bristol-Myers Squibb will investigate the safety, tolerability, and efficacy of Mekinist (trametinib) in combination with Opdivo (nivolumab) and Opdivo + Yervoy (ipilimumab) regimen as a potential treatment option for metastatic colorectal cancer in patients with microsatellite stable tumors where the tumors are proficient in mismatch repair (MSS mCRC pMMR).
June 5, 2017
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Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients
A team including the National Cancer Center, the RIKEN Center for Life Science Technologies, and Carna Biosciences Inc. has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846. Wnt signaling is a key pathway of cancer stem cell development. the inhibitor may provide a new therapy option for patients with drug-refractory colorectal cancer.
August 26, 2016
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Colon Cancer - P

Patch delivers drug, gene, and light-based therapy to tumor sites
In mice, device destroyed colorectal tumors and prevented remission after surgery
July 25, 2016
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Patch delivers drug, gene, and light-based therapy to tumor sites
Approximately one in 20 people will develop colorectal cancer in their lifetime, making it the third-most prevalent form of the disease in the U.S. In Europe, it is the second-most common form of cancer.
July 25, 2016
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People diagnosed with bowel cancer under 50 not tested for Lynch syndrome, research finds
The UK's leading bowel cancer research charity, Bowel Cancer UK, and the Royal College of Pathologists have today published findings which show that people under 50 diagnosed with bowel cancer are not being tested for Lynch syndrome -- a genetic condition that increases the risk of bowel cancer by 80 per cent.
August 08, 2016
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Poor metabolic health in some normal-weight women may increase risk for colorectal cancer
Poor metabolic health associated with increased risk for colorectal cancer in normal-weight postmenopausal women
February 1, 2017
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Prognostic role of side where colon cancer occurs
Does the location of colon cancer -- left or right side -- matter for survival? a new report reviewed medical literature to examine the prognostic role of a primary colon cancer tumor being located on the left versus right side.
October 27, 2016
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Colon Cancer - R

Raising age limit for routine genetic testing in colorectal cancer could identify more cases of Lynch syndrome
Raising the age limit for routine genetic testing in colorectal cancer could identify more cases of families affected by Lynch syndrome, a condition that accounts for around 5% of all colon cancers, according to new research to be presented at the annual conference of the European Society of Human Genetics today (Monday). Professor Nicoline Hoogerbrugge, head of the Radboud university medical center expert center on hereditary cancers, Nijmegen, The Netherlands, will tell the conference that there is an urgent need to find families carrying a mutation for Lynch syndrome in order to decrease mortality from the disease.
May 29, 2017
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Regulatory T cells' involvement in the progress of colon cancer
Researchers have clarified that T-lymphocytes expressing FOXP3 at a low level found in colorectal cancers (CRCs) facilitated cancer immunity. FOXP3 is a master gene of Regulatory T (Treg) cells that suppress various immune responses including cancer immuity. they found that a certain intestinal bacteria species was involved in the induction of such FOXP3-low T cells enhancing tumor immunity. These findings suggest new potentials in the treatment of CRCs via regulation of intestinal bacteria.
July 5, 2016
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Research paves way for improved colorectal cancer test
Researchers have identified specific types of bacteria that seem to be abundant in individuals with colorectal cancer. Using a combination of markers specific for these fecal microbes, scientists anticipate that a noninvasive, sensitive clinical diagnostic test potentially can be developed.
April 19, 2017
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Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis
Venuprasad Poojary, PhD, an associate investigator at Baylor Institute for Immunology Research (BIIR), part of Baylor Scott & White Research Institute, reported this week in the journal Nature Immunology the role of a key protein in the regulatory pathway that is involved in limiting colon inflammation and tumor growth. the paper, titled "Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-gt ubiquitination," is available online in advance of the print edition.
June 30, 2016
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Researchers develop new computational method to track colorectal cancer progression
Team of researchers elaborated a computational method to track the progress of the colorectal cancer. It is a scientific advance that can bring new perspectives to discover the factors that push this pathology and the selection of efficient therapies.
June 29, 2016
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Researchers develop Triple-Therapy Hydrogel Patch to Treat Colorectal Cancer
It is believed that one in 20 people will develop colorectal cancer in their lifetime, which makes it the third-most common form of cancer in the U.S. In Europe, it is known to be the second-most common form of cancer.
July 27, 2016
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Researchers developing and validating model to predict risk for colon cancer in people under 50
While the incidence of colon cancer has been declining in individuals 50 years old and older in the United States, it is steadily rising in those under age 50. with funding from the U.S. Department of Veterans Affairs, Thomas F. Imperiale, M.D., a VA and Regenstrief Institute clinician-researcher, is developing and validating a model to predict risk for colon cancer in those under 50 with no family history of the disease.
July 21, 2016
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Researchers discover genetic changes in MSH3 gene in patients with hereditary colon cancer
The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. the large-scale appearance of polyps is often due to a hereditary cause; in this case the disease can occur in multiple family members. Under the leadership of human geneticists of the University Hospital Bonn, a team of researchers discovered genetic changes in the MSH3 gene in patients and identified a new rare form of hereditary colon cancer.
July 28, 2016
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Researchers find key to drug resistant bowel cancer
Blcoking a molecule could bypass bowel cancer's defense against the drug cetuximab, according to new research.
November 9, 2016
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Researchers identify odorant troenan that can inhibit colorectal cancer growth
Growth of colorectal cancer cells can be inhibited with the odorant troenan. this is reported by the research team headed by Prof Dr Dr Dr habil. Hanns Hatt and Dr Lea Weber from Ruhr-Universität Bochum in the journal "PLOS One". the researchers detected the olfactory receptor OR51B4 in tumour cells taken from the rectum and colon cancer cell lines. they analysed which odorant activates the receptor and in what way the activation affects the cells.
March 23, 2017
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Researchers Use Nanodiscs to Deliver Customized Therapeutic Vaccine for Cancer Treatment
Researchers at the University of Michigan have had initial success in mice using nanodiscs to deliver a customized therapeutic vaccine for the treatment of colon and melanoma cancer tumors.
December 27, 2016
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Retinoic acid suppresses colorectal cancer development, study finds
Levels of retinoic acid, a vitamin a metabolite, are low in mice and humans with colorectal cancer, according to new research. People with high levels of an enzyme that degrades retinoic acid have a poor prognosis, report researchers.
August 30, 2016
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Review highlights link between intestinal microbiota and colorectal cancer development
Recent evidence from animal models suggests a role for specific types of intestinal bacteria in the development of colorectal cancer (CRC). If a microbial imbalance in the gut could actively contribute to CRC in humans, dietary-based therapeutic interventions may be able to modify the composition of the gut microbiome to reduce CRC risk, as discussed in a review article published in BioResearch Open Access, a peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers.
December 9, 2016
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Colon Cancer - S

Scientists discover why some cancers may not respond to immunotherapy
Scientists have discovered that people with cancers containing genetic mutations JAK1 or JAK2, which are known to prevent tumors from recognizing or receiving signals from T cells to stop growing, will have little or no benefit from the immunotherapy drug pembrolizumab. this early-stage research has allowed them to determine for the first time why some people with advanced melanoma or advanced colon cancer will not respond to pembrolizumab, an anti-PD-1 treatment.
February 6, 2017
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Single-cell analysis pave way for more accurate cancer prognosis
For the first time, researchers have applied single-cell transcriptomics to colorectal cancer (CRC) -- the third most common cancer in the world -- and discovered that this method could lead to improved patient stratification and eventually, a more accurate prognosis of CRC patients
March 21, 2017
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Study shows effectiveness of 3 months of chemotherapy in colon cancer patients after surgery
"In this case, less is more. We're now able to spare many patients with colon cancer unnecessary side effects of an additional 3 months of chemotherapy without compromising results. This study is an excellent example of how existing treatments can be refined to work even better for patients," said ASCO Expert Nancy Baxter, MD.
June 5, 2017
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Study shows low incidence of cancer in patients with large colorectal polyps
For the majority of patients with large or difficult to remove colorectal polyps (growths in the colon), the incidence of cancer is actually lower than previously thought, and using more advanced endoscopic techniques that spare the colon may be a better, safer alternative to a traditional operation in certain cases, according to study results published online in the Journal of the American College of Surgeons in advance of print publication.
June 30, 2016
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Colon Cancer - T

Tree nuts may lower risk of colon cancer recurrence, death
Consuming at least 2 ounces of tree nuts every week may significantly reduce the risk of cancer recurrence for patients who have been treated for stage III colon cancer, and it could more than halve their risk of death.
May 18, 2017
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Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model
Investigators at Brigham and Women's Hospital have developed a hydrogel patch that can adhere to tumors in a preclinical model of colon cancer, delivering a local, combination treatment as the elastic gel breaks down over time. the new technique may allow clinicians to one day use diagnostic colonoscopy equipment to immediately deliver treatment without the need for open surgery at a later date.
July 29, 2016
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Triple-therapy patch delivers local treatment, prevents recurrence in colon cancer model
Investigators at Brigham and Women's Hospital have developed a hydrogel patch that can adhere to tumors in a preclinical model of colon cancer, delivering a local, combination treatment as the elastic gel breaks down over time. the new technique may allow clinicians to one day use diagnostic colonoscopy equipment to immediately deliver treatment without the need for open surgery at a later date
July 29, 2016
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Tumor DNA fragments in blood can help identify risk of colorectal cancer recurrence
Ludwig researchers working in collaboration with colleagues in Australia and the US have shown that fragments of tumor DNA circulating in the blood can be used to gauge the risk of colorectal cancer recurrence and the efficacy of chemotherapy following surgery.
July 7, 2016
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Colon Cancer - U

UA study questions safety and efficacy of selenium in reducing risk of colorectal cancer
A 12-year study led by a team of University of Arizona Cancer Center researchers is bringing into question the safety and efficacy of selenium, a popular nutritional supplement touted to combat and reduce the risk of colorectal cancer.
October 14, 2016
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UTHealth researchers identify less invasive way to screen for colorectal cancer
Specific strains of bacteria in the gut are significantly associated with colorectal cancer, according to a new study by researchers at the University of Texas Health Science Center at Houston School of Public Health. the study, which also identified a less invasive and less expensive way to screen for colorectal cancer, was recently published in the journal Gut.
April 18, 2017
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Colon Cancer - W

What is colorectal cancer? how does colon cancer differ from rectal cancer?
Colorectal cancer is a combined term to describe the malignant tumors that occur in the large intestine; the colon being the upper part of the large intestine and the rectum being the lowest part of the large intestine.
March 31, 2017
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Endometrial Cancer

Birth control pills may protect against some cancers for decades
When it comes to oral contraceptives, women often hear about the increased cancer risk they pose. a new study, however, finds that the using birth control pills may protect against certain cancers for at least 30 years.
March 27, 2017
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Less invasive hysterectomy for early-stage endometrial cancer finds clinical support
Researchers found similar rates of disease-free survival and no difference in overall survival among women who received a laparoscopic or abdominal total hysterectomy for stage I endometrial cancer, according to a study.
March 28, 2017
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Esophageal Cancer

Alcohol, Obesity Could Up Esophageal Cancer Risk
A third of cases would vanish if people stayed trim and didn't drink, cancer experts say
July 28, 2016
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Automatic Computer Vision System Detects Early Esophageal Cancer
At the Eidhoven University of Technology (TU Eindhoven) in the Netherlands, a research team has developed a computer vision system that has shown excellent results at identifying early neoplastic lesions, which develop into full blown esophageal cancer, in patients with Barrett's esophagus. Such lesions are very difficult to spot, and not many physicians have the training or the eye necessary to do so accurately and consistently.
July 6, 2016
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'Born to be bad' or 'born to be benign:' Testing cells for esophageal cancer risk
Genetically analyzing lesions in the food pipe could provide an early and accurate test for esophageal cancer, according to research. Barrett's Esophagus is a common condition that affects millions of people, although many are undiagnosed.
August 19, 2016
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Case Western Reserve University awarded $6 million grant to continue research on Barrett's Esophagus
The National Cancer Institute recently awarded a $6 million grant to the Case Comprehensive Cancer Center and Case Western Reserve University School of Medicine to continue research on Barrett's Esophagus, a potentially fatal condition caused by long-term acid reflux. Reflux can cause tissue lining the esophagus to transform into tissue similar to that found in the intestine, significantly increasing esophageal cancer risk.
May 31, 2017
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Discovery of the genes responsible for esophageal cancer common among Japanese
Study Opens up new possibilities in the development of new medical treatments
July 15, 2016
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Esophageal cancer: Loss of muscle mass represents a significant risk to survival
Esophageal cancer patients who suffer loss of muscle mass (sarcopenia) during neoadjuvant therapy (chemotherapy prior to surgery) survive, on average, 32 months less than patients with no sarcopenia, new research concludes.
February 14, 2017
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Esophageal cancers driven by 'marginal gain' rather than speed
Scientists have shown that unexpectedly, esophageal cancer cells do not divide faster than their normal neighbors. But unlike normal cells, the tumor cells produce slightly more dividing daughter cells than non-dividing ones, forming a tumor. the study could lead to the development of new treatments for cancers that do not respond to current therapies which target fast-growing cells.
August 22, 2016
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New detection method paves the way for 100 percent detection of esophageal cancer
Software almost on par with specialists in recognizing esophageal cancer
July 5, 2016
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New method uses computer to scan esophagus images for signs of esophageal cancer
Recognizing the early stages of esophageal cancer is difficult because it can easily be missed. TU Eindhoven has therefore been working with the Catharina Hospital in Eindhoven to develop a method to enable a computer to scan esophagus images for signs of esophageal cancer. with exceptional results: the computer recognizes early cancer with almost as much accuracy as top specialists, of which there is only a handful.
July 5, 2016
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Novel calculator more easily identifies patients who will benefit from neoadjuvant chemoradiation
A calculator to guide treatment choice in esophageal cancer has been developed by a team of researchers. the tool helps identify which patients may benefit from treatment before surgery.
March 2, 2017
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Oral cavity bacterium linked to development and progression of esophageal cancer
A type of bacterium usually found in the human mouth, Fusobacterium nucleatum (F. nucleatum), has been found to be related to the prognosis of esophageal cancer in Japanese patients by researchers from Kumamoto University, Japan. the bacteria are a causative agent of periodontal disease and though it can be found among the intestinal flora, it hasn't been the focus of much research until now.
December 9, 2016
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Researchers discover gene variant associated with esophageal cancer
A rare genetic mutation is associated with susceptibility to familial Barrett esophagus and esophageal cancer, according to a new study that set out to identify novel disease susceptibility variants in FBE in affected individuals from a large multigenerational family.
July 28, 2016
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Surprisingly long learning curve for surgeons operating on esophageal cancer
A surgeon who operates on esophageal cancer must have performed 60 operations to prevent any lack of experience adversely affecting the long-term survival of the patients, according to a major Swedish cohort study. the finding has potential significance for clinical practice.
March 8, 2016
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Treatment improved overall survival in elderly patients with early-stage esophageal cancer
Elderly patients with early-stage esophageal cancer that received treatment had an increased 5-year overall survival when compared to patients who received observation with no treatment.
April 27, 2017
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Head and Neck Cancer

Diabetes drug takes aim at cancer's fuel source
Shuts down cancer cell's primary way of making energy in patients with head and neck cancer
January 25, 2017
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Innovative approaches to improve personalized radiation therapy for head and neck cancer patients
Researchers are able to use the radiosensitivity index within a mathematical framework to select the optimum radiotherapy dose for each patient based on their individual tumor biology, outlines a new report.
May 31, 2017
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Moffitt researchers hope to improve personalized radiation therapy for head and neck cancer patients
Radiation therapy is one of the most common treatments used to fight cancer, with an estimated 500,000 people each year receiving radiation therapy either alone or in combination with other treatments. Patients are often treated with a "one-size-fits-all" approach of a particular radiation dose and schedule according to tumor type, location, and the stage of growth.
May 31, 2017
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New study provides most comprehensive picture to date of head and neck cancer stem cells
Cancer stem cells resist therapy and are a major cause of relapse, long after the bulk of a tumor has been killed. a University of Colorado Cancer Center study published in the Journal of the National Cancer Institute provides the most comprehensive picture to date of head and neck cancer stem cells, identifying genetic pathways that cancer stem cells hijack to promote tumor growth and visualizing the process of "asymmetric division" that allows a stem cell to create tumor tissue cells while retaining its own stem-like profile.
September 15, 2016
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Novel vaccine therapy can generate immune responses in patients with HPV-related head and neck cancer
A novel vaccine therapy can generate immune responses in patients with head and neck squamous cell carcinoma (HNSCCa), according to researchers at the Abramson Cancer Center of the University of Pennsylvania. The treatment specifically targets human papillomavirus (HPV), which is frequently associated with HNSCCa, to trigger the immune response.
May 31, 2017
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Scientists find link between makeup of individual's microbiome and head and neck cancer
In a sample study, researchers at Johns Hopkins say they have found an association between the makeup of an individual's microbiome and head and neck cancer, a finding that potentially advances the quest for faster and more accurate cancer diagnosis and therapy.
June 28, 2016
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T cell channel could be potential new target for treating head and neck cancers
Researchers at the University of Cincinnati (UC) have discovered that an ion channel, active within T cells (white blood cells), could be targeted to reduce the growth of head and neck cancers.
November 17, 2016
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UCLA-led research finds promising results for more personalized head and neck cancer treatment
Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS-variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.
December 23, 2016
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Kidney Cancer - Renal Cell Carcinoma

Investigational drug shows promise for hard-to-treat renal cancer
The investigational compound savolitinib appears to have antitumor activity in patients with c-MET-driven papillary renal cell carcinoma, according to the results of a phase II study released at the 2017 Genitourinary Cancers Symposium in Orlando, FL.
March 1, 2017
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Kidney cancer treatment: Potential for new classes of HIF inhibitors
New insights into the potential for new classes of HIF inhibitors to restore control of the hypoxia response -- representing the potential foundation of a new cancer-fighting strategy -- are the focus of recently published research.
September 13, 2016
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New drug beats standard therapy in advanced kidney cancer
An experimental kidney cancer drug outperformed the standard first-line therapy for patients with metastatic disease who are considered at risk for poorer than average outcomes, according to results of a randomized phase II clinical trial.
November 15, 2016
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New drug provides considerable added benefit in treating adults with advanced renal cell cancer
Nivolumab has been approved since April 2016 as a checkpoint inhibitor for the treatment of adults with advanced renal cell cancer who have already undergone prior therapy. In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined whether in these patients this monoclonal antibody offers advantages over the appropriate comparator therapy.
August 11, 2016
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Obesity linked to improved survival in kidney cancer
Obesity almost always increases cancer risk and worsens outcomes, but researchers report that overweight patients with advanced kidney cancer had significantly longer survival than those who were normal or underweight.
September 6, 2016
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Overweight People Fare Better with Kidney Cancer?
Study suggests they do, giving insights into potential new treatments
September 7, 2016
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Researchers identify potential biomarkers predictive of TKIs response in metastatic renal cancer
A team of CNIO researchers, in collaboration with the Spanish Oncology Genitourinary Group (SOGUG) and the University Hospitals Leuven (Belgium), has discovered various potential biomarkers predictive of tyrosine kinase inhibitors (TKIs) response in metastatic renal cancer. In their study, published in JCI Insight, the researchers identify various miRNAs that define a group of patients refractory to TKI treatment -a type of anti-angiogenic agent widely used to treat renal cell carcinoma- and with poor prognosis. the study, conducted on 139 patient samples, is the most robust to date in this tumour type.
July 8, 2016
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Researchers to explore potential roles of tumor-suppressor gene in kidney cancer
Renal cell carcinoma is the most common type of kidney cancer, and African-Americans and males appear most at risk for this disease that can be asymptomatic until it has spread and become highly lethal, said Dr. Vinata B. Lokeshwar, cancer researcher and chair of the Department of Biochemistry and Molecular Biology at the Medical College of Georgia at Augusta University.
October 7, 2016
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Liver Cancer - Hepatocellular Carcinoma

Advanced liver cancer: Selective internal radiation therapy safer than sorafenib
While advanced or inoperable hepatocellular carcinoma patients treated with selective internal radiation therapy showed similar overall survival to patients receiving sorafenib, it caused significantly fewer treatment-related adverse effects and delivered significantly better quality of life.
April 25, 2017
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CNIO study shows proinflammatory molecule IL-17A can be key factor in development of NASH and HCC
Non-alcoholic steatohepatitis (NASH) is a serious hepatic condition that precedes hepatocellular carcinoma (HCC) and is currently untreatable. a study conducted at the Spanish National Cancer Research Centre (CNIO) shows that a proinflammatory molecule, IL-17A, is a key factor in the development of this pathology, and points out that blocking IL-17A or inhibiting cells that secrete IL-17A with drugs such as digoxin (an antiarrhythmic agent) may be useful to prevent NASH in patients susceptible to develop HCC.
July 12, 2016
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Community outreach workers may help increase HBV vaccination rates to cut risk of liver cancer
Liver cancer is more common among Asian Americans in part because they are at high risk of HBV infection. One out of 12 Asian Americans carries the virus, accounting for more than half of the cases in the US. Although the HBV vaccine is now given at birth in many countries throughout the world, a large portion of Asian American adults remain unprotected and at risk for developing cancer, because the virus, which can cause liver cancer, is endemic in many Asian and Sub-Saharan African countries.
October 12, 2016
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Compound in aged cheese may prevent liver cancer, boost longevity
A new study suggests that there may be a simple way to help reduce the risk of liver cancer and extend lifespan: consume mushrooms, soy, whole grains, aged cheese, and other foods rich in spermidine.
April 24, 2017
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Digital assay of circulating tumor cells may improve diagnosis, monitoring of liver cancer
Use of an advanced form of the commonly used polymerase chain reaction method to analyze circulating tumor cells may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment.
January 19, 2017
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Drinking coffee daily may halve liver cancer risk
If you enjoy your morning cup of joe, the results of a recent study will be welcome news. Researchers have found that drinking just one cup of coffee per day could cut the risk of hepatocellular cancer - the most common form of liver cancer - by a fifth.
May 30, 2017
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Interferon-beta producing stem cell-derived immune cell therapy on liver cancer
Induced pluripotent stem (iPS) cell-derived myeloid cells (iPS-ML) that produce the anti-tumor protein interferon-beta (IFN-beta) have been produced and analyzed. Using human iPS-ML in a mouse model, they found that the cells migrate to and deliver IFN-beta to liver tumors thereby reducing cancer proliferation and increasing survival time.
March 28, 2017
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Liver tumor growth in mice slowed with new chemo-immunotherapy treatment
Researchers explore improved treatment strategies for hepatocellular cancer
February 28, 2017
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Low selenium levels linked to liver cancer risk? An interview with Dr David Hughes
What is selenium and what role does it play in the body?
August 22, 2016
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More Evidence Linking Obesity to Liver Cancer
And type 2 Diabetes more than doubles the odds, researchers say
October 14, 2016
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Nanotechnology Advancement for Minimally Invasive Treatment of Liver Cancer
The American Cancer Society reports that every year, over 700,000 new liver cancer cases are diagnosed globally.
November 30, 2016
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New analysis reveals low incidence of liver cancer in patients with cirrhosis
Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is four percent or lower.
February 1, 2017
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New minimally invasive surgery may soon be viable alternative to treat liver cancer
For patients who may benefit from a major liver operation to treat cancer, an open abdominal procedure is often the only option. However, a minimally invasive approach that avoids the large open incision may soon be a viable alternative, according to results from a multicenter study presented at the 2016 Clinical Congress of the American College of Surgeons (ACS).
October 18, 2016
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One more piece in the puzzle of liver cancer identified
Scientists are one step closer to unraveling the mechanisms behind liver cancer. the researchers discovered that RAF1, a protein known as an oncogene in other systems, unexpectedly acts as a tumour suppressor in hepatocellular carcinoma.
December 21, 2016
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Regorafenib drug improves survival rates in patients with hepatocellular carcinoma
Oral multikinase inhibitor regorafenib achieves significantly improved survival rates compared to placebo in patients with hepatocellular carcinoma, according to data from the phase III RESORCE trial, presented at the ESMO 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.
June 30, 2016
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Researchers aim to examine therapeutic effect of iPS-ML producing interferon-β on liver cancer
All causes of the most common form of liver cancer, hepatocellular carcinoma (HCC), are not yet known, but the risk of getting it is increased by hepatitis B or C, cirrhosis, obesity, diabetes, a buildup of iron in the liver, or a family of toxins called aflatoxins produced by fungi on some types of food.
March 29, 2017
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These jolly, candy-colored 3D-printed livers help doctors treat tumors
The liver is a wonderful thing. It goes great on crackers and it can keep your blood from becoming septic. But it's almost impossible to operate on that strange, fleshy mass without lots of luck and preparation. Luckily there's now a better way to prepare.
March 7, 2017
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Tracking unstable chromosomes helps predict lung cancer's return
Scientists have found that unstable chromosomes within lung tumors increases the risk of cancer returning after surgery, and have used this new knowledge to detect relapse long before standard testing.
April 26, 2017
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Lung Cancer - A

A biosensor is able to detect tumors at early stages
Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer antibodies. a biosensor developed by scientists from the Complutense University of Madrid has been able to detect these defensive units in serum samples of patients with colorectal and ovarian cancer. the developed method is faster and more accurate than traditional methods.
January 11, 2017
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A novel cancer immunotherapy shows early promise in preclinical studies
GARP could be a novel diagnostic marker for cancer and targeting it with an antibody prevented metastasis to the lungs in a mouse model of breast cancer, report scientists at the Medical University of South Carolina in an article in Cancer Research
January 11, 2017
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Active agent from the Caribbean sea cucumber could improve treatment for malignant pleural mesothelioma
Researchers have discovered a new option for treating malignant pleural mesothelioma. for the first time in the world, they were able to show in a preclinical study, both in the cell culture and in the animal model, that trabectedin, a chemotherapy drug that is already successfully used for other types of cancer, is also effective against malignant pleural mesothelioma. the active agent originally occurs in the Caribbean sea cucumber, a marine-dwelling tunicate.
October 22, 2016
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Added benefit of lung cancer drug not proven, says IQWiG
Afatinib (trade name: Giotrif) has been approved since April 2016 for the treatment of adults with locally advanced or metastatic non-small cell lung cancer (NSCLC) of squamous histology who have already received chemotherapy. In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined whether in these patients this drug offers advantages over the appropriate comparator therapy. According to the findings, an added benefit of afatinib for these patients is not proven.
August 19, 2016
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Advanced form of proton therapy shows promise for treating lung cancer recurrence
Few curative options exist for treating recurrent disease
March 17, 2017
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Advanced image analysis technique identifies genetic cell mutations in patients with lung cancer
Researchers have used positron emission tomography (PET) to successfully identify genetic cell mutations that can cause lung cancer. the research, published in the featured article of the April 2017 issue of "The Journal of Nuclear Medicine," shows that an advanced image analysis technique, radiomics, can non-invasively identify underlying cell mutations in patients with non-small cell lung cancer (NSCLC). More people in the United States die from lung cancer than from any other type of cancer, and NSCLC is the most common form.
April 3, 2017
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AI beats doctors at visual diagnosis, observes many times more lung cancer signals
A new study from Stanford University could ruffle feathers in the medical community, as the researchers report that their newly developed machine learning algorithm can identify tissue slides exhibiting a specific type of cancer with far greater accuracy than human epidemiologists. it's one of the first indications that computers aren't just capable of addressing the "subjective" portions of medicine, but that they're actually better suited to such problems than human doctors, in some cases.
August 18, 2016
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Artificial Stem Cells Promote Tissue Healing Minus Side Effects
A collaboration between researchers at North Carolina State University, the University of North Carolina at Chapel Hill, and First Affiliated Hospital of Zhengzhou University have apparently created a synthetic mimic of cardiac stem cells. These may end up being used instead of natural stem cells while reducing or eliminating side effects that may arise from stem cell therapy.
January 12, 2017
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Lung Cancer - B

Biologists identify key step in lung cancer evolution
Blocking the transition to a more aggressive state could offer a new treatment strategy
May 10, 2017
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Blood test could predict best treatment for lung cancer
A blood test could predict how well small-cell lung cancer (SCLC) patients will respond to treatment, according to new research.
November 21, 2016
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Bronchial carcinoma: Added benefit of crizotinib not proven
Dossier contains no data or no suitable data on ROS1-positive NSCLC
January 11, 2017
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Lung Cancer - C

Checkpoint inhibitor for treatment of NSCLC patients shows indication of added benefit
Nivolumab has been approved since April 2016 as a checkpoint inhibitor for the treatment of adults with locally advanced or metastatic nonsquamous non-small-cell lung cancer (NSCLC) who have already undergone chemotherapy. In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined whether in these patients this monoclonal antibody offers advantages over the appropriate comparator therapy.
August 19, 2016
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Chinese patient is first to be treated with CRISPR-edited cells
Chinese scientists have injected a person with CRISPR/Cas9-edited cells, marking the first time cells altered with the technique have been used in humans. Researchers used the powerful gene editor to alter immune cells to fight lung cancer, Nature reports November 15.
November 16, 2016
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Chinese startup Infervision emerges from stealth with an AI tool for diagnosing lung cancer
Roughly 600,000 people in China die from lung cancer every year. Already the leading cause of death in the pollution-choked and chain-smoking-prone nation, the incidence of lung cancer among China's citizens is actually going to increase to 800,000 cases per year by 2020.
May 8, 2017
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Combined FISH, IHC identifies patients with rare ALK Fusions that respond to crizotinib
The combined use of fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) identified non-small cell lung cancer (NSCLC) patients with rare or novel anaplastic lymphoma kinase (ALK) gene rearrangements, not otherwise identified by FISH alone, that showed response to crizotinib treatment.
September 12, 2016
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Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows
Computers can be trained to be more accurate than pathologists in assessing slides of lung cancer tissues, according to a new study by researchers at the Stanford University School of Medicine.
August 16, 2016
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Computers trounce pathologists in predicting lung cancer type, severity, researchers find
Computers can be trained to be more accurate than pathologists in assessing slides of lung cancer tissues, according to a new study. the researchers found that a machine-learning approach to identifying critical disease-related features accurately differentiated between two types of lung cancers and predicted patient survival times better than the standard approach of pathologists classifying tumors by grade and stage.
August 16, 2016
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Convincing Lung Cancer to Commit Suicide
Researchers Have Developed a Method to Kill Lung Carcinomas Using a Viral 'Suicide Gene'
June 28, 2016
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Could 'Safer' Filtered Cigarettes Be More Deadly?
New report suggests they're tied to rising rates of an aggressive lung cancer
May 22, 2017
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Lung Cancer - D

Delayed Chemo can Still Benefit in Lung Cancer
Patient recovery may mean longer time to the treatment, but study suggests it can still have benefit
January 6, 2017
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Drug offers some Hope for a Deadly Lung Cancer
Immunotherapy may triple 5-year survival rate for certain patients with advanced disease, study finds
April 4, 2017
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Drug-loaded synthetic nanoparticles can distinguish lung cancer cells from healthy cells
Researchers with the Harold C. Simmons Comprehensive Cancer Center successfully developed a synthetic polymer that can transport a drug into lung cancer cells without going inside of normal lung cells.
September 15, 2016
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Lung Cancer - F

Fear of diagnostic low-dose radiation exposure is overstated, experts assert
Researchers assert that exposure to medical radiation does not increase a person's risk of getting cancer. the long-held belief that even low doses of radiation, such as those received in diagnostic imaging, increase cancer risk is based on an inaccurate, 70-year-old hypothesis, according to the authors.
January 9, 2017
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First immunotherapy for mesothelioma on the horizon, early research suggests
Malignant pleural mesothelioma or MPM is a rare cancer, but its incidence has been rising. This cancer is usually associated with asbestos exposure, and patients have a median life expectancy of only 13-15 months. All patients relapse despite initial chemotherapy, more than 50% of them within six months after stopping treatment. There are currently no effective therapeutic options for patients with MPM.
June 5, 2017
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First Use of Gene Editing Technique in Humans
The first use of a new gene-editing technique in humans has been reported by Chinese scientists.
November 16, 2016
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Lung Cancer - G

Gene-Targeted Drugs Fight Advanced Lung Cancers
Medications show promise for non-small cell type
June 5, 2017
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Lung Cancer - H

Having children at home did not prompt parents to test for radon, secondhand smoke
More awareness needed on home environmental exposures that cause lung cancer
August 30, 2016
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How cancer cells flood the lung
Lung cancer patients are particularly susceptible to malignant pleural effusion, when fluid collects in the space between the lungs and the chest wall. Researchers have discovered a novel mechanism that causes this to happen. Their study also shows that various active substances could potentially be used to treat this condition.
May 19, 2017
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Lung Cancer - I

Immunotherapy drug gives non-small-cell lung cancer patients extra four months of life with fewer side effects compared to chemotherapy
Patients with advanced non-small-cell lung cancer survive four months longer with fewer side effects on an immunotherapy drug called atezolizumab compared to chemotherapy, according to a phase 3 clinical trial.
December 13, 2016
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Introduction of CT lung screening for high-risk individuals could decrease cancer-related deaths
The introduction of lung cancer screening in the UK could significantly reduce deaths in high risk groups, without causing participants the undue stress sometimes associated with medical tests.
July 28, 2016
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Introduction of screening could significantly reduce lung cancer deaths
The introduction of lung cancer screening in the UK could significantly reduce deaths in high risk groups, without causing participants the undue stress sometimes associated with medical tests, say authors of a new report.
July 28, 2016
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Invasive lung cancer cells display symbiosis: Key to metastasis
Leader cells pull along supportive followers
May 12, 2017
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Lung Cancer - L

Large-scale cancer gene profiling is feasible but faces barriers
Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer.
November 17, 2016
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Largest genome-wide study of lung cancer susceptibility identifies new causes
A huge study identified several new variants for lung cancer risk that will translate into improved understanding of the mechanisms involved in lung cancer risk.
June 13, 2017
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Light cigarettes have likely contributed to rise of lung adenocarcinoma, study shows
A new study shows that so-called "light" cigarettes have no health benefits to smokers and have likely contributed to the rise of a certain form of lung cancer that occurs deep in the lungs.
May 22, 2017
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Liquid Biopsy for Lung Cancer Provides Rapid Results at Low Cost and No Trauma
Lung cancers tend to develop rapidly, changing how they respond to medication in unexpected ways. this makes it hard to decide which treatments are most effective without trying them first, resulting in lost time and missed opportunities. Biopsies and CT scans are the most commonly used methods of evaluating whether a treatment is working. Biopsies are invasive and can only be done infrequently, while CT scans offer limited information and expose the patient to X-ray radiation.
January 4, 2017
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Lung biopsy procedure: What to expect
A lung biopsy procedure is a type of medical operation, often involving removing tissue or growths from the lungs.
June 12, 2017
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Lung cancer and shoulder pain: What's the connection?
Most people experience shoulder pain, usually due to inflammation or muscle injuries. Much less frequently, shoulder pain can be a sign of lung cancer.
March 14, 2017
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Lung cancer complications: Signs, treatment, and outlook
Cancer is a disease caused by unhealthy cells inside the body growing out of control. Lung cancer is the uncontrolled growth of abnormal cells that start off in one or both lungs.
March 22, 2017
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Lung cancer patients may benefit from delayed chemotherapy after surgery
Patients with a common form of lung cancer may still benefit from delayed chemotherapy started up to four months after surgery, according to a team of researchers.
January 5, 2017
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Lung cancer in pictures: what does it look like?
Lung cancer can be a worrying diagnosis. this type of cancer is aggressive and can quickly spread to other organs, such as the pancreas and liver.
March 23, 2017
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Lung-Sparing Surgery May Up Mesothelioma Survival
Treatment nearly doubled survival or more, study finds
December 23, 2016
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Lymph node stage may have clinical significance among NSCLC patients with stage IV M1a
Analysis of a large non-small cell lung cancer (NSCLC) patient cohort with stage IV M1a disease identified lymph node staging as having clinical significance and an impact on prognosis.
August 24, 2016
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Lung Cancer - M

Mayo Clinic researchers identify genetic promoter that drives lung cancer formation
Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. In a new paper published this week in Cancer Cell, Mayo Clinic researchers provide genetic evidence that Ect2 drives lung adenocarcinoma tumor formation.
January 19, 2017
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Melanoma drug offers considerable added benefit for patients with advanced NSCLC
Pembrolizumab was initially introduced for the treatment of melanoma. Since July 2016, the monoclonal antibody has also been available for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in adults whose tumours express the T-cell receptor ligand PD-L1 and who have received a prior chemotherapy regimen. the German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether the drug offers an added benefit over the appropriate comparator therapy also for these patients.
November 22, 2016
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Mesothelioma shows promising response to existing immunotherapy drug
An existing immunotherapy drug called pembrolizumab appears to be effective in the treatment of malignant pleural mesothelioma, a rare and aggressive lung cancer that is primarily caused by exposure to asbestos. Writing in the Lancet Oncology, researchers describe the first study to show a positive result from using the antibody drug against this rare cancer.
March 31, 2017
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Mesothelioma: New trial to fight cancer caused by asbestos
Patients with a hard-to-treat type of cancer are being given new hope in a ground-breaking clinical trial.
May 19, 2017
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Metastatic lung cancer: Symptoms, diagnosis, and treatment
While cancer may develop in one area of the body, it has the ability to spread to other areas. When cancer spreads in this way, it is said to have metastasized, and is known as metastatic cancer.
March 16, 2017
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Moffitt research underscores importance of continued lung cancer screening in high-risk patients
Lung cancer is the leading cause of cancer death for men and women. It is also one of the most complex cancers, both at the molecular level and through its clinical behavior. Screening is paramount as it helps physicians diagnose and treat the disease in its earliest stages.
August 18, 2016
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Lung Cancer - N

Nanoelectronic barcoding on lab on a chip could monitor health, germs and pollutants
Imagine wearing a device that continuously analyzes your sweat or blood for different types of biomarkers, such as proteins that show you may have breast cancer or lung cancer.
June 12, 2017
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Nanoparticle exposure can trigger dormant viruses in lung tissue cells
Nanoparticles from combustion engines can activate viruses that are dormant in lung tissue cells. this is the result of a study by researchers of Helmholtz Zentrum M�, a partner in the German Center for Lung Research (DZL), which has now been published in the journal 'Particle and Fibre Toxicology'.
January 16, 2017
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Nasal Swab Shows Promise in Confirming Lung Cancer
Simple technique is based on cancer DNA and seems accurate for use after chest CT scan, researchers say
February 27, 2017
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Necitumumab drug shows minor added benefit in patients with metastatic NSCLC
The monoclonal antibody necitumumab has been approved since February 2016 for the treatment of patients with locally advanced or metastatic epidermal growth factor receptor (EGFR) expressing non-small cell lung cancer (NSCLC) who have not received prior chemotherapy for this condition. the drug is used in combination with gemcitabine and cisplatin.
July 5, 2016
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New blood test offers potential for faster, targeted treatment of non-small-cell lung cancer
Identification of 'actionable mutations' within 72 hours can shorten lag time between diagnosis and optimal treatment, reports the Journal of Molecular Diagnostics
April 19, 2017
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New FDA-approved drug helps patients fight against late-stage lung cancer
A new drug has been approved by the FDA in the fight against lung cancer. Tecentriq is being used by patients like Cornelius Bresnan, who had late-stage cancer.
December 2, 2016
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New genetic markers linked to fast rate of nicotine metabolism in smokers may raise risk for lung cancer
University of Hawai'i Cancer Center researchers discovered new genetic markers associated with a fast rate of nicotine metabolism, which potentially leads smokers to smoke more, thereby, increasing their risk for lung cancer.
August 25, 2016
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New lung scanning platform holds potential to improve treatment for people with lung disease
New lung scanning technology developed at Monash University has the potential to transform treatment for millions of people with lung disease in Australia and around the world.
August 05, 2016
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New therapeutic targets for small cell lung cancer identified
Researchers have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.
July 21, 2016
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New way to inhibit development of lung cancer
Medical researchers have found that inhibiting a protein called BMI1 could inhibit the development of lung cancer.
August 05, 2016
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Non-small cell lung cancer: Treatment, symptoms, and outlook
There are two main types of lung cancer: non-small cell lung cancer and small cell lung cancer.
March 17, 2017
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NSCLC patients treated with surgery may benefit from delayed chemotherapy, study shows
A new study suggests patients who recover slowly from non-small-cell lung cancer (NSCLC) surgery may still benefit from delayed chemotherapy started up to four months after surgery, according to a new study published online by JAMA Oncology.
January 5, 2017
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Lung Cancer - O

Oxygen can impair cancer immunotherapy in mice
Researchers have identified a mechanism in mice by which anticancer immune responses are inhibited within the lungs, a common site of metastasis for many cancers. this mechanism involves oxygen inhibition of the anticancer activity of T cells. Inhibiting the oxygen-sensing capability of immune cells, either genetically or pharmacologically, prevented lung metastasis.
August 25, 2016
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Lung Cancer - P

Pancoast syndrome: Tumors, symptoms, and treatment
Pancoast syndrome is the term given to the unique set of symptoms that accompany a Pancoast tumor - a type of lung cancer.
March 8, 2017
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Pembrolizumab shows promise in treatment of mesothelioma
Pembrolizumab, an antibody drug already used to treat other forms of cancer, can be effective in the treatment of the most common form of mesothelioma, according to a new study. the work is the first to show a positive impact from checkpoint inhibitor immunotherapy drugs on this disease.
March 19, 2017
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Pneumonia and lung cancer: Symptoms, diagnoses, and treatments
Pneumonia and lung cancer both occur in the lungs and share a number of overlapping symptoms.
April 7, 2017
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Prototype drug uses novel mechanism to treat lung cancers
Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein, report researchers in a new article.
May 16, 2017
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Public reporting of lung cancer surgery outcomes provides valuable information about quality of patient care
The first publicly accessible national report of outcomes from lobectomy has now been released by experts.
January 19, 2017
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Lung Cancer - R

Report describes VHA clinical demonstration project for lung cancer screening
Implementing a comprehensive lung cancer screening program was challenging and complex according to a new article that describes a lung cancer demonstration project conducted at eight academic Veterans Health Administration hospitals.
January 30, 2017
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Research findings unveil new avenues to monitor, treat lung cancer more effectively
A team of researchers from Singapore has discovered a class of small RNA molecules, known as oncomiRs, which are responsible for fuelling lung cancer. Published in Nature Communications, the findings provide fresh insight into understanding therapy resistance in lung cancer and unveil new avenues to monitor and treat the disease more effectively.
July 12, 2016
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Research shows cellular component may play vital role in how lung cancer spreads
A cellular component known as the Golgi apparatus may play a role in how lung cancer metastasizes, according to researchers at the University of Texas MD Anderson Cancer Center whose findings were reported in the Nov. 21 online issue of the Journal of Clinical Investigation.
November 21, 2016
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Researchers focus on optimal use of immune agents in frontline setting for NSCLC treatment
Immunotherapy continues to revolutionize the field of non-small cell lung cancer (NSCLC), with researchers now focusing on the optimal use of immune agents in the frontline setting.
November 18, 2016
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Researchers identify mechanism of oncogene action in lung cancer
Researchers have identified a genetic promoter of cancer that drives a major form of lung cancer. In a new paper, researchers provide genetic evidence that Ect2 drives lung adenocarcinoma tumor formation.
January 19, 2017
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Researchers identify tantalizing target in fight against aggressive form of lung cancer
Researchers at the University of Virginia School of Medicine have discovered a flaw in the armor of the most aggressive form of lung cancer, a weakness that doctors may be able to exploit to slow or even stop the disease. Remarkably, this vulnerability stems from the very aggressiveness that makes the cancer so deadly.
August 19, 2016
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Researchers inhibit tumor growth in new subtype of lung cancer
Insight into tumor suppressing and tumor promoting mechanisms offers potential for new treatments
August 03, 2016
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Revolutionary surgery for lung cancer
A major international clinical trial is about to be launched to test a minimally invasive and safer surgical approach for patients with lung cancer: video-assisted thoracoscopic (VATS) lobectomy with ultrasonic pulmonary artery sealing.
July 11, 2016
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Lung Cancer - S

Scientists identify 'cellular post office' that could be key to preventing spread of lung cancer
Scientists at the Universities of York and Texas have found that a component of cancer cells, which acts like a 'cellular post office', could be the key to preventing the spread of lung cancer to other parts of the body.
November 24, 2016
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Scientists identify new way to impair tumour growth in lung cancer
Researchers from the Cancer Science Institute of Singapore at the National University of Singapore, in collaboration with Harvard Stem Cell Institute, have discovered a new way in which the development of lung cancer can be stopped. In a study published in the journal Science Translational Medicine in August 2016, the researchers found that inhibiting a protein called BMI1 was able to impair tumour growth in lung cancer.
August 05, 2016
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Scientists step closer to halting spread of lung cancer
A component of cancer cells, which acts like a 'cellular post office', could be the key to preventing the spread of lung cancer to other parts of the body, scientists have discovered.
November 24, 2016
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Short and long sleep, and sleep disturbances associated with increased risk of dementia and lung cancer
Difficulties in initiating or maintaining sleep at middle-age are associated with an increased risk of dementia, according to a new study. The 20-year follow-up study was conducted among 2,682 men participating the Kuopio Ischaemic Heart Disease Study.
May 24, 2017
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Smokers with newly discovered genetic markers have higher lung cancer risk
Researchers discovered new genetic markers associated with a fast rate of nicotine metabolism, which potentially leads smokers to smoke more, thereby, increasing their risk for lung cancer.
August 25, 2016
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Smog May Shorten Lives of Lung Cancer Patients
Large review in California finds lower survival rates among those with most exposure to dirty air
August 05, 2016
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Small cell lung cancer: Symptoms, treatment, and outlook
Small cell lung cancer is characterized by the presence of cancerous tumor cells in the lung tissues.
March 19, 2017
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Small cell versus non-small cell lung cancer: what are the differences?
Small cell and non-small cell are the two types of lung cancers. Both cancers affect the lungs but they have several key differences, including how they are treated and their average progression time.
March 21, 2017
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Some lung cancer patients benefit from immunotherapy even after disease progression
Some advanced lung cancer patients benefit from immunotherapy even after the disease has progressed as evaluated by standard criteria, according to new research. the findings pave the way for certain patients to continue treatment if the disease is not progressing according to new, more specific, criteria.
May 4, 2017
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Stage 3 lung cancer: Symptoms, treatment, and outlook
Stage 3 lung cancer is often described as late, locally advanced or advanced lung cancer.
March 19, 2017
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Stages of lung cancer: Symptoms, changes, and outlook
There are two main types of lung cancer: non-small cell lung cancer and small cell lung cancer. Each has its own system of staging, a process that determines the extent to which a cancer has spread.
March 6, 2017
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STS releases first publicly accessible report of outcomes from lung cancer surgery
The Society of Thoracic Surgeons (STS) has released the first publicly accessible national report of outcomes from lobectomy, a lung cancer procedure that removes a portion of the lung. the surgical outcomes data are from the Society's General Thoracic Surgery Database (GTSD), one of three components in the world-renowned STS National Database, which is widely considered the gold standard for medical specialty outcomes databases.
January 20, 2017
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Study compares survival outcomes of two recommended lung cancer staging strategies
In a study appearing in the September 13 issue of JAMA, Jouke T. Annema, M.D., Ph.D., of the Academic Medical Center, Amsterdam, and colleagues examined five-year survival after endosonography vs mediastinoscopy for mediastinal nodal staging of lung cancer.
September 13, 2016
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Study examines survival outcomes after different lung cancer staging methods
Accurate mediastinal nodal staging is crucial in the management of non-small cell lung cancer (NSCLC) because it directs therapy and has prognostic value. now researchers have examined five-year survival after endosonography vs mediastinoscopy for mediastinal nodal staging of lung cancer.
September 13, 2016
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Study finds neoadjuvant immunotherapy safe, viable for early lung cancer patients before surgery
Neoadjuvant immunotherapy with the PD-1 inhibitor nivolumab is safe and feasible prior to surgery for early lung cancer, researchers reported at the ESMO 2016 Congress in Copenhagen.
October 7, 2016
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Study highlights importance of regular lung cancer screenings for those at high risk
Researchers found that patients who initially screened negative for lung cancer but developed the disease one to two years later had more aggressive disease
August 18, 2016
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Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations
Leptomeningeal metastases, a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer patients with epidermal growth factor receptor mutations. Patients receiving tyrosine kinase inhibitors targeting EGFR mutations had a longer overall survival than those who did not receive TKIs, demonstrating the effectiveness of TKIs for LM therapy.
August 16, 2016
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Suicide risk elevated among lung cancer patients
Of all cancers, people with lung cancer are at greatest risk of committing suicide, finds new research presented at the American Thoracic Society's 2017 international conference.
May 24, 2017
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Lung Cancer - T

Targeting low-oxygen patches inside lung cancer tumors could help prevent drug resistance
Mathematical model suggests ideal treatment schedule to eradicate tumors in one lung cancer subtype
August 25, 2016
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This May Up Survival for some Lung Cancer Patients
2 new studies find benefit to using stereotactic body radiation therapy
September 23, 2016
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To screen or not to screen for lung cancer?
Counseling and shared decision-making visit helps high-risk individuals decide
March 13, 2017
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Lung Cancer - U

Using a genetic signature to overcome chemotherapy-resistant lung cancer
Patients with non-small cell lung cancer (NSCLC) often respond to standard chemotherapy, only to develop drug resistance later, and with fatal consequences. But what if doctors could identify those at greatest risk of relapse and provide a therapy to overcome or avoid it?
May 23, 2017
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Lung Cancer - W

White blood cell count predicts response to lung cancer immunotherapy
White blood cell counts can predict whether or not lung cancer patients will benefit from immunotherapy, according to new research.
May 4, 2017
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Whole brain radiotherapy offers no quality-of-life benefit in lung cancer patients with brain metastases
People with the most common type of lung cancer whose disease has spread to the brain could be spared potentially harmful whole brain radiotherapy, according to new research published in the Lancet. the phase 3 randomised trial found that whole brain radiotherapy had no beneficial effect on length or quality of survival over treatment with steroids and other supportive care.
September 6, 2016
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Lung Cancer - Y

Yale researchers discover new blocking mechanism to inhibit lung tumors
Lung cancer cell growth depends on certain proteins that require the addition of sugar molecule chains to become active. Scientists have long thought that the addition of these sugar chains is like an on or off switch, and that blocking their addition would be harmful. now a Yale-led research team has identified a new blocking mechanism that acts more like a dimmer switch and potently inhibits lung tumor cell growth.
October 4, 2016
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Misc. - Numbers

4 in 10 U.S. Adults Under 60 Carry HPV
But vaccine should turn the tide against virus that can cause cancer, sexual health expert says
April 6, 2017
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10 ways tech is improving cancer research
New advances in cancer diagnosis and treatment leverage AI, IBM Watson, CRISPR, and even NASA tools to help detect and beat the disease.
September 22, 2016
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107 cancer papers retracted due to peer review fraud
New papers were found through investigations into previous fraud.
April 21, 2017
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Misc. - A

A better way to measure the stiffness of cancer cells
Laser technique peers through individual cells to gauge stiffness with unprecedented speed
February 28, 2017
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A gene's journey from covert to celebrated
Unmasking a previously misunderstood gene, scientists discover an unlikely potential drug target for gastrointestinal cancers.
January 23, 2017
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A glow stick that detects cancer?
Researchers devise a novel probe to identify and measure microscopic cell activity
May 1, 2017
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A mechanical trigger for toxic tumor therapy
Ultrasound-sensitive nanoparticle aggregates target toxic doses of chemotherapy drugs to tumors while minimizing systemic toxicity
June 15, 2017
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A new magnetic nanoparticle tool to track circulating tumour cells
Cancerous tumours are known to release cells into the bloodstream, and it is these circulating tumour cells (CTC) that are the sources of metastatic tumours -- tumours that spread and form in distant locations in the body and can eventually kill patients.
November 22, 2016
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A new minimally invasive device to treat cancer and other illnesses
A new study by Lyle Hood, assistant professor of mechanical engineering at the University of Texas at San Antonio (UTSA), describes a new device that could revolutionize the delivery of medicine to treat cancer as well as a host of other diseases and ailments (Journal of Biomedical Nanotechnology, "Nanochannel Implants for Minimally-Invasive Insertion and Intratumoral Delivery").
December 1, 2016
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A new role for an old immune cell may lead to novel therapies for infection and cancer
A new study has identified a previously undescribed role for a type of unconventional T cell with the potential to be used in the development of new therapies for infection and cancer.
March 1, 2017
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A Trip to a Roller Coaster Park to Clear Kidney Stones?
While kidney stones are not the cause of death they were in generations past, helping them pass through the urinary tract can still be a challenge and involve a good amount of pain. what if instead the prescribed therapy was a trip to Disney World? Michigan State University urologist David Warninger, a Doctor of Osteopathic Medicine (DO), heard anecdotes of people passing kidney stones while riding a roller coaster, so he set out to investigate the possibility of these claims.
September 23, 2016
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A new way to slow cancer cell growth
Researchers have identified a new way to potentially slow the fast-growing cells that characterize all types of cancer. By removing a specific protein from cells, they were able to slow the cell cycle, which is out of control in cancer. The findings were made in kidney and cervical cancer cells and are a long way from being applied in people, but could be the basis of a treatment option in the future.
May 25, 2017
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Accuray's Radixact Radiotherapy System Cleared in Europe
A month following FDA clearance, Accuray won EU regulatory approval for its Radixact radiotherapy system. the system is an upgrade on the company's TomoTherapy system, with the new device featuring a more powerful accelerator, megavoltage computed tomography (MVCT) imaging, and helical delivery of the radiation.
August 11, 2016
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'Achilles' heel' of key anti-cancer protein
Researchers have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus. the research suggests that the loss of Importin-11 may destabilize PTEN, leading to the development of lung, prostate, and other cancers.
February 13, 2017
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Advancing cancer immunotherapy with computer simulations and data analysis
Supercomputers help researchers classify patients' immune response, design clinical trials and analyze immune repertoire data
May 17, 2017
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Advertising by US cancer centers soars over the past decade, new analysis shows
Cancer centers promoting their services dramatically increased their advertising spending from 2005 to 2014, with the bulk of the spending by for-profit organizations, according to the results of a newly published study.
July 11, 2016
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After Cancer, Higher Risk of Severe Heart Attack
Cardiologists, oncologists must work together, researcher says
December 1, 2016
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Aggressive care in final days of life for advanced cancer patients not linked to better outcomes
For patients with advanced cancer, aggressive care -- chemotherapy, mechanical ventilation, acute hospitalizations and intensive care unit admissions -- at the end of life is commonplace. Yet until now, little is known about the relationship between patients' and families' satisfaction with this aggressive care within the last 30 days of life.
May 25, 2017
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Alternative theory on how aspirin may thwart cancer
Lab studies point to platelet action as key to anti-tumor effect
February 8, 2017
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American Cancer Society awards new $792,000 grant to Yale researcher
The American Cancer Society, the largest non-government, not-for-profit funding source of cancer research in the United States, has approved funding of a new research grant totaling $792,000 to a researcher at Yale University. the grant is among 109 national research and training grants totaling more than $45 million that will fund investigators at 75 institutions across the United States; 102 are new grants while seven are renewals of previous grants. the grants go into effect July 1.
May 4, 2017
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Americans believe cancer to be major health care challenge, Mayo Clinic survey reveals
While Zika remains a hot topic in the news, a new survey by Mayo Clinic reveals that Americans believe the country's most significant health care challenge is cancer. In fact, the survey findings report "infectious diseases, such as Zika and Ebola," are tied with HIV/AIDS as the least important health care challenges listed by respondents following cancer; obesity; neurological diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis; Diabetes and heart disease.
September 14, 2016
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Amino acids in diet could be key to starving cancer
Cutting out certain amino acids -- the building blocks of proteins -- from the diet of mice slows tumor growth and prolongs survival, according to new research.
April 19, 2017
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AMP releases new report that addresses challenges in defining clinical utility of molecular diagnostics
The Association for Molecular Pathology (AMP), the premier global, non-profit organization serving molecular diagnostic professionals, today announced a new report that addresses the challenges in defining the clinical utility of molecular diagnostics for inherited diseases and cancer.
August 17, 2016
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An elegans solution: Worm genetic screen maps cell-to-cell communication in human cancer
A new genetic approach in worms provides a roadmap for the mesenchymal-to-epithelial communication that drives human cancer, report researchers at the Medical University of South Carolina Hollings Cancer Center in Developmental Cell
May 23, 2017
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An engineered protein can disrupt tumor-promoting 'messages' in human cells
A team of researchers have unveiled an engineered protein that they designed to repress a specific cancer-promoting message within cells.
July 21, 2016
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An Innovative new Cancer Therapy Hijacks Bacteria to Fight Tumors
Researchers from South Korea have engineered a strain of bacteria that infiltrates tumors and fools the body™ immune system into attacking cancer cells. In experiments, the modified bacteria worked to reduce cancer in mice, raising hope for human trials.
February 8, 2017
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Animal cancer breakthrough leads to human clinical trials
Cancer treatment in people could be transformed thanks to a study on treating cancer in animals. Injecting oncolytic viruses (viruses that target cancer cells) intravenously into the spleen allows immune responses to be boosted much more rapidly and to much higher magnitudes than traditional vaccine methods.
July 14, 2016
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Annual Report to the Nation: Cancer Death Rates Continue to Decline
Special section on survival finds significant improvement for all but two cancer sites.
March 31, 2017
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Another Study Ties Obesity to Certain Cancers
Digestive organs may be hardest hit by too much weight, study suggests
March 1, 2017
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Anti-PD-L1 immunotherapy responsive in microsatellite-stable mCRC comb with MEK inhibition
Phase I trial achieves partial responses and is well tolerated
June 29, 2016
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Anti-tumor effect of novel plasma medicine caused by lactate
Researchers have developed cold plasma-activated Ringer's solution for chemotherapy. the solution has anti-tumor effects in vitro and in vivo that derive from the lactate component.
December 14, 2016
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Anticancer nanomaterials created by simulating underwater volcanic conditions
Researchers have developed anticancer nanomaterials by simulating the volcano-induced dynamic chemistry of the deep ocean. the novel method enables making nanoclusters of zinc peroxide in an environmentally friendly manner, without the use of additional chemicals. the as-synthesised zinc peroxide nanoparticles can be used as a tool for cancer therapy and against other complicated diseases.
May 12, 2017
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Antipsychotic drug could help reduce nausea and vomiting caused by chemotherapy
Sanford oncologist and cancer researcher Steven Powell, M.D., was among a team of researchers who discovered that the drug olanzapine, which is FDA approved for use as an antipsychotic agent, significantly improved nausea prevention in patients who were receiving chemotherapy for cancer treatment. the drug blocks neurotransmitters involved with nausea and vomiting.
July 20, 2016
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Applying silicon nanoparticles to diagnose and fight cancer
The Lomonosov Moscow State University researchers in collaboration with their German colleagues have succeeded in proving that silicon nanoparticles can be applied to diagnose and cure cancer. for the first time the ability of particles to penetrate into the diseased cells effectively and dissolve completely after delivering the drug was shown
July 20, 2016
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Apricot kernels don't cure cancer, and they might poison you
They contain a compound that's converted into cyanide in the body
August 10, 2016
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Are Cancer Drugs Working? 'Liquid Biopsy' May Tell
But research is still in early stages, experts note
July 13, 2016
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Artificial intelligence uncovers new insight into biophysics of cancer
Machine-learning predicts never-before-seen cancer-like phenotype
January 27, 2017
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ASTRO issues new clinical guideline for management of oropharyngeal cancer with radiation therapy
The American Society for Radiation Oncology today issued a new clinical guideline for the management of oropharyngeal cancer. the guideline, "Radiation therapy for oropharyngeal squamous cell carcinoma: An ASTRO Evidence-based Clinical Practice Guideline," is available as a free access article in Practical Radiation Oncology, ASTRO's clinical practice journal.
April 17, 2017
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At last, a clue to where cancer metastases are born
Scientists have discovered why some cancers may reoccur after years in remission. Importantly, the scientists demonstrated that the escaping tumor cells reach the bloodstream by entering blood vessels deep within the dense tumor core, upending the long-held belief that metastatic cells come from a tumor's invasive borders.
May 2, 2017
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Avoiding over-the-counter heartburn medications could save cancer patients' lives
Medications for heartburn, gastric issues could lower possibility of survival and recovery for cancer patients
December 16, 2016
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Misc. - B

Bacteria as Anti-Cancer Therapy? Interview with Professor Sylvain Martel
Researchers at Universite de Montreal, Polytechnique Montreal, and McGill University have developed a new way to carry anti-cancer drugs to a target site in the body -- using bacteria.
October 28, 2016
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Bacteria used as factories to produce cancer drugs
Researchers at the Novo Nordisk Foundation Center for Biosustainability in Denmark have developed a method of producing P450 enzymes - used by plants to defend against predators and microbes - in bacterial cell factories. The process could facilitate the production of large quantities of the enzymes, which are also involved in the biosynthesis of active ingredients of cancer drugs.
June 2, 2017
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Bacteria used as factories to produce cancer drugs
Researchers have developed a method of producing P450 enzymes -- used by plants to defend against predators and microbes -- in bacterial cell factories. The process could facilitate the production of large quantities of the enzymes, which are also involved in the biosynthesis of active ingredients of cancer drugs.
June 2, 2017
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Bad feelings can motivate cancer patients
Study finds that anger, guilt can inspire positive health habits
April 25, 2017
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Bad luck may play a big role in cancer--but prevention tactics still matter
Study doubles down on earlier work that led to big, some say pointless, controversy.
March 23, 2017
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Barcoding of Nanoparticles to Monitor Effectiveness of Cancer Drugs
Determining which medication is ideal for treating a patient's unique cancer is usually a hit-and-miss affair. a drug is tried and then the tumor monitored for changes. If it works the patient is kept on the same medication, but if it doesn't time is lost and the tumor has only grown.
November 15, 2016
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Better 3D-printed scaffolds help scientists study cancer
Testing treatments for bone cancer tumors may get easier with new enhancements to sophisticated support structures that mimic their biological environment, according to Rice University scientists.
February 8, 2017
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Better scaffolds help scientists study cancer
Design of 3-D printed materials to learn how tumors proliferate
February 8, 2017
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Better understanding of pre-metastatic niches could lead to new preventive therapies
Metastasis is the major cause of cancer-related death and its appearance remains a phenomenon that is difficult to predict and manage. we now know that, prior to the arrival of the cancer cells, tumours prepare the ground in the organ that they will later colonise. These areas with ideal conditions for the onset of metastasis are called pre-metastatic niches and targeting them will help improve patient survival.
March 17, 2017
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Biden Issues Challenge to Speed Cancer Discoveries
Vice President Joe Biden challenged American researchers Wednesday to cram 10 years of work against cancer into 5 years by boosting clinical trials, enlisting big data, and making life-saving drugs cheaper.
June 29, 2016
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Biochemical pathways of kidney disease revealed
Fruit flies used to further our understanding of cysts, cancer
May 2, 2017
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Bioinformatics software developed to predict effect of cancer-associated mutations
Software analyzes 40,000 proteins per minute
June 30, 2016
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Biologists develop new way to inhibit cancer cell cleanup mechanism
The genomes of cancer cells--cells that do not obey signals to stop reproducing--are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins. Like all other cells, cancer cells need to be vigilant about cleaning themselves up in order to survive. Now, biologists in the laboratory of Ray Deshaies, Caltech professor of biology and Howard Hughes Medical Institute Investigator, have developed a new way to inhibit the cancer cell cleanup mechanism, causing the cells to fill up with defective proteins and thus self-destruct.
February 28, 2017
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Biovica appoints Samuel Rotstein as Scientific Advisor
Dr Rotstein received his Ph.D at Karolinska Institutet and has worked as an oncologist for almost 40 years. He was previously Head of Department at the Oncology Clinic at Danderyd Hospital where he together with his colleagues built and managed a highly-appreciated breast cancer clinic. As one of Sweden's leading oncologists, he was honored last year with the Swedish Breast Cancer Patient Advocacy Association's (BRO) Award 2016. Samuel Rotstein is currently working as a physician at Radiumhemmet, Karolinska University Hospital.
May 26, 2017
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Biovica, Eisai sign agreement to analyze DiviTum for improved cancer drug assessment in animal models
Biovica and Eisai Inc. have entered into a lab services agreement to analyze DiviTum™, an assay measuring serum thymidine kinase, for improved drug evaluation in animal cancer models.
October 27, 2016
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Blood vessels and the immune system talk to each other
Implications for cancer treatment
April 3, 2017
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Breakthrough research on radioactive element could lead to new weapon against cancer
A new weapon against cancer could be just around the corner now that a Cal Poly Pomona professor and her colleagues from Stanford, Cornell and Los Alamos National Laboratory have unlocked some of the secrets of a fickle radioactive element.
September 2, 2016
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Brain Training for Cancer Survivors' Nerve Damage
Neurofeedback seems to offers relief from chemo-induced pain, research finds
March 3, 2017
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Bright red fluorescent protein created
After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab. this is good news for researchers, including cancer and stem cell researchers, who use fluorescent proteins to track essential cellular processes.
November 23, 2016
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BUSM scientists map active human apoptosome to provide better understanding of cell death
Programmed cell death, or apoptosis, plays a central role in the maintenance of human health by providing a line of defense against unrestricted cell growth that occurs in many cancers and AIDS as well as in neurodegenerative diseases and stroke.
October 4, 2016
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Misc. - C

Cambridge is giving cancer the 3D VR treatment
It's always good to hear that scientists are bringing the latest technology to the fight against cancer, but virtual reality doesn't seem like an obvious addition to the arsenal. Yet it's VR and 3D visualization that Cambridge University researchers are planning to explore under a multi-million pound grant.
February 10, 2017
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Can big data help cancer patients avoid ER visits?
What if doctors could look into a crystal ball and predict which of their patients might be at risk of getting sick enough to go to the emergency room? for at least one group of patients, that's exactly what researchers are trying to do.
January 30, 2017
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Can childhood cancer treatments affect survivors' sex lives in adulthood?
A recent analysis showed that although adult survivors of childhood cancer did not differ overall from their peers in terms of their satisfaction with their sex lives and romantic relationships, those who received cancer treatments that were especially toxic to the nervous system were least likely to have had intercourse, be in a relationship, or have children.
February 6, 2017
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Cancer bests Zika as top health care concern, national health checkup finds
While Zika remains a hot topic in the news, a new survey reveals that Americans believe the country's most significant health care challenge is cancer. In fact, the survey findings report "infectious diseases, such as Zika and Ebola," are tied with HIV/AIDS as the least important health care challenges listed by respondents following cancer; obesity; neurological diseases, such as Alzheimer's disease and amyotrophic lateral sclerosis; Diabetes and heart disease.
September 13, 2016
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Cancer cells cast a sweet spell on the immune system
Researchers try to wake up immune cells by focusing on the sugars on the tumor surface
March 21, 2017
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Cancer cells grow by exploiting their neighbours
Cancer cells grow by stealing energy from neighboring cells, researchers have discovered.
January 25, 2017
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Cancer cells play hide-and-seek with immune system
When the immune system attacks cancer, the tumor modifies itself to escape the immune reaction, report scientists in a new report.
June 29, 2016
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Cancer cells shown to co-opt DNA 'repair crew'
In experiments with human colon cancer cells and mice, a team led by scientists say they have evidence that cancer arises when a normal part of cells' machinery generally used to repair DNA damage is diverted from its usual task. the findings, if further studies confirm them, could lead to the identification of novel molecular targets for anticancer drugs or tests for cancer recurrence, the investigators say.
May 8, 2017
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Cancer commandeers immature immune cells to aid its successful spread
Cancer commandeers immature immune cells to aid its spread, report scientists. More typically, immature immune cells might help us fight cancer, but scientists have now shown cancer can commandeer the cells to help it spread.
April 7, 2017
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Cancer death rate has dropped 25 percent since 1991 peak
Annual ACS report identifies significant disparities in cancer burden by gender, race
January 5, 2017
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Cancer diagnosis with a breath test
"Inhale deeply ... and exhale.' this is what a test for lung cancer could be like in future. Scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim have developed a method that can detect the disease at an early stage.
April 18, 2017
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Cancer drug could promote regeneration of heart tissue
An anticancer agent in development promotes regeneration of damaged heart muscle -- an unexpected research finding that may help prevent congestive heart failure in the future.
February 3, 2017
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Cancer Experts back CDC's HPV Vaccine Guidelines
Boys and girls should start the shots at age 11 or 12 to prevent cancer-related virus
July 19, 2016
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Cancer in context: 37 years of painstakingly collected data
Latest cancer report card charts trends using data from 1.3 million diagnosed cases in Los Angeles
August 15, 2016
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Cancer in the family: One spouse's diagnosis can lower household income
Caring for a husband or wife with cancer significantly diminishes family income, according to researchers who tracked changes in employment and income among working-age couples in Canada.
April 24, 2017
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Cancer mutation patterns differ in smokers, nonsmokers
DNA damage signatures offer clues to origin of malignancies in various tissues
November 3, 2016
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Cancer now Leading Killer in 12 European Nations
Gains against heart disease and stroke, especially in Western Europe, likely behind the shift
August 15, 2016
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Cancer on a Paleo-diet? Ask someone who lived 1.7 million years ago
Evidence of earliest cancer in homonin record found on South African fossils
July 28, 2016
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Cancer on Course to Become Americans' Top Killer
Report shows it will probably eclipse heart disease as leading cause of death in coming years
August 24, 2016
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Cancer Passes Heart Disease for Leading Cause of Death In These States
For the First Time, 22 States Make the Flip
August 25, 2016
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Cancer patients not getting adequate pain relief
Many terminal cancer patients are not getting adequate pain relief early enough, according to an English study. the researchers found that, on average, terminal cancer patients were given their first dose of a strong opioid such as morphine just nine weeks before their death.
September 15, 2016
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Cancer research: how cells die by ferroptosis
Ferroptosis is a recently discovered form of cell death, which is still only partially understood. Scientists have now identified an enzyme that plays a key role in generating the signal that initiates cell death. Their findings could now give new impetus to research into the fields of cancer, neurodegeneration and other degenerative diseases.
November 15, 2016
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Cancer signaling pathway could illuminate new avenue to therapy
Researchers have better defined a pro-growth signaling pathway common to many cancers that, when blocked, kills cancer cells but leaves healthy cells comparatively unharmed. the study could establish new avenues of therapeutic treatments for many types of solid tumors.
November 23, 2016
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Cancer spread is increased by a high fat diet, ground-breaking evidence shows
Researchers discover new cancer spreading protein
December 6, 2016
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Cancer stem cells in 'robbers cave' may explain poor prognosis for obese patients
A new study offers a compelling hypothesis explaining poor prognosis for obese cancer patients: researchers found that leukemia stem cells "hide" in fatty tissue, even transforming this tissue in ways that support their survival when challenged with chemotherapy.
July 20, 2016
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Cancer therapy may work in unexpected way, study finds
Antibodies to the proteins PD-1 and PD-L1 have been shown to fight cancer by unleashing the body's T cells, a type of immune cell. Now, researchers have shown that the therapy also fights cancer in a completely different way, by prompting immune cells called macrophages to engulf and devour cancer cells.
May 18, 2017
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Cancer therapy: Tracking real-time proton induced radiation chemistry in water
Researchers use laser-based particle acceleration with picosecond time resolution to investigate ultrafast radiation chemistry that occurs immediately after the interaction of protons in water
March 27, 2017
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Cancer Treatment Could be Improved by Imaging Where Nanomedicine Drugs Go in Body
Research has shown that nanomedicine has the potential to minimize the side effects of therapeutic drugs and help customize cancer treatments. There has been some progress with the first goal but not with the second goal of personalizing cancer treatments.
October 27, 2016
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Cancer uses immature immune cells as support system for successful metastasis, study shows
More typically, these immature immune cells might help us fight cancer, but scientists have now shown cancer can commandeer the cells to help it spread.
April 6, 2017
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Cancer-causing benzene found in e-cigarette vapors operated at high power
Significant levels of cancer-causing benzene in e-cigarette vapors can form when the devices are operated at high power, scientists have found.
March 8, 2017
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Cancer-related fatigue: Exercise, psychological therapies best treatments
For patients with cancer-related fatigue, exercise is likely to be last on the list of appealing activities. According to a new study, however, physical activity is the best way to combat this common side effect.
March 3, 2017
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Cancers evade immunotherapy by 'discarding the evidence' of tumor-specific mutations
Discovery could explain widespread acquired resistance among patients treated with immune checkpoint blockade drugs
January 5, 2017
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Cannabinoids and chemotherapy in combination kill cancer cells
A new study confirms that cannabinoids, which are a class of active chemicals in cannabis, can successfully kill leukemia cells. They also find that the combination of chemicals and the order in which they are given is important. The findings will, no doubt, open the door to more effective treatments.
June 7, 2017
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Carbon nanotube based microfluidic chip that captures rare, aggressive cancer cells
In work that could improve understanding of how cancer spreads, a team of engineers and medical researchers at the University of Michigan developed a new kind of microfluidic chip that can capture rare, aggressive cancer cells, grow them on the chip and release single cells on demand.
May 11, 2017
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Cause of tumor resistance to angiogenesis inhibitors identified
The success of specialized drugs to inhibit blood supply to tumors -- so-called angiogenesis inhibitors -- is compromised by the fact that these drugs do not effectively penetrate the tumor tissue and so do not reach the smallest blood vessels in the tumor, a new study has shown for the first time.
January 24, 2017
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Cedars-Sinai Researcher Receives $2.8 Million NIH Grant to Advance Research on Nanomedicine for Cancer Treatment
Julia Ljubimova, MD, PhD, director of the Nanomedicine Research Center in the Cedars-Sinai Department of Neurosurgery, has received a $2.8 million federal grant to advance her research of tumor nanoimmunology to treat cancers of the brain, breast, lung and other organs.
June 30, 2016
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Cell adherence may predict metastasis potential of cancer cells
In metastasis, cancer cells break away from the primary site of the tumor and travel through the blood or lymphatic system to more distant parts of the body. However, only a small number of malignant cells have the ability to form secondary tumors. new research may have found a way to identify these cells.
March 1, 2017
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Cell migration: Cadherin-11 provides the right hold
Cadherins are part of the protein family of adhesion molecules. Just like mortar between the bricks in a wall, they ensure that cells stay together, preventing them from breaking away and migrating from a group of cells. Especially in tumor cells, however, cadherin-11 behaves in exactly the opposite way -- it triggers the migration of cells -- explain researchers.
July 6, 2016
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Cells avoiding suicide may play role in spread of cancer
New studies probe mechanisms of death-defying anastasis
December 9, 2016
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Cells send out stop signs
Signaling molecules can make neuronal extensions retract at a distance
July 6, 2016
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Cellular aging and cancer development: New insight
Medical researchers have discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging. The results of the study will contribute to a better understanding of the human aging process as well as cancer development.
June 14, 2017
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Challenge for some Cancer Survivors: Heart Disease
The younger the age at diagnosis, the greater the risk, study suggests
November 7, 2016
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Changing Cancer Care at Stanford Medicine X
The past weekend we spent at Stanford Medicine X, listening to interesting and inspiring talks, and interacting with a diverse group of people and the ideas they brought with them.
September 19, 2016
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Chemical origami yields new plant compounds with therapeutic and economic potential
Plants produce countless kinds of compounds, also known as natural products, that the plants manufacture using the enzymes predetermined by their genetic code. Many of these natural products are very useful as antibiotics, anti-cancer drugs or vitamins, among myriad other applications. Many of these compounds are far too complex to synthesize in the laboratory, but they can be purified from the plants in which they are found.
November 17, 2016
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Chemistry Technique Concentrates Chemo at Sarcoma Tumor Sites
Today's chemotherapy delivery is poorly targeted, leading to lots of systemic side effects while often doing too little to attack the cancer itself. Researchers at State University of New York at Albany have now developed a way of encapsulating chemo agents within special shells that concentrate and open up around a special pre-positioned material next to a tumor.
July 20, 2016
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Chemists create microscopic environment to study cancer cell growth
According to the American Cancer Society, there will be an estimated 1,688,780 new cancer cases diagnosed and 600,920 cancer deaths in the U.S. in 2017. now a new study may offer new understanding about what turns good cells bad.
March 28, 2017
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Chemists created nanoparticles for safe imaging of tumors
Chemists from Russia and Switzerland created biosafe luminescent nanoparticles for imaging tumors and blood vessels damaged by heart attack or stroke. the particles are made of hafnium oxide that is allowed for intravenous injection, and doped with ions of rare earth metals. the scientists hope that the development will give an alternative to toxic quantum dots and help imaging deep tissues without harming a human body. the study appeared in Colloids and Surfaces B: Biointerfaces.
March 21, 2017
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Chemists develop an ultra-sensitive test for cancers, HIV
Catching a disease in its earliest stages can lead to more effective therapies. Chemists have increased the likelihood of detecting these diseases via a test that is thousands of times more sensitive than current diagnostics.
March 18, 2016
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Chemotherapy drug may increase vulnerability to depression
A chemotherapy drug used to treat brain cancer may increase vulnerability to depression by stopping new brain cells from growing, according to a new study.
April 25, 2017
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Chemotherapy-induced senescent cells promote side effects and cancer relapse
Standard chemotherapy is a blunt force instrument against cancer - and it's a rare cancer patient who escapes debilitating side effects from systemic treatments that mostly affect dividing cells, both malignant and healthy, throughout the body. Researchers at the Buck Institute and elsewhere now show that chemotherapy triggers a pro-inflammatory stress response termed cellular senescence, promoting the adverse effects of chemotherapy as well as cancer relapse and metastasis.
January 17, 2017
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Childhood Cancer Survivors and Later Sexual Health
Study finds especially toxic treatments were tied to later issues, but most rated sex lives as positive
February 6, 2017
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Childhood cancer survivors have poor dietary quality in adulthood, new study finds
Survivors of childhood cancer have poor adherence to federal dietary guidelines in adulthood, a new study finds. Diets lacking essential nutrients may exacerbate the chronic disease burden in a group already at an elevated risk for developing new conditions.
October 19, 2016
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Childhood Cancer Survivors Living Longer
Decline parallels reduced use of radiation, at lower doses, researchers say
February 28, 2017
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Childhood Cancer Survivors Now Living Healthier Lives
Could be due to changes made years ago in treatments children receive, researchers say
June 2, 2017
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China is Racing Ahead of the US in the Quest to Cure Cancer with CRISPR
On Friday, a team of Chinese scientists used the cutting-edge gene-editing technique CRISPR-Cas9 on humans for the second time in history, injecting a cancer patient with modified human genes in hopes of vanquishing the disease.
April 28, 2017
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Cisplatin-based chemotherapy may lead to hearing loss in many testicular cancer survivors
They found that increasing doses of cisplatin were associated with increased hearing loss at most of the tested frequencies, involving 4, 6, 8, 10, and 12 kHz.
June 28, 2016
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Cleaning chromium from drinking water
A novel approach to neutralize a cancer-causing chemical in drinking water has been uncovered by new research. the team has found a new way to convert the dangerous chromium-6 into common chromium-3 in drinking water, making it safer for human consumption.
December 20, 2016
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Clinical trial finds that vitamin D, calcium have no effect on cancer risk
Cancer is the second leading cause of death in the United States and a major public health burden. Previous studies have suggested that vitamin D may lower the risk of developing cancer, so a new randomized trial tests this hypothesis in healthy, older women.
March 28, 2017
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CNIO researchers optimize new system capable of generating cellular model of Ewing sarcoma
A team from the Spanish National Cancer Research Centre (CNIO) has optimized a system capable of generating a cellular model of Ewing sarcoma. the technique, based on CRISPR and described in the pages of Stem Cell Reports, makes it possible to generate cellular models to analyze the mechanisms underlying the origin and progression of this and other diseases, as well as the search for new treatments.
May 10, 2017
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CNS experts create new research-based guidelines for evaluation and treatment of NFPAs
Nonfunctioning pituitary adenomas are common benign tumors that may be present for years before causing any symptoms. a new set of research-based guidelines for evaluation and treatment of NFPAs appears in the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. the journal is published by Wolters Kluwer.
September 23, 2016
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Collabody System for the Delivery of Anticancer Drugs
The Industrial Technology Research Institute, based in Taiwan, has developed the Collabody drug delivery platform, a molecular therapy to enhance and supplement anti-cancer protein drugs. Currently, many anticancer drugs demonstrate poor specificity for cancer cells, meaning that they negatively affect many non-cancerous cells in the body, leading to dose-limitation and off-target effects. the Collabody system enhances the crosslinking activity of anticancer protein drugs with target molecules on the surface of cancer cells, helping to increase protein drug specificity and reduce the interaction of the drug with non-cancerous cells.
November 14, 2016
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Color change test to help cancer research advance
A simple color changing test to help scientists investigate potential cancer drugs has been developed
March 27, 2017
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Combination of anti-angiogenic and immune-stimulating therapies can lead to effective cancer treatments
Scientists from VIB and KU Leuven, together with colleagues from the University of California and the Swiss Institute for Experimental Cancer Research have demonstrated that, anti-angiogenic therapy can improve immune boosting treatments. the successful combination of these two therapies results in the growth of specialized vessels that deliver cancer-fighting immune cells to the tumor, potentially leading to more effective treatments and longer survival periods.
April 13, 2017
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Combination of ginger and chili peppers could help reduce cancer risk
For many people, there's nothing more satisfying than a hot, spicy meal. But some research has suggested that capsaicin, the compound that gives chili peppers their kick, might cause cancer. now researchers show in mouse studies that the pungent compound in ginger, 6-ginergol, could counteract capsaicin's potentially harmful effects.
September 7, 2016
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Combination Therapy for Cancer using Radiation and Nanoencapsulated Drugs
Scientists from the Massachusetts General Hospital (MGH) have discovered an astonishing new role for the immune cells known as macrophages--enhancing the efficaciousness of nanoparticle-delivered cancer treatments.
June 1, 2017
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Combining vitamin C with antibiotics destroys cancer stem cells
A combination of vitamin C and antibiotics could be key to killing cancer stem cells, a new study finds, paving the way for a strategy that could combat cancer recurrence and treatment resistance.
June 13, 2017
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Common class of chemicals cause cancer by breaking down DNA repair mechanisms
A common class of chemicals found everywhere from car exhausts, smoke, building materials and furniture to cosmetics and shampoos could increase cancer risk because of their ability to break down the repair mechanisms that prevent faults in our genes, according to a new study.
June 1, 2017
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Common heart drug repurposed to treat rare cancer in Europe
A drug that's commonly used to treat high blood pressure is being repurposed for a rare tissue cancer in Europe. the medication, named propranolol, was recently granted Orphan Drug Designation by the European Commission (EC).
January 17, 2017
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Common signaling pathway may control formation of tumor cells in fat, reveals Purdue study
A common cell signaling pathway that controls differentiation of stem cells may also control the formation of tumor cells in fat, according to a Purdue University study.
August 31, 2016
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Communication breakdown? Mismatch in expectations about prognosis in advanced cancer
Advanced cancer patients report far more optimistic expectations for survival prognosis than their oncologists, due to patients' misunderstanding of their oncologists' clinical judgment.
July 14, 2016
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Compounds in parsley and dill help fight cancer, research shows
A team of Russian scientists has proposed an efficient approach to novel agents with anticancer activity. a synthesis of these agents is based on compounds extracted from parsley and dill seeds.
June 28, 2016
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Computational research details the activation mechanism of p38?
p38? is a protein involved in chronic inflammatory diseases and cancer, among other pathological conditions. a new study provides a deeper understanding of the structure of this protein, thereby paving the way for the development of more effective inhibitors. These findings are the result of combining fundamental biological data using computational techniques.
April 27, 2017
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Computer program developed to diagnose and locate cancer from a blood sample
Researchers in the United States have developed a computer program that can simultaneously detect cancer and identify where in the body the cancer is located, from a patient's blood sample.
March 24, 2017
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Computer simulation reveals p53 weak spots, opens new avenues against cancer
Using microsecond timescale molecular dynamics simulations, a new study reveals p53 weak spots and sheds light on the protein instability, which is linked to its tendency to aggregate and form amyloid structures.
September 7, 2016
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Computer Vision System Helps Spot Tumor Cells Turning Malignant
Identifying whether a potential drug is having an effect on cancer cells is not always obvious. If enough cells change their morphology, it's fairly easy to see the change under a microscope. Spotting individual cells that are unique among millions of others is what researchers at Brown University have been working on.
October 22, 2016
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Comprehensive review confirms no-calorie sweetener not linked to cancer
In a society where obesity is increasingly recognized as a risk factor for disease, low- and no-calorie ingredients are logical choices for those wishing to manage their weight. However, some people have concerns that sucralose, a no-calorie sweetener, may be linked to cancer.
September 22, 2016
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Connecting the dots between insulin resistance, unhealthy blood vessels and cancer
Animal studies examine risk factors that may overlap between colorectal cancer and cardiovascular disease
May 1, 2017
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Conquering One Big Cancer Side Effect: Fear
Three new therapy programs provide much-needed psychological support, researchers report
June 2, 2017
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'Cooling Caps' May Halt Chemo-Linked Hair Loss
One of two trials was stopped early because results were so strong
February 14, 2017
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Cornell Dots Surprise by Killing Tumor Cells
Cornell dots, or C dots for short, are tiny silica particles that fluoresce under certain conditions. they have shown promise as a way of tagging tumors in preparation for removal, but during safety testing of the C dots a remarkable new ability was discovered. When the peptide-coated C dots were introduced in high doses to tumor cells that were nutrient starved, they seemed to channel iron from the nearby environment into the inside of the tumor cells. this caused the nutrient deprived tumors to die due to their cells' plasma membrane breaking up into multiple pieces.
October 11, 2016
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Could Cancer Have Evolved to be More Common In some Organs Than In Others?
Natural Selection May Have Favored Stronger Anti-Cancer Protection for Critical Organs
August 09, 2016
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Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan
Can you please outline your latest research where you triggered the apoptosis 'switch' on in cancer cells forcing them to commit 'suicide'?
August 15, 2016
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Counterintuitive approach to treating a brain cancer
The loss of the tumor suppressor gene PTEN has been linked to tumor growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM). Now, researchers have shown that one way to override the growth-promoting effects of PTEN deletion is, surprisingly, to inhibit a separate tumor suppressor gene.
May 12, 2017
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CRISPR/Cas9 technology to inactivate cancer mutations
As for many other biomedical and biotechnology disciplines, the genome scissor "CRISPR/Cas9" also opens up completely new possibilities for cancer research. Scientists of the National Center for Tumor Disease (NCT), the German Consortium for Translational Cancer Research (DKTK) and the Medical Faculty of the TU Dresden have shown that mutations that act as cancer drivers can be targeted and repaired.
August 31, 2016
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Crossing the barriers: Pharmacy researchers improving drug delivery
Developing nanosystems that can more easily cross the gastrointestinal tract and blood-brain barriers
July 14, 2016
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Crowd-sourced competition to create 'big data' diagnostic tools
A crowdsourced collaboration/competition known as DREAM 9 set out three years ago to develop ideas for computational tools that would help treat patients with acute myeloid leukemia.
June 29, 2016
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Cutting down on cancer surgeries
New microscopy technique could reduce repeat surgeries for breast cancer patients
May 17, 2017
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Misc. - D

Danish research may pave way for immunological treatment of cancer
Researchers from Aarhus University have found an important piece of the puzzle leading towards an understanding of how our innate immune system reacts against viral infections and recognises foreign DNA, for example from dying cancer cells. the discovery may prove to be of great importance for immunological treatment of cancer as well as autoimmune diseases in the future.
February 21, 2017
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Dartmouth study examines impact of health insurance status on cancer care
Millions of Americans acquire their health insurance under the Affordable Care Act, including individuals from disadvantaged communities (as defined by a summary measure comprised of U.S. Census measures of income, education, and employment). Patients with one of the four leading causes of cancer deaths have lower rates of cancer-specific survival based on where they live, specifically based on their social determinants of health.
January 27, 2017
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DCIS patients more likely to be alive ten years later than women in general population
Women over 50 who have been treated for ductal carcinoma in situ (DCIS) are more likely to be alive ten years later than women in the general population, according to new research presented at the European Cancer Congress 2017.
January 27, 2017
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Deadly nanoparcel for cancer cells
Most tumors contain regions of low oxygen concentration where cancer therapies based on the action of reactive oxygen species are ineffective. Now, American scientists have developed a hybrid nanomaterial that releases a free-radical-generating prodrug inside tumor cells upon thermal activation.
May 4, 2017
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Deadly nanoparcel for cancer cells
Free-radical-generating hybrid nanomaterial for the oxidative destruction of hypoxic cancer cells
May 4, 2017
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Decisions in a pinch: Receptor tyrosine kinases control mechanosensors
The role of receptor tyrosine kinases in the regulation of the cellular mechanosensory machinery is now better understood, this discovery has relevance for understanding the basis of cancerous growth and developmental abnormalities.
September 21, 2016
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Deep Learning Algorithms Applied to Tracking Tumor Development
Researchers from the Fraunhofer Institute for Medical Image Computing, Germany willl soon be showing off a new deep learning software that is able to measure the size of tumors undergoing treatment and detect new metastases that may otherwise be overlooked.
November 7, 2016
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Deep Learning, AI Could One day Assist in Spotting Cancer
Deep learning and artificial intelligence are on their way to bringing about a sea change in how we use computers in medicine. Neural networks have the power to work toward solutions using approaches they devise on their own -- and it gives them incredible problem-solving capabilities.
May 12, 2017
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Deficiency in NMD could cause inflammatory myofibroblastic tumors
Inflammatory myofibroblastic tumors (IMTs) – masses of immune cells– are benign, but poorly understood. Current IMT treatments often have side effects and surgery is sometimes not an option due to the tumor's proximity to vital organs. a better understanding of how IMTs form could spur the development of more effective therapeutics. Researchers at University of California San Diego School of Medicine have now found that a likely cause of IMT is deficiency in nonsense-mediated RNA decay (NMD), a system cells use to control which genes are activated.
June 28, 2016
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Delirium underdiagnosed in advanced cancer patients visiting emergency department
A new study indicates that delirium is relatively frequent and underdiagnosed by physicians in patients with advanced cancer visiting the emergency department. Delirium was similarly common among older and younger patients, which suggests that in the setting of advanced cancer, all patients should be considered at higher risk for delirium.
July 25, 2016
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Deploying an ancient defense to kill cancer
What if your body's ancient defenses against invading bacteria could be hijacked to help kill cancer? In a small sarcoma trial, scientists have found signs of immune attack after injections of a bacteria-inspired drug.
April 3, 2017
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Designer Virus Tells the Immune System How to Fight Cancer
A virus can cause illness and even death if you become infected with the wrong one. However, a virus has no malicious intentions; it's simply a bundle of genetic code programmed to make copies of itself. Researchers have been exploring ways to hijack the functionality of a virus to deliver new beneficial genes to cells.
June 1, 2017
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Designer Viruses Help Fight Cancer
Scientists have created artificial viruses for use in eliminating cancer cells.
May 31, 2017
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Designer viruses stimulate the immune system to fight cancer
Swiss scientists have created artificial viruses that can be used to target cancer. These designer viruses alert the immune system and cause it to send killer cells to help fight the tumor. The results, published in the journal Nature Communications ("Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy"), provide a basis for innovative cancer treatments.
May 26, 2017
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Designing ultrasound protein tools with molecular engineering
Ultrasound imaging is used around the world to help visualize developing babies and diagnose disease. Sound waves bounce off the tissues, revealing their different densities and shapes. the next step in ultrasound technology is to image not just anatomy, but specific cells and molecules deeper in the body, such as those associated with tumors or bacteria in our gut.
August 25, 2016
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Detailed structure of cell's garbage disposal unit reveals surprise in how it is targeted by cancer drugs
Every atom counts
August 04, 2016
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Detection system reads biomolecules in barcoded microgels
Single-stranded, noncoding micro-ribonucleic acids (microRNAs), consisting of 18-23 nucleotides, play a key role in regulating gene expression. Levels of microRNAs circulating within blood can be correlated to different states of diseases such as cancer, neurodegenerative disorders and cardiovascular conditions. Many microRNAs within the blood are encapsulated within exosomes, nanoscale vesicles released by the cells.
December 19, 2016
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Diarrhea-causing Salmonella can be weaponized to flush out cancer
In mice, armed bacteria infiltrated human tumors and triggered destruction.
February 9, 2017
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Differences found in cancer occurrence within African and US born blacks
The cancer profile of African-born blacks differs from that of United States-born blacks and varies by region of birth, according to a new study. the study, appearing in CANCER, suggests differences in environmental, cultural, social, and genetic factors, and points to an opportunity to study the risk factors associated with the cancer burden in African-born blacks to help create targeted interventions.
April 14, 2017
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DNA 'barcoding' allows rapid testing of nanoparticles for therapeutic delivery
Using tiny snippets of DNA as 'barcodes,' researchers have developed a new technique for rapidly screening the ability of nanoparticles to selectively deliver therapeutic genes to specific organs of the body. the technique could accelerate the development and use of gene therapies for such killers as heart disease, cancer and Parkinson's disease.
February 7, 2017
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DNA Ferrying Nanoparticles Turbocharge Cancer Immunotherapy
At the National Institute of Biomedical Imaging and Bioengineering, a part of the National Institutes of Health, scientists have developed a "nanovaccine" for safer delivery of immunotherapies. DNA strings need to be carefully introduced near the target in order to activate the immune system to kill nearby cancer cells, but enzymes easily break them up if the delivery is poorly focused.
August 25, 2016
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DNA patterns can unlock how glucose metabolism drives cancer, study finds
Less aggressive cancers are known to have an intact genome--the complete set of genes in a cell--while the genome of more aggressive cancers tends to have a great deal of abnormalities. Now, a new multi-year study of DNA patterns in tumor cells suggests that these aberrant genetic signatures are not random but reflect selective forces in tumor evolution.
February 15, 2017
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Do mobile phones cause cancer? Evidence still says 'no' despite what random people on an Italian jury think
Can we please stop having this debate?
April 21, 2017
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Doctors can now prescribe Jabra fitness headphones to treat obesity, cancer and diabetes
Jabra has teamed up with the TrainerMD health program to help doctors monitor patients' health stats in real time using the company's new Sport Pulse Special Edition fitness earbuds.
August 19, 2016
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Doctors don't have to see cancer to suspect it's there
Global processing lets radiologists pick up on cancerous tissue in a half-second.
September 7, 2016
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Dual loss of TET proteins prompts lethal upsurge in inflammatory T cells in a mouse model of lymphoid cancer
Members of the TET family of proteins help protect against cancer by regulating the chemical state of DNA --and thus turning growth-promoting genes on or off. These latest findings illustrate just how important TET proteins are in controlling cell proliferation and cell fate.
December 12, 2016
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Dual-action cancer nanomedicine therapy
A French-Australian research team has fabricated antibody-coated porous silicon nanoparticles that can actively target cells through binding to specific cell-surface receptors. They demonstrated that these nanoparticles can bind to and selectively deliver multiple therapeutics to human B cells in vitro.
June 6, 2017
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Dual-targeting nanoparticles lower cancer's defenses and attack tumors
Cancer immunotherapy has emerged as one of the most exciting directions in cancer treatment. But the approach only works in a fraction of patients and can cause nasty side effects.
June 7, 2017
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Dying tumor cells release intracellular ions in a last-ditch attempt to block the immune system
Researchers have discovered how a mineral ion leaked from tumor tissue as it dies acts to stop the work of anti-tumor immune cells. this discovery provides a new approach in the development of treatments to engage the immune system in the fight against cancer.
September 15, 2016
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Misc. - E

Early death from pediatric cancer subtypes more likely to happen than previously reported
Treatments for childhood cancers have improved to the point that 5-year survival rates are over 80 percent. However, one group has failed to benefit from these improvements, namely children who die so soon after diagnosis that they are not able to receive treatment, or who receive treatment so late in the course of their disease that it is destined to fail.
March 8, 2017
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Early deaths from childhood cancer up to 4 times more common than previously reported
Treatments for childhood cancers have improved to the point that 5-year survival rates are over 80 percent. However, one group has failed to benefit from these improvements, namely children who die so soon after diagnosis that they are not able to receive treatment, or who receive treatment so late in the course of their disease that it is destined to fail.
March 8, 2017
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Economic crisis linked to cancer mortality increase? An interview with Dr Mahiben Maruthappu
How did the number of cancer deaths change following the 2008 global economic crisis?
August 09, 2016
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Editing preferences of enzymes may play role in infertility and cancer
To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. Now, new research shows how an enzyme called KDM4B "reads" one and "erases" another so-called epigenetic mark on a single histone protein during the generation of sex cells in mice. the researchers say the finding may one day shed light on some cases of infertility and cancer.
November 28, 2016
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EFSA decision upholds years of research that shows safety of sucralose
The European Food Safety Authority (EFSA) decision upholds years of research on sucralose - the sweetening ingredient in the original SPLENDA Sweeteners - that shows it to be safe and does not cause cancer. the decision was published as an open access Scientific Opinion in EFSA Journal, and rejects allegations made by a small Italian lab regarding a study in mice that they conducted. EFSA concluded that "the available data did not support the conclusions of the authors (Soffritti et al., 2016)."
May 8, 2017
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Encouraging results from combination therapy in Hodgkin lymphoma
Combination therapy with brentuximab vedotin and gemcitabine in patients is "highly active" regimen for patients with Hodgkin lymphoma, the authors of a phase II clinical study report.
June 6, 2017
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Enhanced CRISPR lets scientists explore all steps of health and disease in every cell type
Researchers from the Wellcome Trust Sanger Institute and the University of Cambridge have created sOPTiKO, a more efficient and enhanced inducible CRISPR genome editing platform. In the journal Development, they describe how the freely available single-step system works in every cell in the body and at every stage of development. this new approach will aid researchers in developmental biology, tissue regeneration and cancer.
December 1, 2016
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Enzyme's 'editing' preferences have implications for infertility, cancer
To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. Now, new research shows how an enzyme called KDM4B "reads" one and "erases" another so-called epigenetic mark on a single histone protein during the generation of sex cells in mice. the researchers say the finding may one day shed light on some cases of infertility and cancer.
November 28, 2016
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Epigenetic change ties mitochondrial dysfunction to tumor progression
Scientists have identified a mechanism by which mitochondria can drive changes in nuclear gene expression that are associated with tumor progression.
December 21, 2016
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Equashield Pro Automated High-Throughput Compounding Robot for Chemo Drugs
Equashield, a Port Washington, NY firm, will be unveiling their first automated compounding robot. Technically called Closed System Transfer Devices (CSTD), such devices essentially reproduce a needle and a syringe action to compound drugs, particularly chemo agents for IV administration. Because such drugs can be toxic to clinical staff, the Equashield Pro has a number of proprietary safety systems and design elements that prevent exposure and cross-contamination.
November 28, 2016
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ESMO announces takeover of Targeted Anticancer Therapies Congress series
ESMO, the leading European organisation for medical oncology, has announced it will take over the organisation of the Targeted Anticancer Therapies (TAT) Congress series, with the aim of expanding its educational offer and ensure that professionals are kept up to date with the latest drug developments to improve outcomes for cancer patients.
March 7, 2017
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Everolimus R-CHOP combination safe for treating diffuse large B-cell lymphoma
The targeted therapy everolimus may be safely combined with R-CHOP for new, untreated diffuse large B-cell lymphoma according to the results of a pilot study. R-CHOP is a combination of drugs used to treat lymphoma. the combination includes rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone.
June 29, 2016
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Examining cost-effectiveness of initial diagnostic exams for microscopic hematuria
Routine urinalysis for screening of genitourinary cancer isn't recommended by any major health group but patients who undergo urinalysis for a variety of other reasons are often found to have microscopic hematuria, which prompts further evaluation. a new article explores the cost-effectiveness of four initial diagnostic protocols for these patients.
April 17, 2017
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Exercise Good During, After Cancer Treatment
Studies show better physical function, quality of life for those who did strength training, aerobic activity
November 15, 2016
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Exercise Helps Counter Cancer-Linked Fatigue
Psychological treatment and education can be useful, too, more so than drugs, study finds
March 2, 2017
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Expanded role of PARP proteins opens the door to explore therapeutic targets in cancer
Using technology they developed, researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.
August 15, 2016
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Experimental cancer drug shows promise
New study suggests GGTI-2418 can block one specific protein from binding to and degrading another protein known for killing cancer cells.
June 14, 2017
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Expert panel to Washington: Here's how we cure cancer
A panel of cancer experts has released its list of recommendations for the government's big Cancer Moonshot program, a bid to bring the success of the Silicon Valley model to bear on cancer, the emperor of all maladies. it's an intriguing list, spanning the very general to the very specific. It includes guidelines for how to improve everything from basic molecular biology to compassionate patient outreach.
September 13, 2016
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Experts call for expansion of molecular imaging in precision cancer care
The noninvasive approach needs more research but carries added benefits to biopsies, they say
December 29, 2016
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Explainer: what is nanomedicine and how can it improve childhood cancer treatment?
A recent US study of people treated for cancer as children from the 1970s to 1999 showed that although survival rates have improved over the years, the quality of life for survivors is low. It also showed this was worse for those who were treated in the 1990s.
May 24, 2017
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Exposure to carcinogenic compounds can come with inhalation of vaporized cannabis oil, study shows
New research shows that the agents commonly mixed with cannabis oil for vaping can also produce cancer-causing compounds when heated. The effect is similar to the potential health risks linked to cigarette smoke and agents used in e-cigarettes. The new study demonstrates that exposure to harmful levels of formaldehyde can come with a single inhalation of vaporized cannabis oil.
June 12, 2017
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Exposure to community violence linked to violent behavior among minority adolescent men
As exposure to community violence increases for adolescent men of color, symptoms of depression subside and violent behaviors increase, according to new research published in the Journal of Clinical Child & Adolescent Psychology, a journal of the Society of Clinical Child and Adolescent Psychology. the results add evidence to a model demonstrating the desensitization to violence that can occur with greater exposure.
October 5, 2016
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Exposure to medical imaging radiation does not increase child's cancer risk
In an article published in the June 2017 issue of The Journal of Nuclear Medicine, researchers assert that exposure to medical imaging radiation not only doesn't increase an adult person's risk of getting cancer, it doesn't increase a child's risk. According to the authors, the long-held belief that even low doses of radiation, such as those received in diagnostic imaging, increase cancer risk is based on an inaccurate, 70-year-old hypothesis and leads to unnecessary fear and misdiagnoses.
June 7, 2017
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Extensive use of fluorinated chemicals in fast food wrappers: Chemicals can leach into food
Previous studies have linked the chemicals to kidney and testicular cancers, thyroid disease, low birth weight and immunotoxicity in children, among other health issues.
February 1, 2017
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Extreme short and long telomeres linked to increased cancer risk
The length of the telomere "caps" of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics, University of Pittsburgh Cancer Institute scientists will report today at the AACR Annual Meeting in Washington, D.C.
April 3, 2017
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Misc. - F

Fake Breast Cancer Charity Must Shut Down, Pay $350K To Real Charities
A purported charity called The Breast Cancer Survivors Foundation existed for six years, raising money through direct mailers and soliciting donors over the phone. It took in about $3 million per year, spinning heartwarming tales in its mailings of helping patients. This turned out to not actually be true, and those millions went to the professional fundraiser who ran the operation.
June 16, 2017
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Fast capture of cancer markers will aid in diagnosis, treatment
A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis. Researchers have developed nanoprobes to rapidly isolate these rare markers, called extracellular vesicles (EVs), for potential development of precision cancer diagnoses and personalized anticancer treatments.
April 10, 2017
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Faster biosensor for healthcare now developed
A new technology has been designed that is 20 times faster than the existing biosensors using micromagnetic pattern of spider web. the technology can be used for early diagnosis and recurrence diagnosis of diseases such as cancer.
April 21, 2017
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Fateful evolution: new study improves accuracy of cancer diagnosis
Researchers use evolutionary theory to make predictions about which Barrett's esophagus (BE) patients will go on to develop cancer. the results point the way toward more accurate medical assessments for patients with BE and the development of early-warning beacons of disease known as biomarkers.
August 25, 2016
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FDA Approves Drug for Duchenne Muscular Dystrophy
A new drug to treat Duchenne muscular dystrophy has been approved by the U.S. Food and Drug Administration.
February 10, 2017
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FDA approves new therapy for initial treatment of soft tissue sarcoma
The U.S. Food and Drug Administration today granted accelerated approval to Lartruvo (olaratumab) with doxorubicin to treat adults with certain types of soft tissue sarcoma (STS), which are cancers that develop in muscles, fat, tendons or other soft tissues. Lartruvo is approved for use with the FDA-approved chemotherapy drug doxorubicin for the treatment of patients with STS who cannot be cured with radiation or surgery and who have a type of STS for which an anthracycline (chemotherapy) is an appropriate treatment.
October 19, 2016
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FDA approves scalpel-free brain surgery to treat essential tremor
The Food and Drug Administration has approved the first focused ultrasound device to treat essential tremor, the most common movement disorder, in patients who do not respond to medication. the scalpel-free approach has been pioneered by Jeff Elias, MD, at the University of Virginia School of Medicine, who led an international clinical trial that demonstrated the safety and effectiveness of the device.
July 21, 2016
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FDA grants Orphan Drug Designation to CD4CAR therapy for treatment of peripheral T-cell lymphoma
iCell Gene Therapeutics today announced that the Food and Drug Administration has granted Orphan Drug Designation for its chimeric antigen receptor engineered T-cells directed against the target protein CD4 (CD4CAR) for the treatment of peripheral T-cell lymphoma (PTCL).
August 12, 2016
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FDA OKs First Cancer Drug by Genetic Type, Not Organ of Origin
Keytruda is targeted to specific cancers with specific DNA that can arise in multiple sites
May 24, 2017
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FDG PET-CT imaging helps assess anatomical structure and metabolic activity in patients with GLILD
A new proof of concept study has shown that an imaging technique more commonly used to assess cancer patients may also be of help in assessing disease and treatment effects in patients with inflammatory diseases.
November 30, 2016
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Fetal genomic sequencing could enhance detection rate of genetic findings, study shows
In a study to be presented Thursday, Jan. 26, in the oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, the Pregnancy Meeting™, researchers with the Columbia University Medical Center in New York found that, in preliminary data, fetal genomic (whole exome) sequencing (WES) as a diagnostic test for women with pregnancies complicated by major fetal congenital anomalies increased the detection rate of genetic findings by between 10 to 30 percent.
January 23, 2017
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Fighting cancer with immunotherapy: Signaling molecule causes regression of blood vessels
Immunotherapy with T-cells offers great hope to people suffering from cancer. some initial successes have already been made in treating blood cancer, but treating solid tumors remains a major challenge. the signaling molecule interferon gamma, which is produced by T-cells, plays a key role in the therapy. It cuts off the blood supply to tumors, as a new study reveals.
April 26, 2017
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Fighting cancer with space research
JPL and National Cancer Institute renew big data partnership
September 15, 2016
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Fighting cancer with sticky nanoparticles
Sticky nanoparticles that deliver drugs precisely to their targets – and then stay there – could play a crucial role in fighting ovarian and uterine cancers.
September 20, 2016
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Finding Pain Relief Tough Even at Cancer Centers
'Mystery shopper' study shows staff at 1 in 10 facilities gave people misinformation on palliative care services
September 20, 2016
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First 3D map of cell-building protein linked to cancer
Researchers have revealed, for the first time, the three-dimensional molecular 'map' of a protein that has been pinpointed as a driver of many types of cancers.
August 19, 2016
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First dual-targeting nanoparticles lower cancer's defenses and attack tumors
Cancer immunotherapy has emerged as one of the most exciting directions in cancer treatment. But the approach only works in a fraction of patients and can cause nasty side effects. Now scientists report the development of the first dual-cell targeting immunotherapy nanoparticle that slows tumor growth in mice with different cancers. In their study, up to half the mice in one cancer group went into full remission after the treatment.
June 7, 2017
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First multicellular organism inspires the design of better cancer drugs
The first multicellular organism, Volvox, evolved from self-assembly of individual cells. Inspired by this organism, researchers from Brigham and Women's Hospital have developed a novel approach for treating cancer. Drawing from the lessons of evolution, they designed anti-cancer molecules that can self-assemble with each other into a complex structure through weak supramolecular interactions. the complex, supramolecular therapeutics home into the tumor, increasing anticancer efficacy and reducing side effects.
September 12, 2016
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First 'nanotherapeutics' delivered to a tumor
Technique targets disease, spares nearby tissues
May 15, 2017
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First use of graphene to detect cancer cells
By interfacing brain cells onto graphene, researchers have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early cancer diagnosis.
December 19, 2016
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First use of graphene to detect cancer cells
By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early cancer diagnosis.
December 19, 2016
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Five Major Cancer Studies Are Proving Difficult to Reproduce
Humanity would understand very little about cancer, and be hard-pressed to find cures, without scientific research. But what if, when teams recreated each other's research, they didn't arrive at the same result?
January 19, 2017
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Food withdrawal results in stabilization of important tumor suppressor
Tumor suppressors stop healthy cells from becoming cancerous. Researchers have found that p53, one of the most important tumor suppressors, accumulates in liver after food withdrawal.
December 21, 2016
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Functional brain training alleviates chemotherapy-induced peripheral nerve damage in cancer survivor
Neurofeedback also results in measureable changes in targeted brain activity
March 3, 2017
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Misc. - G

Gasotransmitters in the body could potentially be used to develop new drugs
Gases once thought of only as environmental pollutants are now known to be produced by the body. they could potentially be used to develop drugs to treat diseases including heart failure and cancer.
August 08, 2016
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Gastrointestinal cancer: Physical exercise helps during chemo
Walking or jogging helps patients with advanced gastrointestinal cancer to cope better with the side effects of chemotherapy, shows new research.
March 10, 2017
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Gene editing technique helps find cancer's weak spots
Genetic mutations that cause cancer also weaken cancer cells, allowing researchers to develop drugs that will selectively kill them. this is called "synthetic lethality" because the drug is only lethal to mutated (synthetic) cells. Researchers have developed a method to search for synthetic-lethal gene combinations. the technique uncovered 120 new opportunities for cancer drug development.
March 19, 2017
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Gene therapy technique may help prevent cancer metastasis
Gene-regulating RNA molecules could help treat early-stage breast cancer tumors before they spread
September 21, 2016
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Genetic analysis better explains how uterine cancers resist treatment
Researchers have charted the complex molecular biology of uterine carcinosarcoma, a rare and aggressive gynecologic cancer, according to a new study.
March 13, 2017
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Genetic biomarker IDs patients with increased risk for heart damage by anthracycline chemo
Among women with breast cancer who received a type of chemotherapy called an anthracycline, those who had a certain genetic biomarker had a significantly increased risk for having anthracycline-induced congestive heart failure.
December 19, 2016
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Genetic control of immune cell proliferation
Germinal centers are transient structures in the lymph nodes where antibody-producing B cells proliferate and differentiate at extraordinary rates. Germinal centers can be visually divided into a dark zone and light zone. for the proliferation and differentiation to occur, B cells must cycle between the two zones. Investigators have discovered how specific genes regulate this cycling. the findings provide new insights on how certain types of lymphomas form.
April 19, 2017
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Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior
Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report.
December 2, 2016
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Generic Gleevec will Likely Save Millions in Costs
Over 5 years, researchers estimate more than $9 million in insurance savings
March 18, 2016
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Genetic profiling increases cancer treatment options, study finds
GEMMA clinical trial identified treatment options through personalized medicine
July 27, 2016
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Genetic profiling of blood cells can predict response to stem cell transplant for patients with MDS
A single blood test and basic information about a patient's medical status can indicate which patients with myelodysplastic syndrome (MDS) are likely to benefit from a stem cell transplant, and the intensity of pre-transplant chemotherapy and/or radiation therapy that is likely to produce the best results, according to new research by scientists at Dana-Farber Cancer Institute and Brigham and Women's Hospital.
February 9, 2017
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Genetic risk of getting second cancer tallied for pediatric survivors
Faulty genes, not just treatment side effects, to blame for double whammy
April 7, 2017
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Genetic screening and counseling likely to benefit childhood cancer survivors, study suggests
Twelve percent of childhood cancer survivors carry germline mutations that put them or their children at increased risk of developing cancer, according to a landmark study presented today at the annual meeting of the American Association for Cancer Research. the findings from St. Jude Children's Research Hospital are expected to have an immediate and potentially life-saving impact on the growing population of childhood cancer survivors.
April 4, 2017
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Genetic sequencing could influence treatment for nearly three-quarters of advanced cancer patients
More biomarker-based clinical trials will increase opportunities
June 2, 2017
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Genome editing 'toolbox' targets multiple genes at once
Scientists have designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects. the gene-editing 'toolbox' provides a user-friendly solution that scientists can apply to research on cancer and other disciplines, the researchers said.
July 26, 2016
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Genome sequencing approach opens door to therapy options for rare, neglected cancers
An international team of scientists led by the Icahn School of Medicine at Mount Sinai and UConn School of Medicine have reported the results of a genome sequencing study for an extremely rare form of cancer. Their findings demonstrate the utility of this approach to open the door for therapy options for rare diseases that are neglected due to scarcity of patients or lack of resources.
March 23, 2017
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Gentle cancer treatment using nanoparticles works
Cancer treatments based on laser irridation of tiny nanoparticles that are injected directly into the cancer tumor are working and can destroy the cancer from within. Researchers have developed a method that kills cancer cells using nanoparticles and lasers.
August 03, 2016
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Gentle cancer treatment using nanoparticles works
Cancer treatments based on laser irridation of tiny nanoparticles that are injected directly into the cancer tumor are working and can destroy the cancer from within. Researchers from the Niels Bohr Institute and the Faculty of Health Sciences at the University of Copenhagen have developed a method that kills cancer cells using nanoparticles and lasers.
August 03, 2016
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Ginseng nanoparticles for cancer treatment
A recent editorial in Nanomedicine by scientists in Korea states that use of ginsenoside nanoconjugates could be a promising candidate against cancer and various other diseases, such as inflammation, osteoporosis and obesity in the future.
May 19, 2017
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Globe-trotting pollutants raise some cancer risks four times higher than predicted
A new way of looking at how pollutants ride through the atmosphere has quadrupled the estimate of global lung cancer risk from a pollutant caused by combustion, to a level that is now double the allowable limit recommended by the World Health Organization.
January 26, 2017
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Gold and Lasers Produce Plasmonic Nanobubbles to Kill Residual Cancer Cells
Plasmonic nanobubbles intraoperatively detect microscopic residual disease in a surgical bed and guide its resection in real time with standard surgery
July 13, 2016
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Gold nanoparticle cancer therapy reduces toxic chemotherapy effects
Virginia Tech scientists have developed a new cancer drug that uses gold nanoparticles created by the biotech firm CytImmune Sciences to deliver paclitaxel – a commonly used chemotherapy drug directly to a tumor.
November 14, 2016
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Good indicator of cancer prognosis turned on its head by new research
A molecule which, for the last 20 years has been believed to be an indicator of good prognosis in tumors, has been shown to have a dark side, scientists report.
July 7, 2016
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Good news for cyclists: you might live longer
A recent study published in the BMJ finds that cycling or walking to work reduces the risk of death from all causes, when compared with non-active commuting. the biggest effect was seen in cyclists, so it might be time to get your bike back out of the garage.
April 24, 2017
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Google DeepMind wants to use machine learning to help treat certain cancers
Google DeepMind is launching a project to reduce the time it takes doctors to prepare treatment for head and neck cancers. Alphabet's London-based artificial intelligence division has partnered with the UK's National Health Service and will be conducting the research in coordination with the University College London Hospital.
August 30, 2016
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Grail is raising at least $1 billion to fund its early cancer screening test
The early cancer screening startup Grail plans to raise more than $1 billion in Series B financing, possibly up to $1.8 billion.
January 5, 2017
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Graft-versus-host disease successfully prevented
Regimen may stop common side effect of stem cell transplants for hematologic cancer patients, report suggests
April 18, 2017
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Griffith scientists discover new and improved tool to detect cancer
Studying the food poisoning bacteria E. coli may have led scientists to discover a new and improved tool to detect cancer.
June 8, 2017
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Groundbreaking discovery has potential to improve therapies for cancer and other diseases
Study changes understanding of the Retinoblastoma protein and its role as a tumor suppressor
December 14, 2016
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Groups of Nanoparticles Powered by a Magnet Team Up to Kill Cancer Cells
Number of ways have been developed that allow nanoparticles to kill cancer cells. Some of these include delivering chemo agents, converting electromagnetic energy beamed into heat, and manipulating with the signaling processes of tumor cells.
June 14, 2017
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Gut bacteria could protect cancer patients and pregnant women from Listeria
Researchers have discovered that bacteria living in the gut provide a first line of defense against severe Listeria infections. The study suggests that providing these bacteria in the form of probiotics could protect individuals who are particularly susceptible to Listeria, including pregnant women and cancer patients undergoing chemotherapy.
June 6, 2017
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Guy's Cancer Centre adds new positioning equipment to enhance patient comfort during radiotherapy treatment
A range of breast, head and neck boards aid a comfortable and welcoming patient experience at one of the UK's leading cancer centres
February 1, 2017
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Misc. - H

Having an extra chromosome has a surprising effect on cancer
Smaller tumors, less cancer-driving proteins seen with trisomic cells
December 6, 2016
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Heart problems from common cancer treatment can be alleviated by using gene therapy
Researchers of the Wihuri Research Institute and the University of Helsinki, Finland, have found that some of the harmful effects of a commonly used cancer drug can be alleviated by using gene therapy that stimulates blood vessel growth in the heart.
October 30, 2016
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Helpful tool allows physicians to more accurately predict parathyroid cancer recurrence
A newly-created prognostic tool reliably predicts the recurrence of parathyroid cancer, enabling physicians to identify patients at the highest risk. Consequently, the tool also helps to determine the optimum postoperative strategy, including aggressive surveillance and additional treatments, according to study results.
April 28, 2017
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HCI researchers uncover how epithelial cells naturally turn over to maintain constant numbers
Epithelial cells comprise the skin and skin-like linings that coat internal organs, giving organs a protective barrier so they can function properly. Cells turn over very quickly in epithelia. to maintain healthy cell densities, an equal number of cells must divide and die. If that balance gets thrown off, inflammatory diseases or cancers can arise.
February 15, 2017
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High Doses of Vitamin D Fail to Cut Cancer Risk
Taking triple the daily recommendation didn't lower risk in older women, but larger trials are underway
March 28, 2017
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High Rate of Antidepressant Use After Cancer
Nearly 1 in 5 survivors taking medication for depression or anxiety years later
October 27, 2016
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High-Capacity Nanoparticle for Potential Use in Targeted Cancer Therapy
Nanoparticles provide a promising way to deliver cancer drugs in a targeted manner, which help to kill the cancer cells without affecting the healthy tissue. the downside is that a most of the nanoparticles previously developed are only capable of carrying one or two drugs.
September 16, 2016
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High-dose vitamin C makes cancer treatment more effective, trial shows
Common treatment options for cancer, such as chemotherapy and radiation therapy, can be expensive and sometimes ineffective. However, a new clinical trial tests the effect of high-dose vitamin C in combination with standard treatment on health outcomes for patients with cancer.
March 31, 2017
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Higher Odds for Certain Cancers for Couch Potatoes
Researchers say get moving, and point to national exercise guidelines
June 15, 2017
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Higher vitamin D levels linked to lower cancer risk, study suggests
Increasing vitamin D levels may lower risk for developing cancer, according to a study conducted by Creighton University with cooperation from the University of California San Diego. the results of the study were released today in the Journal of the American Medical Association. the study, funded by the National Institutes of Health, is a randomized clinical trial of the effects of vitamin D supplementation on all types of cancer combined.
March 28, 2017
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HMS scientists reveal how certain tumors develop taste for fat
Cancers are such notorious sugar addicts that PET scans searching for the disease light up when they detect sugar-gobbling tumor cells. But a handful of cancers appear to favor fat over sugar, a propensity that has long mystified scientists. Now, a study from Harvard Medical School reveals how certain tumors develop a taste for fat as their life-sustaining fuel.
September 15, 2016
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Hope for 1st Drug Against Lymphedema
Mouse study offers clues to ease the painful, swollen limb condition
May 10, 2017
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Hormone receptor could be potential biomarker for gastric cancer, research shows
Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, the Veterans Affairs Medical Center in Miami, and Shantou University Medical College in China, have shown that the hormone receptor GHRH-R could be a potential biomarker for gastric cancer, enabling earlier diagnoses and better staging.
December 21, 2016
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Hormone replacement therapy linked to lower risk of atherosclerosis and death in women
Hormone replacement therapy has long been controversial as studies have associated it with health benefits and risks. While some studies suggest that it lowers the risk of osteoporosis and improves some aspects of heart health, others link it to higher risk of cancer and stroke.
March 9, 2017
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How a cancer gene protects genome organization
Crucial function of yeast enzyme Set2 whose well-conserved human counterpart is often mutated in cancers uncovered
June 13, 2017
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How an untested drugs scandal could lead to better clinical practice
Cancer researchers and patients from all over the world can learn valuable lessons from a recent Brazilian scientific scandal, according to a new policy paper. In Brazil, the distribution by "researchers" to patients of an untested compound called phosphoethanolamine (PHOS) led to a widely publicized scientific debacle.
October 17, 2016
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How animals keep their cells identical
Collaboration between biologists, computer scientists yields insights into some cancers and age-related diseases
July 26, 2016
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How best to treat infections and tumors: Containment versus aggressive treatment
A new mathematical analysis identifies the factors that determine whether aggressive treatments or containment strategies will perform best in treating infections and tumors, providing physicians and patients with new information to help them make difficult treatment decisions.
February 9, 2017
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How cancer cells protect chromosomes from decay
Scientists have used CRISPR gene editing technology and live cell, single molecule microscopy to watch in real-time, for the first time, the essential interaction between telomerase and telomeres.
August 18, 2016
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How cancer's 'invisibility cloak' works
Researchers have discovered how cancer cells become invisible to the body's immune system, a crucial step that allows tumors to metastasize and spread throughout the body.
September 23, 2016
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How Chinese medicine kills cancer cells
Researchers have shown how a complex mix of plant compounds derived from ancient clinical practice in China -- a Traditional Chinese Medicine -- works to kill cancer cells.
September 8, 2016
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How ionizing radiation damages DNA and causes cancer
Two characteristic patterns of DNA damage found
September 12, 2016
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How killer cells take out tumors
The use of immunotherapy to treat cancer is celebrating its first successes -- but there are still many knowledge gaps in the underlying mechanisms of action. In a study of mice with soft tissue tumors, researchers have now shown how endogenous killer cells track down the tumors with the help of dormant viruses.
June 6, 2017
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How some chickens got striped feathers
Birds show an amazing diversity in plumage color and patterning. But what are the genetic mechanisms creating such patterns? Researchers now report that two independent mutations are required to explain the development of the sex-linked barring pattern in chicken. Both mutations affect the function of CDKN2A, a tumor suppressor gene associated with melanoma in humans.
April 7, 2017
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How to shield therapeutic nanoparticles from the immune system
In the lab, doctors can attach chemotherapy to nanoparticles that target tumors, and can use nanoparticles to enhance imaging with MRI, PET and CT scans. Unfortunately, nanoparticles look a lot like pathogens - introducing nanoparticles to the human body can lead to immune system activation in which, at best, nanoparticles are cleared before accomplishing their purpose, and at worst, the onset of dangerous allergic reaction.
December 19, 2016
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Human Patient Treated with Crispr Gene Editing for the First Time
Chinese Researchers Hope the Tool will Help Fight Cancer
November 17, 2016
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Misc. - I

I beat cancer twice, but women on Facebook helped me heal
The sisterhood of the purple ribbon
March 8, 2017
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IBM's Watson may provide a shortcut to treating cancer
The tech giant's cognitive computer system will help oncologists with the data-intensive work of identifying mutations in DNA and finding specific treatments.
June 29, 2016
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IBM's Watson proves useful at fighting cancer–except in Texas
Despite early success, MD Anderson ignored IT, broke protocols, spent millions.
February 21, 2017
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IBM's Watson to use genomic data to defeat drug-resistant cancers
The five-year, $50 million project will study thousands of drug-resistant tumors
November 10, 2016
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IBM-Watson to Take on Genomic Sequencing to bring Forth a new Era of Precision Oncology
IBM Watson Health and Quest Diagnostics have joined forces to launch Watson for Genomics from Quest Diagnostics, a platform that combines genomic tumor sequencing with the computing prowess of Watson. this is the first time Watson for Genomics is made publicly available to physicians across the United States. the service will involve analysis of the genetic makeup of patient tumors to help locate and identify mutations that are associated with clinical trials and targeted therapies. Watson then takes this patient data and compares it with all the scientific literature and clinical trial data based on inputs provided by oncologists. this information can then be used by oncologists all over the country to make informed decisions about the treatment plans for these patients.
November 7, 2016
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ICR researchers identify how genetic variant linked to leukaemia helps cancer cells survive
Scientists at the Institute of Cancer Research, London, have identified how an inherited genetic variant, associated with an increased risk of developing the most common type of leukaemia, helps cancer cells survive. the findings could lead to new ways to target the disease.
August 12, 2016
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IL-34: New, possible target to tackle drug-resistant cancer cells
Chemoresistant lung cancer cells suppress immune functions and strengthen resistance to chemotherapy by producing interleukin-34 (IL-34)–a type of cytokine, a team of researchers has discovered.
October 3, 2016
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Illuminating cancer: Researchers invent a pH threshold sensor to improve cancer surgery
Researchers have invented a transistor-like threshold sensor that can illuminate cancer tissue, helping surgeons more accurately distinguish cancerous from normal tissue.
December 20, 2016
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Imaging where cancer drugs go in the body could improve treatment
Nanomedicine has the potential to help personalize cancer treatments and reduce side effects of therapeutic drugs. While some progress has been made toward the latter goal, customized treatments are still hard to come by.
October 26, 2016
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Immune cell therapy shows promising results for lymphoma patients
Physician investigators are working to bring immune cellular therapies to refractory diffuse large B-cell lymphoma patients. Promising results from the phase 1 portion of the ZUMA-1 study, which uses chimeric antigen receptor (CAR) modified T cells to treat b-cell lymphoma patients, have now been published.
January 5, 2017
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Immune system autocorrect feature reverses autoimmune disease in mice
Immunologists take page out of anti-cancer book to make disease-fighting cells.
July 7, 2016
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Immune therapy scientists discover distinct cells that block cancer-fighting immune cells
Scientists have discovered a distinct cell population in tumors that inhibits the body's immune response to fight cancer.
February 6, 2017
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'Immunoswitch' particles may be key to more-effective cancer immunotherapy
New strategy tested in animals could improve cancer immunotherapies
June 7, 2017
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'Immunoswitch' particles may be key to more-effective cancer immunotherapy
Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells'' defensive properties while switching on a robust anticancer immune response in mice. Experiments with the tiny, double-duty "immunoswitch'' found it able to dramatically slow the growth of mouse melanoma and colon cancer and even eradicate tumors in test animals, the researchers report.
June 7, 2017
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Immunotherapy cancer trials presented to key opinion leaders
Immodulon recently met with some of the world's most renowned oncologists to present their forthcoming trials for immunotherapy treatment, IMM-101. Their feedback has been extremely positive and allows Immodulon to move forward with the planning of a pivotal trial, for launch next year, as well as additional exploratory investigations of IMM-101 in combination with other treatments to begin later this year.
July 12, 2016
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Immunotherapy drug combination shows prominent therapeutic effect against advanced and metastatic cancers in mice
A drug combination designed to enhance the immune system's ability to zero in and attack cancer cells has shown a pronounced therapeutic effect against advanced and metastatic cancers in mice, according to a Mayo Clinic study, published in the July 12 edition of the online journal Oncotarget.
July 12, 2016
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Implantable nanoparticle catalyst against cancer
Assembling a drug from harmless components at the target location, such as a tumor, would help reduce the side effects of treatment. In the journal Angewandte Chemie ("Copper Catalysis in Living Systems and In Situ Drug Synthesis"), British and Malaysian scientists present a new, nontoxic catalyst made of copper nanoparticles that can be used to specifically and selectively assemble building blocks in a living system. It was shown to be possible to make an anti-tumor drug from two benign components in situ.
November 15, 2016
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Implanted scaffold with T cells rapidly shrinks tumors
A biopolymer structure enriched with nutrients shows how immunotherapy could be adapted for solid tumors, according to study in the Journal of Clinical Investigation.
April 24, 2017
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Important advance made with new approach to 'control' cancer, not eliminate it
Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment -- to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.
August 26, 2016
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Important advance made with new approach to 'control' cancer, not eliminate it
Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.
August 29, 2016
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In a sample of blood, researchers probe for cancer clues
One day, patients may be able to monitor their body's response to cancer therapy just by having their blood drawn. a new study has taken an important step in that direction by measuring a panel of cancer proteins in rare, individual tumor cells that float in the blood.
March 24, 2017
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In battle for real estate, a disordered protein wins out
New study points to potential strategy to kill cancer cells
March 8, 2017
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Incisionless robotic surgery offers promising outcomes for oropharyngeal cancer patients
An incisionless robotic surgery -- done alone or in conjunction with chemotherapy or radiation -- may offer oropharyngeal cancer patients good outcomes and survival, without significant pain and disfigurement, research finds.
September 16, 2016
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Infervision's Artificial Intelligence Software Detects Suspected Tumors on Standard Imaging Scans
Infervision, a Chinese company, has been integrating deep learning artificial intelligence to the practice of radiology in order to improve the detection rates of early stage tumors. the technology relies on analyzing tens of thousands of X-rays and CT scans that have been used to perform a diagnosis and to use that base of knowledge to evaluate future scans.
May 16, 2017
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Innovative combined therapy could effectively fight tumors
Researchers wish to treat tumors more effectively in the future by combining radiation therapy and focused ultrasound. the joint project SONO-RAY began on October 1st, 2016. the project is part of Leipzig University's Innovation Center for Computer-Assisted Surgery (ICCAS) as well as OncoRay - National Center for Radiation Research in Oncology, located in Dresden.
October 17, 2016
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Innovative nanobubble treatment finds and destroys cancer cells in mice
Innovative technology developed by NIH-funded researchers has been able to find and facilitate the killing of cancer cells in mice without harming the nearby healthy tissue. a treatment using this technology in humans could reduce the rate of cancer recurrence or metastasis.
July 7, 2016
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Innovative Testing Platform for Assessing Nanotherapeutics for Different Cancers
An innovative testing platform for the real-time assessment of effectiveness of nanomaterials in gene expression regulation has been developed by researchers at Northwestern Medicine. the outcomes of the research have been reported in Proceedings of the National Academy of Sciences and can assist in preclinical investigations and can optimize nanotherapeutics for cancers even before the clinical trial stage.
April 12, 2017
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Insight into how cancer cells behave abnormally
Scientists have shed light on the metabolic switch observed in abnormal cells like cancer. Based on experimental evidence of metabolic oscillations, they show that changes in metabolic state can be described robustly by alterations in the ability of the oscillator to resist external perturbations.
August 03, 2016
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Insights on Tumor Growth Lead to new Treatments
Recent discoveries that shed light on how tumors grow are giving doctors new tools to fight cancer. it's just the beginning and there's a long way to go, experts say, but they're hopeful about the future of cancer treatment.
February 22, 2017
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Instead of starving a cancer, researchers go after its defenses
Oxygen deprivation can propel tumor growth and spread
February 22, 2017
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Interaction among proteins that cause cancer cells to metastasize
Researchers have identified an interaction among proteins that allows cancer cells to grow and metastasize. they say the discovery may play a role in developing a better understanding of how tumors grow in a variety of malignancies, including breast, prostate, pancreatic, colon, lung and skin cancers.
March 28, 2017
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Interfacing System can Help Differentiate Single Cancerous Cell from Normal Cell Using Graphene
Researchers from the University of Illinois at Chicago have shown that they can distinguish a single hyperactive cancerous cell from a normal cell by interfacing brain cells onto graphene. this could lead to the development of a simple, noninvasive tool for early diagnosis of cancer.
December 20, 2016
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International collaboration to create new cancer models to accelerate research
An international project to develop a large, globally accessible bank of new cancer cell culture models for the research community launched today. the National Cancer Institute (NCI), part of the National Institutes of Health; Cancer Research UK, London; the Wellcome Trust Sanger Institute, Cambridge, England; and the foundation Hubrecht Organoid Technology, Utrecht, Netherlands, are joining forces to develop the Human Cancer Models Initiative (HCMI), which will bring together expertise from around the world to make about 1,000 cancer cell models.
July 11, 2016
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International project to develop globally accessible bank of new cancer cell models for research
An international project to develop a large, globally accessible bank of new cancer cell culture models for the research community launched today. the National Cancer Institute (NCI), part of the National Institutes of Health; Cancer Research UK, London, England; the Wellcome Trust Sanger Institute, Cambridge, England; and the foundation Hubrecht Organoid Technology, Utrecht, Netherlands, are joining forces to develop the Human Cancer Models Initiative (HCMI), which will bring together expertise from around the world to make about 1,000 cancer cell models.
July 12, 2016
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Interview with Harshal Shah, Head of Oncology Drug Delivery at Cambridge Consultants
Thanks to the ongoing advancements in standards of care and gradual improvements in more targeted therapeutics, some argue that cancer is slowly turning into a chronic disease, and with it bringing about a host of new challenges for oncology care. These challenges are also opening up a variety of new opportunities for technical innovations that would mediate the load on already heavily burdened healthcare systems.
May 22, 2017
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Investigation evaluates new drug in microgravity to activate immune system, help combat cancer
On Earth, research into antibody-drug conjugates to treat cancer has been around a while. The research presents a problem, though, because Earth-based laboratories aren't able to mimic the shape of the cancer cell within the body, which can sometimes produce incorrect findings. The International Space Station's unique microgravity environment allows scientists to approach the research from a new, 3-D angle.
June 15, 2017
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Investigators pinpoint cause, possible treatment for rare form of sarcoma
Researchers have discovered a potential cause and a promising new treatment for inflammatory myofibroblastic tumors, a rare soft tissue cancer that does not respond to radiation or chemotherapy.
November 22, 2016
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Iron nanoparticles make immune cells attack cancer
Iron nanoparticles can activate the immune system to attack cancer cells, according to a study led by researchers at the Stanford University School of Medicine.
September 26, 2016
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Is a new Sepsis Treatment on the Horizon?
The possibility of curing sepsis with a common vitamin has put one of history's greatest killers back in the spotlight.
April 4, 2017
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IU study shows how fruit fly growth shares biochemical similarities with cancer cells
Scientists who study a molecule known to play a role in certain types of cancers and neurodegenerative disorders have a powerful new tool to study this compound due to research conducted at Indiana University.
January 25, 2017
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Misc. - J

Jets of plasma used in arc welding may help kill cancer cells and heal wounds
JETS of plasma traditionally used in arc welding could soon be used to kill cancer cells and heal wounds.
December 9, 2016
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Misc. - K

Keep intimate life intact despite tumor surgery in the pelvis
Tumor surgery in the pelvis (urogenital and anal area) can lead to injuries of the regional nervous center and therefore to bowel and bladder incontinence and sexual function disorders. this can dramatically influence the quality of life of those affected. a device used to measure nerve function could help, say researchers.
September 13, 2016
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Key requirement for regulatory T cell function discovered
A key requirement for the function of regulatory T cells–immune cells that play a critical role in many biological processes, from suppressing inflammation and deadly autoimmunity to helping tumors evade immune attack–is now better understood thanks to new research. the findings also unravel the complex role these cells can play in the genesis and progression of certain gastrointestinal cancers.
September 22, 2016
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KU Leuven researchers use microbubbles to evaluate effectiveness of cancer radiation treatment
An interdisciplinary team of researchers at KU Leuven (University of Leuven), Belgium, have developed a new way to evaluate whether a cancer radiation treatment is effective. Their technique uses gas-filled microbubbles and ultrasonic sound waves to determine whether the radiation beams have reached the target area. this makes it easier to limit or avoid damage to healthy tissue.
August 30, 2016
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KU researcher reveals possible therapeutic intervention for 'chemobrain' in cancer patients
Findings offered by a University of Kansas researcher, identified as one of 20 'Must see Presenters' at the national meeting of the American Chemical Society in early April, suggest a possible therapeutic intervention for "chemobrain," the cognitive impairment plaguing up to a third of cancer patients following chemotherapy.
April 12, 2017
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Misc. - L

Lab-on-a-Chip breakthrough aims to help physicians detect cancer and diseases at the nanoscale
IBM scientists have developed a new lab-on-a-chip technology that can, for the first time, separate biological particles at the nanoscale and could help enable physicians to detect diseases such as cancer before symptoms appear.
August 1, 2016
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Laboratory-on-a-chip technique simplifies detection of cancer DNA biomarkers
Cancer is the second leading cause of death in the U.S., making early, reliable diagnosis and treatment a priority. Miniaturized lab-on-chip approaches are prime candidates for developing viable diagnostic tests and instruments because they are small, need only limited test volumes, and can be cost-effective. Researchers have developed just such an approach capable of processing biomolecular samples from blood.
December 13, 2016
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Laboratory-on-a-chip technique simplifies detection of cancer DNA biomarkers
Cancer is the second leading cause of death in the U.S., making early, reliable diagnosis and treatment a priority for researchers. Genomic biomarkers offer great potential for diagnostics and new forms of treatment, such as immunotherapy. Miniaturized lab-on-chip approaches are prime candidates for developing viable diagnostic tests and instruments because they are small, need only limited test volumes, and can be cost-effective.
December 13, 2016
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Large pre-ACA Medicaid expansion did not level health disparities in cancer surgery
An analysis of the New York State's Medicaid expansion, which predated the 2010 Affordable Care Act, finds substantial decrease in uninsured rate but little change in racial disparities when it comes to access to cancer surgery -- a proxy for complex cancer care.
January 24, 2017
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Legions of nanorobots target cancerous tumours with precision
Researchers from Polytechnique Montreal, Universite de Montreal and McGill University have just achieved a spectacular breakthrough in cancer research. they have developed new nanorobotic agents capable of navigating through the bloodstream to administer a drug with precision by specifically targeting the active cancerous cells of tumours.
August 15, 2016
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Ligand-baited nanosprings capture tumor-derived exosomes from a prostate cancer cell line
In a new paper in Springer's Journal of Materials Science ("Silica nanostructured platform for affinity capture of tumor-derived exosomes"), researchers at Washington State University report a new approach for the effective capture of tumor-derived exosomes from a prostate cancer cell line. Exosomes are small secreted vesicles that play a key role in intercellular communication and cancer progression.
February 21, 2017
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Limited evidence that styrene causes cancer
In 2011, the styrene, a high volume plastics chemical and animal carcinogen, was the focal point in a 'poison scandal' in the Danish media. now a registry study of more than 72,000 employees from more than 400 companies that have been exposed to styrene during production of glassfibre reinforced plastics, has not found an increased incidence of a wide range of cancer types.
February 14, 2017
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Liquid biopsies that enable screening, early detection of cancer attract attention of investors
Interest is high in the development of blood-based tests that can be used to screen individuals for cancer. that isn't new, liquid biopsy industry has attracted attention and investment for the past few years. what is changing is that investors are more interested in screening and early detection - not just monitoring. Healthcare research firm Kalorama Information made the finding in a recent report. Kalorama Information's World Market for Molecular Diagnostics report provides markets for CTC (circulating tumor cell) testing, a type of testing related to liquid biopsy. Cell-free DNA is another type of market and Kalorama has also covered that market in detail.
March 28, 2017
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'Liquid biopsy' chip uses carbon nanotubes to detect metastatic cancer cells in a drop of blood
A chip developed by mechanical engineers at Worcester Polytechnic Institute (WPI) can trap and identify metastatic cancer cells in a small amount of blood drawn from a cancer patient the breakthrough technology uses a simple mechanical method that has been shown to be more effective in trapping cancer cells than the microfluidic approach employed in many existing devices.
December 14, 2016
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Localized chemotherapy may be effective way to keep immune system intact, animal study suggests
In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.
December 22, 2016
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Long-term anti-inflammatory drug use may increase cancer-related deaths for certain patients
Other factors remain the top risk-reduction strategies both for developing cancer, premature cancer-related deaths
December 19, 2016
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Losing weight lowered levels of proteins associated with tumor growth
Obese women who lost weight significantly lowered levels of proteins in the blood that help certain tumors grow
July 14, 2016
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Low-dose chemotherapy regimens could prevent tumor recurrence in types of breast cancer, pancreatic cancer
Conventional, high-dose chemotherapy treatments can cause the fibroblast cells surrounding tumors to secrete proteins that promote the tumors' recurrence in more aggressive forms, researchers have discovered. Frequent, low-dose chemotherapy regimens avoid this effect and may therefore be more effective at treating certain types of breast and pancreatic cancer, according to a new study.
November 23, 2016
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Ludwig study shows how experimental drug can reverse effects of suppressive immune cells
A Ludwig Cancer Research study shows that an experimental drug currently in clinical trials can reverse the effects of troublesome cells that prevent the body's immune system from attacking tumors. the researchers also establish that it is these suppressive cells that interfere with the efficacy of immune checkpoint inhibitors. this class of immunotherapies lifts the brakes that the body imposes on the immune system's T cells to unleash an attack on cancer cells.
November 9, 2016
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Luminescence switchable carbon nanodots follow intracellular trafficking and drug delivery
Tiny carbon dots have, for the first time, been applied to intracellular imaging and tracking of drug delivery involving various optical and vibrational spectroscopic-based techniques such as fluorescence, Raman, and hyperspectral imaging. Researchers from the University of Illinois at Urbana-Champaign have demonstrated, for the first time, that photo luminescent carbon nanoparticles can exhibit reversible switching of their optical properties in cancer cells.
February 13, 2017
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Misc. - M

Machine learning lets scientists reverse-engineer cellular control networks
Stampede supercomputer helps researchers create tadpoles with pigmentation never before seen in nature
March 22, 2017
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Magic Mushrooms Are Weirdly Effective at Making Cancer Less Miserable
The active ingredient in magic mushrooms, psilocybin, is remarkably effective at reducing feelings of anxiety, depression, and other forms of mental anguish in cancer patients, according to a pair of new studies.
December 1, 2016
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'Magic Mushroom' Chemical Eases Cancer Despair
Hallucinogenic drug psilocybin relieved depression, anxiety quickly and lasted for months, studies found.
December 1, 2016
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Magic Mushrooms Help Cancer Patients Deal with Depression
The Hallucinogen Helped Patients Accept Death and Embrace Life
December 1, 2016
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Magnetic nanoparticles produced by bacteria could help kill cancer cells
(Nanowerk Spotlight) Photothermal therapy (PTT) is a form of cancer treatment where a therapeutic agent absorbs energy from photons, usually from near-infrared light, and dissipates it partially in the form of heat. When the therapeutic agents, for instance nanoparticles, are located in close vicinity to the tumor site, the temperature increase can lead to cell damage, i.e. it kills the cancer cell.
November 10, 2016
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Making (sound) waves in the fight against cancer
Ultrasound innovation could replace invasive biopsies
December 14, 2016
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Master detox molecule boosts immune defenses
Scientists discover an unknown immune mechanism
April 18, 2017
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Mathematical modeling can identify ways to limit aggressive tumor cell growth
Mathematical models can be used to predict how different tumor cell populations interact with each other and respond to a changing environment, research suggests.
May 24, 2017
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Mayo Clinic creates genetic test to help guide diagnosis, treatment of lymphoma patients
Mayo Clinic has created a genetic test to help guide diagnosis and treatment of patients with diffuse large B-cell lymphoma, the most common type of non-Hodgkin's lymphoma. the Lymph2Cx test helps determine where the lymphoma started, assigning "cell-of-origin" groups using a 20-gene expression-based assay.
December 16, 2016
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Mayo Clinic researchers discover potential cause and new treatment for rare soft tissue cancer
Researchers at Mayo Clinic Center for Individualized Medicine have discovered a potential cause and a promising new treatment for inflammatory myofibroblastic tumors, a rare soft tissue cancer that does not respond to radiation or chemotherapy.
November 22, 2016
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MD Anderson, ILC Dover and NASA partner to increase awareness of childhood cancer
Today, several of Space City's best-known institutions -- the University of Texas MD Anderson Cancer Center, the National Aeronautics and Space Administration (NASA) and ILC Dover -- announced a partnership that brings the benefits of arts and science to pediatric cancer patients while increasing awareness of childhood cancer. More than 530 patients, families, and staff members painted original artwork used to create full-sized suits for the Space Suit Art Project.
July 11, 2016
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Measuring patients' muscles to predict chemotherapy side effects
Measuring patients' muscle mass and quality could potentially help doctors better identify patients at high risk for toxic side effects that could require hospitalizations, researchers report.
February 22, 2017
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Medicine Nobel goes to the man who figured out how cells digest themselves
Autophagy is a basic process that may go wrong in cancer, neurodegenerative diseases.
October 3, 2016
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MedUni Vienna scientists aim to identify prognostic markers for cutaneous lymphomas
Primary cutaneous lymphomas, cancers of the lymphatic system, occur in the skin and originate either from T-lymphocytes (T-cell lymphomas, incidence 75%) or in B-cell lymphocytes (B-cell lymphomas, 25%). Lymphocytes are cells of the blood system. this is a rare disease of ultimately unknown causation.
August 30, 2016
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MEMOIR: a Novel Method for Understanding the Life History of Cells
A recent study in the journal Nature has provided proof of principle for a novel method which enables the encoding of a cell's history in its genome and the subsequent readout of the information. Called MEMOIR (Memory by Engineered Mutagenesis with Optical In situ Readout), the new technique provides insight into cellular patterns of communication, relationships between cells, and various other events of influence, reaching beyond the static view of cells that is typically obtained.
November 22, 2016
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Men with learning difficulties four times more likely to die of testicular cancer
People with learning difficulties are 4 times more likely to die of testicular cancer than the general population. this is the first work relating cancer deaths to learning difficulties, with researchers now testing if this finding applies to all cancers.
March 27, 2017
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Metabolism drives growth, division of cancer cells
The metabolic state of tumor cells contributes to signals that control the proliferation of tumor cells. In the 1920s, scientists observed that tumor cells radically change their metabolism. this process was termed "Warburg Effect", however neglected until recently by cancer research, but the latest results show it is indeed of fundamental importance for the development of aggressive tumors.
February 20, 2017
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Metabolite that promotes cancer cell transformation and colorectal cancer spread identified
The metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial--mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread. this finding highlights the value of targeting D-2HG to establish new therapeutic approaches against colorectal cancer.
December 1, 2016
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Methylation status of ten positions in genome correlates with all-cause mortality
Various chemical modifications in the genome determine whether genes are read or deactivated. Methyl labels in the DNA play a key role in this "epigenetic" regulation of gene activity. Life style and environmental factors influence the methylation in the genome. Scientists have already well documented links between the methylation status of specific positions in the genome and cancer as well as other diseases.
March 19, 2017
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MIA transport protein no longer missing in action
Breakthrough in understanding how plant makes anti-cancer compound
January 13, 2017
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Microchip for Sorting and Identifying Large Numbers of Circulating Tumor Cells
Detection and classification of circulating tumor cells (CTCs) may soon become a common method for screening for multiple types of cancer. Fluorescence-activated cell sorting (FACS) is popular one technique for spotting CTCs, but it's limited because the number of available dye colors is small and because for CTCs of certain cancers there aren't any markers at all. Since few markers exist, the signal is often vague because multiple cell types end up being collected into the same container.
June 5, 2017
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Microfluidic Device to Test Electric Fields on Cancer Cells
At the post-grad research collaboration called Singapore-MIT Alliance for Research and Technology (SMART), a team has developed a microfluidic device for testing how electric fields influence living cells. the main goal for the technology is to identify the nature of the electric fields that best disrupt the activity of cancer cells, the growth and multiplication of which has been shown in the past to be influenced by external electric fields.
July 8, 2016
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MicroRNA specifically kills cancer cells with common mutation
Approximately 20 percent of all human cancers have mutations in a gene called KRAS. KRAS-mutant cancers are among the most difficult to treat, with poor survival and resistance to chemotherapy. Researchers used microRNAs to systematically inhibit thousands of other genes to find combinations that are specifically lethal to cancer cells driven by a KRAS mutation.
October 3, 2016
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Microscopic sensor for more precise radiology treatments
A team of researchers is the first in the world to succeed in quantifying the effects of radiation on individual cancer cells. this means that radiation therapies can now be tailored to individual tumors and thus be more effective.
November 9, 2016
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Microscopic sensor for more precise radiology treatments
A team of Norwegian, French and Australian researchers is the first in the world to succeed in quantifying the effects of radiation on individual cancer cells. this means that radiation therapies can now be tailored to individual tumours and thus be more effective
November 9, 2016
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Microsoft wants to crack the cancer code using artificial intelligence
Cancer is like a computer virus and can be 'solved' by cracking the code, according to Microsoft. the computer software company says its researchers are using artificial intelligence in a new healthcare initiative to target cancerous cells and eliminate the disease.
September 20, 2016
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Microsoft's next big AI project? Helping 'solve' cancer
Microsoft has revealed its involvement in several collaborations with scientists to help fight or, as it puts it, "solve" cancer using artificial intelligence.
September 20, 2016
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Microsoft's researchers want to 'solve' cancer within 10 years
Microsoft: a technology company best known for Windows, Office, ...and curing cancer? While that last one may be very surprising, the company's claims to fame may indeed feature some medical miracles in the near future. In fact, Microsoft says it might 'solve' cancer in the next 10 years.
September 20, 2016
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Microwaves Energize Photodynamic Nanoparticles to Attack Tumor Cells
At the University of Texas at Arlington researchers are investigating using microwaves to energize photosensitive nanoparticles as a modality for killing neoplastic cells. Previously, for medical applications light has been generally used to get such particles to activate their cell killing particles.
October 19, 2016
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Mini particle accelerators make cancer treatment safer for everyone
The Korle Bu Teaching Hospital in Accra, Ghana--the third largest hospital in Africa--houses two radiation machines for treating cancer patients. Both are relatively new, purchased by Ghana's Ministry of Health in the last few years. Both produce powerful X-rays that can penetrate your skin to kill tumor cells in your body. People from all over Ghana, even outside the country, come to the hospital to use the machines for cancer therapy.
June 12, 2017
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MIT Tethers Nanoparticles to Make Cancer Cells More Vulnerable to Treatment
Researchers at MIT have developed an approach to make tumor cells more susceptible to particular types of cancer treatment by coating nanoparticles on the cells prior to delivering drugs.
March 21, 2017
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MIT researchers develop new machine to rapidly produce customized peptides
Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections.
February 27, 2017
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Mitochondria are exploited in cancer for tumor cell motility, metastatic competence
A newly identified pathway for this mechanism also provides a viable, 'drugable' target for many different types of tumors
July 7, 2016
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Mitochondrial stress induces cancer-related metabolic shifts
New findings suggest that mitochondrial stress alone can trigger the metabolic shifts that accompany tumor growth, working through a pathway that involves p53, a protein widely known to play multiple important roles in cancer.
July 7, 2016
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Mitosis study finds potential cancer target
By drilling down to the atomic level of how specific proteins interact during cell division, or mitosis, a team of scientists has found a unique new target for attacking cancer.
August 30, 2016
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Mitosis study identifies new potential target for cancer therapy
Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy.
August 31, 2016
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Modifications to protein RUNX3 may promote cancer growth
New study also identified a potential way to increase effectiveness of cancer therapy
July 15, 2016
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Modifications to RUNX3 protein may promote cancer progression
New study also identified a potential way to increase effectiveness of cancer therapy
July 18, 2016
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Moffitt Cancer Center addresses cancer-related needs and concerns of LGBTQ community
The Lesbian, Gay, Bisexual, Transgender, Queer /Questioning (LGBTQ) community is growing, with an estimated 3 to 12 percent of Americans identifying as LGBTQ. But this minority group is also medically-underserved, especially when it comes to cancer care. Moffitt Cancer Center is leading the charge to better understand the needs of this group and identify educational opportunities for healthcare providers to foster a better experience for all involved.
September 15, 2016
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Moffitt researchers discover novel way to control SETDB1 protein upregulated in cancer
Cancer is a group of more than 100 different diseases. all are driven by cells and genes that escape the normal process of division and begin their own plan to replicate in the body. Advances in genetics and molecular biology are providing researchers with better knowledge of the genetic mutations and cell alterations that can lead to cancer, and also how to utilize that information to develop preventive measures and therapies to target the diseases.
July 8, 2016
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Molecule thought to indicate good cancer prognosis can have dark side, research shows
The molecule p21WAF1/Cip1 (or p21 for short) is often found in association with a so-called 'master tumour-suppressor' p53. this has traditionally given doctors an indication that there is a good prognosis for cancer - the presence of p21 indicating that the p53 tumour suppressor will lead to a less aggressive tumour.
July 8, 2016
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More cancers diagnosed at early stage following increase in health insurance coverage
Cancer is most curable when it's detected at its earliest stages. An analysis of nearly 273,000 patients showed that between 2013 and 2014 there was a 1% increase in the percentage of breast, lung, and colorectal cancers diagnosed at the earliest, most treatable stage.
May 18, 2017
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Most cancer mutations are due to random DNA copying 'mistakes'
Scientists report data from a new study providing evidence that random, unpredictable DNA copying 'mistakes' account for nearly two-thirds of the mutations that cause cancer. Their research is grounded on a novel mathematical model based on DNA sequencing and epidemiologic data from around the world.
March 23, 2017
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Most cancer mutations result from DNA copying errors
Two thirds of the mutations that cause cancer may be due to random, unpredictable DNA copying "mistakes," according to scientists from the Johns Hopkins Kimmel Cancer Center in Baltimore, MD. These errors are reported to occur regardless of lifestyle and environmental factors.
March 24, 2017
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Most new, high-priced cancer drugs don't even extend life for 10 weeks
Patient advocates are urging FDA and drug companies to set the bar higher.
February 10, 2017
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Mouth cancer rates soar over 20 years
A new analysis reveals that rates of mouth (oral) cancer have jumped by 68 per cent in the UK over the last 20 years. the figures reveal the cancer is on the rise for men and women, young and old, climbing from eight to 13 cases per 100,000 people over the last two decades.
November 24, 2016
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MR-HIFU and ThermoDox to Treat Recurrent Childhood Tumors: Interview with AeRang Kim, Principal Investigator
Children's National Health System and the Celsion Corporation (Lawrenceville, NJ) have recently announced a Phase I clinical trial in the US to determine a safe and tolerable dose of ThermoDox in conjunction with non-invasive magnetic resonance-guided high-intensity focused ultrasound. the trial is aimed on young adults and children with recurring solid tumors.
December 6, 2016
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Muscle growth finding may assist with cancer treatment
Researchers have developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer.
June 14, 2017
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Music interventions help improve quality of life in cancer patients
We've all heard of laughter being the best medicine, but what about music?
August 17, 2016
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Misc. - N

'Nanocarriers' Loaded to Transport Cancer Drugs and Imaging Particles to Tumor Site
A conundrum of cancer is the ability of a tumor to use the human body as a human shield to deflect treatment. Tumors develop around normal organs and tissues, which gives doctors few options, but to damage, remove, or poison healthy parts of the body trying to fight back the cancer with surgery, radiation, or chemotherapy.
November 30, 2016
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Nanodiscs deliver personalized cancer therapy to immune system
Researchers at the University of Michigan have had initial success in mice using nanodiscs to deliver a customized therapeutic vaccine for the treatment of colon and melanoma cancer tumors (Nature Materials, "Designer vaccine nanodiscs for personalized cancer immunotherapy").
December 27, 2016
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Nanodiscs Train Immune System to Attack and Kill Tumors
Immunotherapy has great great potential for fighting cancer, but controlling it is difficult. at University of Michigan investigators have developed an approach that uses specially designed nanodiscs to train the immune system to attack tumors. the nanodiscs, made of synthetic high density lipoproteins, contain neoantigens, particles which trigger an immune response, of a specific tumor. These are delivered into the body to train immune system T-cells to attack that type of cancer and prevent its recurrence.
January 11, 2017
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Nanofiber scaffolds demonstrate new features in the behaviour of stem and cancer cells
Novel scaffolds are shown enabling cells to behave in a different but controlled way in vitro due to the presence of aligned, self-assembled ceramic nanofibers of an ultra-high anisotropy ratio augmented into graphene shells.
August 23, 2016
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Nanohyperthermia softens tumors to improve treatment
The mechanical resistance of tumors and collateral damage of standard treatments often hinder efforts to defeat cancers. However, a team of researchers has successfully softened malignant tumors by heating them. this method, called nanohyperthermia, makes the tumors more vulnerable to therapeutic agents. First, carbon nanotubes (CNTs) are directly injected into the tumors. Then, laser irradiation activates the nanotubes, while the surrounding healthy tissue remains intact.
January 1, 2017
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Nanohyperthermia softens tumors to improve treatment
The mechanical resistance of tumors and collateral damage of standard treatments often hinder efforts to defeat cancers. However, a team of researchers from the CNRS, the French National Institute of Health and Medical Research (INSERM), Paris Descartes University, and Paris Diderot University has successfully softened malignant tumors by heating them.
January 1, 2017
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Nanohyperthermia may prove effective as adjuvant cancer treatment with chemotherapy
The mechanical resistance of tumors and collateral damage of standard treatments often hinder efforts to defeat cancers. However, a team of researchers from the CNRS, the French National Institute of Health and Medical Research (INSERM), Paris Descartes University, and Paris Diderot University has successfully softened malignant tumors by heating them. this method, called nanohyperthermia, makes the tumors more vulnerable to therapeutic agents. First, carbon nanotubes (CNTs) are directly injected into the tumors.
January 1, 2017
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Nanomedical anti-tumor strategy
Biocompatible nanocapsules, loaded with an amino acid and equipped with an enzyme now combine two anti-tumor strategies into a synergistic treatment concept. Researchers hope this increases effectiveness and decreases side effects. In the journal Angewandte Chemie, the scientists explain the concept: tumor cells are deprived of their nutrient glucose as this is converted to toxic nitrogen monoxide and hydrogen peroxide.
December 12, 2016
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Nanoparcel to Destroy Hypoxic Cancer Cells
A majority of cancer tumors contain regions of low oxygen concentration where cancer treatments based on the action of reactive oxygen species are unproductive. Recently, American researchers have created a hybrid nanomaterial that discharges a free-radical-generating prodrug within tumor cells upon thermal activation.
May 5, 2017
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Nanoparticle aggregates for destruction of cancer cells
An international team has shown that it is possible to mechanically destroy cancer cells by rotating magnetic nanoparticles attached to them in elongated aggregates.
June 13, 2017
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Nanoparticle delivers cancer drugs to tumor blood vessels
In a set of studies in mice bearing human tumors, nanoparticles designed to bind to a protein called P-selectin successfully delivered both chemotherapy drugs and targeted therapies to tumor blood vessels. Targeting the blood vessels improved the delivery of drugs to tumor tissue, causing the tumors to shrink and improving how long the mice lived.
August 10, 2016
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Nanoparticle Drug Cocktail Optimizes Checkpoint Blockade Immunotherapy for Potential Treatment of Cancers
Over the past few years there has been a lot of excitement regarding cancer treatments capable of mobilizing the body's immune system to fight the disease. Checkpoint blockade is one of the promising types of immunotherapy. Although this therapy has shown remarkable successes, checkpoint blockade therapy is not able to tackle some of the most fatal kinds of tumors.
September 19, 2016
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Nanoparticle that mimics salmonella counteracts chemotherapy resistance
Researchers at the University of Massachusetts Medical School have designed a nanoparticle that mimics the bacterium Salmonella and may help to counteract a major mechanism of chemotherapy resistance.
August 22, 2016
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Nanoparticle vaccine shows potential as immunotherapy to fight multiple cancer types
Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types.
April 24, 2017
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Nanoparticle vaccine shows potential as immunotherapy to fight multiple cancer types
A first-of-its-kind nanoparticle vaccine immunotherapy has been developed that targets several different cancer types, outlines a new report.
April 24, 2017
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Nanoparticles Feature Two Mechanisms to Boost Effectiveness of Immunotherapy to Fight Cancer
Immunotherapy techniques for fighting cancer generally fall into two categories: preventing tumor cells from evading the immune system's T cells and summoning T cells to attack the tumors. Now scientists at Johns Hopkins University School of Medicine have developed nanoparticles that perform both tasks at the same time, significantly improving the effectiveness of immunotherapy in a study on laboratory mice.
June 12, 2017
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Nanoparticles Made of Building Blocks Integrate Multiple Chemo Agents
Researchers at MIT have developed a method of creating nanoparticles that can carry three or more different chemo drugs simultaneously into a tumor. Moreover, in an unusual twist, it seems like the drugs ended up acting differently than when delivered systemically, pointing to the delivery method affecting how a medication actually behaves.
September 21, 2016
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Nanoparticles reprogram immune cells to fight cancer
Researchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.
April 17, 2017
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Nanoparticles Reprogram Immune Cells to Fight Cancer
Dr. Matthias Stephan visualizes a future where patients with leukemia could be treated as early as the day they are diagnosed with cellular immunotherapy that is accessible even at their neighborhood clinic and is as simple to administer as present day chemotherapy, but without the severe side effects.
April 18, 2017
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Nanoparticulate Delivery Systems Allow Selective Targeting of Cancer Cells
Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. It is a leading cause of death and the burden is expected to grow worldwide due to the growth and aging of the population, mainly in less developed countries, in which about 82% of the world's population resides.
March 8, 2016
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Nanopolymer-Altered Protein Array can Detect Cancer
An innovative technique to detect particular types of proteins that act as indicators for cancer and other diseases was recently developed by a biochemist at Purdue University.
November 17, 2016
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Nanopolymer-modified protein array can pinpoint hard-to-find cancer biomarker
A Purdue University biochemist has developed a novel method for detecting certain types of proteins that serve as indicators for cancer and other diseases.
November 16, 2016
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Nanopores could map small changes in DNA that signal big shifts in cancer
Detecting cancer early, just as changes are beginning in DNA, could enhance diagnosis and treatment as well as further our understanding of the disease. a new study by University of Illinois researchers describes a method to detect, count and map tiny additions to DNA called methylations, which can be a warning sign of cancer, with unprecedented resolution.
April 13, 2017
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Nanorobotic agents designed to travel in the human body to treat cancer
Fifty years to the day after the film Fantastic Voyage was first shown in theatres, the Polytechnique Montreal Nanorobotics Laboratory is unveiling a unique medical interventional infrastructure devoted to the fight against cancer. the outcome of 15 years of research conducted by Professor Sylvain Martel and his team, it enables microscopic nanorobotic agents to be guided through the vascular systems of living bodies, delivering drugs to targeted areas.
August 24, 2016
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Nanoscale ultrasound technique is first to image inside live cells
Researchers at the University of Nottingham have developed a break-through technique that uses sound rather than light to see inside live cells, with potential application in stem-cell transplants and cancer diagnosis.
December 21, 2016
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Nanoscience to Make Major Contributions in Health Care in the Coming Decade
Nanoscience research includes molecules that are only 1/100th the size of cancer cells and these molecules have the ability to improve the quality of our lives and our health. Currently, nine leading nanoscientists foresee what we can expect in the future, and conclude that nanoscience is ready to make significant contributions in various areas, including electronics, health care, food, water and energy.
October 27, 2016
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Nanosized silicon heater and thermometer combined to fight cancer
Russian physicists from ITMO University have found out that spherical silicon nanoparticles can be effectively heated up, and simultaneously emit light depending on their temperature. According to the scientists, these properties coupled with a good biocompatibility will allow usage of the semiconductor nanoparticles in photothermal therapy and nanosurgery.
May 31, 2017
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Nanosubmarine with self-destroying activity
Self-destroyed redox-sensitive stomatocyte nanomotor delivers and releases drugs for cells
May 30, 2017
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Nanotechnology Expert Sadik Esener Roped in to Direct OHSU's Center for Early Detection Research
A scientific innovator, whose achievements range from developing diagnostic biochips to creating nanoscale cancer-fighting "smart bullets" that deliver treatments to tumor cells, has been recruited to the OHSU Knight Cancer Institute to lead the first large-scale early cancer detection program of its kind.
March 8, 2016
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Nanotechnology-based approach to repair the cancer cell suicide mechanism
Cancer is a very complex disease and the exact cause is not clearly understood yet. Extensive biomedical research suggests a combination of genetic and environmental factors. Treatment for cancer can be of many types and primarily depends on the type of the disease, its progression and other factors.
July 6, 2016
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Nanotube chip captures and analyzes circulating tumor cells in blood
(Nanowerk Spotlight) Early and accurate detection of cancer is critical for successful cancer therapies. In most cases, a tissue biopsy is the initial means of making a diagnosis. with increasing accuracy, liquid biopsies -- where circulating tumor cells (CTCs) are isolated from blood samples -- are becoming a viable complement or even alternative to invasive biopsies of metastatic tumors.
October 5, 2016
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Nanovaccine could enhance cancer immunotherapy, reduce side effects
National Institute of Biomedical Imaging and Bioengineering researchers have created a nanovaccine that could make a current approach to cancer immunotherapy more effective while also reducing side effects. the nanovaccine helps to efficiently deliver a unique DNA sequence to immune cells -- a sequence derived from bacterial DNA and used to trigger an immune reaction. the nanovaccine also protects the DNA from being destroyed inside the body, where DNA-cutting enzymes are pervasive, as well as outside of the body when exposed to warm temperatures while being stored or transported.
August 24, 2016
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Nanovaccine shows potential as immunotherapy for cancer
For the first time, researchers have shown that using a nanovaccine to deliver cancer immunotherapy can slow tumor growth and prolong survival in mouse models of several types of cancer.
April 25, 2017
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Natural kill cell technology to stop cancer gets licensed
Our bodies contain Natural Killer (NK) cells - an army that stops cancers and viruses before they can make us sick. a researcher from the University of Central Florida's College of Medicine has created a nanoparticle that increases the number of these killers 10,000-fold in the lab and her new technology has generated a licensing agreement that is expected to accelerate the therapy's path to clinical trials.
December 14, 2016
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Naturally occurring symptoms may be mistaken for tamoxifen side-effects
Women taking tamoxifen to prevent breast cancer were less likely to continue taking the drug if they suffered nausea and vomiting, according to new data.
December 9, 2016
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NCI embraces scientific road map to achieve Cancer Moonshot goals
National Cancer Institute Acting Director Douglas Lowy, M.D., today accepted the recommendations of a Blue Ribbon Panel on 10 scientific approaches most likely to make a decade's worth of progress against cancer in five years under the Cancer Moonshot. T
September 7, 2016
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NCI launches study of African-American cancer survivors
The largest study to date of African-American cancer survivors in the United States is underway. the Detroit Research on Cancer Survivors (ROCS) study, which will include 5,560 cancer survivors, will support a broad research agenda looking at the major factors affecting cancer progression, recurrence, mortality, and quality of life among African-American cancer survivors. the effort is funded by the National Cancer Institute (NCI), part of the National Institutes of Health.
February 27, 2017
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Neu5Gc common in red meat increases risk of tumor formation
Neu5Gc, a non-human sialic acid sugar molecule common in red meat that increases the risk of tumor formation in humans, is also prevalent in pig organs, with concentrations increasing as the organs are cooked, a study by researchers from the UC Davis School of Medicine and Xiamen University School of Medicine has found.
October 19, 2016
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Neurofeedback shows promise in reducing symptoms of CIPN in cancer survivors
A type of functional brain training known as neurofeedback shows promise in reducing symptoms of chemotherapy-induced nerve damage, or neuropathy, in cancer survivors, according to a study by researchers at the University of Texas MD Anderson Cancer Center. the pilot study, published in the journal Cancer, is the largest, to date, to determine the benefits of neurofeedback in cancer survivors.
March 3, 2017
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Neurons support cancer growth throughout the body
Cancer cells rely on the healthy cells that surround them for sustenance. Tumors reroute blood vessels to nourish themselves, secrete chemicals that scramble immune responses, and, according to recent studies, even recruit and manipulate neurons for their own gain. this pattern holds true not just for brain cancers, but also for prostate cancer, skin cancer, pancreatic cancer, and stomach cancer.
February 13, 2017
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New algorithms may revolutionize drug discoveries, and our understanding of life
A new set of machine learning algorithms that can generate 3-D structures of tiny protein molecules may revolutionize the development of drug therapies for a range of diseases, from Alzheimer's to cancer.
February 7, 2017
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New approach could overcome large immunosuppressive tumors
Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.
October 22, 2016
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New approach could potentially prevent muscle wasting in muscular dystrophy and cancer
Monash University's Biomedicine Discovery Institute (BDI) researchers have collaboratively developed a therapeutic approach that dramatically promotes the growth of muscle mass, which could potentially prevent muscle wasting in diseases including muscular dystrophy and cancer.
June 14, 2017
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New approach in T-cell therapy to treat cancer
Scientists have armed immune cells with a new surface molecule. This causes the cells to respond particularly aggressively when they encounter a protein that tumors actually use to camouflage themselves from the immune system.
June 8, 2017
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New article explores cost-effectiveness of initial diagnostic protocols for microscopic hematuria
Detecting red blood cells in the urine of asymptomatic patients who don't see blood when they urinate (asymptomatic microscopic hematuria) is common but it can signal cancer in the genitourinary system.
April 17, 2017
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New autoimmune disease triggered by thymomas
A newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland), a research group has discovered. These underlying mechanisms could help to understand and develop a treatment for similar autoimmune diseases.
March 2, 2017
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New bioinformatics tool can analyse 40,000 proteins per minute
Created by a multidisciplinary team at the UPV/EHU-University of the Basque Country, it analyses 40,000 proteins per minute
June 30, 2016
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New Cancer Therapy Leaves Three Dead
Clinical trials of a promising new therapy, in which white blood cells are reprogrammed to attack cancer cells, has resulted in the deaths of three patients. In response, the US Food and Drug Administration has ordered a temporary halt to the trial.
July 8, 2016
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New cellular imaging paves way for cancer treatment
Researchers have pioneered a technique which uses florescent imaging to track the actions of key enzymes in cancer, genetic disorders and kidney disease.
June 8, 2017
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New cellular target may put the brakes on cancer's ability to spread
Promising way to curb signals that trigger metastasis
May 26, 2017
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New class of materials could revolutionize biomedical, alternative energy industries
Polyhedral boranes, or clusters of boron atoms bound to hydrogen atoms, are transforming the biomedical industry. These humanmade materials have become the basis for the creation of cancer therapies, enhanced drug delivery and new contrast agents needed for radioimaging and diagnosis. Now, a researcher has discovered an entirely new class of materials based on boranes that might have widespread potential applications, including improved diagnostic tools for cancer and other diseases as well as low-cost solar energy cells.
January 25, 2017
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New coaching program aims to help family caregivers of cancer patients stay healthy
UAB School of Nursing postdoctoral fellow J. Nicholas Dionne-Odom, Ph.D., has received a five-year, $935,000 K99/R00 Pathway to Independence Award from the National Institute of Nursing Research to develop a palliative care health-coaching program for family caregivers of persons with advanced cancer.
July 6, 2016
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New color-coding tool sheds light on blood disorders, cancers by tracking clonal stem cells
A new color-coding tool is enabling scientists to better track live blood stem cells over time, a key part of understanding how blood disorders and cancers like leukemia arise, report researchers in Boston Children's Hospital's Stem Cell Research Program.
November 22, 2016
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New device could revolutionize drug delivery to treat cancer and other diseases, study shows
A new study by Lyle Hood, assistant professor of mechanical engineering at the University of Texas at San Antonio (UTSA), describes a new device that could revolutionize the delivery of medicine to treat cancer as well as a host of other diseases and ailments. Hood developed the device in partnership with Alessandro Grattoni, chair of the Department of Nanomedicine at Houston Methodist Research Institute.
December 1, 2016
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New discovery could have major impact on therapies to prevent spread of cancer
A research study led by University of Minnesota engineers gives new insight into how cancer cells move based on their ability to sense their environment. The discovery could have a major impact on therapies to prevent the spread of cancer.
June 6, 2017
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New discovery in understanding chemotherapy resistance could prevent cancer cells fighting back
Scientists have discovered the key to preventing resistance to common chemotherapy used to treat breast and colon cancer, offering hope to an improvement to cancer care.
October 28, 2016
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New discovery opens new therapeutic opportunities for treatment of cancer and tissue fibrosis
Researchers from the Turku Centre for Biotechnology (BTK) in Finland have discovered that a cellular fuel sensor, known to control energy processes in the cells, is involved in the regulation of the contact of cells with their surrounding environment. this unexpected link could help scientists better understand life-threatening diseases, such as cancer and tissue fibrosis.
March 29, 2017
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New drug delivery system slows and controls tumors not aiming for complete elimination
Researchers have created a new drug delivery system that could improve the effectiveness of an emerging concept in cancer treatment - to dramatically slow and control tumors on a long-term, sustained basis, not necessarily aiming for their complete elimination.
August 26, 2016
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New Drug Formulary will Help Expedite Use of Agents in Clinical Trials
The National Cancer Institute (NCI) today launched a new drug formulary (the "NCI Formulary") that will enable investigators at NCI-designated Cancer Centers to have quicker access to approved and investigational agents for use in preclinical studies and cancer clinical trials. the NCI Formulary could ultimately translate into speeding the availability of more-effective treatment options to patients with cancer.
January 11, 2017
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New drugs that target neighbour proteins may help halt cancer progression
Cancer is caused by an accumulation of genetic changes in a cell, that overcome the normal checks and balances leading to uncontrolled growth. a complex, interacting network of proteins controls all of a cell's processes, from metabolism to growth and division.
January 24, 2017
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New Eczema Drug Promising in Early Trial
Nemolizumab significantly reduced the itch and improved appearance of skin
March 2, 2017
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New Environmentally Friendly Method to Make Nanoclusters of Zinc Peroxide
Anticancer nanomaterials have been created by a team of researchers at Aalto University, Finland by simulating the volcano-induced dynamic chemistry of the deep ocean.
May 15, 2017
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New ESE guidelines provide evidence-based recommendations for handling adrenal incidentalomas
The appropriate clinical response to adrenal incidentaloma should depend on the likelihood of malignancy, according to new guidelines published today by the European Society of Endocrinology (ESE), in collaboration with the European Network for the Study of Adrenal Tumours (ENSAT) and first presented at ESE's annual European Congress of Endocrinology in May 2016.
July 12, 2016
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New fiber optic probe brings endoscopic diagnosis of cancer closer to the clinic
Compact handheld probe can be used for microscopic analysis of tissue without any special stains or preparation
April 27, 2017
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New florescent imaging technique tracks actions of key enzymes in cancer, kidney disease
Researchers at the Universities of York and Leiden have pioneered a technique which uses florescent imaging to track the actions of key enzymes in cancer, genetic disorders and kidney disease.
June 8, 2017
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New gene fusions, mutations linked to gastrointestinal stromal tumors
In recent years, researchers have identified specific gene mutations linked to gastrointestinal stromal tumors (GIST), which primarily occur in the stomach or small intestine, but 10 to 15 percent of adult GIST cases and most pediatric cases lack the tell-tale mutations, making identification and treatment difficult. Researchers have identified new gene fusions and mutations associated with this subset of GIST patients.
December 14, 2016
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New genes identified that regulate the spread of cancers
Study reveals Spns2 gene as a new drug target
January 11, 2017
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New genomic sequencing approach could be first step toward blood tests for early cancer detection
"We continue to see promising reports about possible uses of circulating tumor DNA analysis. While this approach has a ways to go before it becomes a proven technology for early cancer detection, this research is an important step in that direction," said ASCO Expert John Heymach, MD, PhD.
June 5, 2017
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New Guidelines on Post-Treatment Cancer Pain
Specialists urge doctors to offer alternative therapies for this widespread problem
July 29, 2016
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New hope for multiple cancers with pembrolizumab combination therapies
The combination of pembrolizumab and the checkpoint inhibitor known as epacadostat is leading to promising responses and is generally well tolerated in patients with triple-negative breast cancer, non-small cell lung cancer, squamous cell cancer of the head and neck, and several other cancers, according to researchers.
May 30, 2017
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New HPV vaccine could prevent most infections and millions of cancers
Cervical cancer affects more than half a million women and causes more than a quarter of a million deaths each year globally. Almost all cervical cancers result from a human papillomavirus, or HPV, infection. HPV infections cause cancers in other parts of the body, too. But the latest HPV vaccine could prevent most infections -; and millions of cancers -; worldwide, according to an article by Cosette Wheeler, PhD, and her collaborators.
June 13, 2017
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New imaging project for new applications in cancer diagnostics
The project, funded by the EU Horizon 2020 scheme, brings a consortium of 20 companies, including technology giants Phillips and Siemens to take developments in engineering and Magnetic Resonance Imaging (MRI)and develop Magnetic Resonance Force (MRF) Imaging for new applications in cancer diagnostics.
March 27, 2017
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New Implantable Capsule for Killing Tumors, Managing Chronic Diseases
Researchers from University of Texas at San Antonio and Houston Methodist Research Institute have developed a new injectable drug delivery capsule that can administer medication locally for extended periods of time. the device, reported on in Journal of Biomedical Nanotechnology, has approximately 5,000 microscopic channels through which a drug is pumped and a special membrane that regulates how fast the medication is delivered.
December 9, 2016
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New insight into how cancer spreads
Discovery could also benefit regenerative medicine therapies
June 6, 2017
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New insights into potent cancer tumor suppressor gene
TP53 is one of the most potent genes in the human genome at preventing cancer and hence is termed a tumor suppressor gene, explain researchers. the TP53 gene has even greater anti-cancer activity than previously thought, a new study suggests.
September 22, 2016
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New mechanobiology technique to stop cancer cell migration
Researchers at the Okinawa Institute of Science and Technology Graduate University have developed a novel technique that stops cervical cancer cell migration. the research, published in Chem could open up new avenues in cancer treatment.
February 10, 2017
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New method heats up ultrasonic approach to treating tumors
Researchers apply new modeling tools to improve acoustic simulations and design a new focusing method for potential clinical treatments
March 28, 2017
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New method reduces adverse effects of rectal cancer treatment
Short-course preoperative radiotherapy combined with delayed surgery reduces the adverse side-effects of rectal cancer surgery without compromising its efficacy, report scientists.
February 10, 2017
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New methodology enables real-time tracking of proton induced radiation chemistry in water
Proton therapy is a promising form of radiation treatment used to kill cancerous cells and effectively halt their rapid reproduction. While this treatment can also be delivered in different modalities (i.e. electrons and X-rays), proton therapy limits damage to healthy tissue by depositing energy in a highly localized dose volume.
March 28, 2017
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New microfluidic device allows scientists to use safe electric fields to treat cancer
Researchers at MIT's research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells. they observed that a range of low-intensity, middle-frequency electric fields effectively stopped breast and lung cancer cells from growing and spreading, while having no adverse effect on neighboring healthy cells.
July 7, 2016
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New microfluidic device offers means for studying electric field cancer therapy
Low-intensity fields keep malignant cells from spreading, while preserving healthy cells
July 6, 2016
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New minimally invasive device to treat cancer and other illnesses
Medicine diffusion capsule could locally treat multiple ailments and diseases over several weeks
December 2, 2016
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New molecules kill multidrug resistant cancer cells
Newly discovered molecules can kill multidrug resistant cancer cells by blocking cells' defenses against cancer drugs, according to a new study. the lead author hopes the findings provide an initial step towards more effective treatments in the future against resistant cancers.
July 14, 2016
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New Nanorobotic Agents Precisely Administer Anti-Cancer Drugs
A research team from Polytechnique Montreal, McGill University, and Universite de Montreal has successfully developed novel nanorobotic agents that travel through the bloodstream and precisely inject a drug by targeting the active regions of cancerous tumors. the study represents a scientific breakthrough in cancer research.
August 16, 2016
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New Nanosensors for Measuring Enzyme Levels, Help Choose Appropriate Cancer Treatments
An MIT research team has built nanosensors capable of profiling tumors and may help to discover how they will react to certain therapies. the system is designed according to levels of enzymes known as proteases, which cancer cells use to remodel their surroundings.
September 29, 2016
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New nanostructured drug delivery system shows promise for fighting solid tumors
A new cancer-drug delivery system shows the ability to exploit the oxygen-poor areas of solid tumors that make the growths resistant to standard chemotherapy and radiation treatment.
April 4, 2017
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New NCCN Imaging AUC released for eight new cancers
The National Comprehensive Cancer Network®, a Centers for Medicare & Medicaid Services (CMS)-approved provider-led entity for imaging appropriate use criteria, continues to build its library of AUC and has published NCCN Imaging Appropriate Use Criteria for eight new cancer types. Launched in June 2016, NCCN Imaging AUC™ currently are available for 20 cancer types.
August 29, 2016
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New non-invasive method may help treat people with inoperable or hard-to-reach tumors
Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells. His discovery, described in a new study in the Journal of Clinical Oncology, may tremendously help people with inoperable or hard-to-reach tumors, as well as young children stricken with cancer.
June 28, 2016
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New pharmacon allows testicular tumors to shrink
Positive effects in mice
December 28, 2016
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New plasmonic sensor improves early cancer detection
A new plasmonic sensor will serve as a reliable early detection of biomarkers for many forms of cancer and eventually other diseases.
May 30, 2017
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New plasmonic sensor improves early cancer detection
A new plasmonic sensor developed by researchers at the University of Illinois at Urbana-Champaign will serve as a reliable early detection of biomarkers for many forms of cancer and eventually other diseases.
May 30, 2017
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New possible target for cancer treatment
Scientists report that cancer cells and normal cells use different 'gene switches' in order to regulate the expression of genes that control growth. In mice, the removal of a large regulatory region linked to different types of cancer caused a dramatic resistance to tumor formation, but did not affect normal cell growth. The findings highlight the possibility of developing highly specific cancer drugs with fewer side effects.
June 6, 2017
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New potential treatment for cancer metastasis identified
Breast cancer metastasis, the process by which cancer spreads, may be prevented through the new use of a class of drugs already approved by the US Food and Drug Administration, say investigators.
January 9, 2017
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New prognostic tool accurately predicts recurrence of parathyroid cancer
A newly-created prognostic tool reliably predicts the recurrence of parathyroid cancer, enabling physicians to identify patients at the highest risk. Consequently, the tool also helps to determine the optimum postoperative strategy, including aggressive surveillance and additional treatments, according to study results published online as an "article in press" on the Journal of the American College of Surgeons website ahead of print publication.
April 28, 2017
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New project to develop new device that delivers photo-induced cancer therapy
Physicists from the University of Texas at Arlington are leading a multidisciplinary project with the University of Texas Southwestern Medical Center in Dallas and the University of Texas MD Anderson Cancer Center in Houston to develop a new multifunctional platform that can integrate imaging and photo-induced cancer therapy in a single, portable device.
August 05, 2016
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New protein discovered in aging, cancer
A protein has been found to have a previously unknown role in the ageing of cells, according to an early study. the researchers hope that the findings could one day lead to new treatments for aging and early cancer.
March 7, 2017
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New report estimates burden of cancer in Ontario from environmental carcinogens
Between 3,540 and 6,510 new cancer cases in Ontario each year result from environmental factors, says a new report from Cancer Care Ontario and Public Health Ontario (PHO).
August 09, 2016
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New report reveals 25% drop in overall cancer death rate in the U.S.
A steady decline over more than two decades has resulted in a 25% drop in the overall cancer death rate in the United States. the drop equates to 2.1 million fewer cancer deaths between 1991 and 2014.
January 5, 2017
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New research highlights need to abandon modern hygiene hypothesis
The July issue of Perspectives in Public Health (published by the Royal Society of Public Health) takes an objective view of ongoing research showing that the hygiene hypothesis -- the idea that allergies are the price we are paying for our "modern obsession with cleanliness" -- is a misleading misnomer. not only does it undermine attitudes to hygiene at a time when antibiotic resistance threatens our ability to treat infections, it also hinders the search for ways to reverse the recent dramatic rise in allergies and other chronic inflammatory diseases.
July 6, 2016
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New research paves way for anti-cancer treatment
A new lab technique has been created that may aid the development and success rate of an important anti-cancer treatment, report scientists.
October 28, 2016
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New research shows that nuts can inhibit growth of cancer cells
Roasted and salted, ground as a baking ingredient or fresh from the shell - for all those who enjoy eating nuts, there is good news from nutritionists at Friedrich Schiller University Jena (Germany). Their latest research shows that nuts can inhibit the growth of cancer cells.
February 6, 2017
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New study aims to better understand major factors affecting African American cancer survivors
The Karmanos Cancer Institute and Wayne State University School of Medicine will launch the nation's largest study of African American cancer survivors to better understand disproportionately high incidence and mortality from cancer and its impact on this specific patient population.
February 27, 2017
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New study assesses biological impact of meditation and vacation
Scientists from the Icahn School of Medicine at Mount Sinai, the University of California, San Francisco, and Harvard Medical School used a rigorous study design to assess the biological impact of meditation compared to vacation. they examined the effect of meditation on gene expression patterns in both novice and regular meditators.
August 30, 2016
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New study discloses role of specific proteins in killing fast-duplicating cancer cells
Many cancer patients struggle with the adverse effects of chemotherapy, still the most prescribed cancer treatment. for patients with pancreatic cancer and other aggressive cancers, the forecast is more grim: there is no known effective therapy.
March 27, 2017
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New study illuminates dark side of p53 gene in cancer
The gene p53 is the most commonly mutated gene in cancer - it is p53's job to monitor cells for DNA damage and to mark damaged cells for destruction and so cancer cells with mutated DNA must disable p53 before it disables them. However, there is a second, darker side to p53. While intact or "wild type" p53 is a tumor suppressor, mutated p53 can itself become an oncogene, driving the progression of the disease.
April 3, 2017
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New study links 'mastermind' gene to rare cancer-causing tumor
Scientists have discovered a new "mastermind fusion gene" may be associated with a rare cancer-causing tumor -- pheochromocytomas ("pheo") and paragangliomas -- according to a study. this breakthrough discovery could lead to more precise treatment as well as a better understanding of cancer itself.
February 13, 2017
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New study offers hypothesis why obese patients fare worse during cancer treatment
Across many cancer types, obese patients fare worse than leaner patients. now a University of Colorado Cancer Center study published in the journal Cell Stem Cell offers a compelling hypothesis why: researchers found that leukemia stem cells "hide" in fatty tissue, even transforming this tissue in ways that support their survival when challenged with chemotherapy. It is as if leukemia stem cells not only use fatty tissue as a robbers' cave to hide from therapy, but actively adapt this cave to their liking.
July 21, 2016
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New study uses evolutionary theory to predict cancer risk in patients with Barrett's esophagus
A disorder known as Barrett's esophagus affects some 200,000 Americans each year. the condition, which is caused by stomach acid damaging the lining of the esophagus, can lead to the development of a serious, potentially fatal cancer of epithelial tissue, known as esophageal adenocarcinoma.
August 25, 2016
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New technique can effectively identify cancer-causing substances in urine or blood
A team of researchers, led by Professor Yoon-Kyoung Cho of Life Science at UNIST has recently developed a new technique that effectively identifies cancer-causing substances in the urine or blood.
March 7, 2017
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New technique efficiently separates circulating tumor cells in bloodstream
A new research, affiliated with UNIST has been highlighted on the front cover of the January 2017 issue of the prestigious journal Analytical Chemistry. the key finding of this study is the development of a new technique that seperates circulating tumor cells (CTCs) from whole blood at a liquid-liquid interface.
February 7, 2017
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New technique for imaging cells, tissues under the skin
A team of scientists has developed the first technique for viewing cells and tissues in three dimensions under the skin. the work could improve diagnosis and treatment for some forms of cancer and blindness.
March 18, 2016
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New technique sorts drivers from passengers in cancer genomics, implicates GON4L
A new study demonstrates a novel method for sorting passenger from driver alterations, and uses this method to pinpoint a new driver and potential therapeutic target in cancer progression, GON4L.
June 29, 2016
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New Technique Tags Cancer Drugs to see Whether they Penetrate Tumors
Knowing whether a drug is actually penetrating a tumor can help decide whether to have the patient continue receiving the medication or to switch to a different one. Currently, only visualizing the tumor shrinkage long after the side effects have kicked in lets doctors know about the therapeutic response. now an international team of researchers is reporting on a new imaging technique that can spot whether certain cancer drugs are actually ending up in the desired parts of the body.
October 28, 2016
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New technique uses nanoparticle-carrying immune cells to deliver anti-cancer drugs
Some researchers are working to discover new, safer ways to deliver cancer-fighting drugs to tumors without damaging healthy cells. Others are finding ways to boost the body's own immune system to attack cancer cells. Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer-fighting drugs and incorporating them into immune cells to create a smart, targeted system to attack cancers of specific types.
January 4, 2017
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New technologies show brain tumor firmness, adhesion before surgery
It's not often that a fall saves someone's life. Helen Powell, 74, says that was the case for her. a computerized tomography scan that followed her fall revealed a cancerous brain tumor that led her to surgery using first-in-the-world technology.
May 3, 2017
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New Tests and Treatments for Childhood Cancer
When doctors found a mass on the kidney of Heather Garnett's son, they wasted no time starting his care. "His tumor had ruptured, so they wanted to get it out quickly. they found it on a Tuesday and had the surgery right away on Thursday," says Garnett, an account manager and 39-year-old mother of three in Minneapolis.
February 2, 2017
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New tool helps measure how costs of care impact cancer patients
For many patients, the uncertainty and stress that can come with cancer treatment is compounded by what is now known as "financial toxicity," the anxiety and distress that follow health care and medication expenses, often compounded by reduced ability to work.
October 7, 2016
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New treatment developed to prevent nausea, vomiting caused by chemo
A drug that blocks neurotransmitters could reduce nausea and vomiting caused by chemotherapy, new research has found.
July 20, 2016
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New treatment may help those with rare immune cancers
New research may help those with advanced mastocytosis and possibly many more people. Mastocytosis is a rare disease of the immune system in which the body produces too many abnormal mast cells. Mast cells control allergic and inflammatory responses. Research on a new drug shows that it may prolong life significantly and improve quality of life.
September 6, 2016
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New tumor target strategy halts human cancer in up to 90% of mice
Using a similar treatment in humans may be effective at fighting cancer.
December 14, 2016
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New tumor-shrinking nanoparticle to fight cancer, prevent recurrence
A new type of cancer-fighting nanoparticle has been created by researchers, aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease.
May 1, 2017
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New type of immunological treatment of cancer?
Researchers have found an important piece of the puzzle leading towards an understanding of how our innate immune system reacts against viral infections and recognises foreign DNA, for example from dying cancer cells. the discovery may prove to be of great importance for immunological treatment of cancer as well as autoimmune diseases in the future.
February 21, 2017
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New type of nanoparticles can deliver chemotherapy efficiently to cancer cells
Engineering researchers at the University of Texas at Austin have developed a new method that delivers chemotherapy directly and efficiently to individual cells. the approach, described in the Sept. 8 edition of the Journal of the American Chemical Society, could provide a faster means of targeting and killing cancer cells with significantly lower doses of chemo than conventional drug delivery methods, which could decrease side effects for patients.
October 4, 2016
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New ultrasound technique is first to image inside live cells
Researchers have developed a breakthrough technique that uses sound rather than light to see inside live cells, with potential application in stem-cell transplants and cancer diagnosis.
December 21, 2016
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New way to predict tumor growth described by research study
Researcher's algorithm can aid doctors in judging the best treatment options
April 18, 2017
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New way to produce protein antigen may lead to preventative vaccine for schistosomiasis
Cornell and Ludwig Institute for Cancer Research scientists have developed a way to produce a protein antigen that may be useful as vaccine for schistosomiasis -- a parasitic disease that infects millions of people, mostly in tropical and subtropical climates -- according to new research in the journal Protein Expression and Purification, June 2017.
June 12, 2017
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New way to speed search for cancer cures dramatically
New technique will help doctors customize treatments to benefit patients
April 25, 2017
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Newfound effect of cancer drug may expand its use
A drug first designed to prevent cancer cells from multiplying has a second effect: it switches immune cells that turn down the body's attack on tumors back into the kind that amplify it.
February 10, 2017
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Newfound role for PARP proteins could lead to therapeutic opportunities for cancer
Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.
August 16, 2016
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Newly Developed Nanoparticle Vaccine Immunotherapy Targets Multiple Cancer Types
A first-of-its-kind nanoparticle vaccine immunotherapy targeting several cancer varieties has been developed by researchers from UT Southwestern Medical Center.
April 25, 2017
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Newly identified pathway in mitochondria fuels tumor progression across cancer types
Scientists have identified a novel protein pathway across several types of cancer that controls how tumor cells acquire the energy necessary for movement, invasion and metastasis. this protein pathway was previously only observed in neurons and represents a potential therapeutic target for several types of cancer.
December 19, 2016
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NIH Researchers develop Technology Which Assists in Identification and Destruction of Cancer Cells
NIH-funded researchers have developed an innovative technology that can identify and assist the destruction of cancer cells in mice, causing no harm to the surrounding healthy tissue. a treatment by making use of this technology in humans could decrease the rate of cancer reappearance or metastasis.
July 8, 2016
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Nobel Prize in Physiology or Medicine 2016 Goes to Dr. Yoshinori Ohsumi for Discoveries of Mechanisms of Autophagy
We'd like to congratulate Yoshinori Ohsumi for winning the Nobel Prize in Physiology or Medicine 2016. Dr. Ohsumi discovered and gave us an understanding of the process of autophagy, which is how cells dispose of and recycle material from the cytoplasm. this process turned out to be more important than originally thought, playing a role in a wide variety of mechanisms and helping the body adapt to changing conditions. the Nobel Assembly at Karolinska Intitutet in Sweden that gives out the annual prize has a great overview of autophagy and how Dr Ohsumi's efforts led to the fundamental discoveries that deserved such an esteemed award.
October 3, 2016
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Non-toxic Salmonella strain could be promising new treatment option for cancer
According to the Centers for Disease Control, 48 million Americans contract foodborne diseases annually, with Salmonella being the leading cause of illness. Salmonella has a unique characteristic that allows the bacteria to penetrate through cell barriers and replicate inside its host.
October 27, 2016
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Not all tumor cells are equal
Scientists find that colorectal tumors present epigenetic heterogeneity relates to the clinical course of the disease
August 18, 2016
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Not such a 'simple' sugar: Glucose may be important in the fight against cancer
Scientists have just discovered that glucose, the most important fuel used in our bodies, also plays a vital role in the immune response. Targeting glucose-controlled systems in the body thus offers an exciting new option for regulating this response.
May 30, 2017
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Novel gene editing approach to cancer treatment shows promise in mice
New CRISPR-based gene therapy effectively targets cancer-causing 'fusion genes' and improves survival in mouse models of aggressive cancers, researchers report.
May 1, 2017
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Novel imaging technique protects healthy tissues during cryotherapy of cancer lesions
A solution to a major challenge in using minimally invasive cryotherapy to target and kill cancer cells with freezing temperatures while protecting adjacent healthy tissues has been reported by a research team in Texas in an article published this week in the Journal of Biomedical Optics. the journal is published by SPIE, the international society for optics and photonics.
November 10, 2016
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Novel label-free microscopy enables dynamic, high-resolution imaging of cell interactions
Researchers have invented a novel live-cell imaging method that could someday help biologists better understand how stem cells transform into specialized cells and how diseases like cancer spread. the Photonic Crystal Enhanced Microscope (PCEM) is capable of monitoring and quantitatively measuring cell adhesion, a critical process involved cell migration, cell differentiation, cell division, and cell death.
December 6, 2016
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Novel scaffolds may open new avenues in stem and cancer cell manipulation
A discovery in the field of biomaterials may open new frontiers in stem and cancer cell manipulation and associated advanced therapy development. Novel scaffolds are shown enabling cells to behave in a different but controlled way in vitro due to the presence of aligned, self-assembled ceramic nanofibers of an ultra-high anisotropy ratio augmented into graphene shells.
August 23, 2016
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Novel, non-invasive cancer therapy using targeted single-walled carbon nanotubes
A staggering 1.7 million persons in the United States will be diagnosed with cancer in 2016, with 600,000 cases ending in death. University of Oklahoma researchers have collaborated to design a novel, non-invasive cancer therapy that could eliminate tumors without affecting the healthy cells in the body.
October 18, 2016
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NYU dentists receive grant to test whether non-viral gene delivery can effectively treat oral cancer pain
The National Institute of Dental and Craniofacial Research, part of the National Institutes of Health, has awarded Drs. Brian Schmidt and Seiichi Yamano a $1.2M grant to test whether their non-viral gene delivery method can effectively and safely treat oral cancer pain.
June 28, 2016
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Misc. - O

On-off layer-by-layer nanoassemblies for oral cancer therapy
Oral cancer represents one of the most dreadful killer diseases globally. Researchers at Indian Institute of Technology Bombay, India have developed nano-sized layer by layer (LbL) assembled polyelectrolytes onto calcium carbonate particles to deliver small molecule tyrosine kinase inhibitors to human oral cancer cells.
July 27, 2016
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Oncologist outlines lack of cancer and psychiatric care in rural America
Jennifer Lycette, M.D., understands the importance of treating patients with cancer at home in their in rural communities. It allows them to spend more time with their families and to focus on their treatment and recovery, not traveling.
December 9, 2016
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One Dose of Radiation May Help Spine Pain in Cancer
Study suggests it works as well as a full week of treatments
June 2, 2017
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Online database aims to collect, organize research on cancer mutations
Goal is to help clinicians treat patients based on tumor genetics
January 30, 2017
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Open-source drug discovery a success
Researchers from around the world collaborate
July 28, 2016
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Optoacoustics May Allow Surgeons See Tumor Margins for Accurate Excisions
While doctors have gotten pretty good at finding and excising tumors, identifying whether they have been removed in their entirety remains a challenge. Histology slides are today's standard, but processing the tissue, freezing, slicing it, staining, imaging, and analysis take much too long. Patients are often sent home, only to find out later that a part of the tumor remains in their body.
May 19, 2017
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Organo-metal compound seen killing cancer cells from inside
Researchers have witnessed - for the first time - cancer cells being targeted and destroyed from the inside, by an organo-metal compound discovered by the University of Warwick.
February 13, 2017
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OSU scientists find way to fight solid tumors using new cancer-drug delivery system
A new cancer-drug delivery system shows the ability to exploit the oxygen-poor areas of solid tumors that make the growths resistant to standard chemotherapy and radiation treatment.
April 4, 2017
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Overcoming multidrug-resistant cancer with smart nanoparticles
Multidrug resistance is the mechanism by which many cancers develop resistance to chemotherapy drugs, resulting in minimal cell death and the expansion of drug-resistant tumors. to address the problem of resistance, researchers have developed nanoparticles that simultaneously deliver chemotherapy drugs to tumors and inhibit the MDR proteins that pump the therapeutic drugs out of the cell.
August 24, 2016
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Overexpression of nerve growth factor drives gastric tumorigenesis in mice
Gastric tumors are started by specialized cells in the stomach that signal nerves to make more acetylcholine, according to a study in mice. the multinational team of researchers who conducted the study also identified a substance called nerve growth factor that stimulates nerve development and, when blocked, inhibits stomach cancer development.
December 16, 2016
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Misc. - P

Pac-Man like protein which eats dead cells could help in the fight against cancer
A protein that causes cells to eat their dying neighbous, helping to prevent inflammation -- something that is vital in the fight to stop cancer spreading -- has been identified by researchers.
September 12, 2016
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Partners of cancer patients greatly appreciate web-based self-help intervention
Twenty to thirty percent of the partners of cancer patients suffer from psychological problems. this percentage is even higher if the patients in question are terminally ill. with this in mind, scientists from the University of Twente's Institute for Innovation and Governance Studies and VU University Medical Center have developed a web-based self-help intervention for people in this situation.
December 21, 2016
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Paxman integrates Titan 800-Series flowmeter into Scalp Cooling System to improve chemotherapy treatment
Titan Enterprises reports on how Paxman Coolers Ltd has enhanced their innovative Scalp Cooling System for chemotherapy treatment through integration of a Titan 800-Series flowmeter.
July 19, 2016
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Penn analysis finds genetic factors that could help identify men at increased risk for testicular cancer
An analysis of data from five major studies of testicular cancer has identified new genetic locations that could be susceptible to inherited testicular germ cell tumors. The findings, which researchers call a success story for genome mapping, could help doctors understand which men are at the highest risk of developing the disease and signal them to screen those patients.
June 12, 2017
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Penn researchers attempting to harness power of big data to help cancer patients avoid ER visits
What if doctors could look into a crystal ball and predict which of their patients might be at risk of getting sick enough to go to the emergency room? what if they could use that prediction to help patients get treatment more quickly, with less fear and uncertainty, and with a greater chance of returning home rather than being admitted to the hospital? for at least one group of patients, that's exactly what researchers at Penn Medicine are trying to do. But instead of peering into a crystal ball, they're attempting to harness the power of big data.
January 30, 2017
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Penn researchers uncover strategy to reverse effects of dyskeratosis congenita
Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure. Typically diagnosed in childhood, the disorder causes stem cells to fail, leading to significant problems including bone marrow failure, lung fibrosis, dyskeratosis of the skin and intestinal atrophy and inflammation. Patients are also at heightened risk of several types of cancer.
August 18, 2016
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Penn State researchers develop nanoprobes to rapidly isolate rare cancer markers
A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis. Researchers at Penn State have developed nanoprobes to rapidly isolate these rare markers, called extracellular vesicles (EVs), for potential development of precision cancer diagnoses and personalized anticancer treatments.
April 10, 2017
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Peptide mutants may help to identify vulnerability in tumor cells
Researchers have presented an algorithm to detect mutant proteins based on mass spectrometry data and the results of exome sequencing. Using this new approach, the scientists have discovered unique genome variants, some of which are linked to cancer development. Studying mutant peptides will help to detect weaknesses in tumor cells in search for more effective drug treatments.
August 29, 2016
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Person's risk factor status may help tailor surveillance program for melanomas, study suggests
The new study, published online today by JAMA Dermatology, identifies high risk patients who may benefit from tailored surveillance.
November 9, 2016
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Phase-contrast X-ray imaging could identify tumors earlier
What is phase-contrast X-ray imaging and how does it differ from conventional X-rays?
March 29, 2017
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Photoimmunotherapy may be promising treatment option to combat cancer
When Kerstin Stenson, MD, describes the innovative technique she is helping develop to fight cancer, it seems like she's describing a Tom Clancy military espionage novel.
November 15, 2016
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Physicist's DNA chip offers big possibilities in cell, cancer studies
A physicist has developed a novel technology that not only sheds light on basic cell biology, but also may aid in the development of more effective cancer treatments or early diagnosis of disease.
August 26, 2016
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Physicists receive three-year NSF grant to apply principles of soft-matter physics to cancer therapy
Three physicists in the College of Arts and Sciences are using a major grant to study the dynamics and interactions of cancer cells.
August 05, 2016
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Plant-made virus shells could deliver drugs directly to cancer cells
Viruses are extremely efficient at targeting and delivering cargo to cells. Researchers report they have harnessed this well-honed ability -- minus the part that makes us sick -- to develop virus-like nanoparticles to deliver drugs straight to affected cells. In lab tests, they show that one such particle can be produced in plants and it ferries small molecules to cancer cells.
February 15, 2017
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Poor overall environmental quality linked to elevated cancer rates
Nationwide, counties with the poorest quality across five domains -- air, water, land, the built environment and sociodemographic -- had the highest incidence of cancer, according to a new study.
May 8, 2017
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Portable smartphone laboratory detects cancer at once
Researchers have developed a low-cost, portable laboratory on a smartphone that can analyze several samples at once to catch a cancer biomarker, producing lab quality results.
October 18, 2016
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Possible treatment targets found for pre-malignant bone marrow disorders
Nature Immunology study uncovers key driver of MDS in blood stem cells
December 29, 2016
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Potential cancer treatment using microwaves and nanoparticles to target deep tumors
Physicists at the University of Texas at Arlington have shown that using microwaves to activate photosensitive nanoparticles produces tissue-heating effects that ultimately lead to cell death within solid tumors.
October 11, 2016
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Potential new cancer treatment activates cancer-engulfing cells
Macrophages are a type of white blood cell that can engulf and destroy cancer cells. a research group has discovered that by using an antibody for a particular protein found on macrophages, the macrophage is activated, and cancer cells are effectively eliminated. this discovery could lead to the development of new cancer treatments.
February 6, 2017
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Potential new drug class hits multiple cancer cell targets, boosting efficacy and safety
A potential new class of anti-cancer drugs inhibits two or more molecular targets at once, maximizing therapeutic efficiency and safety, report scientists.
February 1, 2017
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Potential therapy to prevent 'chemobrain' in cancer patients
A compound called 'KU-32' prevents cognitive decline in rats caused by chemotherapy treatment, research shows. KU-32 works by inducing the heat shock response, which protects cells and may counteract the damaging effects of hydrogen peroxide.
April 12, 2017
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Potential new treatment found for 'chemo brain'
Chemotherapy is the most commonly available form of cancer treatment, but its serious side effects are well-known. new research investigates the mechanism behind the cognitive impairment often associated with chemotherapy and offers new options for treating these adverse effects on the brain.
April 17, 2017
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Precision medicine trial first of its kind to show benefit to patients
A clinical trial for types of advanced cancer is the first of its kind to show that precision medicine -- or tailoring treatment for individual people -- can slow down the time it takes for a tumor to grow back, according to research.
September 23, 2016
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Pro-growth cancer signaling pathway could light up new avenues of treatments for solid tumors
Researchers from the University of Wisconsin School of Medicine and Public Health and Carbone Cancer Center have better defined a pro-growth signaling pathway common to many cancers that, when blocked, kills cancer cells but leaves healthy cells comparatively unharmed.
November 23, 2016
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Prolonged exposure to work-related stress linked to increased risk of cancers
For men, prolonged exposure to work-related stress has been linked to an increased likelihood of lung, colon, rectal, and stomach cancer and non-Hodgkin lymphoma. the findings are among the results obtained by researchers at INRS and Universite de Montreal who conducted the first study to assess the link between cancer and work-related stress perceived by men throughout their working life.
January 17, 2017
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Prolonged exposure to work-related stress thought to be related to certain cancers
First study on the link between cancer and work-related stress perceived by men throughout their working lifetime
January 17, 2017
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Promising approach for prognosis, treatment in mastocytosis
Systemic mastocytosis is a rare, incurable disease that affects approximately one in every 10,000 people. It is a haematological tumor disease, similar to leukemia, in which the bone marrow and other organs, such as the bowel, liver or spleen, are infiltrated by mast cells. In the animal model, researchers have now discovered a new prognostic and therapeutic approach that could at least help to prevent rapid progression of the disease.
December 13, 2016
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Proscia Pathology Cloud now with new Cancer Image Analysis Tools
Proscia, a digital pathology cloud system provider based in Baltimore, Maryland, is now offering a new set of cancer research tools on its platform. the Proscia Pathology Cloud allows users to harness the power of parallel computing to process large amounts of tissue samples in a browser-based interface that's easy to login to and use. Everything being online and in the cloud allows researchers to analyze and share whole slide imagery and corresponding information.
October 25, 2016
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Protein critical to toxoplasmosis regulation: CD4 T-Cell and Blimp-1
Researchers are finding a way to regulate chronic toxoplasmosis, one of the most common parasitic diseases worldwide. this research also has important implications for cancer.
August 1, 2016
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Protein that promotes 'cell-suicide' could revolutionize eye cancer treatment
New research has identified the role of a specific protein in the human body that can help prevent the survival and spread of eye cancer, by initiating cancer 'cell-suicide.'
December 6, 2016
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Proton Partners acquires Blue Phantom2 data acquisition system to support innovative cancer treatment
The Blue Phantom2 measures data with certified accuracy for commissioning and routine quality assurance ensuring accurate delivery of radiotherapy treatment
December 9, 2016
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Psychological intervention lowers survivors' fear of cancer recurrence
About 50 percent of all cancer survivors and 70 percent of young breast cancer survivors report moderate to high fear of recurrence. The fear can be so distressing that it negatively affects medical follow-up behavior, mood, relationships, work, goal setting, and quality of life. Yet, interventions to alleviate this fear are lacking.
June 5, 2017
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Psychological intervention reduces fear of recurrence in breast cancer survivors
About 50% of all cancer survivors and 70% of young breast cancer survivors report moderate to high fear of recurrence. The fear can be so distressing that it negatively affects medical follow-up behavior, mood, relationships, work, goal setting, and quality of life. Yet, interventions to alleviate this fear are lacking.
June 5, 2017
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Punching cancer with RNA knuckles
Researchers achieved an unexpected eye-popping reduction of ovarian cancer during a successful test of targeted nanohydrogel delivery in vivo in mice. Adding cisplatin eliminated or starkly diminished tumors, report investigators.
November 7, 2016
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Misc. - Q

Quadruple helix form of DNA may aid in the development of targeted cancer therapies
Scientists have identified where a four-stranded version of DNA exists within the genome of human cells, and suggest that it may hold a key to developing new, targeted therapies for cancer.
September 12, 2016
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Misc. - R

Raised blood platelet levels 'strong predictor' of cancer
Having a high blood platelet count is a strong predictor of cancer and should be urgently investigated to save lives, according to a large-scale study.
May 23, 2017
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Rapid capture of cancer markers with lipid nanoprobes will aid in diagnosis and treatment
A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis. Researchers at Penn State have developed nanoprobes to rapidly isolate these rare markers, called extracellular vesicles (EVs), for potential development of precision cancer diagnoses and personalized anticancer treatments.
April 10, 2017
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Random DNA copying 'mistakes' account for most cancer mutations, study finds
Johns Hopkins Kimmel Cancer Center scientists report data from a new study providing evidence that random, unpredictable DNA copying "mistakes" account for nearly two-thirds of the mutations that cause cancer. Their research is grounded on a novel mathematical model based on DNA sequencing and epidemiologic data from around the world.
March 24, 2017
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Random mutations play large role in cancer, study finds
Analysis suggests that cell division produces more malignancy-linked errors than environment, inheritance
March 23, 2017
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Reactive oxygen species: Fueling or putting the brakes on inflammation?
Reactive oxygen species (ROS) are important signalling molecules in an organism's regulation of metabolism and inflammation. Accumulation of ROS have been linked to neurodegeneration and cancer. Researchers in Sweden now reveal an unexpected function of ROS: they dampen a key inflammatory process and weaken the immune system's ability to combat pathogens such as those that cause pneumonia.
July 12, 2016
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Readers concerned about cancer's sugary disguise
A new wave of potential immune therapies aims to target the network of complex sugars that coat cancer cells, Esther Landhuis reported in "Cancer's sweet cloak'. some of these sugars, called sialic acids, help tumors hide from the immune system.
May 3, 2017
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Recycling approved drugs for cancer treatment
In recent years, it has become a medical trend to do research on well-known drugs, to discover unknown effects. this strategy is called repurposing. now researchers have found that a drug against kidney cancer can possibly fight several types of cancer.
September 29, 2016
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Recycling existing drugs may help fight several types of cancer
Researchers at the University of Bergen have discovered that a drug against kidney cancer possibly can fight several types of cancer.
September 29, 2016
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Red onions pack a cancer-fighting punch, study reveals
Researchers are the first to discover Ontario-grown red onions have the strongest cancer-fighting power
June 7, 2017
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Reducing the radioresistance of cancer
Some cancer cells are protected from radiation therapy through an interaction of interleukin-6 with the Nrf2-antioxidant pathway, researchers have found. the discovery is believed to improve methods of increasing cancer's radiosensitivity.
January 13, 2017
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Refined method offers new piece in the cancer puzzle
A special spectrometry method that is normally used in analyses of computer chips, lacquers and metals has been further developed at the University of Gothenburg so that it can help researchers better detect harmful cells in the body.
February 8, 2017
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Refined method offers new piece in the cancer puzzle
A special spectrometry method that is normally used in analyses of computer chips, lacquers and metals has been further developed so that it can help researchers better detect harmful cells in the body.
February 8, 2017
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Reprogrammed blood vessels promote cancer spread
Tumor cells use the bloodstream to spread in the body. to reach the blood, they first have to pass the wall of the vessel. Scientists have now identified a trick that the cancer cells use: they activate a cellular signal in the vessel lining cells. this makes the passage easier and promotes metastasis. In experiments with mice, the researchers were able to block this process using antibodies.
March 3, 2017
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Research aids discovery of genetic immune disorder
Immune molecule deficiency increases patients' risk of Epstein-Barr virus and EBV-related cancer
December 23, 2016
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Research aims to understand how cell designs length, pattern of heparan sulphate chains
Heparan sulphate occurs as carbohydrate chains which are very important for human body cells both for normal foetal development and during the course of various diseases. all new molecular knowledge concerning these chains is therefore important. Researchers can now show that the same enzyme which determines the charge pattern of the chains also determines their length.
September 2, 2016
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Research findings may provide new treatment for prevention of cancer metastasis
Breast cancer metastasis, the process by which cancer spreads, may be prevented through the new use of a class of drugs already approved by the U.S. Food and Drug Administration. Mayo Clinic researchers have identified that a key drug target, CDK4/6, regulates a cancer metastasis protein, SNAIL, and drugs that inhibit CDK 4/6 could prevent the spread of triple-negative breast cancer.
January 9, 2017
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Research findings show effective way to harness anti-tumor potential of macrophages in cancer therapy
for all the success of a new generation of immunotherapies for cancer, they often leave an entire branch of the immune system's disease-fighting forces untapped. Such therapies act on the adaptive immune system, the ranks of specialized cells that mount precision attacks on foreign and diseased cells. the other arm of the immune system, known as innate immunity, may not be merely idle during this battle, but may actually abet tumor growth.
March 9, 2017
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Research finds differences in cell migration between normal and malignant tumor cells
What makes cancer so deadly is its ability to move . the better that doctors can keep tumors contained and protect unaffected organs in the body, the less lethal a cancer will be.
December 21, 2016
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Research identifies potential treatment target for chemoresistant cancer cells
A team of researchers has discovered that chemoresistant lung cancer cells suppress immune functions and strengthen resistance to chemotherapy by producing interleukin-34 (IL-34)–a type of cytokine.
October 3, 2016
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Research into Nanoparticle Activation Could Potentially Transform Cancer Treatment
Physicists at the University of Texas at Arlington have shown that using microwaves to activate photosensitive nanoparticles produces tissue-heating effects that ultimately lead to cell death within solid tumors.
October 12, 2016
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Research opens up new ways to detect, inhibit cancer spread
Clusters of circulating cells commonly found in the blood of cancer patients have long been the subject of research on cancer. These clusters have been regarded for more than 50 years as malignant cells that have broken off from the primary tumor, spreading cancer to other parts of the body.
July 8, 2016
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Research reveals cancer pathway to spreading through the body
Scientists show role oxygen plays in cell movement
August 02, 2016
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Research sheds new light on key drivers of cancer metastasis
Latest research from new Zealand's University of Otago is shedding new light on why and how cancer cells spread from primary tumours to other parts of the body. this phenomenon - known as metastasis - causes about 90 per cent of all cancer deaths.
December 21, 2016
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Research will shift how cancer diversity and resistance are understood, studied
Circular DNA, once thought to be rare in tumor cells, is actually very common and seems to play a fundamental role in tumor evolution, say researchers.
February 8, 2017
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Researcher receives federal grant to advance study of tumor nanoimmunology
Julia Ljubimova, MD, PhD, director of theNanomedicine Research Center in theCedars-Sinai Department of Neurosurgery, has received a $2.8 million federal grant to advance her research of tumor nanoimmunology to treat cancers of the brain, breast, lung and other organs.
June 29, 2016
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Researcher to examine if music intervention can alleviate distress in young cancer patients and parents
An Indiana University School of Nursing researcher has been awarded $1.4 million to determine if a music therapy intervention can be used to manage acute distress in young cancer patients ages 3 to 8 and their parents.
November 22, 2016
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Researchers awarded grant to develop safer cancer therapies for children
Two Case Western Reserve University School of Medicine researchers are receiving new funding from California-based St. Baldrick's Foundation for promising childhood cancer research.
October 5, 2016
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Researchers build liquid biopsy chip that detects metastatic cancer cells in blood
More effective than existing microfluidic devices, the breakthrough technology
December 14, 2016
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Researchers chart global genetic interaction networks in human cancer cells
Genetic networks have been identified in human cells, say researchers, noting that the study has also found potential targets for cancer therapy.
February 2, 2017
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Researchers create anticancer nanomaterials by simulating underwater volcanic conditions
Researchers at Aalto University, Finland, have developed anticancer nanomaterials by simulating the volcano-induced dynamic chemistry of the deep ocean. the novel method enables making nanoclusters of zinc peroxide in an environmentally friendly manner, without the use of additional chemicals. the as-synthesised zinc peroxide nanoparticles can be used as a tool for cancer therapy and against other complicated diseases.
May 12, 2017
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Researchers deliver first nanotherapeutics to tumor
For the first time, WSU researchers have demonstrated a way to deliver a drug to a tumor by attaching it to a blood cell. the innovation could let doctors target tumors with anticancer drugs that might otherwise damage healthy tissues.
May 15, 2017
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Researchers develop hybrid nanomaterial for destruction of cancer cells
Most tumors contain regions of low oxygen concentration where cancer therapies based on the action of reactive oxygen species are ineffective. Now, American scientists have developed a hybrid nanomaterial that releases a free-radical-generating prodrug inside tumor cells upon thermal activation. as they report in the journal Angewandte Chemie, the free radicals destroy the cell components even in oxygen-depleted conditions, causing apoptosis. Delivery, release, and action of the hybrid material can be precisely controlled.
May 4, 2017
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Researchers develop innovative nanobiodevice that enables rapid detection of cancer biomarker
Like DNA, ribonucleic acid (RNA) is a type of polymeric biomolecule essential for life, playing important roles in gene processing. Short lengths of RNA called microRNA are more stable than longer RNA chains, and are found in common bodily fluids. the level of microRNA in bodily fluids is strongly correlated with the presence and advance of cancer.
March 8, 2017
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Researchers develop method to speed up detection of infectious diseases, cancer
A team of UCLA researchers has found a way to speed and simplify the detection of proteins in blood and plasma opening up the potential for diagnosing the early presence of infectious diseases or cancer during a doctor's office visit. the new test takes about 10 minutes as opposed to two to four hours for current state-of-the-art tests.
August 29, 2016
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Researchers develop new nanorobotic agents to deliver drugs by targeting cancerous tumours
Researchers from Polytechnique Montreal, Universite de Montreal and McGill University have just achieved a spectacular breakthrough in cancer research. they have developed new nanorobotic agents capable of navigating through the bloodstream to administer a drug with precision by specifically targeting the active cancerous cells of tumours.
August 16, 2016
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Researchers develop new tumor-shrinking nanoparticle to fight cancer, prevent recurrence
A Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease. In the study, published today in Nature Nanotechnology ("Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy"), mice that received an injection with the nanoparticle showed a 70 to 80 percent reduction in tumor size. Most significantly, mice treated with these nanoparticles showed resistance to future tumor recurrence, even when exposed to cancer cells a month later.
May 1, 2017
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Researchers develop simple, flexible technique for early cancer diagnosis
Earlier discovery of cancer and greater precision in the treatment process are the objectives of a new method developed by researchers at Sahlgrenska Academy and Boston University. Investments are now being made to roll out this innovation across healthcare and broaden the scope of the research in this field.
May 22, 2017
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Researchers discover how primary tumors can program cancer cells that spread to become dormant, resist cancer treatment
In a first of its kind study, researchers have discovered the conditions by which specific signals in primary tumors of head and neck and breast cancers, pre-program cancer cells to become dormant and evade chemotherapy after spreading. Their findings could lead to new drug development, treatment options and transform the way doctors care for cancer patients to treat metastatic disease.
January 26, 2017
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Researchers discover intestinal quiescent stem cells that are resistant to chemotherapy
The intestine has a high rate of cellular regeneration due to the wear and tear originated by its function degrading and absorbing nutrients and eliminating waste. the entire cell wall is renewed once a week approximately. this explains why the intestine holds a large number of stem cells in constant division, thereby producing new cell populations of the various types present in this organ.
March 10, 2017
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Researchers discover new genes with potential to improve adoptive T cell therapy
A Yale Cancer Center research team has identified that two genes, NR4A1 and ABC transporters, mark a distinct subset of quiescent T cells within human tissues, and have developed methods to mobilize them into circulation for potential application in adoptive T cell therapy of cancer.
September 15, 2016
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Researchers discover potential novel strategy for improving immunotherapy against cancer
Researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have discovered a potential novel strategy for improving drugs that unleash the immune system against cancer -- by binding two compounds to a nanoparticle.
April 3, 2017
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Researchers discover unexpected link between brain development and tumor invasion
Researchers from Turku Centre for Biotechnology have observed that a protein called SHANK prevents the spread of breast cancer cells to the surrounding tissue. the SHANK protein has been previously studied only in the central nervous system, and it is known that its absence or gene mutations are related to autism.
March 9, 2017
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Researchers explain why explain why some tumors recur after immunotherapy
Immunotherapy is a new and highly promising form of treatment for cancer. In many patients, however, tumors recur after immunotherapy. In the latest issue of the Journal of Experimental Medicine, the members of a research team from the Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC), the Berlin Institute of Health (BIH), and Charite - Universitatsmedizin Berlin explain why some tumors recur and how this can be prevented. the findings will aid the selection of suitable target points for immunotherapy.
October 7, 2016
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Researchers find another immune system link science said didn't exist
Unexpected connection likely sabotaging vaccines designed to treat cancer
March 23, 2017
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Researchers find new path to stop metastatic growth of cancer
Investigators from the Research Institute of the McGill University Health Centre, and the Institute of Cancer Research, London, have discovered that some cancer cells can draw blood from existing mature blood vessels allowing them to continue to spread.
October 18, 2016
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Researchers find unforeseen increase in smoking-related mortality risk among East German women
The researchers found that East German women are running the risk of an unforeseen increase in deaths through smoking. According to the calculations, rates for deaths from lung cancer, which is a very strong indicator for the effect of smoking, will rise continuously for East German women aged 50 and older.
May 10, 2017
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Researchers have developed a new class of artificial proteins
In the journal, Nature Communications, a team of Danish researchers reports that they have developed a new class of artificial proteins. In the long term, the results could lead to better treatment of cancer and diabetes.
August 09, 2016
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Researchers identify mechanisms triggering hypergammaglobulinemia
Some autoimmune diseases and persistent infections are characterized by high levels of antibodies in the blood. But what are the causes of this hypergammaglobulinemia? a team headed by INRS's Professor Simona Stager has successfully identified the mechanisms triggering the phenomenon. for the first time ever, she has established a link between B-cell activation by a protein--type 1 interferon--and unusually high antibody levels.
July 12, 2016
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Researchers identify promising prospect for new medications to fight against H. pylori
There is a strong suspicion that Helicobacter pylori is linked to the development of stomach cancer. now an international team of researchers led by Prof. Donald R. Ronning (University of Toledo, USA) has used neutrons to unlock the secret to the functionality of an important enzyme in the bacterium's metabolism.
December 21, 2016
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Researchers identify set of genes that play vital role in early human development
Oxford University researchers are closer to solving a decade-old mystery after discovering that a set of genes they are studying play a key role in early human development.
June 29, 2016
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Researchers propose new approach to target chemotherapy medications specifically to sarcomas
Sarcoma is an aggressive form of cancer responsible for up to 20 percent of childhood cancers. Tumors often first appear in the extremities and the abdomen. Surgery is a primary treatment, but it often is combined with chemotherapy.
July 15, 2016
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Researchers question process for reviewing coverage of 'off label' cancer drug use
Physician-researchers have raised concerns that there are inconsistencies between the five reference guides, or compendia, that the Centers for Medicare and Medicaid Services uses to determine which drugs it will reimburse for off-label uses in cancer care.
August 25, 2016
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Researchers reveal first three-dimensional molecular map of protein linked to many cancers
Walter and Eliza Hall Institute researchers have revealed for the first time the three-dimensional molecular 'map' of a protein that has been pinpointed as a driver of many types of cancers.
August 19, 2016
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Researchers reveal how cancer cells cope with genetic chaos
Scientists have uncovered how tumors are able to grow despite significant damage to the structure and number of their chromosomes, the storage units of DNA.
January 9, 2017
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Researchers show how circadian 'clock' may influence cancer pathway
A new study describes an unexpected role for proteins involved with our daily "circadian" clocks in influencing cancer growth.
November 16, 2016
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Researchers show porous silicon nanoparticles could be harmless to diagnose and treat cancer
The Lomonosov Moscow State University researchers in collaboration with their German colleagues have succeeded in proving that silicon nanoparticles can be applied to diagnose and cure cancer. for the first time the ability of particles to penetrate into the diseased cells effectively and dissolve completely after delivering the drug was shown.
July 21, 2016
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Researchers study patients' genetic and susceptibility risk factors for lymphedema
Genetic variations may be one of the important factors that influence breast cancer survivors' responses to the inflammatory processes and vulnerability to lymphedema.
February 8, 2017
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Researchers take important step forward in disabling cancer cells' defences
Recent study out of the University of Ottawa opens door for new disease therapies in cancer, ALS, Fragile X Syndrome and others.
March 10, 2017
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Researchers uncover global regulator that 'switches on' silent biosynthetic gene clusters
Bacteria have supplied some of today's most indispensable anti-cancer and anti-bacterial drugs. Yet these compounds comprise only a fraction of their possible offerings. Now, researchers have found a way to unleash their full potential as natural product dispensers.
April 13, 2017
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Researchers uncover protein-based 'cancer signature'
A research team has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature. this "cancer signature" could potentially be used to predict the progression of the disease.
December 5, 2016
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Researchers uncover protein-based 'cancer signature'
A research team at the University of Basel's Biozentrum has investigated the expression of ribosomal proteins in a wide range of human tissues including tumors and discovered a cancer type specific signature. as the researchers report in Genome Biology ("Patterns of ribosomal protein expression specify normal and malignant human cells") this "cancer signature" could potentially be used to predict the progression of the disease.
December 5, 2016
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Researchers underscore importance of immune-based prevention to conquer cancer
In a Perspective piece published this week in PNAS, cancer researchers from across the country, including faculty at University of California San Diego School of Medicine and Moores Cancer Center, write that a greater emphasis on immune-based prevention should be central to new efforts like the federal Cancer Moonshot program, headed by Vice President Joe Biden.
September 19, 2016
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Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood
A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.
December 6, 2016
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Resistance to targeted therapy in mantle cell lymphoma
A team of cancer researchers have published research looking at the underlying mechanisms of resistance to the drug, Ibrutinib, which is used to treat patients with mantle cell lymphoma.
June 14, 2017
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Retinoic acid may significantly prevent lymphedema development, experimental model suggests
Using newly updated mouse models, researchers demonstrated the impactful preventive properties of 9-cis retinoic acid against lymphedema. Currently, there is no cure for lymphedema, a swelling of the extremities that most commonly occurs after treatment for cancer.
September 16, 2016
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Risk of skin cancer doesn't deter most college students who tan indoors, study shows
White female college students in Indiana who tan indoors know they are placing themselves at risk of skin cancer and premature skin aging, but most continue to tan indoors anyway, according to a study.
January 10, 2017
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Roadmap to more personalized cancer treatment
People with advanced head and neck squamous cell carcinoma and the KRAS-variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation, research has found.
December 22, 2016
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Robert Herjavec on Improving Cancer Care, Healthcare IT Security, Innovation, and Investment
Last weekend we attended the Stanford Medicine X conference that brought together a variety of people involved in every aspect of health care. Even a few investors were present, but none more famous than Robert Herjavec. He's the "nice guy" on Shark Tank, the TV show where entrepreneurs pitch their businesses to wealthy investors.
September 23, 2016
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Rotating Magnetic Nanoparticles Could Mechanically Destroy Cancer Cells
An international team in which a UPM researcher is involved has shown that it is possible to mechanically destroy cancer cells by rotating magnetic nanoparticles attached to them in elongated aggregates.
June 14, 2017
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Misc. - S

Safe Delivery of Therapeutic Genes by DNA Barcoding
Researchers used small snippets of DNA as barcodes to develop a new technique for rapidly screening the capability of nanoparticles to selectively deliver therapeutic genes to particular organs of the body. this new technique succeeded in accelerating the development and use of gene therapies for Parkinson™ disease, cancer and heart disease.
February 8, 2017
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Salk professor receives inaugural Sjg Prize for groundbreaking cancer research
Salk Professor Tony Hunter, who holds an American Cancer Society Professorship, has been awarded $500,000 as part of the $1 million Royal Swedish Academy of Sciences' inaugural Sjg Prize for Cancer Research for "groundbreaking studies of cellular processes that have led to the development of new and effective cancer drugs."
February 14, 2017
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Salmonella protein reduces drug resistance in tumors
Researchers develop a Salmonella 'nanobug' mimic to boost drug efficacy in cancer chemotherapeutics
July 25, 2016
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Sanger Institute partners with St. Jude to support discovery, understanding of genetic mutations in paediatric cancers
The Wellcome Trust Sanger Institute is combining the power of COSMIC, its large-scale cancer genetics database, with ProteinPaint data mining and visualization system at St. Jude Children's Research Hospital in Memphis TN, to support the discovery and understanding of genetic mutations in paediatric cancers.
September 21, 2016
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Screening the dark genome for disease
Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. the technique could revolutionize modern medicine's understanding of the genetically inherited risks of developing heart disease, diabetes, cancer, neurological disorders and others, and lead to new treatments.
April 3, 2017
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Scientists are using gene editing to try to slow cancer growth
With more research, CRISPR could give us a new cancer treatment.
May 25, 2017
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Scientists build a better cancer drug to pass through blood-brain barrier
In efforts to develop new treatments for brain cancer, scientists report they have altered the structure of an experimental drug that seems to enhance its ability to slip through the mostly impermeable blood-brain barrier.
October 20, 2016
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Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases
Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body.
August 11, 2016
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Scientists create 'immunoswitch' particles that slow cancer growth in test animals
Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells' defensive properties while switching on a robust anticancer immune response in mice. Experiments with the tiny, double-duty "immunoswitch" found it able to dramatically slow the growth of mouse melanoma and colon cancer and even eradicate tumors in test animals, the researchers report.
June 8, 2017
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Scientists develop a cancer-detecting smartphone add-on that's up to 99% accurate
Researchers from Washington State University have come up with a diagnostic rig that can use a smartphone, a prism, and an ELISA plate to detect cancer. In the controlled settings of their lab, with the high-purity reagents they had to work with, the researchers were able to detect the cancer marker interleukin-6 (IL-6) with 99% accuracy.
November 2, 2016
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Scientists develop computational method to map cancer progression
A team of scientists has developed a computational method to map cancer progression, an advance that offers new insights into the factors that spur this affliction as well as new ways of selecting effective therapies.
June 28, 2016
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Scientists develop new Microfluidic Device to Test Effects of Electric Fields on Cancer Cells
Researchers at MIT's research center in Singapore have developed a new microfluidic device that tests the effects of electric fields on cancer cells. they observed that a range of low-intensity, middle-frequency electric fields effectively stopped breast and lung cancer cells from growing and spreading, while having no adverse effect on neighboring healthy cells.
July 6, 2016
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Scientists develop novel chemical 'dye' to improve liver cancer imaging
A new nanodiamond-based dual-mode contrast agent provides clearer and more accurate images of liver tumors at lower dosages, report researchers.
May 2, 2017
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Scientists develop novel multifunctional platform to integrate imaging and photo-induced cancer therapy
Physicists from the University of Texas at Arlington are leading a multidisciplinary project with the University of Texas Southwestern Medical Center in Dallas and the University of Texas MD Anderson Cancer Center in Houston to develop a new multifunctional platform that can integrate imaging and photo-induced cancer therapy in a single, portable device.
August 05, 2016
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Scientists developing magnetic stem cells to fight cancer
Scientists from the Tomsk Polytechnic University's Laboratory of Novel Dosage are developing a technology to control mesenchymal stem cells of patients. the technology will allow treating cancer more effective. to fight cancer cells the scientists suggest using the patient's own magnet controlled cells. Native body cells won't be rejected by its immune system and can deliver medication directly into the center of the disease.
December 29, 2016
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Scientists discover a molecular motor has a 'gear' for directional switching
A study published today offers a new understanding of the complex cellular machinery that animal and fungi cells use to ensure normal cell division, and scientists say it could one day lead to new treatment approaches for certain types of cancers.
January 4, 2017
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Scientists discover a molecular motor has a 'gear' for directional switching
A new study offers a new understanding of the complex cellular machinery that animal and fungi cells use to ensure normal cell division, and scientists say it could one day lead to new treatment approaches for certain types of cancers.
January 4, 2017
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Scientists discover mechanism that causes cancer cells to self-destruct
Modifying specific proteins during cancer cell division unleashes a natural killing mechanism
March 27, 2017
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Scientists Discover Nanoparticle Capable of Killing Cancer Cells
Cornell dots or C dots are nanoparticles that are emerging as promising therapeutic tools to detect and treat cancer.
September 29, 2016
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Scientists discover new natural source of potent anti-cancer drugs
An efficient process to rapidly discover new "enediyne natural products" from soil microbes has now been developed that could be further developed into extremely potent anticancer drugs, researchers report.
December 20, 2016
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Scientists discover potential mechanism for early detection, better treatment of gastric cancer
Changes in ribonucleic acid (RNA) sequences play a major role in the development of gastric cancer, researchers have discovered. Further research into this novel driving force for gastric cancer may potentially contribute towards early detection of gastric cancer and better treatment of the deadly disease.
September 13, 2016
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Scientists discover protein that helps provide better vaccination response
Researchers have discovered a protein they believe would help make vaccinations more effective and provide protection from other diseases such as cancer.
April 7, 2017
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Scientists discover that foot callouses can be linked to oesophageal cancer
Scientists from Queen Mary University of London have discovered that foot callouses/keratoderma (thickened skin) can be linked to cancer of the oesophagus (gullet), a disease which affects more than 8000 people in the UK each year.
February 1, 2017
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Scientists discover way of improving immune system's memory to recognise and fight cancers
Scientists from the University of Southampton have discovered an important way that the immune system can learn to recognise and fight cancers.
February 1, 2017
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Scientists establish process for identifying biomarkers for cancer diagnosis
Scientists at Ruhr-Universität Bochum have established a process for identifying biomarkers for the diagnosis of different types of cancer. with the aid of a specific type of infrared (IR) spectroscopy, the researchers applied an automated and label-free approach to detect tumour tissue in a biopsy or tissue sample.
April 3, 2017
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Scientists explain concept of combining NO gas therapy with starvation of tumor cells for nanomedical treatment
Biocompatible nanocapsules, loaded with an amino acid and equipped with an enzyme now combine two anti-tumor strategies into a synergistic treatment concept. Researchers hope this increases effectiveness and decreases side effects.
December 14, 2016
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Scientists explain how engineered anthrax toxin proteins could help eliminate cancerous tumors
Scientists from the National Institute of Allergy and Infectious Diseases, the National Institute of Dental and Craniofacial Research, and the National Heart, Lung and Blood Institute, all parts of the National Institutes of Health, describe how combining engineered anthrax toxin proteins and existing chemotherapy drugs could potentially yield a therapy to reduce or eliminate cancerous tumors.
June 28, 2016
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Scientists find key cues to regulate bone-building cells
The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as scientists have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.
February 2, 2017
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Scientists find novel way for earlier detection of deadly Merkel cell carcinoma
Scientists have found a way to detect earlier if a deadly cancer, Merkel cell carcinoma (MCC), is recurring in patients, according to a paper to be published 11 a.m. Eastern time, Dec. 7, in the journal Cancer.
December 6, 2016
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Scientists find way to use CRISPR/Cas9 technology to diagnose and inactivate cancer mutations
As for many other biomedical and biotechnology disciplines, the genome scissor "CRISPR/Cas9" also opens up completely new possibilities for cancer research. Scientists of the National Center for Tumor Disease (NCT), the German Consortium for Translational Cancer Research (DKTK) and the Medical Faculty of the TU Dresden have shown that mutations that act as cancer drivers can be targeted and repaired.
August 31, 2016
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Scientists identify eight cancer types linked to excess weight and obesity
There's yet another reason to maintain a healthy weight as we age. An international team of researchers has identified eight additional types of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (a type of brain tumor), thyroid cancer and the blood cancer multiple myeloma.
August 25, 2016
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Scientists identify new way to accelerate ion beams for improving cancer treatment
A group of researchers at Chalmers University of Technology has discovered a completely new way of using lasers to accelerate ion beams. In time, the new technique could possibly give more people access to advanced cancer treatment.
September 7, 2016
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Scientists identify new way to block action of genetic mutations found in most cancers
Researchers at the University of Illinois at Chicago have identified a new way to block the action of genetic mutations found in nearly 30 percent of all cancers.
November 7, 2016
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Scientists identify RIOK1 enzyme as new target for cancer therapy
Dr. Florian Weinberg, from Prof. Dr. Tilman Brummer's research group at the Institute of Molecular Medicine and Cell Research (IMMZ) of the University of Freiburg, joined forces with scientists from the Departments of Clinical Pathology and Medicine I of the University Medical Centre Freiburg and the Kinghorn Cancer Centre/Garvan Insitute in Australia in an international team that has identified a new target for cancer therapy.
May 5, 2017
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Scientists investigate cancer radiotherapy to make improvements
When tumors are treated with radiotherapy, the benefits can be hijacked by the treatment's counteraction to trigger inflammation and dampen the body's immune response, new research shows.
December 14, 2016
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Scientists modify structure of cancer drug to enhance ability to pass through blood-brain barrier
In efforts to develop new treatments for brain cancer, scientists from Johns Hopkins Drug Discovery and the Kimmel Cancer Center's Bloomberg~Kimmel Institute for Cancer Immunotherapy report they have altered the structure of an experimental drug that seems to enhance its ability to slip through the mostly impermeable blood-brain barrier.
October 20, 2016
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Scientists produce world's first CT images of biological tissue using protons
An international team of scientists has produced the world's first computerized tomography (CT) images of biological tissue using protons - a momentous step towards improving the quality and feasibility of Proton Therapy for cancer sufferers around the world.
May 11, 2017
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Scientists provide new insights into workings of cancer-linked potassium channel
Most cells in the body carry on their surface tiny pores through which potassium ions travel. In controlling the flow of these positively charged ions, the channel helps the cell maintain its electrical balance.
August 11, 2016
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Scientists reveal potential way of boosting immune system's memory to fight cancer
Scientists have discovered an important way that the immune system can learn to recognize and fight cancers, outlines a new report.
February 1, 2017
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Scientists synthesize and evaluate mono/di-halogenated coumarins for anticancer activity
Throughout the world, many medicinal compounds are being discovered. Scientists have learnt to modify the chemical structures of active compounds so that they can improved therapeutic activity and reduced the toxicity. In view of the established low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of coumarins, it appears prudent to evaluate their properties and applications further.
January 30, 2017
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Scientists uncover how tumor cells can switch disguises to spread easily around the body
Scientists have uncovered how tumor cells in aggressive uterine cancer can switch disguises and spread so quickly to other parts of the body. In a study published in Neoplasia, researchers at the Washington University School of Medicine created a map showing which genes were switched on and off in different parts of the tumor, providing a "signature" of these switches throughout the genome.
March 30, 2017
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Scientists unravel mechanism fueling growth of aggressive Rhabdoid tumors
Rhabdoid tumors are among the most recalcitrant childhood cancers, and scientists have long sought ways to understand what drives their resilience and makes them impervious to treatment. now researchers have uncovered a molecular chain of events that interferes with a key mechanism that regulates cell behavior and controls tumor formation.
December 13, 2016
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Scientists use male mice model to study how genes affect sequencing of vocal sounds
There's a particular order to the sounds of the ultrasonic song a male mouse performs to impress his potential mate.
October 20, 2016
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Scientists use molecular bait strategy to capture and isolate cancer-prone protein
IBS researchers modified an anti-cancer drug to capture and purify a cancer-prone protein
March 2, 2017
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Scientists use tumor-derived dendritic cells to slow tumor growth
In the human body, so-called dendritic cells are responsible for activating our immune system. While researchers previously believed that tumors could repress these dendritic cells -- blocking an adequate natural cancer defense mechanism -- a new study has painted a more positive picture.
January 25, 2017
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Scientists want to borrow power from your phone to cure cancer
A team in Japan has used the processing power of citizens' phones and computers to find a cure for neuroblastoma. Now, it's focusing on childhood cancer.
March 9, 2017
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Scripps collaborates with MD Anderson for clinically integrated cancer care program
Scripps Health and the University of Texas MD Anderson Cancer Center have reached a partnership agreement to create Scripps MD Anderson Cancer Center, a comprehensive and clinically integrated cancer care program in San Diego that will provide adult cancer patients greater access to the most advanced oncology care available throughout Southern California.
August 29, 2016
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Sean Parker's cancer institute may have found a blood test to see if patients will respond to treatment
Scientists in collaboration with tech billionaire Sean Parker's Institute for Cancer Immunotherapy may have found a way to predict whether melanoma patients will respond to treatments that target the PD-1 (programmed cell death protein) pathway in tumors through a simple blood test, according to a paper in the scientific journal Nature.
April 10, 2017
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Second cancers are far deadlier in younger people than older adults
Second cancers in children and adolescents and young adults (AYA) are far deadlier than they are in older adults and may partially account for the relatively poor outcomes of cancer patients ages 15-39 overall, a new study by UC Davis researchers has found.
April 20, 2017
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Selective manipulation of enzyme can stop cancer cachexia
Healthy fat tissue is essential for extended survival in the event of tumor-induced wasting syndrome (cachexia). In Nature Medicine, researchers at Helmholtz Zentrum Munchen show that selective manipulation of an enzyme can stop unwanted metabolic processes.
August 30, 2016
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Selenium status influence cancer risk
Researchers are examining underlying relationships
August 31, 2016
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Selenium status linked to cancer risk
As a nutritional trace element, selenium forms an essential part of our diet. In collaboration with the International Agency for Research on Cancer, researchers from Charite - Universitatsmedizin Berlin have been able to show that high blood selenium levels are associated with a decreased risk of developing liver cancer. In addition to other risk factors, the study also examines in how far selenium levels may influence the development of other types of cancer.
August 31, 2016
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Seven substances added to 14th Report on Carcinogens
Five viruses, a chemical, and a metallic element listed in new HHS report.
November 3, 2016
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Short-term fasting during chemotherapy may counteract side effects of common cancer drugs
A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research from the University of Southern California.
April 4, 2017
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Significant expansion of data available in the Genomic Data Commons
Cancer genomic profile information from 18,000 adult cancer patients will be added to the database.
June 29, 2016
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Single cells lined up like ducks in a row
The higher the concentration of tumor cells in the bloodstream, the greater the risk of metastasis. The number of circulating tumor cells indicates how well a patient is responding to therapy. Researchers have developed a new microhole chip that enables cells to be identified and characterized reliably within minutes.
June 7, 2017
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Silicon Nanoparticle Heater and Thermometer United to Fight Cancer
A Team of Russian Physicists from ITMO University have discovered that spherical silicon nanoparticles can be effectively heated up and concurrently produce light based on their temperature. According to the Researchers, these properties united with a good biocompatibility will facilitate usage of the semiconductor nanoparticles in nanosurgery and photothermal therapy.
June 2, 2017
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Simple colour changing test can help speed up research for cancer drugs
A simple colour changing test to help scientists investigate potential cancer drugs has been developed by University of Bath scientists, allowing research to progress at a much greater speed than has been possible until now.
March 27, 2017
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Simple new Device for Capturing Circulating Tumor Cells Needs No Microfluidics
Scientists at Worcester Polytechnic Institute are reporting in journal Nanotechnology on a new way of trapping circulating tumor cells that doesn't rely on microfluidic techniques common in previously developed devices. Because it is arguably a simpler approach that relies more on simple mechanics, the device is cheap and works impressively well.
January 6, 2017
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Single-dose radiotherapy effectively reduces spinal cord compression symptoms
A common complication in people with metastatic cancer, spinal cord compression is a major detriment to quality of life. Radiation treatment is widely used to relieve pain and other symptoms, but there is no standard recommended schedule, and approaches currently vary. Findings from a phase III clinical trial show that a single radiation treatment is as effective as a full week of radiation.
June 5, 2017
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Skull base surgeons help pioneer method of extracting tumors from ear canal
A surgical team is helping to pioneer a new minimally invasive procedure that extracts vertigo-inducing tumors from the inner ear without having to remove a large piece of skull, as is usually required.
September 15, 2016
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Smart nanoparticle called PEARLs a promising gem to target, treat tumors
A team of biomedical researchers has discovered a 'smart' organic, biodegradable nanoparticle that uses heat and light in a controlled manner to potentially target and ablate tumors with greater precision.
July 14, 2016
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Smoking Still Takes Big Toll in U.S. Cancer Deaths
Habit is linked to close to one-third of fatal cancers in people 35 and older, study finds
October 22, 2016
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Some Have Unrealistic Hopes for Cancer Trials
Study finding is a red flag, researcher says
September 23, 2016
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Some types of cancers are heavily dependent on sugar, study shows
In a new study, scientists at The University of Texas at Dallas have found that some types of cancers have more of a sweet tooth than others.
May 26, 2017
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Southern Research aims to develop new radiosensitizers that may greatly benefit cancer patients
Two out of three cancer patients are treated with radiation, but the therapy often fails to wipe out the tumor or slow its growth. Southern Research is working to develop a new class of drugs that will help the radiation deliver a more powerful punch to the disease.
June 9, 2017
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SPECT/CT combined with fluorescence imaging detects micrometastases
Dual-modality imaging could guide cancer surgery
May 8, 2017
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Sperm May One day Cure some Cancers
Sperm is creepy. it's wiggly, and there's usually millions of them and unless they're... y'know, going after an egg, sperm are useless. that was until some German scientists came up with a system to deliver medication using the tiny swimmers.
April 13, 2017
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Spousal cancer diagnosis can lead to decline in household income
Caring for a husband or wife with cancer significantly diminishes family income, according to researchers from the University of Georgia Terry College of Business, who tracked changes in employment and income among working-age couples in Canada.
April 24, 2017
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Statins may hold keys to future cancer treatment, reseachers find
High doses of drugs commonly used to fight high cholesterol can destroy a rogue protein produced by a damaged gene that is associated with nearly half of all human cancers, researchers have found.
January 24, 2017
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Stem cells contribute to origin of cancer in different organs of mice
The idea that stem cells - special cells that divide to repair and generate tissues - might be the major determinant of cancer risk has provoked great debate in the scientific community. some researchers maintain that environmental carcinogens are more important in defining cancer risk. now researchers at St. Jude Children's Research Hospital and the University of Cambridge, England, have confirmed the crucial contribution of stem cells to the origins of cancer in different organs of mice. the results appear online today in the journal Cell.
August 25, 2016
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Stem-cell transplants show limited benefit for double-hit lymphoma patients in remission
Penn study finds therapy does not make relapse less likely
May 15, 2017
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Sticky nanoparticles could play vital role in fighting cancers
Sticky nanoparticles that deliver drugs precisely to their targets – and then stay there – could play a crucial role in fighting ovarian and uterine cancers.
September 20, 2016
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Stiff, hypoxic regions of tumors trigger cancer progression
When Hippocrates first described cancer around 400 B.C., he referred to the disease's telltale tumors as "karkinos" -- the Greek word for crab. the "Father of Western Medicine" likely noted that cancer's creeping projections mirrored certain crustaceans, and the tumors' characteristic hardness resembled a crab's armored shell.
September 13, 2016
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Structural knowledge of the DNA repair complex
New research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. the results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides a mechanism for cancer cells to resist chemotherapy.
March 21, 2017
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Study clarifies role of KLF12 in CRC tumor growth
Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses.
July 29, 2016
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Study describes algorithm that can predict growth of cancerous tumors
A new study by Yusheng Feng, professor of mechanical engineering at the University of Texas at San Antonio (UTSA), describes an algorithm that can predict the growth of cancerous tumors, which could help medical professionals judge the best treatment options for patients.
April 18, 2017
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Study examines psychological impact of tumor gene testing in subset of NCI-MATCH patients
The ECOG-ACRIN Cancer Research Group has received federal approval to add a quality-of-life research study, COMmunication and Education in Tumor Profiling (EAQ152) or 'COMET' to the NCI-MATCH (EAY131) trial, already underway. Using feedback surveys before and after a patient receives their tumor gene testing to select cancer treatment, the COMET study will gather data to determine whether increasing knowledge about the limitations and benefits of the test can reduce a patient's level of distress about the process. the trial will open later this month.
August 19, 2016
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Study examines role of religion in cancer screening
Does religion affect people's likelihood of being screened for cancer?
October 7, 2016
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Study explains how genetic mutations linked to telomere capping complex contribute to cancers
Telomeres are the protective structures at the end of chromosomes and are essential for the faithful replication and protection of our genome. Defects in telomere function can lead to genomic instability in cancer, while the gradual shortening of telomeres is associated with the aging of human cells. a key component of the telomere protecting mechanism is a multi-protein complex called shelterin.
April 10, 2017
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Study explains long-term pulmonary outcomes among childhood cancer survivors
A team of researchers from nine leading academic hospitals and research centers have published a paper in the early online edition of the journal Cancer that describes pulmonary outcomes among childhood cancer survivors. the study also evaluates the impact of complications such as asthma, chronic cough, emphysema and recurrent pneumonia on daily activities.
August 16, 2016
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Study explores effects of androgen deprivation therapy on overall geriatric health
Androgen drives many prostate cancers. But the body uses androgen for muscle growth and maintenance, among other functions. An ongoing study published in the Journal of Clinical Oncology along with the American Society for Clinical Oncology (ASCO) Annual Meeting 2017 evaluates the effects of androgen deprivation therapy not just on patients' physical function but on global geriatric health, including skills of daily living. Because the study is longitudinal, following individual patients from before treatment through the course of their care, findings can help to define not only the characteristics of men who will need supportive care, but when in treatment this care should begin.
June 5, 2017
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Study finds fly growth mimics cancer cells, creating new tool in fight against disease
Scientists who study a molecule known to play a role in certain types of cancers and neurodegenerative disorders have a powerful new tool to study this compound due to new research.
January 24, 2017
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Study finds high rates of increasing obesity in patients with history of cancer
A study at Columbia University's Mailman School of Public Health showed that obesity was more prevalent in patients with a history of cancer than in the general population, and survivors of colorectal and breast cancers were particularly affected. the study is among the first to compare rates of obesity among U.S. cancer survivors and adults without a history of cancer. Findings are published online in the Journal of Clinical Oncology.
August 09, 2016
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Study finds late onset and short duration of pain relief treatment in many terminal cancer patients
Many terminal cancer patients are not getting adequate pain relief early enough, according to a University of Leeds study.
September 15, 2016
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Study finds limited evidence that styrene causes cancer in humans
Limited evidence that styrene, a high volume plastics chemical and animal carcinogen, causes cancer in humans
February 14, 2017
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Study finds link between fertility treatments and pediatric tumors
Ben-Gurion University of the Negev (BGU) researchers have found that babies born from mothers who underwent fertility treatments are at increased risk of developing many types of pediatric cancers and tumors (neoplasms).
April 25, 2017
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Study finds no clear benefit of stem-cell transplant for double-hit lymphoma patients in remission
Patients with double hit lymphoma (DHL) who undergo autologous stem-cell transplantation (autoSCT) after achieving remission are not more likely to remain in remission or live longer than patients who do not undergo autoSCT, according to a new analysis from the Perelman School of Medicine and the Abramson Cancer Center of the University of Pennsylvania.
May 15, 2017
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Study finds potential therapeutic target for KRAS-driven cancers
Approximately 20 percent of all human cancers have mutations in a gene called KRAS. KRAS-mutant cancers are among the most difficult to treat, with poor survival and resistance to chemotherapy. Researchers at University of California San Diego School of Medicine and Moores Cancer Center used microRNAs – small pieces of genetic material – to systematically inhibit thousands of other genes to find combinations that are specifically lethal to cancer cells driven by a KRAS mutation.
October 3, 2016
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Study highlights importance of long-term research in bringing new cancer therapies to market
New drugs to treat cancer that are now emerging are the end products of research begun in the 1970s and '80s, a new study by Bentley University has found, demonstrating the importance of long-term research in bringing new therapies to market. the research, published in the journal PLOS One, appears as Congress considers deep cuts to the National Institutes of Health, whose budget funds research into cancer and other diseases.
March 28, 2017
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Study highlights racial/ethnic disparities in genomic sequencing
As scientists learn more about which genetic mutations are driving different types of cancer, they're targeting treatments to small numbers of patients with the potential for big payoffs in improved outcomes.
August 19, 2016
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Study identifies new therapeutic target in Non-Hodgkin's Lymphoma
Researchers have discovered that an enzyme called uracil-DNA glycosylase (UNG) protects the ends of B cell chromosomes to facilitate the proliferation of these antibody-producing cells in response to infection. the study also suggests that targeting this enzyme may help treat certain types of non-Hodgkin's lymphoma.
October 3, 2016
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Study offers new insights into mechanisms underlying action of motor proteins
A study published today offers a new understanding of the complex cellular machinery that animal and fungi cells use to ensure normal cell division, and scientists say it could one day lead to new treatment approaches for certain types of cancers.
January 4, 2017
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Study potentially explains vulnerability of young cancer patients to treatment toxicities
Scientists have discovered a potential explanation for why brain and heart tissues in very young children are more sensitive to collateral damage from cancer treatment than older individuals.
December 22, 2016
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Study provides insights into how cancer cells can evade FGFR inhibitors
A new study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has identified a mechanism by which cancer cells develop resistance to a class of drugs called fibroblast growth factor receptor (FGFR) inhibitors.
March 2, 2017
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Study questions whether mistaken antibodies led cancer research down a 20-year dead end
For nearly two decades researchers have sought a way to target an estrogen receptor in the hope they could improve breast cancer survival, but a new article contends that the effort may never pan out. The reason? The target receptor does not actually appear to be where they believe it to be.
June 15, 2017
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Study reveals cancer-fighting power of onions
The next time you walk down the produce aisle of your grocery store, you may want to reach for red onions if you are looking to fight off cancer.
June 7, 2017
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Study reveals intriguing crosstalk between metabolism and epigenetics in cancer development
A study published in Briefings in Functional Genomics investigated how epigenetics can modulate human's genetic program -- it can emphasize or silence genes. the new research shows that if epigenetics is disrupted, it might switch on oncogenes (genes that in certain circumstances transform cells into tumor cells) or shut down tumor suppressors. Both events will transform cells into tumor cells and cause cancer.
March 24, 2017
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Study sheds light on determining surgical margins for feline tumors
Researchers are paving the way for more precision in determining surgical margins for an aggressive tumor common in cats by analyzing tissue contraction at various stages of the post-operative examination process.
June 13, 2017
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Study shows children present at home did not motivate parents to test for radon and tobacco smoke
A University of Louisville School of Nursing researcher has found that the presence of children in the home did not motivate parents to test and mitigate for radon and secondhand tobacco smoke, both of which cause lung cancer. the findings highlight a need to raise awareness on these exposure risks and their long-term impact on children.
August 31, 2016
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Study shows involvement of lipid metabolism in tumour metastasis
A study headed by Salvador Aznar Benitah, ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona), and published today in Nature identifies metastasis-initiating cells through a specific marker, namely the protein CD36. this protein, which is found in the membranes of tumour cells, is responsible for taking up fatty acids. CD36 activity and dependence on lipid (fat) metabolism distinguish metastasis-initiating cells from other tumour cells.
December 6, 2016
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Study shows promising clinical activity, safety results of KTE-C19 in aggressive B-cell non-hodgkin lymphoma
Immune cellular therapy is a promising new area of cancer treatment. Anti-cancer therapeutics, such as chimeric antigen receptor (CAR) modified T cells, can be engineered to target tumor-associated antigens to attack and kill cancer cells. this allows for an improved precision medicine approach to treating cancer.
December 5, 2016
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Study shows strong long-term survival rates for patients with GIST
Nearly one in four patients with incurable gastrointestinal stromal tumors (GIST) treated with Gleevec will survive 10 years, a new report outlines.
February 20, 2017
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Study suggests revolutionary way to make cancer cells more susceptible to existing chemotherapies
The same signal that drives aggressive growth in a deadly cancer cell type also triggers coping mechanisms that make it "notoriously" hard to kill, according to a study published online December 15 in Cell. When stressed, this cell type - far more than most cancer cells - encases its genetic messages in protein globs called "stress granules" that lessen the effect of chemotherapies.
December 16, 2016
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Study suggests targeting UNG enzyme may help treat non-Hodgkin's lymphoma
Researchers have discovered that an enzyme called uracil-DNA glycosylase (UNG) protects the ends of B cell chromosomes to facilitate the proliferation of these antibody-producing cells in response to infection. the study "UNG protects B cells from AID-induced telomere loss," which will be published online October 3 ahead of issue in the Journal of Experimental Medicine, also suggests that targeting this enzyme may help treat certain types of non-Hodgkin's lymphoma.
October 3, 2016
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Study uncovers new genetic markers linked to testicular germ cell tumors
Testicular cancer is relatively rare with only 8,850 cases expected this year in the United States. A majority of testicular cancer, 95 percent of all cases, begins in testicular germ cells, which are the cells responsible for producing sperm. Testicular germ cell tumors (TGCT) are the most common cancer in men aged 20 to 39 years in the U.S. and Europe. Peter Kanetsky, Ph.D., M.P.H., chair of the Cancer Epidemiology Department at Moffitt Cancer Center, and colleagues from the International TEsticular CAncer Consortium (TECAC), launched a large analysis of five major testicular cancer studies to investigate genetic risk factors linked to TGCT.
June 13, 2017
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Study unveils new way to starve tumors to death
Blocking cancer cells' metabolism may make treatments more effective, less toxic
January 24, 2017
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Study uses ethnically diverse sample to identify predictors of early substance use
Girls who were overweight as children are likely to begin using cigarettes, marijuana or alcohol at an earlier age than their healthy-weight peers, according to a new study by researchers in the Indiana University School of Education.
June 29, 2016
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Study: Cancer cells grow faster when transplanted into fatty, obese tissue
It's not just what's inside breast cancer cells that matters. it's also the environment surrounding cancer cells that drives the disease, according to researchers at the University of North Carolina Lineberger Comprehensive Cancer Center. In an abstract that will be presented April 3 at the American Association for Cancer Research Annual Meeting 2017, researchers will report their preliminary findings that cancer cells grew faster when they were transplanted into fatty, obese tissue.
March 31, 2017
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Study: Cancer patients who used symptom-reporting Internet tool lived longer
Cancer patients who reported their symptoms to their cancer care providers using a web-based survey lived longer than those patients who did not, according to a study led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher.
June 5, 2017
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Sulforaphane, a phytochemical in broccoli sprouts, ameliorates obesity
Sulforaphane, a phytochemical in broccoli sprouts, is known to exert effects of cancer prevention by detoxicating chemical compounds taken into the body and by enhancing anti-oxidation ability. In the present study, experiments with mice demonstrate that sulforaphane ameliorates obesity, the conclusion based on the two functions of sulforaphane newly uncovered; amelioration of obesity through enhancing energy consumption by browning of adipocytes, and reduction of metabolic endotoxemia through improving gut bacterial flora.
March 7, 2017
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Supercomputers assist in search for new, better cancer drugs
Researchers use advanced computers to virtually discover and experimentally test new chemotherapy drugs and targets
May 1, 2017
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Supercomputers reveal how cell membranes keep cancer-causing proteins turned off
Two biophysicists have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein.
April 4, 2017
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Supramolecular protein fishing with molecular baits
IBS researchers modified an anti-cancer drug to capture, purify a cancer-prone protein
March 2, 2017
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SurgVision Displays Tumors During Surgery
At RSNA 2016 in Chicago, SurgVision, a Dutch firm, was showing off its intra-surgical molecular probe fluorescence imaging system designed for excising hard to spot tumors. the system relies on novel dyes attached to tumor-seeking antibodies and a multi-spectral fluorescence imaging camera to spot the dye within tissue.
December 13, 2016
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Surgically implanted neurostimulator system helps alleviate chronic pain
When the damaged nerves in Anthony Newberry's foot healed incorrectly after a workplace accident, it left him feeling "like my foot was exploding for hours at a time," he says. Unable to work or walk, the 38-year-old Millington, Illinois, construction worker became depressed, dependent upon pain medication and seriously considering suicide.
August 30, 2016
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Surprise advance in the treatment of adult cancers
An epigenetic modification that might be the cause of 15% of adult cancers of the throat linked to alcohol and tobacco use was identified. this discovery was unexpected since it seemed highly improbable that this kind of alterations of the epigenome found in children could also target an epithelial tumor like throat cancer that occurs only in adults.
January 11, 2017
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Survival Continues to Improve for Most Cancers
Still, more progress is needed and racial disparities remain, U.S. report finds
March 31, 2017
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Surviving cancer may increase risk of birth complications
A recent study, published in JAMA Oncology, finds a link between surviving cancer and health risks for the survivors' future newborns. the study provides new information about this little-studied interaction.
March 23, 2017
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Swarms of Bacteria Deliver Cancer Drug Directly to Tumors
Scientists at Polytechnique Montreal, Universite de Montreal, and McGill University have tinkered with flagellated bacteria, to deliver drugs to tumors. Swarms of these bacteria (Magnetococcus marinus), each having an iron-oxide crystal that can be pulled at with a magnet, and liposome vesicles attached to them that carry an anti-cancer drug, were injected into mice with colorectal cancer.
August 17, 2016
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Swarms of magnetic bacteria could be used to deliver drugs to tumors
One of the biggest challenges in cancer therapy is being able to sufficiently deliver chemotherapy drugs to tumors without exposing healthy tissues to their toxic effects. Magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs, researchers have demonstrated.
September 22, 2016
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'Sweet spot' where tissue stiffness drives cancer's spread
Researchers have now found that physical forces exerted between cancer cells and the ECM are enough to drive a shape change necessary for metastasis. Those forces converge on an optimal stiffness that allows cancer cells to spread.
February 21, 2017
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Sweetening connection between cancer and sugar
Scientists have found that some types of cancers have more of a sweet tooth than others.
May 26, 2017
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Synthesizing Hexagonal Silver Nanoplates Using Tumor Suppressor Protein p53
An innovative technique that combines tumor suppressor protein p53 and biomineralization peptide BMPep was successful in synthesizing hexagonal silver nanoplates, indicating an effective approach for regulating the nanostructure of inorganic materials.
May 4, 2017
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Misc. - T

T-Bear brings hope to kids diagnosed with cancer at Seattle Children's Hospital
He may not be able to fly, or be as fast as the speed of light, but for children who have been diagnosed with cancer at Seattle Children's, the cuddly teddy bear who wears a mask and purple cape is still a super hero to them - he gives them strength. His name is T-Bear and he's bringing hope to children with cancer.
September 28, 2016
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T-cell signaling process central to immune response
Scientists obtain first glimpse of the molecular mechanism by which recognition of an antigen by the T cell receptor triggers the first steps leading to an immune response
May 16, 2017
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Targeting cancer stem cells improves treatment effectiveness, prevents metastasis
Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma -- the most common head and neck cancer and the second-most common skin cancer, according to a new study. Head and neck squamous cell carcinoma is a highly invasive form of cancer and frequently spreads to the cervical lymph nodes.
March 10, 2017
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Targeting immune cells that help tumors stay hidden could improve immunotherapy
Researchers have discovered a clue that could unlock the potential of immunotherapy drugs to successfully treat more cancers. The findings were made in mice and showed that targeting a sub-population of immune cells called regulatory T cells (T-regs) could make the drugs more effective.
June 15, 2017
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Targeting the biological clock could slow the progression of cancer
Does the biological clock in cancer cells influence tumor growth? Yes, according to a new study.
February 16, 2017
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Tattoos mark the spot for surgery, then disappear
Tattoos aren't just for body art. they can have medical applications, too. Doctors are using them on patients to mark an area for future treatment -- particularly for non-melanoma skin cancer such as basal cell carcinoma -- but the inks can cause problems. now scientists have developed a better solution. In a new article, they report a new ink that glows only under certain light conditions and can disappear altogether after a period of time.
December 21, 2016
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Technique for Blocking Capillaries to Starve and Suffocate Tumors
Researchers from Shanghai Institute of Ceramics of the Chinese Academy of Sciences and the East China Normal University have reported in journal Nature Nanotechnology on a new technique of blocking cappilaries that feed oxygen and nutrients to tumors, essentially suffocating and starving them at the same time.
January 25, 2017
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Telomere length predicts cancer risk
The length of the 'caps' of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics. Longer-than-expected telomeres -- which are composed of repeated sequences of DNA and are shortened every time a cell divides -- are associated with an increased cancer risk.
April 3, 2017
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Testicular cancer survivors with low testosterone more likely to have chronic health problems
In a large study, 38% of 491 testicular cancer survivors had low testosterone levels, known as hypogonadism. Compared to survivors with normal testosterone levels, survivors with low testosterone were more likely to have a range of chronic health problems, including high blood pressure, diabetes, erectile dysfunction, and anxiety or depression.
June 5, 2017
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Testicular cancer: Genetic test steps closer
A new study brings closer the day when healthy men will be able to undergo a genetic test that shows them if they are at higher risk of testicular cancer.
June 12, 2017
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Testing for malaria -- or cancer -- at home, via cheap paper strips
Chemist develops tech to save lives in rural Africa
June 29, 2016
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Testing lesions in food pipe could provide early and accurate diagnosis of oesophageal cancer
Genetically analysing lesions in the food pipe could provide an early and accurate test for oesophageal cancer, according to research led by Queen Mary University of London (QMUL), Academic Medical Center in Amsterdam and Arizona State University. the study, published in Nature Communications, shows that some cells that are 'born to be bad' could be identified early on, preventing the need for repeated endoscopies.
August 19, 2016
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Tethered nanoparticles make tumor cells more vulnerable
MIT researchers have devised a way to make tumor cells more susceptible to certain types of cancer treatment by coating the cells with nanoparticles before delivering drugs.
March 19, 2017
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Tethered nanoparticles make tumor cells more vulnerable
New strategy could improve performance of some immune-based drugs
March 19, 2017
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Texas A&M researcher suggests ways to unlock intrinsic hope in cancer patients
Can cancer patients tap into a certain kind of hope that is often overlooked but incredibly therapeutic and healing? Research by University Distinguished Professor of Marketing Leonard Berry of Texas A&M University's Mays Business School suggests clinicians can help patients tap into this kind of hope.
June 9, 2017
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Texas hospital struggles to make IBM's Watson cure cancer
Audit committee questions procurement compliance
March 9, 2017
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The 10 best cancer blogs
Receiving a cancer diagnosis can be distressing not only for the person involved, but also for their friends, family, and coworkers. We have located the best cancer blogs that provide groundbreaking treatment news, general information, and support for everyone impacted by cancer.
June 15, 2017
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The antibody that normalizes tumor vessels
Scientists have discovered that their antisepsis antibody also reduces glioma, lung and breast cancer progression in mice, outlines a new report.
December 12, 2016
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The best treatment for laryngeal cancer? this approach helps decide
Study finds 'exceptional' long-term survival when a single dose of chemotherapy selects patients for chemo-radiation or surgery
February 2, 2017
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The brain remembers missing hands and fingers even decades after amputation, study reveals
Our brains have a detailed picture of our hands and fingers, and that persists even decades after an amputation, Oxford University researchers have found. the finding could have implications for the control of next generation prosthetics.
August 30, 2016
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The Chemicals In Burnt Toast and Crispy Fries Won't Kill You, But the Calories Might
We'Re Pretty Bad at Identifying Which Cancer Risks Make a Difference
January 27, 2017
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The life-saving treatment that's being thrown in the trash
Today, transplanted umbilical cord blood can treat or cure more than 80 conditions.
March 28, 2017
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The Mednet launches its 'Quora for cancer," an online medical knowledge base
A New York City startup called the Mednet today launched a platform that gives physicians a knowledge-sharing tool that's as easy to use as Quora, but provides them with expert answers about the latest research in their field. the site has focused, so far, strictly on cancer.
March 21, 2017
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The Problem with Cancer-Sniffing Dogs
Your Canine Pal Probably Won't Have a Job at your Local Hospital
October 4, 2016
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The role of a telomere capping complex in cancer revealed
Scientists have unveiled part of the protein complex that protects telomeres--the ends of our chromosomes. Telomeres are the protective structures at the end of chromosomes and are essential for the faithful replication and protection of our genome. Defects in telomere function can lead to genomic instability in cancer, while the gradual shortening of telomeres is associated with the aging of human cells.
April 10, 2017
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The tech industry and the search for a cancer cure
Nvidia, Intel, IBM and other Silicon Valley companies are making finding a cure a high priority.
November 28, 2016
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Therapy flags DNA typos to rev cancer-fighting T cells
Disabled spell-checker identifies patients who may benefit from immune therapy
June 9, 2017
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Therapy 'Step Forward' for Non-Hodgkin Lymphoma
Early trial results termed 'fantastic step forward' in fight against non-Hodgkin lymphoma
September 12, 2016
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This Synthetic Bone Implant Could Replace Painful Marrow Transplants
Thanks to advances in medicine, bone marrow transplants are no longer the last resorts they once were. Every year, thousands of marrow transplants are performed, a common treatment for ailments from bone marrow disease to leukemia. But because they first require a patient undergo radiation to kill off any existing bone marrow stem cells, marrow transplants remain incredibly hard on a patient.
May 9, 2017
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Thousands of rare cancer-related gene mutations found
Innovative research, published in PLOS Computational Biology this week, explains how thousands of "previously ignored genetic mutations" may contribute to the growth of malignant tumors. Using a new statistical approach, scientists find new patterns in proteins.
April 21, 2017
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Time to initiating cancer therapy is increasing, associated with worsening survival
Based on US analysis of common solid tumors in study population of 3.6 million
June 5, 2017
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Timing of chemo affects inflammation, mice study suggests
Finding 'sweet spot' for drug administration could help patients
January 24, 2017
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Tiny Embeddable Sensor Unveiled for Measuring pH, Chloride
Imec and Holst Centre, two sister research organizations based in Belgium and Holland, unveiled a tiny sensor for measuring a fluid's pH and chloride levels. Chloride is an electrolyte involved in a variety of cellular processes, including regulating the body's pH level. Being able to measure these parameters may make them popular metrics for assessing athletic performance and for personalized medicine.
December 20, 2016
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Tiny Rocket Could One day Deliver Meds Or Hunt for Cancer In your Body
Ready for Bubble-Propelled Blastoff
June 30, 2016
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To Help Prevent Colon Cancer, 'Listen to your Gut'
Belly pain and black or bloody stools should not be ignored, doctor says
September 28, 2016
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Toward glow-in-the-dark tumors: new fluorescent probe could light up cancer
A fluorescent probe lights up the enzyme beta-galactosidase in a cell culture. the glowing probe-enzyme combination could make tumors fluoresce, allowing surgeons to cut away cancer while leaving healthy tissue intact.
March 28, 2017
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Tracking cancer's signaling pathways
Malignant melanoma is one of the most common and dangerous types of cancer. Researchers have investigated how and why brown pigmented moles turn into malignant melanoma using innovative robot technology. The insights gained can simplify methods of diagnosis in the future; furthermore, they suggest that certain cosmetic products and creams should be avoided.
May 23, 2017
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Traditional Japanese art inspires a futuristic innovation: Brain 'organoids'
The ancient Japanese art of flower arranging was the inspiration for a groundbreaking technique to create tiny "artificial brains" that could be used to develop personalized cancer treatments.
December 5, 2016
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TransOral Robotic Surgery may provide good outcomes, survival for oropharyngeal cancer patients
A new study from researchers at Henry Ford Hospital finds an incisionless robotic surgery - done alone or in conjunction with chemotherapy or radiation - may offer oropharyngeal cancer patients good outcomes and survival, without significant pain and disfigurement.
September 16, 2016
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Treating cancer with drugs for Diabetes and hypertension
A combination of a Diabetes medication and an antihypertensive drug can effectively combat cancer cells. the team of researchers has also reported that specific cancer cells respond to this combination of drugs.
December 27, 2016
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Triple-threat cancer-fighting polymer capsules for guided drug delivery
These microcarriers may offer an entirely different approach to treating solid human tumors of numerous pathologic subtypes by delivering their encapsulated drug cargo to a tumor and protecting against collateral tissue damage.
March 30, 2017
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Triple-threat cancer-fighting polymer capsules for guided drug delivery
Chemists at the University of Alabama at Birmingham have designed triple-threat cancer-fighting polymer capsules that bring the promise of guided drug delivery closer to preclinical testing.
March 30, 2017
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TSRI researchers develop novel drug delivery method for treating cancers
Scientists from the Florida campus of the Scripps Research Institute (TSRI) have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.
March 16, 2017
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TSRI scientists identify GlyRS protein that launches cancer growth
Scientists at the Scripps Research Institute (TSRI) have identified a protein that launches cancer growth and appears to contribute to higher mortality in breast cancer patients.
June 28, 2016
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TSRI study reveals how circadian clocks may influence cancer growth
A new study led by scientists at the Scripps Research Institute (TSRI) describes an unexpected role for proteins involved with our daily "circadian" clocks in influencing cancer growth.
November 16, 2016
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Tumor Associated Macrophages are Polarized to an Anti-Cancer Phenotype by Ferumoxytol
Ferumoxytol is an FDA-approved therapeutic for the treatment of anemia. it's a solution of iron oxide nanoparticles roughly 17-31 nm in diameter and replenishes the body's iron levels. Researchers from Stanford University have discovered a new use for these nanoparticles in that they may actually be protective against metastatic cancer spreading to the liver.
October 20, 2016
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Tumor cells get stiff before becoming invasive
Breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive. the discovery identifies a new signal in tumor cells that can be further explored when designing cancer-targeting therapies.
May 16, 2017
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Tumor microenvironment acts as a mechanism of resistance to chemotherapy
Researchers have discovered the importance of tumor environment as a source of resistance to treatment in colorectal cancer, the fourth most common cancer and the leading cause of cancer death worldwide.
September 6, 2016
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Tumor necrosis factor may help control blood pressure, study suggests
Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of blood pressure.
April 6, 2017
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Tumor Paint lights the way for surgeons during brain surgery
In December of last year, Laura Coffman began to notice that something wasn't quite right with her 2-year-old son, Hunter. He was leaning to one side and seemed to lose his balance easily. When he became lethargic and started vomiting a few days later on Dec. 28, she knew it was time to see the pediatrician.
September 28, 2016
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Tumor Patch Brings Three Weapons to Fight Cancer
MIT researchers have created an implantable patch for the administration of three completely different therapies to tumor sites in order to kill and prevent the recurrence of cancer. the hydrogel patch is embedded with gold nanorods that are able to heat up and ablate nearby tissue when illuminated by infrared light.
July 26, 2016
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Tumor-seeking salmonella treats brain tumors
New approach produces 20 percent survival rate in rat model where few typically live
January 11, 2017
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Tumor.com
For resources and information on Types of Tumors and Fibroid tumor.
Provides Information
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Tumorigenesis may be induced from neighboring tissues, study suggests
Current view is that cancer development is initiated from cells that acquire initial DNA mutations. These in turn provoke additional defects, and ultimately the affected cells begin to proliferate in an uncontrolled manner to develop primary tumors. These can later spread and create metastases, or secondary tumors, in other parts of the body.
June 2, 2017
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Tumour suppressor gene has greater anti-cancer activity than previously thought
Researchers at the National University of Ireland Galway have shown that the TP53 gene has even greater anti-cancer activity than previously thought
September 22, 2016
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Two investigational antitumor agents work better together against MPNST and neuroblastoma
The synergistic effects of a kinase inhibitor and an oncolytic herpes virus show promise for difficult-to-treat neuroblastomas and malignant peripheral nerve sheath tumors
February 9, 2017
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Two key proteins preserve vital genetic information
Understanding this basic cell division may help researchers understand the origins of some key genetic disorders, including cancer
August 22, 2016
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Two thirds of cancer mutations result from completely random DNA mistakes
An increased focus on early detection will be needed to effectively treat the disease
March 23, 2017
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Two-Thirds of all Cancer Mutations Are Unavoidable, Scientists Claim
In a study that's bound to attract considerable controversy, a pair of researchers are claiming that between 60 and 66 percent of all cancer-causing mutations are the result of random DNA copying errors, making them essentially unavoidable. the new research is offering important insights into how cancer emerges, and how it should be diagnosed and treated--but many questions remain.
March 23, 2017
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Misc. - U

U.S. Cancer Death Rates Continue to Fall: Report
Researchers credit declines in smoking, better detection and treatment
January 5, 2017
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U.S. Cancer Deaths Decline Over Three Decades
But clusters of high death rates remain in some pockets of the country, study finds
January 24, 2017
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Ubiquitous and influential
New insights into the intricate molecular underpinnings of ubiquitin signaling
February 13, 2017
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UC researchers find stem cell vaccine to enhance immune responses against tumors in animal models
Researchers at the University of Cincinnati have found that a cancer stem cell vaccine, engineered to express a pro-inflammatory protein called interleukin-15 (IL-15) and its receptor (IL-15Ralpha), caused T cell production in animal models and enhanced immune responses against tumors.
May 10, 2017
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UC3M scientists use mathematical description to explain how tumors induce growth of blood vessels
Universidad Carlos III de Madrid (UC3M) has carried out a study that mathematically explains how tumors induce the growth of blood vessels. the study maintains that the tips of the blood vessels expand like a soliton, a solitary wave similar to a tsunami.
October 17, 2016
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UCM scientists design biosensor capable of detecting cancer autoantibodies at early stages
Before a malignant tumor is developed, the immune system tries to fight against proteins that are altered during their formation, producing certain cancer antibodies. a biosensor developed by scientists from the Complutense University of Madrid has been able to detect these defensive units in serum samples of patients with colorectal and ovarian cancer. the developed method is faster and more accurate than traditional methods.
January 11, 2017
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UI scientists reveal how high-dose vitamin C damages cancer cells
Vitamin C has a patchy history as a cancer therapy, but researchers at the University of Iowa believe that is because it has often been used in a way that guarantees failure.
January 9, 2017
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Ultrafast detection of a cancer biomarker enabled by innovative nanobiodevice
Like DNA, ribonucleic acid (RNA) is a type of polymeric biomolecule essential for life, playing important roles in gene processing. Short lengths of RNA called microRNA are more stable than longer RNA chains, and are found in common bodily fluids. the level of microRNA in bodily fluids is strongly correlated with the presence and advance of cancer. this means that microRNA can act as an easily accessible biomarker to diagnose cancer, which causes over 14% of deaths annually worldwide.
March 8, 2017
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Ultrafast detection of a cancer biomarker enabled by innovative nanobiodevice
Pioneering nanobiodevice can isolate cancer biomarkers quickly with high resolution
March 8, 2017
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Ultrtasmall nanoparticles show ability to induce cell death in tumors
Nanoparticles known as Cornell dots, or C dots, have shown great promise as a therapeutic tool in the detection and treatment of cancer.
September 23, 2016
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UMass researchers develop new class of photodynamic molecules for treating deep-tissue tumors
UMass Medical School scientist Gang Han, PhD, and his team have designed a new class of molecules used in photodynamic therapy that are able to direct lamp light deep into tissue to kill cancer tumors.
December 5, 2016
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Understanding proteins and their impact on immune system
Researchers have made a breakthrough in the understanding of how our genetic make-up can impact on the activity of the immune system and our ability to fight cancer.
May 30, 2017
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Understanding randomization of clinical trials crucial to success
A research team analyzed linguistic approaches to help cancer patients better comprehend the concept of randomization, being assigned by chance to treatment or control groups, in clinical trials.
December 21, 2016
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Unexpected link between cancer and autism
Researchers have observed that a protein called SHANK prevents the spread of breast cancer cells to the surrounding tissue. the SHANK protein has been previously studied only in the central nervous system, and it is known that its absence or gene mutations are related to autism.
March 9, 2017
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Unexpected role for epigenetic enzymes in cancer
A new study focused on a family of enzymes – known as KDM5 – that have been shown in previous studies to be involved in cancer cell growth and spreading.
January 6, 2017
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UNMC seeking patients with lymphoma to evaluate two-drug oral therapy
The University of Nebraska Medical Center is seeking 24 patients to enroll in a Phase 2a study to evaluate the safety and efficacy of two oral cancer drugs for patients with diffuse large B-cell lymphoma who have relapsed or are resistant to other traditional therapies. Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma.
December 9, 2016
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Urine-based biomarkers for early cancer screening test
A new study has introduced a new technique that validates urine-based biomarkers for early detection of cancer. the research team expects that this may be potentially useful in clinical settings to test urinary EV-based biomarkers for cancer diagnostics.
March 7, 2017
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USC researchers to demonstrate how wearable technology can improve cancer treatment
Researchers at the University of Southern California will demonstrate how using wearable technology and smartphones can improve cancer treatment at a White House event on Oct. 3.
September 28, 2016
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Using 'fire to fight fire' to combat disease could make it worse, tests show
A treatment billed as a potential breakthrough in the fight against disease, including cancer, could back-fire and make the disease fitter and more damaging, new research has found. Ground-breaking research has found that introducing 'friendlier' less-potent strains into a population of disease-causing microbes can lead to increased disease severity.
December 30, 2016
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Using immune cells to deliver anti-cancer drugs
Biomedical engineers have created a smart, targeted drug delivery system using immune cells to attack cancers.
January 3, 2017
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Using the immune system to fight cancer: an interview with Dr Charles Akle
We all produce as many as 100,000 different types of cancer cells every day, which are recognized and eliminated by our extraordinarily efficient immune system.
September 12, 2016
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Using thermal measurement to improve cancer therapy outcomes
Researchers at the Adolphe Merkle Institute at the University of Fribourg, along with colleagues from the Zurich University of Applied Sciences, Winterthur, have developed a novel characterization method, NanoLockin, which can help optimize the design of nanoparticles used in a recent form of cancer therapy known as magnetic hyperthermia (Nanoscale, "A lock-in-based method to examine the thermal signatures of magnetic nanoparticles in the liquid, solid and aggregated states").
November 24, 2016
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Utilizing tumor suppressor proteins to shape nanomaterials
A new method combining tumor suppressor protein p53 and biomineralization peptide BMPep successfully created hexagonal silver nanoplates, suggesting an efficient strategy for controlling the nanostructure of inorganic materials.
May 3, 2017
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Utilizing tumor suppressor proteins to shape nanomaterials
A new method combining tumor suppressor protein p53 and biomineralization peptide BMPep successfully created hexagonal silver nanoplates, suggesting an efficient strategy for controlling the nanostructure of inorganic materials.
May 3, 2017
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UTSW researchers develop new nanoparticle vaccine immunotherapy that targets multiple tumor types
Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types.
April 24, 2017
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UTSW surgeons remove acoustic neuromas through small incisions in the ear canals
A surgical team at UT Southwestern Medical Center is helping to pioneer a new minimally invasive procedure that extracts vertigo-inducing tumors from the inner ear without having to remove a large piece of skull, as is usually required.
September 15, 2016
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Misc. - V

Venetoclax safe, shows promise in patients with acute myelogenous leukemia
Patients whose acute myelogenous leukemia (AML) had relapsed or was resistant to chemotherapy and those who were deemed unable to tolerate chemotherapy experienced responses to the selective BCL-2 inhibitor venetoclax (Venclexta), with complete remissions in some, according to phase II clinical trial data.
August 12, 2016
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VIB-KU Leuven scientists identify new mechanism that impacts cancer growth
Scientists at VIB-KU Leuven have identified a new mechanism that impacts tumor growth. the typical lack of oxygen in tumors doesn't only stimulate proliferation, but also offsets the important role of the protein PHD2 as 'cancer cell killer'. a possible solution lies in blocking the enzyme PP2A/B55, which restores the function of PHD2 and consequently slows down cancer growth.
February 14, 2017
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Virtual Reality Initiative aims to provide emotional benefit to young cancer patients
The University of Southern California (USC) Norris Comprehensive Cancer Center has partnered with Springbok Cares to provide a unique Virtual Reality (VR) initiative for patients in the Adolescent and Young Adult (AYA) Cancer program at USC (AYA@USC). the patient initiative is designed to provide a library of curated cinematic and interactive VR experiences using the most advanced media technology available to lessen discomfort and anxiety with quality escapist entertainment.
October 3, 2016
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Vitamin C and antibiotics: A new one-two 'punch' for knocking-out cancer stem cells.
Cancer stem cells, which fuel the growth of fatal tumors, can be knocked out by a one-two combination of antibiotics and Vitamin C, report investigators.
June 12, 2017
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Vitamin C can be used to target and kill cancer stem cells, research finds
Researchers measure the impact on cancer stem cell metabolism of 3 natural substances, 3 experimental pharmaceuticals and 1 clinical drug.
March 8, 2017
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Vitamin C effective in targeting cancer stem cells
Researchers have measured the impact on cancer stem cell metabolism of three natural substances, three experimental pharmaceuticals and one clinical drug.
March 8, 2017
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Vitamin D decreases risk of cancer, new study suggests
Low vitamin D status may increase the risk of cancer, suggests new research. the study is a randomized clinical trial of the effects of vitamin D supplementation on all types of cancer combined.
March 28, 2017
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Vitamin D, calcium supplementation among older women does not significantly reduce risk of cancer
Among healthy postmenopausal women, supplementation with vitamin D3 and calcium compared with placebo did not result in a significantly lower risk of cancer after four years, according to a study.
March 28, 2017
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Misc. - W

Watch Awesome Games Done Quick's Latest Speedrun Event for Cancer Research
Awesome Games Done Quick's first event of 2017 is underway.
January 9, 2017
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Watching movies can replace general anesthesia for kids with cancer having radiotherapy
Children with cancer could be spared dozens of doses of general anesthesia by projecting a video directly on to the inside of a radiotherapy machine during treatment, according to new research.
May 8, 2017
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Watson claims to predict cancer, but who trained it to 'think?'
Watson cannot read handwriting. Machine learning's true potential is tied to human inputs.
August 16, 2016
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We Are Closer to Curing all Diseases Than we Think
For Cancer Care, Access to Treatment May be the Biggest Obstacle
September 30, 2016
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'Weekend warriors' have lower risk of death from cancer, cardiovascular disease
One or two exercise sessions per week may be enough to reduce health risks in men and women
January 9, 2017
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What is dance psychology? what types of question are you trying to answer?
Dance psychology is the study of dance and dancers from a scientific and psychological perspective. what we're trying to understand is what happens when people dance and why, we are looking at it from a healthcare perspective, which might suggest dancing is good for you.
March 8, 2017
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What makes pancreatic cancer so aggressive?
Key factor for aggressiveness of pancreatic cancer discovered
April 18, 2017
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What the hair of a fly tells us about cancer
Cells divide into two identical cells that then divide in turn, meaning that any tissue can grow exponentially. But the moment comes when some of them have to develop into specialized cells. On the back of a fly, for example, a cell must know that when it splits, it will give birth to two different cells: a hair and a neuron.
June 6, 2017
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What you don't Know About Cancer can Kill You
Too few Americans realize that obesity, alcohol and inactivity boost risk for disease, survey finds
February 1, 2017
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When targeting cancer genes, home in on the one percent
Many cancer-related mRNAs bind a protein and uncover a hidden site that's a possible Achilles heel
July 27, 2016
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Where body fat is carried can predict cancer risk
Carrying fat around your middle could be as good an indicator of cancer risk as body mass index (BMI), according to new research.
May 24, 2017
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Where you Live May play Role in Cancer Risk
Rural areas a bit safer than urban ones; environmental threats seem key, study says
May 8, 2017
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Whitehead Institute researchers identify mechanism underlying cancer drug-resistance
The use of proteasome inhibitors to treat cancer has been greatly limited by the ability of cancer cells to develop resistance to these drugs. But Whitehead Institute researchers have found a mechanism underlying this resistance–a mechanism that naturally occurs in many diverse cancer types and that may expose vulnerabilities to drugs that spur the natural cell-death process.
December 27, 2016
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Whole-exome sequencing may routinely miss detecting some disease-causing genes, say researchers
Whole-exome DNA sequencing -- a technology that saves time and money by sequencing only protein-coding regions and not the entire genome -- may routinely miss detecting some genetic variations associated with disease, according to Penn State researchers who have developed new ways to identify such omissions.
April 24, 2017
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Why high-dose vitamin C kills cancer cells
Low levels of catalase enzyme make cancer cells vulnerable to high-dose vitamin C
January 9, 2017
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Why thick skin develops on our palms and soles, and its links to cancer
Scientists from Queen Mary University of London have discovered that foot callouses/keratoderma (thickened skin) can be linked to cancer of the esophagus (gullet), a disease which affects more than 8000 people in the UK each year.
February 1, 2017
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Winning teams of the Nanotechnology Startup Challenge in Cancer
Ten winners of the Nanotechnology Startup Challenge in Cancer were announced today by the Center for Advancing Innovation. the challenge featured eight inventions, conceived and developed by scientists from three participating institutes of the National Institutes of Health -- the National Cancer Institute, the National Institute of Biomedical Imaging and Bioengineering, and the National Heart, Lung, and Blood Institute -- as well as extramural, "third-party" inventions, which were discovered and advanced outside of the NIH.
September 20, 2016
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World Cancer Congress: DITTA urges development of integrated care approaches in medical technology
Dealing effectively with the burden of cancer on healthcare systems demands an integrated approach to care, with medical technology occupying a pivotal role. In its session at the World Cancer Congress, DITTA, the Global Diagnostic Imaging, Healthcare IT and Radiation Therapy Trade Association explained how fragmentation within healthcare systems makes it difficult for them to effectively manage complex conditions such as cancer where the various dimensions of care - prevention, screening, diagnosis, treatment and palliation -- are inseparable.
November 4, 2016
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WSU researchers develop portable laboratory on smartphone to detect cancer biomarker
Washington State University researchers have developed a low-cost, portable laboratory on a smartphone that can analyze several samples at once to catch a cancer biomarker, producing lab quality results.
October 18, 2016
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WSU Team Delivers "Nanotherapeutics" Directly to Tumor for First Time
A team of researchers from Washington State University (WSU) have shown a method to supply a drug to a tumor by attaching it to a blood cell. the innovation would enable doctors to target tumors with anticancer drugs that might otherwise destroy healthy tissues.
May 16, 2017
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Misc. - Y

Yale Researchers Use Sticky Nanoparticles to Progress Treatment of Cancer
Sticky nanoparticles capable of delivering drugs specifically to their targets and then remain there could be extremely useful in the fight against uterine and ovarian cancers.
September 21, 2016
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Years Spent Overweight Boosts Women's Cancer Risk
Study found odds for 4 types rose 10 percent for every decade of obesity
August 16, 2016
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Yet another Cancer Drug Trial is on Hold Following Patient Deaths
As 2016 draws to a close, two of what started out as this year's most promising new cancer therapies have ground to a halt amidst patient deaths during the experimental treatments.
December 28, 2016
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Young cancer survivors have twice the risk of suicide
Survivors of cancer diagnosed before the age of 25 had a more than two-fold increased risk of suicide compared to their non-cancer peers, a new report suggests.
November 30, 2016
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Young survivors have social difficulties years after cancer diagnosis
Cancer affects tens of thousands of young people each year. Receiving a cancer diagnosis can be emotionally and socially challenging, particularly for adolescents or young adults, who are already experiencing a range of age-related changes. new research investigates the long-term impact of a cancer diagnosis on young adults.
March 19, 2017
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Yoshinori Ohsumi wins Nobel Prize in Medicine for work on cells that eat themselves
Autophagy, or 'self-eating,' plays a role in everything from aging to cancer
October 3, 2016
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Misc. - Z

Zig-zagging device focuses high-energy radiation emissions
Physicists have found a way to better control high-energy particle emissions in an undulator device that could potentially be used as a source of radiation for cancer treatment or nuclear waste processing
June 12, 2017
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Ovarian Cancer - D

Diet high in calcium, low in lactose may decrease risk of ovarian cancer in African-American women
Research from Rutgers Cancer Institute of new Jersey and and other U.S. health and academic institutions shows a diet high in calcium and low in lactose may reduce the risk of ovarian cancer in African-American women. the work, which appears in the latest edition of the British Journal of Cancer, also found sun exposure in the summer months may reduce the risk of developing the disease in this population.
September 16, 2016
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Deaths from ovarian cancer decline worldwide due to oral contraceptive use
Deaths from ovarian cancer fell worldwide between 2002 and 2012 and are predicted to continue to decline in the USA, European Union and, though to a smaller degree, in Japan by 2020, according to new research. the main reason is the use of oral contraceptives and the long-term protection against ovarian cancer that they provide.
September 6, 2016
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Does Baby Powder Cause Ovarian Cancer?
Leading cancer and women's health groups say probably not
November 4, 2016
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Ovarian Cancer - G

Gene signature in ovarian cancer predicts survival and offers new drug target
A new study has identified a gene signature that predicts poor survival from ovarian cancer. the study also identified genes which help the cancer develop resistance to chemotherapy -- offering a new route to help tackle the disease.
June 28, 2016
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Gene testing could help predict ovarian cancer patients' sensitivity to new class of drugs
Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs, a major new study reveals.
December 22, 2016
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Ovarian Cancer - H

Higher socioeconomic status linked to lower ovarian cancer risk in African American women
Higher socioeconomic status (SES) is associated with lower ovarian cancer risk in African American women, according to the results of a study by investigators at the Medical University of South Carolina (MUSC) and elsewhere reported online August 3 by the American Journal of Epidemiology. It showed that the risk of ovarian cancer was 29 percent lower among women with a college degree or more compared with those who had a high school degree or less.
August 04, 2016
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Hypertension linked to better outcomes for subset of ovarian cancer patients
Hypertension, or high blood pressure, may come with a plus side, at least for a subset of women with ovarian cancer. new research from epidemiologists at Roswell Park Cancer Institute, published in the journal Cancer Causes & Control, provides evidence that hypertension and Diabetes and the use of medications to treat these common conditions may influence the survival of ovarian cancer patients -; sometimes in a detrimental way, but in the case of hypertension medications, perhaps as a benefit.
April 17, 2017
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Ovarian Cancer - I

Is the Pill Tied to Fewer Ovarian Cancer Deaths?
Rates down 16 percent in U.S., 8 percent in Canada, and 10 percent in Europe over a decade: study
September 7, 2016
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Ovarian Cancer - L

Liquid biopsies offer hope for earlier treatment, better tracking of ovarian cancer
A promising new way to monitor and treat recurrence of ovarian cancer has been identified by researchers -- a hard-to-detect disease that claims many lives. new research finds liquid biopsies from blood tests and DNA sequencing can detect a return of ovarian cancer long before a tumor reappears.
July 20, 2016
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Ovarian Cancer - M

Miniature Brain and Skull Found Growing Inside Teen's Ovary
while performing a routine appendectomy on a 16-year-old girl, Japanese surgeons uncovered an ovarian tumor containing bits of hair, a thin plate of bone–and a miniature brain.
January 6, 2017
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MIT engineers develop more sensitive approach to reveal ovarian tumors
Most ovarian cancer is diagnosed at such late stages that patients' survival rates are poor. However, if the cancer is detected earlier, five-year survival rates can be greater than 90 percent.
April 10, 2017
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Murine study finds potential boost for ovarian cancer drug Olaparib
Researchers have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings suggest that this FDA-approved ovarian cancer medicine has the potential to treat a wider range of cancer types than currently indicated.
January 25, 2017
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Ovarian Cancer - N

New guidance for targeting residual ovarian tumors
Findings support new strategy of continuous drug delivery by implantable device
May 23, 2017
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New imaging test can show key enzyme in ovarian cancer to help guide treatment choices
A new imaging test may provide the ability to identify ovarian cancer patients who are candidates for an emerging treatment that targets a key enzyme cancer cells need to survive. Currently, epithelial ovarian cancer patients with BRCA1 mutations are considered candidates for the treatment, but there is no method to measure the enzyme levels to help guide treatment choices.
April 3, 2017
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New possibility in treating aggressive ovarian cancer, study shows
A recent discovery may lead to a new treatment strategy for an aggressive ovarian cancer subtype. Ovarian cancer is the most deadly gynecological cancer and it is the seventh most common cancer in women worldwide. Most women with ovarian cancer are diagnosed at the advanced stage, which is more difficult to treat.
November 30, 2016
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New technology can detect tiny ovarian tumors
'Synthetic biomarkers' could be used to diagnose ovarian cancer months earlier than now possible
April 10, 2017
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Ovarian Cancer - O

Online information can increase feelings of worry and fear among women at risk of ovarian cancer
Researchers at Cardiff University have found that online information about ovarian cancer can cause as much worry as comfort for women at high risk of developing the disease, in a new study published in ecancer.
June 30, 2016
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Ovarian Cancer Drug Given Fast-Track Approval
The anti-cancer drug Rubraca (rucaparib) has been granted accelerated approval by the U.S. Food and Drug Administration to treat advanced ovarian cancer.
December 21, 2016
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Ovarian cancer researchers find biomarker linked to prognosis in aggressive disease type
Ovarian cancer researchers have identified a protein biomarker expressed on the surface of tumor cells in high-grade serous ovarian cancer, the most common and lethal subtype of the disease.
March 7, 2017
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Ovarian cancer study uncovers new biology
Proteogenomics provides new inroads to diagnosis, treatment
June 29, 2016
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Ovarian cancer target molecule may be key to blocking its spread
Blocking a protein found on the surface of ovarian cancer cells could prevent or reduce the spread of the disease to other organs, according to new research.
March 2, 2017
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Ovarian cancer: Effective immunotherapy steps closer with new T cell study
At a scientific meeting this week, researchers report some progress in developing an immunotherapy for ovarian cancer. However, they also outline the considerable challenges that remain before the treatment can be made effective for this and other cancers that have solid tumors.
April 5, 2017
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Ovarian removal to prevent ovarian cancer should not be an option for premenopausal women, research finds
The controversial practice of ovary removal in premenopausal women to prevent ovarian cancer should be discontinued in women who are not at high risk of cancer, new evidence suggests.
September 29, 2016
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Ovarian Cancer - P

Pathologists identify new potential target in ovarian serous cancer
HER4 expression may be linked to chemotherapy resistance, lower survival rate
March 18, 2016
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Preventive procedure for ovarian cancer adopted without adverse surgical outcomes
Routinely removing fallopian tubes during surgery may help prevent ovarian cancer, which has limited screening options
July 12, 2016
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Ovarian Cancer - R

Researchers develop tiny 3D tissue models to study how ovarian cancer develops in women
With a unique approach that draws on 3D printing technologies, a team of University of Wisconsin-Madison researchers is developing new tools for understanding how ovarian cancer develops in women.
July 27, 2016
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Researchers identify how ionising radiation can cause cancer by damaging DNA
For the first time, researchers from the Wellcome Trust Sanger Institute and their collaborators have been able to identify in human cancers two characteristic patterns of DNA damage caused by ionising radiation. These fingerprint patterns may now enable doctors to identify which tumours have been caused by radiation, and investigate if they should be treated differently.
September 12, 2016
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Ovarian Cancer - S

Sanford study explores protein's role in improving survival of ovarian cancer patients
A Sanford Research lab is studying a protein's role in improving survival in ovarian cancer patients. Findings published in Oncogenesis indicate a higher level of a specific protein correlates with an increased survival rate and decrease in the spreading of cancer cells.
December 21, 2016
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Scientists find promising new method to detect and treat recurrence of ovarian cancer
Researchers at the Mayo Clinic Center for Individualized Medicine have found a promising new way to monitor and treat recurrence of ovarian cancer -- a hard-to-detect disease that claims many lives. new research from George Vasmatzis, Ph.D., of the Department of Laboratory Medicine and Pathology at Mayo Clinic, finds liquid biopsies from blood tests and DNA sequencing can detect a return of ovarian cancer long before a tumor reappears.
July 21, 2016
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Studies question use of readmission rate as metric in surgeries for ovarian cancer patients
To reduce costs and improve quality of care, the Centers for Medicaid and Medicare Services (CMS) has made reducing readmission rates a priority, yet research studies presented today at the Society of Gynecologic Oncology's 2017 Annual Meeting for Women's Cancer question the use of the metric in surgeries performed in patients with ovarian cancer. the presentations find that readmission rate as a metric of quality of care in ovarian cancer surgeries focuses on short-term outcomes but is not an ideal measure of patient survival in the long run.
March 13, 2017
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Study examines role of HOX genes in ovarian cancer resistance
A new UK study has identified a gene signature that predicts poor survival from ovarian cancer. the study also identified genes which help the cancer develop resistance to chemotherapy - offering a new route to help tackle the disease.
June 28, 2016
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Study finds 12 genetic variants that raise the risk of ovarian cancer
Ovarian cancer is a common form of cancer and a leading cause of cancer death among women. the genes we inherit affect our chances of developing ovarian cancer, and a new genomic study identifies 12 genetic variants associated with the risk.
March 27, 2017
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Study shows feasibility to adopt salpingectomy in large scale clinical practice without surgical repercussions
A surgical procedure recommended to reduce the future risk of ovarian cancer has been successfully implemented throughout Kaiser Permanente in Northern California without a change in surgical outcomes, according to research published today in the journal Obstetrics & Gynecology.
July 12, 2016
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Study suggests ovary removal to prevent ovarian cancer should be discontinued in premenopausal women
A Mayo Clinic research team has found evidence suggesting that the controversial practice of ovary removal in premenopausal women to prevent ovarian cancer should be discontinued in women who are not at high risk of cancer. the study showed that women under 46 who had both ovaries removed experienced a significantly elevated risk of multiple chronic health conditions that included depression, hyperlipidemia, cardiac arrhythmias, coronary artery disease, arthritis, asthma, chronic obstructive pulmonary disease and osteoporosis.
September 29, 2016
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Ovarian Cancer - T

T-cells can be directed to treat a variety of ovarian cancers
Scientists identified an ideal target for an immunological approach to ovarian cancer treatment with no observed adverse effects
July 28, 2016
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Ovarian Cancer - V

Vitamin C can target and kill cancer stem cells, study shows
Cancer is currently one of the top killers worldwide, and the number of cancer cases is only expected to rise. Although there are a number of therapies available, most of them are toxic and cause serious side effects. new research examines the impact of the natural vitamin C on cancer cell growth.
March 13, 2017
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Pancreatic Cancer - B

Blood Test for Pancreatic Cancer Shows Promise
Scientists aim for earlier detection, when tumors are treatable
May 24, 2017
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Pancreatic Cancer - C

Curbing immune system infighting could make treatment more effective for pancreatic cancer
Internal conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer. Curbing this infighting has the potential to make treatment more effective, according to a study led by researchers from NYU Langone Medical Center and its Perlmutter Cancer Center.
August 25, 2016
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Pancreatic Cancer - G

Gold nanoparticles could be the key to developing a treatment for pancreatic cancer
A diagnosis of pancreatic cancer is often a death sentence because chemotherapy and radiation have little impact on the disease. In the U.S. this year, some 53,000 new cases will be diagnosed, and 42,000 patients will die of the disease, according to the National Institutes of Health.
October 19, 2016
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Gold Nanoparticles Fight Off Pancreatic Tumor Growth
A research team from University of Oklahoma, Mayo Clinic, Mount Sinai, and University of Missouri have shown that gold nanoparticles can help stop the growth of pancreatic tumors in mice models.
October 22, 2016
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Gold Nanoparticles May Help Improve Pancreatic Cancer Treatment
A pancreatic cancer diagnosis is often a death sentence for patients because both radiation and chemotherapy have very little effect on the disease. According to the National Institutes of Health, there will be nearly 53,000 new cases and 42,000 deaths due to pancreatic cancer this year in the U.S.
October 20, 2016
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Pancreatic Cancer - H

High rate of tumor shrinkage among pancreatic cancer patients
Adding cisplatin to standard gemcitabine/nab-paclitaxel drug treatment provided a very high rate of tumor shrinkage for patients with advanced pancreatic cancer, according to the results of a pilot clinical trial. These statistically significant and clinically meaningful improvements in overall response and survival rates resulted from a phase Ib/II clinical study.
April 25, 2017
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Pancreatic Cancer - I

Immune system infighting explains pancreatic cancer's aggression
Conflict between cell types explains why the immune system struggles to recognize and attack pancreatic cancer, report researchers. Curbing this infighting has the potential to make treatment more effective, according to a study.
August 25, 2016
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Innovative therapy strategy for pancreatic cancer uses engineered exosomes targeting mutated KRAS gene
Study demonstrates that 'iExosomes' shut down growth of pancreatic tumors in mice
June 7, 2017
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Interpace Diagnostics introduces new AccuCEA Insights for diagnosing and treating pancreatic cancer
Interpace Diagnostics Group, a company that provides clinically useful molecular diagnostic tests and pathology services for evaluating risk of cancer by leveraging the latest technology in personalized medicine for better patient diagnosis and management, reported today that the Company has launched a new version of their AccuCEA™ product called "Insights" for Gastroenterologists who focus on diagnosing and treating pancreatic cancer.
August 24, 2016
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Pancreatic Cancer - L

Light scattering spectroscopy helps doctors identify early pancreatic cancer
New optical tool predicts malignant potential of cysts with 95 percent accuracy, compared to 58 percent accuracy with current test
March 13, 2017
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Low-Dose Aspirin May Cut Pancreatic Cancer Risk
Chinese-based study, analysis of previous research point to everyday use decreasing the odds
December 20, 2016
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Pancreatic Cancer - M

MGH researchers discover how obesity increases inflammation, desmoplasia in PDAC patients
Massachusetts General Hospital (MGH) investigators have discovered the mechanism by which obesity increases inflammation and desmoplasia - an accumulation of connective tissue - in the most common form of pancreatic cancer.
July 7, 2016
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Pancreatic Cancer - N

Natural compound from a deep-water marine sponge found to reduce pancreatic tumor size
A deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound, report scientists.
August 18, 2016
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New test may improve pancreatic cancer diagnoses
Method relies on five proteins from bits of tumor circulating in blood
May 24, 2017
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Newfound signal helps pancreatic cancer cells hide from immune system
Researchers have uncovered another pathway by which pancreatic cancer cells turn off the system charged with attacking them.
April 10, 2017
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Novel marine natural product appears to reduce pancreatic tumor size
Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound.
August 18, 2016
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Pancreatic Cancer - P

Pancreatic cancer cells find alternative source of nutrition to avoid starvation
Pancreatic cancer cells avert starvation in dense tumors by ordering nearby support cells to supply them with an alternative source of nutrition. this is the finding of a study in cancer cells and mice published August 10 in Nature.
August 11, 2016
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Pancreatic cancer patients may live longer by traveling to academic hospital for operation
New study findings link traveling to an academic medical center for surgical removal of pancreatic or thyroid cancer with higher quality surgical care for both cancers. Although the study shows better care at high-volume surgical centers for patients with pancreatic or thyroid cancer, few patients travel for their cancer operations, it concludes.
May 1, 2017
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Pancreatic cancer: 'Softening' tumors before chemotherapy may extend survival
New research finds that using a drug to "soften" tumors before chemotherapy doubles survival and reduces cancer spread in mouse models of pancreatic cancer - a disease with a low survival rate and few treatments for inoperable tumors.
April 6, 2017
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Pancreatic cysts increase overall risk of pancreatic cancer, study shows
A look back at more than half a million patient records has established that patients with pancreatic cysts have a significantly higher overall risk of pancreatic cancer compared to those without such cysts, according to a study in the July issue of GIE: Gastrointestinal Endoscopy, the journal of the American Society for Gastrointestinal Endoscopy (ASGE).
July 12, 2016
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Potential role for vitamin a in pancreatic cancer discovered
Vitamin a may have a role to play in tackling the commonest form of pancreatic cancer, scientists have discovered. Pancreatic ductal adenocarcinoma (PDAC), the most common type of malignancy of the pancreas, is extremely aggressive and very difficult to treat. Many scientists are currently investigating the genetic mutations and biochemical signalling pathways that enable cancer cells to spread to other parts of the body.
September 7, 2016
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Pancreatic Cancer - R

Regular aspirin use lowers pancreatic cancer risk by 50%, new study finds
Researchers studied patients with newly diagnosed pancreatic cancer at 37 Shanghai hospitals from December 2006 to January 2011. the 761 patients were interviewed in person about their use of aspirin per day or week and their ages when the use started and stopped. they were matched with control patients identified from the Shanghai Residents Registry.
January 6, 2017
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Regular aspirin use may reduce risk for pancreatic cancer
Regular use of aspirin by people living in Shanghai, China, was associated with decreased risk for developing pancreatic cancer, according to data published.
December 20, 2016
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Researchers find novel way to induce pancreatic cancer cell death
Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma, is the most lethal and aggressive of all cancers. Unfortunately, there are not many effective therapies available other than surgery, and that is not an option for many patients. In an effort to better understand pancreatic cancer at a molecular level, scientists conducted a study to try to identify molecules that could become the next generation of therapeutics for this type of cancer.
April 10, 2017
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Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system
Researchers at NYU Langone Medical Center and its Perlmutter Cancer Center have uncovered a critical pathway by which pancreatic cancer cells turn off the immune system charged with attacking them.
April 7, 2017
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Pancreatic Cancer - S

Scientists identify aggressive pancreatic cancer cells and their vulnerability
Preclinical findings show how tumors exploit cellular plasticity to change into resistant type
February 9, 2017
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Scientists identify cell-surface receptor for progranulin
Progranulin is produced and secreted by most cells in the body. from skin to immune cells, brain to bone marrow cells, progranulin plays a key role in maintaining normal cellular function. In cancer, too much progranulin makes tumors (particularly prostate carcinomas) more aggressive and metastatic, whereas in neurodegenerative diseases, too little is associated with disease onset and progression
November 30, 2016
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Scientists identify vulnerabilities of highly aggressive pancreatic cancer cells
Researchers have identified a gatekeeper protein that prevents pancreatic cancer cells from transitioning into a particularly aggressive cell type and also found therapies capable of thwarting those cells when the gatekeeper is depleted.
February 9, 2017
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Scientists track metabolic pathways to find drug combination for pancreatic cancer
Cancer researchers have long observed the value of treating patients with combinations of anti-cancer drugs that work better than single drug treatments. Now, in a new study using laboratory-grown cells and mice, scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways.
August 24, 2016
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Sentinels in the blood: a new diagnostic for pancreatic cancer
A crafty method to identify pancreatic cancer early in its development has been devised by researchers. Their technique relies on the sensitive detection of extracellular vesicles (EVs) -- tiny bubbles of material emitted from most living cells.
February 6, 2017
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Small molecule may offer new way to fight pancreatic cancer
In a search for much needed new treatments for pancreatic cancer - a deadly and aggressive disease with a poor survival rate - scientists are looking for clues at the molecular level. Now, a new study finds that a small molecule called MIR506 appears to play an important role in the fate of pancreatic cancer cells, and may offer a way to stop their growth and ability to spread.
April 11, 2017
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Pancreatic Cancer - T

TGen study identifies potential new drug targets to alleviate pain in pancreatic cancer patients
The Translational Genomics Research Institute (TGen) has discovered potential drug targets to reduce pain in pancreatic cancer patients.
November 7, 2016
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TUM scientists shed new light on metastases in the liver at early stage of pancreatic cancer
Pancreatic cancer is an exceptionally aggressive type of cancer. Frequently, metastases already start to grow in other organs, particularly often in the liver, before the original tumor was even detected. Scientists from the Technical University of Munich (TUM) have now discovered a molecular mechanism, which is responsible for the prominent susceptibility of the liver to metastases at such an early stage.
October 7, 2016
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Tumor DNA in blood may serve as prognostic marker of pancreatic cancer
The presence of circulating tumor DNA (ctDNA) isolated from blood samples of patients with pancreatic adenocarcinoma was associated with poor outcomes, report investigators.
December 19, 2016
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Pancreatic Cancer - U

Unraveling mysteries of pancreatic cancer's resistance to standard therapies
Blocking inflammation after radiation therapy led to improved survival in mouse model
January 24, 2017
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Prostate Cancer - Numbers

4 in 10 men may not be receiving adequate prostate cancer treatment in England
Almost 4 in 10 men with high-risk or locally advanced prostate cancer (prostate cancer that is likely to or that has already spread beyond the prostate) may be "undertreated" by the failure to use radiotherapy or in some circumstances surgery, according to new results. the most common form of under-treatment is the use of hormonal treatments alone without additional radiotherapy or surgery. this means that some of the men diagnosed with high-risk or locally advanced prostate cancer may not be receiving the best treatment.
March 27, 2017
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Prostate Cancer - A

A potential cure for metastatic prostate cancer? Treatment combination shows early promise
Pilot study suggests that a new paradigm including drug therapy, surgery, and radiation may cure previously incurable cancer
April 18, 2017
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Active surveillance improves health related quality of life in low risk prostate cancer patients
Active surveillance has become an increasingly important alternative to surgery, chemotherapy, or radiation treatment for men diagnosed with low risk prostate cancer. However, what is the impact of as on health related quality of life (HRQoL) in patients selected or opting for this conservative form of disease management?
July 25, 2016
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Advanced prostate cancer treatment failure due to cell reprogramming
Response to anti-androgen therapy decreased in mice that were missing tumor suppressor genes
May 4, 2017
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Aggressive prostate cancer secrets revealed in landmark study
A landmark study has revealed the reason why men with a family history of prostate cancer who also carry the BRCA2 gene fault have a more aggressive form of prostate cancer.
January 10, 2017
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ANGLE's Parsortix system could help predict metastasis in prostate cancer
ANGLE plc, the specialist medtech company, is delighted to announce that researchers from the Barts Cancer Institute, Queen Mary University of London, have presented new results at the World CDx Europe 2017 conference in London of their work with ANGLE's Parsortix system in prostate cancer. the new findings suggest a broader range of potential applications for Parsortix in prostate cancer from early to late disease prognosis.
March 31, 2017
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Prostate Cancer - B

Bioactive compound from neem plant shows promising effects on prostate cancer
Oral administration of nimbolide, over 12 weeks shows reduction of prostate tumour size by up to 70 per cent and decrease in tumour metastasis by up to 50 per cent
September 29, 2016
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Blood test uses nanotechnology to predict aggressive prostate cancer accurately
A new diagnostic developed by Alberta scientists will allow men to bypass painful biopsies to test for aggressive prostate cancer. The test incorporates a unique nanotechnology platform to make the diagnostic using only a single drop of blood, and is significantly more accurate than current screening methods.
June 9, 2017
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Breakthrough study stops fat-eating prostate cancer cells
Patients with castration resistant prostate cancer (CRPC) usually have a poor prognosis. In part, this is due to the cancer's ability to resist anti-androgen therapy. a study shows that combining a CPT1A inhibitors with anti-androgen therapy increases the cancer's sensitivity to the anti-androgen drug enzalutamide.
May 15, 2017
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Prostate Cancer - C

Can prostate cancer metastasis be stopped before it starts?
Research team identifies role for particular microRNA
January 24, 2017
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Changes in benign tissue adjacent to prostate tumors could better predict recurrence
Changes in benign tissues next to prostate tumors may provide an early warning for patients at higher risk for biochemical recurrence after a radical prostatectomy, a study by researchers at Case Western Reserve University and Johns Hopkins Medical Institutions shows.
July 6, 2016
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Clinical study examines impact of yoga on side-effects caused by prostate cancer treatment
Men who attended a structured yoga class twice a week during prostate cancer radiation treatment reported less fatigue and better sexual and urinary function than those who didn't, according to a clinical trial led by the Perelman School of Medicine at the University of Pennsylvania.
April 6, 2017
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Clinical trial shows benefit of yoga for side effects of prostate cancer treatment
Twice-weekly yoga led to better physical, sexual, emotional, and social health, study finds
April 6, 2017
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Combination of examination and radical local therapy can improve survival of men with prostate cancer
Men with very high-risk prostate cancer, who are treated at hospitals with a high proportion of administered radical local treatment (radiotherapy or prostatectomy), only have half of the mortality risk of men who are treated at hospitals with the lowest proportion.
August 08, 2016
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Combined treatment regimen shows early promise in eliminating metastatic prostate cancer
Pilot study suggests that a new paradigm including drug therapy, surgery, and radiation may cure previously incurable cancer, according to a new study in Urology®
April 18, 2017
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Consumption of a bioactive compound from Neem plant could significantly suppress development of prostate cancer
Oral administration of nimbolide, over 12 weeks shows reduction of prostate tumor size by up to 70 per cent and decrease in tumor metastasis by up to 50 per cent, report investigators.
September 29, 2016
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Could antidepressants stop prostate cancer from spreading?
In almost all cases where prostate cancer spreads to other areas of the body, the disease spreads to the bone first. In a new study, researchers reveal the discovery of an enzyme that helps prostate cancer cells to invade bone. Furthermore, certain antidepressant medications may have the potential to block this enzyme.
March 13, 2017
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Prostate Cancer - D

Does Second Opinion Sway Prostate Cancer Patients?
Most choose treatment they originally planned to follow, study finds
November 7, 2016
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Drug could activate innate anti-tumor immunity to eradicate aggressive prostate cancer in mice
Cabozantinib, a drug already used to treat patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors that entice neutrophils - the first-responders of the immune system - to infiltrate the tumor, where they triggered an immune response that led to tumor clearance.
March 9, 2017
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Prostate Cancer - E

Early MRI may lower costs for prostate cancer treatment
Study finds MRI and MRI-guided biopsy cheaper long-term than standard ultrasound
May 17, 2017
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Expert calls for shorter radiation use in prostate cancer treatment
Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to scientists.
February 21, 2017
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Experts Criticize Report on Rising Prostate Cancer
American Cancer Society says methodology used for recent study was flawed
July 21, 2016
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Experts walk back on prostate screening; men 55-69 should consider it
New data tipped the scales just a bit, showing some benefit to screening.
April 11, 2017
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Prostate Cancer - F

'First in human' trial defines safe dosage for small molecule drug ONC201 for solid cancer tumors
A 'first in human' clinical trial examining the small molecule drug ONC201 in cancer patients with advanced solid tumors shows that this investigational drug is well tolerated at the recommended phase II dose. That's according to investigators whose research also showed early signs of clinical benefit in patients with advanced prostate and endometrial cancers.
March 22, 2017
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For early prostate cancer, a watchful eye is just as good as treatment
In 10-year study, deaths were rare even without radiation or surgery.
September 16, 2016
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For men with prostate cancer, emotional distress may lead to more aggressive treatment
The anxiety many men experience after being diagnosed with prostate cancer may lead them to choose potentially unnecessary treatment options, researchers report.
January 11, 2017
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Prostate Cancer - G

Genetic testing can help deliver precision medicine to men with advanced prostate cancer
Genetic testing in men with advanced prostate cancer could pick up a significant proportion whose disease may be caused by inherited mutations in genes involved in repairing DNA damage, a major new study reveals. Testing prostate cancer patients for mutations in key DNA repair genes could identify those who may benefit from precision treatments that specifically target DNA repair weaknesses in cancer cells, say researchers.
July 7, 2016
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Germline genetic testing necessary for men with metastatic prostate cancer
Men with metastatic prostate cancer should be considered for germline genetic testing of DNA repair genes, regardless of age or family history, according to a team of researchers from Memorial Sloan Kettering Cancer Center (MSK), Fred Hutchinson Cancer Research Center, Dana-Farber Cancer Institute, University of Washington School of Medicine, University of Michigan, and the Institute of Cancer Research Royal Marsden Hospital.
July 8, 2016
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Prostate Cancer - H

Hope for metastatic prostate cancer patients: Targeted alpha therapy shows impressive results
Nearly three years of research have brought about remarkable results for the majority of 80 patients subjected to targeted alpha therapy of metastatic prostate cancer. the first assessments describes a full response in two patients in critical clinical condition with extensive metastases.
December 21, 2016
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How Biosensors Are Being Used To Treat Prostate Cancer
Like most geeks, our perceptions of futuristic medical technology were heavily shaped by Star Trek. The image of Bones waving his tricorder in front of some poor redshirt afflicted with an alien plague gave us the fantasy of a non-invasive form of treatment without all those icky fluids and needles.
June 15, 2017
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Prostate Cancer - I

Identification of gene defects helps treatment of prostate cancer
The current method of treating prostate cancer involves identifying gene defects, which could help with the diagnosis of cancer and the development of individualized cancer treatments for patients.
November 4, 2016
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Increasing the odds of prostate cancer detection
A radiologist reports that he uses magnetic resonance technology to diagnose prostate cancer with more than 90 percent success rate.
July 25, 2016
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Innovative procedure combining MRI and ultrasound can accurately diagnose prostate cancer
New research confirms that an innovative procedure combining MRI and ultrasound to create a 3D image of the prostate can more accurately locate suspicious areas and help diagnose whether it's prostate cancer.
September 14, 2016
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IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets
Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure.
August 16, 2016
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It may be time to abandon dreaded digital rectal exam, research shows
The dreaded finger exam to check for prostate cancer used to be a mainstay of check-ups for older men. with its value now in question, some doctors share the risks and benefits with their patients and let them decide. So, should they or shouldn't they?
September 6, 2016
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Italian-style coffee could halve the risk of prostate cancer
New research brings some good news for men who like a caffeine kick. Drinking more than three cups of Italian-style coffee daily could more than halve the risk of developing prostate cancer.
April 27, 2017
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Prostate Cancer - L

Liquid biopsy biomarkers identify prostate cancer before surgery
Prostate cancer researchers have discovered biomarkers using non-invasive liquid biopsies to identify aggressive disease before surgery.
June 28, 2016
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Prostate Cancer - M

Marker for aggressive prostate cancer doubles-up as a drug target
A marker found on aggressive prostate cancer cells could also be used as a way to guide treatments to the cancer, according to new research.
November 9, 2016
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Markers that cause toxic radiotherapy side-effects in prostate cancer identified
A new study has looked at the genetic information of more than 1,500 prostate cancer patients and identified two variants linked to increased risk of radiotherapy side-effects.
July 26, 2016
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Metastatic prostate cancer cases skyrocket: More lax screening rather than more aggressive disease?
The number of new cases of metastatic prostate cancer climbed 72 percent in the past decade from 2004 to 2013, reports a new study. the report considers whether a recent trend of fewer men being screened may be contributing to the rise, or whether the disease has become more aggressive -- or both. the highest increase is among men ages 55 to 69, who could benefit the most from screening and early treatment.
July 19, 2016
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Moffitt researchers develop novel drug that may help combat castration-resistant prostate cancer
Prostate cancer is the third most common cause of cancer-related death in men in the United States. It is estimated that 161,360 men will be diagnosed and more than 26,700 men will die from the disease in this year. The majority of these deaths are caused by prostate cancer that becomes resistant to initial therapy and spreads to other sites, called metastatic castration-resistant prostate cancer. In a study published today in Cancer Cell, Moffitt Cancer Center researchers report that a newly discovered epigenetic mechanism can lead to the development of castration-resistant prostate cancer.
June 12, 2017
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Monitoring May be Better for Prostate Cancer
In Sweden, 90 percent with very low risk disease choose this option instead of immediate treatment, researchers report
October 20, 2016
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More accurate prostate cancer prognosis
Men diagnosed with prostate cancer can be provided with a more accurate estimate of their risk of death from the disease, and treatment planned accordingly, according to new research.
August 02, 2016
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More American men with early-stage prostate cancer could opt out of immediate treatment
A new report on Swedish men with non-aggressive prostate cancer suggests that a lot more American men could safely choose to monitor their disease instead of seeking immediate radiation treatment or surgery.
October 20, 2016
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Prostate Cancer - N

New analysis shows correlation between testosterone-lowering therapy for prostate cancer and dementia
A new analysis of patients who have undergone treatment for prostate cancer shows a connection between androgen deprivation therapy - a testosterone-lowering therapy and a common treatment for the disease - and dementia, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.
March 30, 2017
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New blood test is more accurate in predicting prostate cancer risk than PSA
IsoPSA assay can help in determining the need for prostate biopsy for patients
May 15, 2017
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New diagnostic test uses machine learning to accurately detect aggressive prostate cancer
A new diagnostic developed by Alberta scientists will allow men to bypass painful biopsies to test for aggressive prostate cancer. The test incorporates a unique nanotechnology platform to make the diagnostic using only a single drop of blood, and is significantly more accurate than current screening methods.
June 9, 2017
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New findings concerning hereditary prostate cancer
It is a well-known fact that men with a family history of prostate cancer run an increased risk of developing the disease. the risk for brothers of men with prostate cancer is doubled. But a doubled risk of what, exactly? Prostate cancer my be an indolent condition that does not require treatment, or aggressive and fatal. Obviously, it makes a big difference whether a man has an increased risk of developing the indolent or the aggressive form, but until now these different risks have not been known.
July 11, 2016