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171 Health - Longivity Resources

Misc. - A

Action-consequence feature of unitization strategy improves memory in older adults, study shows
The next time you hear about the possibility of rain on the weather forecast, try imagining the umbrella tip being lodged in your home's door lock, blocking you from locking it. This mental exercise could prevent you from leaving home without an umbrella.
August 11, 2017
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Adults Who Exercise May Gain 9 'Biological' Years
Regular jogging and other pursuits delay cellular aging, study finds
May 26, 2017
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Advice for older adults on staying cool in hot weather
Risk of heat-related health problems increases with age.
July 13, 2017
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Aging in humans is mathematically inevitable, study says
A new study conducted at the University of Arizona suggested that in multicellular organisms such as humans, it is mathematically impossible to stop aging.
October 31, 2017
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Anti-aging peptide recovers fur growth, kidney health in mice
An anti-aging therapy could be one step closer; in a new study, researchers reveal how a peptide led to the destruction of cells that play a role in aging, reversing fur loss, kidney damage, and frailty in mice.
March 23, 2017
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Antidepressant use increases hip fracture risk among elderly
Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer's disease, according to a new study. the increased risk was highest at the beginning of antidepressant use and remained elevated even 4 years later.
January 11, 2017
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Apathy linked to increased risk of death in nursing home patients
In a study of nursing home patients, apathy was linked with an increased risk of dying over a 4-month period, even after controlling for depression. The study also found that apathy was present in half of nursing home patients.
August 9, 2017
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APRNs can play key role in improving nursing home care for aging population
The nation's 65 and older population is projected to double in size by the year 2050, according to the U.S. Census. To improve health care for the nation's aging population, researchers from the Sinclair School of Nursing at the University of Missouri are studying how advanced practice nurses (APRNs) can improve nursing home care by serving as leaders of health care teams in nursing homes. Findings suggest that APRN-led health care teams reduce hospitalizations related to falls, dehydration and other health issues.
August 23, 2017
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Artificial blood vessels mimic rare accelerated aging disease
Lab-grown blood vessels provide platform for studying premature aging syndrome and other rare diseases
August 15, 2017
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Astaxanthin compound shows ability to activate 'longevity gene' in mice
The University of Hawaii John A. Burns School of Medicine and Cardax, Inc., a Honolulu based life sciences company, have jointly announced the results of an animal study evaluating the effectiveness of a compound that holds promise in anti-aging therapy.
March 28, 2017
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Autoimmune disease: Could modified red blood cells lead to new treatments?
New treatments that prevent and alleviate autoimmune diseases may come from using red blood cells to carry disease-specific proteins that retrain the immune system. So concludes a study that shows such an approach works in mice with multiple sclerosis and type 1 diabetes.
March 7, 2017
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Misc. - B

Bipolar disorder speeds up biological aging
A recently published study demonstrates a link between telomere length, which is a mark of biological aging, and bipolar risk. The research helps to explain why bipolar disorder often comes hand-in-hand with other age-related diseases.
July 28, 2017
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Birth Defects in Kids May Shorten Moms' Lives
But the overall risk of early death is still quite low
December 20, 2016
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Birth of infant with major congenital anomaly linked to increased risk of death in mother
In Denmark, having a child with a major congenital anomaly was associated with a small but statistically significant increased risk of death in the mother compared with women without an affected child, according to a study appearing in the December 20 issue of JAMA. a major congenital anomaly is a structural change (such as cleft palate) that has significant medical, social or cosmetic consequences for the affected individual; this type of anomaly typically requires medical intervention.
December 20, 2016
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BMI status of older adults influences benefits accrued from memory training, study finds
In the first study to compare the results of cognitive training by body mass index (BMI) category, scientists from the Indiana University Center for Aging Research found that memory training provided only one-third the benefit to older adults with obesity than the benefit it provided to older adults without obesity.
January 10, 2017
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Brain-aging gene discovered
Genetic variant accelerates normal brain aging in older people by up to 12 years
March 15, 2017
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Brain cells found to control aging
Scientists have found that stem cells in the brain's hypothalamus govern how fast aging occurs in the body. The finding, made in mice, could lead to new strategies for warding off age-related diseases and extending lifespan.
July 26, 2017
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Breakthrough: Scientists reverse aging in human cells
New research published in the journal BMC Cell Biology shows that old human cells can be rejuvenated using chemicals similar to resveratrol, which is a substance found in red wine and dark chocolate.
November 8, 2017
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Brisk walking may help older women live longer
Older women who engage in moderate to vigorous physical activity -- such as often taking brisk walks -- may be adding years to their lives when compared with women who are not very active.
November 8, 2017
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BUSM researcher highlights link between sleep conditions and cognitive impairment in older people
Daytime sleepiness is very common in the elderly with prevalence rates of up to 50 percent. Caused by sleep-disordered breathing (SDB), a disruption of normal breathing during sleep, these cause recurrent awakenings and subsequent excessive daytime sleepiness.
January 31, 2017
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Misc. - C

Can we halt aging? Math says 'no'
The quest to slow and ultimately stop aging is as old as human culture. Infinite youth is, quite literally, the Holy Grail. However, according to a recent paper, aging is inevitable and there is nothing that can be done to stop it.
October 31, 2017
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Cannabis reverses aging processes in the brain, study suggests
Researchers restore the memory performance of Methuselah mice to a juvenile stage
May 8, 2017
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Cataract surgery tied to lower risk of death in older women
An analysis of older women taking part in a large health study has found that those with cataracts who underwent cataract surgery had a lower risk of death from any cause and from certain specific causes.
October 26, 2017
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Cell stress response sheds light on treating inflammation-related cancer, aging
Stress -- defined broadly -- can have a profoundly deleterious effect on the human body. Even individual cells have their own way of dealing with environmental strains such as ultraviolet radiation from the sun or germs. One response to stress -- called senescence -- can trigger cells to stop dividing in cases of cancer and aging. This may hold promise for treating inflammation-related disorders.
October 4, 2017
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Cellular stress 'resets lifespan profoundly'
Surprising results from a recent study show that stressing a cell can reverse signs of cellular aging. The findings might open doors to more successful ways to slow the aging process.
November 8, 2017
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Chemicals from gut bacteria maintain vitality in aging animals
Indoles help worms/flies/mice live stronger for longer
August 21, 2017
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Childhood IQ linked to longevity
Higher childhood intelligence is linked to a lower chance of dying before the age of 80. So concludes a study of nearly all children born in 1936 in Scotland, United Kingdom, which compared results of IQ tests taken at age 11 with records of death in the group over the following 68 years.
June 30, 2017
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Cellular aging and cancer development: New insight
Medical researchers have discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging. The results of the study will contribute to a better understanding of the human aging process as well as cancer development.
June 14, 2017
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Centenarians Often Healthier Than Younger Seniors
They have less chronic disease than those in their 80s and 90s, researcher says
June 15, 2017
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Collagen found to regulate epidermal proliferation in juvenile and aged skin
Type XVII collagen (COL17) is found to regulate the proliferation of epidermal cells and therefore the thickness of juvenile and aged skin, suggesting COL17 can potentially be used for future anti-aging strategies.
July 11, 2017
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Combining virtual reality and treadmill training could help reduce risk of falls in older adults
The authors say that the intervention, which combines the physical and cognitive aspects of walking, could potentially be used in gyms, rehabilitation centres or nursing homes to improve safe walking and prevent falls in older adults or people with disorders which affect movement such as Parkinson's disease.
August 11, 2016
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Could human lifespan exceed 115 years?
Last year a high-profile article was published in the journal Nature, looking at longevity or life-spans of humans. The researchers found that 115 years was the maximum that people could live up to. Beyond this, the body functions would decline and end.
June 29, 2017
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Could stem cells reverse the aging process?
Stem cells in the brain determine how quickly our bodies age, researchers have noted. But by introducing fresh stem cells, part of the aging process could be slowed down or reversed, a new study finds.
July 28, 2017
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Could Tai Chi reduce the risk of falls in older adults?
A recent meta-analysis published in the Journal of the American Geriatrics Society investigates tai chi as a way to reduce the risk of falling among older adults. This ancient art could help to improve the lives of modern at-risk individuals.
July 27, 2017
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Could these psychological traits help us live longer?
Optimism, stubbornness, a good work ethic, and a strong family bond -- could these be the ingredients to a long, happy life? A new study suggests that they might be.
December 13, 2017
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Cut Calories, Lengthen Life Span?
Study found middle-aged adults who reduced their intake showed slower biological aging
May 22, 2017
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Misc. - D

Dancing may help to combat brain aging
Get your dancing shoes on - your brain will thank you for it. This is the take-away message from a new study, which found that physical activity in later life - particularly dancing - can help to reverse the signs of brain aging.
August 29, 2017
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Deep-learning technology reveals anti-aging plant extracts
Life Extension, in collaboration with Insilico Medicine, have employed artificial intelligence to develop a novel dietary supplement of plant extracts that can activate the body's own anti-aging path ways.
October 31, 2017
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Diet, smoking and alcohol main causes of death in OECD countries
The "Health at a Glance" report 2017 shows that over 10 million deaths have been recorded in the OECD countries in 2015. Thus the number of deaths on an average in these countries is 793 per 100,000 population. The report shows that one third of these deaths were caused by ischemic heart disease, stroke and diseases of the blood vessels. One fourth of all deaths were due to cancers.
November 13, 2017
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Dietary supplement may help older adults to keep warm
Older adults are known to be more sensitive to the cold, and new research has found that a nutritional supplement called L-carnitine might one day be used as a way to jump-start the body's central heating.
September 6, 2017
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DGIST researchers discover mechanisms of inflammation-induced aging in animals
DGIST's research team has experimentally proved the hypothesis that the accumulated chronic inflammation results in the aging of animals.
January 17, 2017
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Dirty Air Raises Death Risk for U.S. Seniors
Research suggests blacks, men and the poor are especially vulnerable
June 28, 2017
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Discovery of link between RNA quality control and longevity may shed light on mechanisms behind aging
The vigors of youth and the greener pastures of yesteryears. some might refer to these and other similar cliches as nothing more than rose-tinted literations of the past; a cognitive side effect of life. Romanticizing collective memories aside, however, it would be a challenge to find anyone who could argue against the physical degradations that accompany aging. One needs only to search for 'photos of aging' to realize that such yearnings are perhaps nothing more than ourselves giving form to the personal struggle with the byproducts of life.
March 10, 2017
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Does pride raise the risk of falling?
Each year, the prestigious academic journal The BMJ releases a Christmas issue, putting together a series of more lighthearted studies. As part of this year's issue, scientists ask whether the biblical saying "pride comes before a fall" has any truth in it.
December 13, 2017
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Does sex help older brains to work better?
New research found that older adults who reported having sex at least once each week got better scores on certain cognitive tests than those who reported having sex only once per month or not at all.
June 23, 2017
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Drinking makes you older at the cellular level
The more alcohol that people drink, the more their cells appear to age. Researchers found that alcoholic patients had shortened telomere lengths, placing them at greater risk for age-related illnesses, such as cardiovascular disease, diabetes, cancer and dementia..
June 26, 2017
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Misc. - E

Easy-to-use omics toolkit sets the stage for new era of biology and precision medicine
Most complex diseases, such as obesity, longevity, and diabetes, are largely influenced by genetic factors. But at the same time, they are also modulated by environmental stimuli, such as diet and physical activity. This interaction between the environment and genetic makeup makes every human unique, and underpins the need for personalized medicine.
November 29, 2017
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Elder abuse rates found to be higher than previously estimated
Around 1 in 6 older people experience some form of abuse, a figure higher than previously estimated and predicted to rise as populations age worldwide.
June 14, 2017
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Even a Little Walking Can Lengthen Your Life
Less than the recommended 150 minutes a week still seemed to help, study found
October 19, 2017
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Even Non-Heart Surgery May Harm Your Heart
Older adults commonly suffer damage to heart cells during various types of surgery -- even non-heart-related surgeries -- and it can significantly raise their risk of dying from the procedure, a new study finds.
December 4, 2017
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Exercise prevents cellular aging by boosting mitochondria
It is common knowledge that exercise imparts a smorgasbord of health benefits. what is not yet understood is how physical activity manages to reduce aging on a cellular level. new research into mitochondria lifts the lid on the processes involved.
March 8, 2017
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Experts call for efforts to study elder abuse among veterans
Experts are calling on the Veterans Administration (VA) to promote research, clinical care, and education in the area of elder abuse, furthering the VA's mission of serving those who have served. Such efforts will benefit not only Veterans, but also the many older individuals in the general population who face mistreatment or harm, including physical, emotional or sexual abuse, along with neglect and financial exploitation.
November 9, 2017
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Misc. - F

Fall among elderly patients linked to higher risk for adverse events
More than half of elderly patients (age 65 and older) who visited an emergency department because of injuries sustained in a fall suffered adverse events -- including additional falls, hospitalization, and death -- within 6 months. The results of a study examining how risk factors predict recurrent falls and adverse events were published online yesterday in Annals of Emergency Medicine ("Revisit, Subsequent Hospitalization, Recurrent Fall and Death within 6 Months after a Fall among Elderly Emergency Department Patients").
July 6, 2017
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Forever Labs preserves young stem cells to prevent your older self from aging
Forever Labs, a startup in Y Combinator's latest batch, is preserving adult stem cells with the aim to help you live longer and healthier.
August 17, 2017
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Four cups of coffee a day may slash death risk
Coffee is one of the most popular beverages in the world, and a new study suggests the more we drink it, the better. A high intake of coffee seems to slash the risk of premature death, according to researchers.
August 29, 2017
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FSU researchers solve puzzle posed by family of rare premature aging disorders
New research from Florida State University is beginning to piece together the stubborn puzzle posed by a family of rare and debilitating premature aging disorders.
November 28, 2017
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Misc. - G

Gene therapy prevents age-related learning and memory problems in mice
Researchers from the Institute of Neurosciences at the Universitat Autònoma de Barcelona (INc-UAB) and the Vall d'Hebron Research Institute (VHIR) are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age-related learning and memory problems in mice.
October 31, 2017
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Georgia State researcher awarded NIH grant to explore pain management therapies for elderly
Dr. Anne Murphy, a biologist of Georgia State University, has received a five-year, $1.8 million grant from the National Institutes of Health (NIH), to investigate pain management therapies for people aged 65 or older.
February 8, 2017
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Grandma's insomnia might be a product of evolution
She's actually looking out for you.
July 14, 2017
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Good Sleep Does Get Tougher with Age
Review suggests many seniors struggle to get deep, restorative slumber, adding to health problems
April 5, 2017
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Governments could do more to develop transport policies that encourage older people's mobility
Governments across Europe could be doing more to develop transport policies that ensure those over the age of 65 remain active and mobile, according to a new study led by the University of Plymouth.
August 4, 2017
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Gut bacteria-produced compound may stave off aging
Researchers examined a class of chemical compounds called indoles and found that they have potential for extending vitality in our fellow mammals, mice. The findings could pave the way for a drug that could one day help humans to "live better for longer."
August 22, 2017
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Misc. - H

Having children may increase lifespan
The sleepless nights and stress that often accompany parenthood may not sound like the ingredients for a longer life, but according to a new study, having children could add years to a parent's lifespan.
March 14, 2017
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Having depression and heart disease could double death risk
While the mechanism behind the association is unknown, a new study finds that depression after being diagnosed with coronary artery disease doubles the risk of mortality.
July 31, 2017
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Healthy lifestyle may help reduce individual's disabled end-of-life period
New research published in the Journal of the American Geriatrics Society indicates that a healthy lifestyle may help reduce the duration of an individual's disabled period near the end of life.
September 1, 2017
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HELP program for older adults reduces hospital readmissions rates
The Hospital Elder Life Program, or HELP, is an evidence-based treatment plan developed in the 1990s to prevent hospitalized older adults from developing delirium (the medical term for sudden confusion). Delirium can cause people to be either aggressive and agitated or sleepy and inactive--sometimes even a combination of the two. Delirium is also the most common complication older adults experience after surgery.
November 9, 2017
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Herniated Disc Surgery Works for Seniors
Age is no reason to avoid the operation, Norwegian researchers report
June 16, 2017
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High levels of physical activity may slow aging at cellular level
Despite their best efforts, no scientist has ever come close to stopping humans from aging. Even anti-aging creams can't stop Old Father Time.
May 10, 2017
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Higher IQ in childhood is linked to a longer life
Higher intelligence (IQ) in childhood is associated with a lower lifetime risk of major causes of death, including heart disease, stroke, smoking related cancers, respiratory disease and dementia, finds a new study.
June 28, 2017
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Hormetic cognitive stress from exposure to technology may reduce age-related disease
It appears inevitable that technology is increasingly taking over our lives. However, it seems that it can also help us avoid aging and age-related disease, in a way that has not been described before.
May 19, 2017
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Misc. - I

IBM Working on Robotic Roommate that Helps Elderly Folks Stay Safe
while many people would love to live out the rest of their days happily ensconced in their home, living alone is not always the safest option for elderly folks. But because around-the-clock care – either in a nursing home, assisted living, or from a personal nurse – isn't always feasible, IBM is working on a robot designed to keep an eye on senior citizens and help them stay safe.
December 28, 2016
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Increased food availability during active season slows cellular aging in animals
Hibernation has long been considered the secret behind the relatively long lifespan of the edible dormouse. However, a team of researchers from Vetmeduni Vienna has now shown for the first time that high food availability during the active season in summer contributes to a long life. Increased food availability during this time allows the animals to slow their cellular aging.
September 2, 2016
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Innovative walking app could help older people stay fit and active
'Walking for Well-Being', a prototype app that makes it easy to plan less difficult, less demanding walking routes, could help people to stay fit, active and independent as they get older.
January 9, 2017
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It's not just what you eat, it's what's eating you
Restricting how much you eat without starving has been shown to robustly extend lifespan in more than 20 species of animals including primates. How this works is still unclear. A new study shows that it's not just what or how much you eat that matters. Smelling food in addition to consuming calories could influence the aging process. And, what's 'eating' you or more specifically your cells may provide clues to healthy aging.
August 2, 2017
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IU study finds homicide as top cause for potential years of life lost among black Americans
Homicide is the largest contributor to potential years of life lost among black Americans, according to a study published today and conducted by researchers at the Indiana University School of Public Health-Bloomington.
October 11, 2017
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Misc. - L

Life Expectancy Goes Up for Black Americans
But CDC report also found they're still more likely to die at an earlier age than whites
May 2, 2017
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IMB researchers unveil mystery of aging process
Researchers at the Institute of Molecular Biology (IMB) in Mainz have made a breakthrough in understanding the origin of the aging process. They have identified that genes belonging to a process called autophagy, which is one of the cells most critical survival processes, promote health and fitness in young worms but drive the process of aging later in life.
September 27, 2017
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'Loneliness Epidemic' Called a Major Public Health Threat
Social isolation tied to increased risk for premature death, research suggests
August 7, 2017
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Long-lived yeast mutants unlock clues to improve health and extend lifespan
Yeast -- it's more than just a fungus. It can also tell us a lot about growing older.
January 31, 2017
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Longevity in U.S.: Location, Location, Location
Study found life expectancy differed by as much as 20 years in different counties
May 8, 2017
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Low levels of simple chemical associated with aging, DNA damage
Treatment with a simple chemical restores DNA repair to aging mice.
March 24, 2017
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Misc. - M

Maternal stress during pregnancy could lead to premature biological ageing in offspring
The stress that some mothers experience during their pregnancies could influence the genetic makeup their babies are born with and, eventually, lead to premature biological ageing and associated age-related diseases. this is according to lead authors Tabea Send and Stephanie Witt of the Central Institute of Mental Health, University of Heidelberg in Germany. the study is published in in Springer Nature's journal Neuropsychopharmacology and focuses on a person's DNA sequences called telomeres, which are essential for cellular replication.
April 11, 2017
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Mayo Clinic experts move closer to realizing clinical potential of senolytic drugs on aging
Researchers are moving closer to realizing the clinical potential of drugs that have previously been shown to support healthy aging in animals. In a review article published online in the Journal of the American Geriatrics Society, Mayo Clinic aging experts say that, if proven to be effective and safe in humans, these drugs could be "transformative" by preventing or delaying chronic conditions as a group instead of one at a time.
September 4, 2017
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Mayo Clinic researchers discover three new senolytic drugs
Mayo Clinic researchers have uncovered three new agents to add to the emerging repertoire of drugs that aim to delay the onset of aging by targeting senescent cells - cells that contribute to frailty and other age-related conditions. a recent study of human cell cultures shows that the drugs, fisetin and two BCL-XL inhibitors - A1331852 and A1155463 - cleared senescent cells in vitro. Findings appear online in Aging.
March 9, 2017
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Mayo Clinic study reveals link between senescent cells and bone loss in mice
Mayo Clinic researchers have reported a causal link between senescent cells - the cells associated with aging and age-related disease - and bone loss in mice. Targeting these cells led to an increase in bone mass and strength.
August 21, 2017
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Medicxi launches $300m European late-stage life sciences fund backed by Google company
Verily joins Novartis and the European Investment Fund
June 19, 2017
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Methylation status of ten positions in genome correlates with all-cause mortality
Various chemical modifications in the genome determine whether genes are read or deactivated. Methyl labels in the DNA play a key role in this "epigenetic" regulation of gene activity. Life style and environmental factors influence the methylation in the genome. Scientists have already well documented links between the methylation status of specific positions in the genome and cancer as well as other diseases.
March 19, 2017
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Miniature Bioengineered Vessels to Study Progeria Therapies
Progeria is a rare but deadly disorder that is commonly known as an early aging disease, bringing forth conditions in children that are normally only reserved for older adults. To better study how to fight progeria, a disease that significantly affects the cardiovascular system, researchers at Duke University have developed a way to grow tiny blood vessels that behave very much like the blood vessels of patients with the disease.
August 16, 2017
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Monthly high dose of vitamin D lowers respiratory infections in older adults
In people over the age of 65, acute respiratory infections--such as the common cold, influenza, or pneumonia--can lead to potentially life-threatening complications.
January 5, 2017
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More doctors in the U.S. now focus on nursing home care, study finds
The number of doctors and advance practitioners in the United States who focus on nursing home care rose by more than a third between 2012 and 2015, according to a new study published today in JAMA from researchers at the Perelman School of Medicine at the University of Pennsylvania. Of all physicians and advance practitioners who do any work in nursing homes, 21 percent now specialize in nursing home care. The authors say the trend suggests the rise of a significant new specialty in medical practice, though how it will affect patient outcomes and continuity of care is yet to be seen.
November 29, 2017
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Moving every 30 minutes may help you live longer
Getting up and out of your seat every 30 minutes could help to reduce the harms of sedentary behavior, according to a new study.
September 12, 2017
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Mushrooms have high amounts of antioxidants that may help with anti-aging treatments
Mushrooms may contain unusually high amounts of two antioxidants that some scientists suggest could help fight aging and bolster health, according to a team of Penn State researchers.
November 9, 2017
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Misc. - N

National health collaborative efforts can help reduce infection rates in nursing homes
Each year, 150,000 U.S. nursing home residents will receive a urinary catheter--half of whom will develop a catheter-associated urinary tract infection (CAUTI). While 70 percent of facilities report having an infection preventionist (IP) on staff, many nursing home IPs often have limited time to advance their training on infection control.
December 5, 2017
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New crowdfunding campaign aims to develop, test novel photographic biomarkers of aging in mice
The Biogerontology Research Foundation announces the launch of a crowdfunding campaign, MouseAge, to develop and test photographic biomarkers of aging in mice in collaboration with scientists from Harvard University, University of Oxford, Youth Laboratories and Insilico Medicine. The project's aim is to develop novel biomarkers of aging in mice for the purposes of testing the effect of healthspan and lifespan-extending interventions.
August 31, 2017
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New findings could help better understand aging process and extend lifespan
Restricting how much you eat without starving has been shown to robustly extend lifespan in more than 20 species of animals including primates. How this works is still unclear. In a new study published in PLOS Genetics, neuroscientists from Florida Atlantic University show that it's not just what or how much you eat that matters. Smelling food in addition to consuming calories could influence the aging process. And, what's "eating" you or more specifically your cells may provide clues to healthy aging.
August 2, 2017
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New partnership uses artificial intelligence methods to develop solutions for preventing early aging
Center for Healthy Aging at the University of Copenhagen today announced a research collaboration with a company specializing in artificial intelligence (AI) to develop solutions for preventing early aging. The aim of this partnership is to develop medicines to prevent and cure a broad range of diseases associated with aging such as Alzheimer's, Parkinson's and cardiovascular diseases.
August 1, 2017
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New protein discovered in aging, cancer
A protein has been found to have a previously unknown role in the ageing of cells, according to an early study. the researchers hope that the findings could one day lead to new treatments for aging and early cancer.
March 7, 2017
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New research shows high and low levels of HDL cholesterol may increase risk of early death
Commonly touted as "good cholesterol" for helping to reduce risk of stroke and heart attack, both high and low levels of high-density lipoprotein (HDL) cholesterol may increase a person's risk of premature death, according to new research at Washington University School of Medicine in St. Louis and Veterans Affairs St. Louis Health Care System.
August 11, 2016
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Nursing homes move into the insurance business
Around the country, a handful of nursing home companies have begun selling their own private Medicare insurance policies, pledging close coordination and promising to give clinicians more authority to decide what treatments they will cover for each patient.
July 13, 2017
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Nutrition could be cost-effective treatment to improve health in malnourished older adults
As a majority of older adults have two or more chronic conditions, finding new ways to improve their health and decrease the cost of care is vital to helping them live healthier, longer lives. a new study found that malnourished older adults who were hospitalized with a heart or lung disease had an additional 8.5 months of estimated life expectancy when they received a specialized nutrition supplement, compared to a placebo group.
August 30, 2016
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Misc. - O

Obesity May Age your Brain
Being overweight or obese in middle age shrinks your brain, aging it by as much as 10 years, according to a new study.
August 09, 2016
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Older adults face elevated risk of death after pelvic fractures, study reveals
Adults older than 60 years face an increased risk of dying in the first 8 months following a pelvic fracture, new research indicates.
March 9, 2017
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Older hip fracture patients frequently use antidepressant and anti-anxiety drugs, study finds
In a recent study, older individuals who had fallen and broken a hip used antidepressant and anti-anxiety medications more frequently than the general older population.
March 8, 2017
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Operation of ancient biological clock uncovered
The operation of one of the oldest biological clocks in the world has, which is crucial for life on earth as we know it, has now been discovered by scientists. the researchers applied a new combination of cutting-edge research techniques. they discovered how the biological clock in cyanobacteria works in detail. Important to understand life, because cyanobacteria were the first organisms on earth producing oxygen via photosynthesis.
March 16, 2017
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Osteoporosis: Potential new drug target uncovered
Researchers have uncovered a new cause for osteoporosis in the body's so-called senescent cells. By targeting these cells with anti-aging drugs, the findings could change therapeutic approaches for the treatment of age-related bone loss.
August 21, 2017
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Our chromosomes also wrinkle with age, research shows
Grey hair, wisdom, and wrinkles on our skin mark us as we age, but it's the more subtle changes beneath the surface that make us old. Now, researchers have discovered that our chromosomes also wrinkle with age, changing how our immune system renews itself.
October 31, 2017
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Misc. - P

Paradox of pills: Tablet 'overload' may be causing harm and putting lives at risk, warn researchers
Around three million people take multiple medicines, but no reliable systems exist to help patients and carers manage their pills. When medication management goes wrong, particularly with older people, the effect can be dreadful for everyone involved. A novel study linking the experiences of patients, carers and practitioners with a review of the scientific evidence, aims to find ways to improve medication management and the quality of life of older people and their carers.
June 22, 2017
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Parenthood may boost longevity, study suggests
Being a parent could increase the likelihood of living longer once people are in their later years, say researchers.
March 16, 2017
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Patient mortality could be predicted through computer analysis of organs
Using a computer to analyze CT images of patients' organs, researchers were able to predict their 5-year mortality with almost 70 percent accuracy.
June 5, 2017
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Poor smell linked to higher risk of early mortality
In a study of adults aged 40 to 90 years who were followed for 10 years, poor smell was linked with an increased risk of dying.
March 22, 2017
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Prolonged sitting and frailty a deadly combination
High levels of sedentary behavior may increase the risk of death for frail adults aged 50 and older who have low levels of physical activity, a new study suggests.
August 21, 2017
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Prolonged sitting and TV watching 'dangerous' for seniors
New research suggests that increased sedentary behavior, combined with low physical activity and increased TV watching time, drastically raises the risk of walking disability among seniors.
August 30, 2017
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Protein in umbilical cord blood may restore the aging brain
Umbilical cord blood could hold the key to restoring the learning and memory ability that declines with age, find researchers at the Stanford University School of Medicine in California. Providing older mice with injections of human umbilical cord blood revitalized their brain function. the researchers suggest that it is likely that similar beneficial effects would be seen in humans.
April 20, 2017
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Protein that regulates expression of many genes increases lifespan of baker's yeast
To understand and control aging is the aspiration of many scientists. Researchers at the Biozentrum of the University of Basel have now discovered that the protein Gcn4 decreases protein synthesis and extends the life of yeast cells. Understanding how individual genes affect lifespan opens new ways to control the aging process and the occurrence of aging-related diseases.
September 6, 2017
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Prune consumption may prevent bone mineral density loss in older population
As the demographic shift to an older population continues, a growing number of men and women will be diagnosed with osteoporosis. In addition to existing drug therapies, certain lifestyle and nutritional factors are known to reduce its risk.
January 20, 2017
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Misc. - R

Research offers new clues to prolong lifespan of the body's disease-fighting NK cells
A team of researchers from Australia and France have uncovered new insights into how to prolong the lifespan of the body's disease-fighting natural killer (NK) cells.
January 17, 2017
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Research shows how cutting calories can slow aging process
There's a multi-billion-dollar industry devoted to products that fight signs of aging, but moisturizers only go skin deep. Aging occurs deeper -- at a cellular level -- and scientists have found that eating less can slow this cellular process.
February 13, 2017
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Research suggests that resistance training may prevent age-related tendon problems
A study published online in The FASEB Journal suggests that resistance training may prevent age-related tendon problems, such as ruptures and tendinopathies. In the report, scientists used different groups of sedentary and resistance-trained rats to reveal that the tendons of trained rats showed fewer signs of age-related damage than their sedentary counterparts. If this proves true in humans, it would provide further evidence that resistance training can have beneficial effects throughout one's lifespan.
October 4, 2017
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Researchers analyze molecular processes that influence aging
Understanding the factors that control aging has been one of humanity's endless pursuits, from the mystical fountain of youth to practical healthful regimens to prolong life expectancy.
November 2, 2017
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Researchers develop new assessment to predict risk of falls in long-term care patients
Researchers from Hebrew SeniorLife's Institute for Aging Research have developed and validated a new assessment to predict the risk of falls in long-term care patients. The study on the assessment titled "Fracture Risk Assessment in Long-term Care (FRAiL)" was published today in the Journal of Gerontology Medical Science.
August 31, 2017
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Researchers discover how protein aggregation triggers aging
Researchers at the universities of Cologne and Bonn uncover the link between protein aggregation and aging
April 21, 2017
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Researchers identify new rare genetic variants linked to extreme longevity
The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations.
April 25, 2017
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Researchers in disagreement over maximum lifespan data
In October 2016, research published in Nature claimed that since the mid 1990s, the age of the oldest person has not increased. But others have been critical of the high-profile paper, leading to a series of exchanges of opinion among the authors and their critics in Nature this week.
June 29, 2017
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Researchers use artificial intelligence to predict patient's lifespan
A computer's ability to predict a patient's lifespan simply by looking at images of their organs is a step closer to becoming a reality, thanks to new research led by the University of Adelaide.
June 1, 2017
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Researchers uncover 16 genetic markers linked to decreased lifespan
The answer to how long each of us will live is partly encoded in our genome. Researchers have identified 16 genetic markers associated with a decreased lifespan, including 14 new to science. This is the largest set of markers of lifespan uncovered to date. About 10% of the population carries some configurations of these markers that shorten their life by over a year compared with the population average. Spearheaded by scientists from the SIB Swiss Institute of Bioinformatics, the Lausanne University Hospital (CHUV), the University of Lausanne and the EPFL, the study provides a powerful computational framework to uncover the genetics of our time of death, and ultimately of any disease.
July 27, 2017
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Retirement's revolving door: Why some workers can't call it quits
In his view, Tim Franson utterly failed at retirement.
December 11, 2017
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Review focuses on benefits of mindfulness in aging populations
As mindfulness practices rise in popularity and evidence of their worth continues to accumulate, those who work with aging populations are looking to use the techniques to boost cognitive, emotional and physiological health.
February 21, 2017
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Risk of oversharing in conversation increases with age, study says
The risk of oversharing in conversation -- or providing a listener with too much irrelevant detail - increases as we age, research suggests.
November 2, 2017
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Misc. - S

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills
if you're 65 or older and taking more than four medications, resolve to talk to your doctor about doing a new Year's triage to make sure too many pills aren't making you sick, advises Milta Little, D.O., associate professor of geriatrics at Saint Louis University.
December 25, 2016
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Scientists announce landmark database of lifespan-extending drugs and compounds
Scientists from the Biogerontology Research Foundation (BGRF) and University of Liverpool have announced a landmark database of lifespan-extending drugs and compounds called DrugAge. the database has 418 compounds, curated from studies spanning 27 different model organisms including yeast, worms, flies and mice. It is the largest such database in the world at this time.
March 14, 2017
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Scientists decipher mechanisms underlying the biology of aging
Multi-pronged approach reveals a delicate balance required for longevity
November 2, 2017
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Scientists discover how insulin-producing cells show differences in age
Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets. Using newly identified cellular markers of aging, Joslin Diabetes Center scientists now have shown that this diversity may be driven at least in part by differently aged beta cell populations within the pancreas.
April 12, 2017
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Scientists rejuvenate aging cells from children with progeria
Using new technology, researchers from Texas found that they could reverse many markers of aging in cells from children with progeria, a rare genetic disease that causes rapid aging and early death.
August 1, 2017
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Scientists take closer look at biological processes to unlock secrets of youth
Humans have been looking for ways to cheat death for centuries. and while we've succeeded in extending our life span, many people suffer ill health in their later years. now researchers have pivoted to study ways to improve our "health span" to allow us to enjoy our longevity.
March 8, 2017
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SENIOR trial: Shorter DAPT combined with Synergy stent superior to BMS in elderly patients
Elderly patients undergoing PCI often receive bare-metal stents (BMS) instead of drug-eluting stents (DES) to shorten the duration of dual antiplatelet therapy (DAPT) and reduce bleeding risk. However, results from the SENIOR trial found that compared with BMS, shorter DAPT combined with the Synergy bioabsorbable polymer DES leads to less adverse events without increasing bleeding risk.
November 2, 2017
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Seniors May Get a Boost from Green Spaces
Small study detects positive brain changes from urban oases
April 17, 2017
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Seniors who live with their abusers often suffer recurrent abuse
Older adults who have been hospitalized for injuries from an assault are more likely to experience subsequent physical abuse if they are female, widowed, diagnosed with dementia, or return home to live with the perpetrator, according to a new study.
May 9, 2017
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Seniors May Have Trouble Managing Money, Medicines
By 85, many could use a hand, study finds
April 28, 2017
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Seniors' well-being may depend more on psychological factors than physical ones
Old age often comes with physical discomfort and health problems. But new research points to psychosocial, not physical, factors as the main culprit for lower well-being in later life.
July 10, 2017
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Simple physical activities may help prolong life for older women, study finds
Folding your laundry or doing the dishes might not be the most enjoyable parts of your day. But simple activities like these may help prolong your life, according to the findings of a new study in older women led by the University at Buffalo.
November 16, 2017
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Sitting Could Be Big Health Risk for Frail Folks
Being sedentary not linked to early death in people who are generally healthy, study finds
August 21, 2017
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Skin aging could be delayed with a common antioxidant
For many people, declining skin health is one of most loathsome effects of getting older. As we age, our skin loses its elasticity, becomes thinner and drier, and its ability to repair dwindles. A new study, however, has uncovered an antioxidant that could delay skin aging.
May 31, 2017
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Sorting out what happens in the aging brains of bilinguals
We really need long-term research on the topic.
February 2, 2017
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Specific area of the brain helps keep the body young
Your hypothalamus might be the actual fountain of youth.
July 27, 2017
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Stem cells in the brain found to influence aging in mice
A study conducted by a team of researchers led by Dongsheng Cai at the Albert Einstein College of Medicine, New York, finds that injecting extra stem cells into the hypothalamus in the brain of mice slows down the aging process.
July 27, 2017
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Study finds premature death rates diverge in the United States by race and ethnicity
Premature death rates have declined in the United States among Hispanics, blacks, and Asian/Pacific Islanders (APIs) – in line with trends in Canada and the United Kingdom – but increased among whites and American Indian/Alaska Natives (AI/ANs), according to a comprehensive study of premature death rates for the entire U.S. population from 1999 to 2014.
January 26, 2017
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Study provides evidence that virtual reality could help prevent falls in elderly people
Every year, falls lead to hospitalization or death for hundreds of thousands of elderly Americans. Standard clinical techniques generally cannot diagnose balance impairments before they lead to falls. But researchers from the University of North Carolina at Chapel Hill and North Carolina State University have found evidence that virtual reality (VR) could be a big help -- not only for detecting balance impairments early, but perhaps also for reversing those impairments and preventing falls.
April 20, 2017
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Study reveals high use of medications for mental illness in Norwegian nursing homes
For the first time ever, researchers have looked at the long-term use of psychiatric medication in Norwegian nursing homes. Psychiatric drugs are a collective term for medicines used to treat mental disorders, such as antipsychotics, anxiolytics (anxiety suppressants), antidepressants and sleeping pills.
July 7, 2017
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Study reveals increase in premature deaths of nursing home residents in Australia
The first comprehensive study of deaths in Australian nursing homes has been published today (29 May), revealing a more than 400 per cent increase in the incidence of premature and potentially preventable deaths of nursing home residents over the past decade.
May 29, 2017
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Study shows the aging brain has trouble generating brain waves required for deep sleep
Older people tend to experience less sleep, due to taking frequent trips to the bathroom, and losing the ability to create deep restorative sleep compared with young adults.
April 6, 2017
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Studying the nanomechanical properties of aging and cancerous cells using AFM
Can you please explain how you use AFM to study the nanomechanical properties of cells related to aging processes and cancer?
October 31, 2017
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Suicide Up in U.S., Rural America Hit Hardest
Men, working-age adults most at risk, CDC reports
October 6, 2017
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Misc. - T

Telomeres: What causes biological aging?
If you are wondering how your cells age, look no further than the ends of your chromosomes. Special structures called telomeres keep a close eye on the damage that accumulates in our cells and signal when it is time for them to retire.
August 2, 2017
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Testosterone Therapy May Have Benefits, Risks
while trials show it boosts bone density and lowers anemia risk, heart risks also seen
February 21, 2017
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The Lazarus phenomenon: When the 'dead' come back to life
Her heart had stopped beating and she was no longer breathing. Janina Kolkiewicz was declared dead. At 91 years old, she had lived a long life. But she was not about to stop living it. Eleven hours later, she awoke in the hospital mortuary with a craving for tea and pancakes. As inconceivable as it sounds, Kolkiewicz is just one of many people said to have "risen from the dead."
May 26, 2017
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These 5 Preventable Conditions Shorten Lives
Obesity steals the most years of all, researchers say
April 24, 2017
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These annual checkups help seniors not only survive but thrive
Bea Lipsky shuffled into her wellness coach's office one morning this fall and parked her walker by the wall. Lipsky, 89, had had a trying year, enduring a hernia operation and two emergency room visits for heart problems. She's losing her hearing, and recently gave up her dream of riding in a hot air balloon for her 90th birthday.
December 13, 2017
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They've still got bucket lists -- in their 90s
It is one thing to have a bucket list at any age. It is something else entirely to have a bucket list that sends you to college for the first time at 92 -- or that sends you on your maiden flight at the controls of a single-engine airplane at 97.
June 5, 2017
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Tick tock, stay ahead of the aging clock
Aging in humans (and animals) can be seen as either an inevitable process of wear and tear or as an inherent biological program by which the lifespan of each species is more or less predetermined. Recent research has shown that DNA methylation, an epigenetic modification which alters how DNA is read and expressed without altering the underlying sequence, can show age-related changes.
April 12, 2017
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Today's Middle-Aged in Worse Health Than Ancestors
50-somethings will face more challenges as retirement nears, study suggests
October 6, 2017
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Misc. - U

Under 2 hours of walking per week may considerably prolong life
A new study published in the American Journal of Preventive Medicine suggests that even a little walking can significantly reduce mortality risk, compared with inactivity.
October 19, 2017
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Unexpected memory retrieval mechanism found in landmark study
A landmark study exploring a little-researched area of the hippocampus made an unexpected discovery about how memory is retrieved. The scientists found, surprisingly, that memory retrieval and memory formation depend on very distinct mechanisms.
August 21, 2017
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Urgent hospitalizations linked to increased rate of cognitive decline in older adults
Emergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at Rush University Medical Center. The results of their study suggest that hospitalization may be a more of a major risk factor for long-term cognitive decline in older adults than previously recognized.
July 17, 2017
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UZH leads Europe's largest research on aging.aspx
A total of 2157 men and women age 70 years and older participate in the study and were recruited from 7 University Centers in 5 European countries: 552 from Zurich, 253 from Basel, 201 from Geneva, 350 from Berlin, 200 from Innsbruck, 300 from Toulouse, and 301 from Coimbra.
November 20, 2017
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Misc. - V

Vasopressin: Water management and the biological clock
Water is the molecule of life; without it, none of us would be here. However, despite its importance, how the body manages water still holds some secrets. Innovative research in Canada generates new insight.
May 31, 2017
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Video Monitoring and Motion Detection Predicts Falls in Elderly
Simple falls are a serious danger for elderly folks, as they lead to fractured hips and other trauma that can seriously damage people's lifestyles. Being able to predict that a geriatric patient is particularly prone to losing balance can help to prevent injury. now the researchers at the University of Missouri have collected and processed an immense amount of information about the movement of seniors and looked how changes correlate with subsequent falls.
August 30, 2016
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Misc. - W

Waist Size, not Weight, May be Key to Life Span
Even those who aren't overweight are at risk of death if they've got a paunch, researchers report
April 24, 2017
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What happens to the brain as we age?
Brain aging is inevitable to some extent, but not uniform; it affects everyone, or every brain, differently. Slowing down brain aging or stopping it altogether would be the ultimate elixir to achieve eternal youth. Is brain aging a slippery slope that we need to accept? Or are there steps we can take to reduce the rate of decline?
August 29, 2017
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What's the 'SuperAgers' Mental Secret?
Some folks stay sharp into their 80s, 90s, and brain scans may show why
April 4, 2017
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Misc. - Y

Yoga May Boost Aging Brains
Changes seen in areas involved with attention and memory, but it's not yet clear if yoga is the cause
August 9, 2017
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Your daily coffee could help you live longer
If you're a regular coffee drinker, a new study might brighten your day. Researchers have found that consuming the popular beverage may increase longevity, and it doesn't even need to be caffeinated.
July 11, 2017
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