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146 Health - Parkinson's Disease Resources

Misc. - Numbers

'5-D protein fingerprinting' with nanopores could give insights into Alzheimer's, Parkinson's
In research that could one day lead to advances against neurodegenerative diseases like Alzheimer's and Parkinson's, University of Michigan engineering researchers have demonstrated a technique for precisely measuring the properties of individual protein molecules floating in a liquid.
January 17, 2017
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23andMe is finally allowed to tell you if you have the genes for Parkinson's
The Food and Drug Administration finally gave 23andMe a long sought-after green light today to sell to consumers genetic tests and their accompanying health risk reports for up to 10 diseases, including late-onset Alzheimer's and Parkinson's.
April 6, 2017
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23andMe wins FDA approval to give customers health risk info
The gene testing company can now tell US customers who use its home DNA kit whether they have a genetic risk for any of 10 diseases and conditions.
April 6, 2017
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Misc. - A

A cure for Parkinson's? Replacing damaged brain cells shows promise
Researchers may have brought us closer to a cure for Parkinson's disease, after finding a way to replace the brain cells destroyed by the disease.
April 11, 2017
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A Graphic Designer Rewrites Her Future with Parkinson's Disease
Today at Build, Microsoft's annual developer conference, chief executive officer Satya Nadella shared his vision for the future of technology. As part of the discussion, he emphasized the role that technology can play to empower people to achieve more and the importance of inclusive design to make sure technology leaves no one behind.
June 2, 2017
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Altmetric data analysis reveals how Parkinson's disease research affects the world
Scientists have published an analysis of Parkinson's disease research papers with the highest Altmetric Attention Scores. the publication is the first in a series aimed at utilizing Altmetric data to provide a more nuanced understanding of how the announcements of new medical discoveries affect the wide-range of disease-specific stakeholders including researchers, funders, care providers, and patients.
February 13, 2017
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Antibiotic doxycycline may offer hope for treatment of Parkinson's disease
Recent study suggests that doxycycline can be prescribed at lower doses for the treatment of Parkinson's disease
May 3, 2017
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Antidepressants could delay Parkinson's progression
A 50-year-old antidepressant could stop the buildup of a brain protein involved in Parkinson's disease, marking a discovery that could bring us closer to slowing the condition.
September 6, 2017
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Altered bacterial communities in the gut could be an indicator for Parkinson's disease
In search of a biomarker
August 29, 2017
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Autoimmunity may have role in Parkinson's disease
For the first time, scientists have found evidence that autoimmunity may have a role in Parkinson's disease. They found that fragments of the protein that builds up in the dopamine cells of the brains of people with Parkinson's trigger an immune response that kills the cells.
June 21, 2017
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Misc. - B

Bacterial community in the gut of Parkinson's patients differs from that of healthy people
Parkinson's disease is an insidious disease: by the time it manifests as the typical motor dysfunctions such as tremors or muscle rigidity, portions of the brain have already been irreversibly destroyed. By this stage, the disease will have often begun already decades earlier. In search of an early portent of the disease, researchers led by Prof. Paul Wilmes, head of the Eco-Systems Biology Group at the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg, may now have found one in the gut: they have shown that the bacterial community in the gut of Parkinson's patients differs from that of healthy people even at a very early stage of the disease.
August 29, 2017
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Big trash pickup for cells
Cells are garbage pickers, carefully selecting the trash they want to keep or discard
August 1, 2016
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Biofeedback System for Parkinson's Rehab
Researchers at the University of Houston have developed wearable technology to assist Parkinson's patients to perform rehabilitation exercises in their own home.
August 4, 2017
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Biomarkers for cognitive impairment in Parkinson's revealed
Parkinson's disease affects about half a million people in the United States. New research identifies biomarkers that could predict the cognitive impairment typical of this neurodegenerative disease.
May 18, 2017
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Bowel cancer medication could help treat patients with early-onset Parkinson's disease, study suggests
People with certain forms of early-onset Parkinson's disease could potentially benefit from taking a medication used to treat certain forms of cancer, according to new research by University of Leicester scientists and funded by the Medical Research Council.
March 14, 2017
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Brain disconnections in Parkinson's patients might lead to visual hallucination, study says
A new study published in the online journal Radiology suggested that disconnections in the areas of the brain, which are involved in attention and visual processing might lead to visual hallucinations in patients with Parkinson's disease.
September 27, 2017
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Brain disconnections may contribute to Parkinson's hallucinations
Disconnections of brain areas involved in attention and visual processing may contribute to visual hallucinations in individuals with Parkinson's disease, according to a new study. The disconnected brain areas seen on functional MRI may be valuable in predicting the development of visual hallucinations in patients with Parkinson's disease.
September 27, 2017
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Brain Scan May Explain Parkinson's Hallucinations
Scans showed areas with decreased connectivity
September 28, 2017
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Brain's immune cells linked to Alzheimer's, Parkinson's, schizophrenia
Scientists conducted a vast microglia survey, revealing links to neurodegenerative diseases and psychiatric illnesses.
May 31, 2017
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Breakthrough in production of dopamine neurons for Parkinson's disease
The first transplantation of stem cells in patients with Parkinson's disease is almost within reach, say investigators. However, it remains a challenge for researchers to control stem cells accurately in the lab in order to achieve successful and functional stem cell therapies for patients.
October 28, 2016
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Build 2017: Microsoft's 'Project Emma' is a wearable for Parkinson's disease sufferers
Today at Build 2017, Microsoft unveiled many cool new technologies, but there was one particular announcement that truly touched the hearts of many in attendance. Called "Emma," it is a wrist wearable that can help people suffering with Parkinson's disease.
May 10, 2017
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Misc. - C

Can coffee help to treat Parkinson's? Not likely
In 2012, Canadian researchers brought some welcome news for patients with Parkinson's disease: caffeine may ease symptoms of the disease. But 5 years on, the research team has revealed that the coffee compound may not be so beneficial after all.
September 28, 2017
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Can This New Non-Invasive Brain Stimulation Cure Parkinson's?
MIT researchers developed a new form of non-invasive deep brain stimulation that promises to be less risky, less expensive, and more accessible to patients.
June 8, 2017
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Cell disposal faults could contribute to Parkinson's, study finds
A fault with the natural waste disposal system that helps to keep our brain cell 'batteries' healthy may contribute to neurodegenerative disease, a new study has found.
January 24, 2017
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Coffee Doesn't Help Parkinson's Motor Disorders
Caffeine has no impact, says long-term trial that reverses earlier findings
September 28, 2017
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Correct connections are crucial
Individualizing deep brain stimulation in patients with Parkinson's disease
June 23, 2017
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Could Parkinson's disease start in the gut?
Parkinson's disease may start in the gut and spread to the brain via the vagus nerve, according to a study. the vagus nerve extends from the brainstem to the abdomen and controls unconscious body processes like heart rate and food digestion.
April 26, 2017
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CRISPR tech leads to new screening tool for Parkinson's disease
A team of researchers is using breakthrough gene-editing technology to develop a new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system. The technology allows scientists in the lab to 'light up' and then monitor a brain protein called alpha-synuclein that has been associated with Parkinson's.
June 5, 2017
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Misc. - D

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases
Rutgers scientists say neurodegenerative diseases like Alzheimer's and Parkinson's may be linked to defective brain cells disposing toxic proteins that make neighboring cells sick.
February 10, 2017
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Dementia not prevented with vitamin E, selenium, study finds
An ample body of research has shown that oxidative stress plays a key role in the development of neurodegenerative disorders such as Alzheimer's and Parkinson's disease. as a result, antioxidant supplements have been proposed as preventive measures against dementia. a new trial, however, tests the effect of vitamin E and selenium on aging men and finds no evidence that they have therapeutic value.
March 19, 2017
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Diabetes drug cuts Parkinson's risk by 28 percent, study finds
A class of drugs currently used to treat diabetes could lower the risk of developing Parkinson's, a new study reveals, offering hope of new prevention and treatment strategies for the disease.
September 28, 2017
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Diabetes drug shows promise as Parkinson's treatment
A drug commonly used to treat diabetes could help people living with Parkinson's disease, say researchers.
August 7, 2017
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Diabetes drug slows experimental Parkinson's disease progression, human trials to begin next year
A new investigational drug originally developed for type 2 Diabetes is being readied for human clinical trials in search of the world's first treatment to impede the progression of Parkinson's disease following publication of new research.
December 6, 2016
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Diabetes shot boosts motor function for patients with Parkinson's
The results of a Parkinson's disease clinical trial suggest that the type 2 diabetes drug exenatide may work as a treatment that can slow or even stop the disease. Patients who injected the drug every week for 48 weeks performed better in movement tests than those who injected a placebo.
August 4, 2017
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Discovery of genetic 'switch' could help to prevent symptoms of Parkinson's disease
A genetic 'switch' has been discovered, which could help to prevent or delay the symptoms of Parkinson's disease, report scientists.
February 17, 2017
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DNA 'barcoding' allows rapid testing of nanoparticles for therapeutic delivery
Using tiny snippets of DNA as 'barcodes,' researchers have developed a new technique for rapidly screening the ability of nanoparticles to selectively deliver therapeutic genes to specific organs of the body. the technique could accelerate the development and use of gene therapies for such killers as heart disease, cancer and Parkinson's disease.
February 7, 2017
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Drugs targeting the beta2-adrenoreceptor linked to Parkinson's disease
Researchers want to prevent alpha-synuclein from accumulating in the brain. To do so, the team searched for drugs that turn down alpha-synuclein production. They then tested the drugs in mice and stem cells and studied in data from the health records of millions of people living in Norway. The results of their efforts, point to a new drug development path for PD.
August 31, 2017
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Misc. - E

Early Parkinson's May Prompt Vision Problems
Changes in sight could signal disease a decade before motor symptoms surface, study suggests
July 11, 2017
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Emory scientists show how same enzyme spurs Alzheimer's and Parkinson's disease
Alzheimer's disease and Parkinson's disease are not the same. They affect different regions of the brain and have distinct genetic and environmental risk factors.
July 4, 2017
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Exercise May be Real Medicine for Parkinson's
Physical activity helps improve gait and balance, research review finds
December 22, 2016
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Misc. - G

Gene mutation appears to increase risk of Parkinson's disease in Caucasians
A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research from Iowa State University. the effect is particularly dramatic for people under age 50.
November 28, 2016
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Gene mutation linked to early onset of Parkinson's disease in caucasians
A defect in a gene that produces dopamine in the brain appears to accelerate the onset of Parkinson's disease, according to new research. the effect is particularly dramatic for young-to-middle-age adults.
November 28, 2016
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Genetic variants linked to higher BMI may be protective against Parkinson disease
Genetic variants linked to higher body mass index (BMI) are associated with lower risk of Parkinson disease, according to a new study.
June 13, 2017
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Gut microbe mix may spark Parkinson's
In mice, brain inflammation, motor problems linked to intestinal bacteria
December 1, 2016
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Gut microbes promote motor deficits in a mouse model of Parkinson's disease
Gut microbes may play a critical role in the development of Parkinson's-like movement disorders in genetically predisposed mice, researchers report. Antibiotic treatment reduced motor deficits and molecular hallmarks of Parkinson's disease in a mouse model, whereas transplantation of gut microbes from patients with Parkinson's disease exacerbated symptoms in these mice. the findings could lead to new treatment strategies for the second most common neurodegenerative disease in the United States.
December 1, 2016
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Misc. - H

Hand-grip test can indicate decline in physical function of Parkinson's patients
A basic hand-grip test has proven to be a reliable tool to monitor the decline of patients with Parkinson's diseases, say investigators.
February 1, 2017
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Hand-grip test proves to be easy, reliable way to examine muscle strength decline in PD patients
UBC researchers Jenn Jakobi and Gareth Jones, both Health and Exercise Sciences professors at UBC's Okanagan campus, recently completed a study that examined the methods used to monitor the progressive advancement of Parkinson's disease (PD)--a degenerative disease that affects the central nervous system.
February 1, 2017
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How receptors for medicines work inside cells
The human genome encodes hundreds of G protein-coupled receptors (GPCRs). These form the largest group of receptors through which hormones and neurotransmitters exert their functions on our cells. Therefore, they are of highest importance as drug targets: around half of all prescribed drugs act on these receptors - and thus GPCRs help in the treatment of widespread diseases such as hypertension, asthma or Parkinson.
September 5, 2017
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Misc. - I

Immune system may mount an attack in Parkinson's disease
NIH-funded study suggests role for specific immune cells in brain disease.
July 27, 2017
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Immune system may wage a battle in Parkinson's disease
A new study suggests that T cells, which help the body's immune system recognize friend from foe, may play an important role in Parkinson's disease (PD). The study, published in the journal Nature, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
July 27, 2017
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Is It Parkinson's Disease? Blood Test Might Tell
But new technique needs more study, researchers say
February 8, 2017
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Misc. - L

Large-scale production of living brain cells enables entirely new research
Important pieces of the puzzle to understand what drives diseases such as Alzheimer's and Parkinson's are still missing today. One crucial obstacle for researchers is that it is impossible to examine a living brain cell in someone who is affected by the disease. With the help of a new method for cell conversion, researchers have found a way to produce diseased, aging brain cells on a large scale in a cell culture dish.
June 26, 2017
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Large-scale production of living brain cells enables entirely new research
Important pieces of the puzzle to understand what drives diseases such as Alzheimer's and Parkinson's are still missing today. One crucial obstacle for researchers is that it is impossible to examine a living brain cell in someone who is affected by the disease.
June 26, 2017
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Life-extending protein could treat Alzheimer's and Parkinson's
New research has shown that a naturally occurring protein can improve cognition in mice with Alzheimer's and Parkinson's disease-like characteristics. The findings open up a new therapeutic avenue for treating these neurodegenerative illnesses.
August 8, 2017
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Link between microbiome in the gut, Parkinson's discovered
Parkinson's disease, and medications to treat Parkinson's, have distinct effects on the composition of the trillions of bacteria that make up the gut microbiome, new research shows.
March 2, 2017
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Link between Parkinson's and melanoma runs both ways
A study published this week in Mayo Clinic Proceedings confirms that Parkinson's disease can, perhaps surprisingly, increase the risk of melanoma. The researchers also show that the link is a two-way relationship, with melanoma also suspected to increase the risk of Parkinson's.
July 4, 2017
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Low-fat dairy intake may raise Parkinson's risk
Low-fat dairy is often seen as a healthful alternative to the full-fat kind. But according to a new study, consuming higher amounts of low-fat dairy may raise the risk of Parkinson's disease.
June 8, 2017
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Misc. - M

Making brain implants smaller could eliminate scarring, extend life of devices
Many diseases, including Parkinson's disease, can be treated with electrical stimulation from an electrode implanted in the brain. However, the electrodes can produce scarring, which diminishes their effectiveness and can necessitate additional surgeries to replace them.
May 16, 2017
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Making brain implants smaller could prolong their lifespan
Thin fibers could be used to deliver drugs or electrical stimulation, with less damage to the brain
May 16, 2017
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Mayo Clinic study: Patients with Parkinson's have higher risk of melanoma and vice versa
People with the movement disorder Parkinson's disease have a much higher risk of the skin cancer melanoma, and vice versa, a Mayo Clinic study finds. While further research is needed into the connection, physicians treating one disease should be vigilant for signs of the other and counsel those patients about risk, the authors say.
July 4, 2017
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Mechanisms behind sensory deficits in Parkinson's disease
Although Parkinson's disease is often associated with motor symptoms such as stiffness, poor balance and trembling, the first symptoms are often sensory and include a reduced sense of touch and smell. In a study on mice, researchers have now been able to identify neural circuits and mechanisms behind this loss of sensory perception. The study may open avenues to methods of earlier diagnosis.
May 18, 2017
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Microsoft's Emma watch could help people with Parkinson's
Sometimes technology is used to really help people's lives.
May 11, 2017
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Mitochondrial lipids as potential targets in early onset Parkinson's disease
A team of researchers has identified an underlying mechanism in early onset Parkinson's. Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells' mitochondria, organelles that produce energy. they demonstrated that reducing the effects of the protein FASN influences the mitochondria, leading to increased cardiolipin levels and reduced Parkinson's symptoms. These results could pave the way to therapies for Parkinson's disease that target lipids.
February 10, 2017
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Monkeys with Parkinson's disease benefit from human stem cells
Transplantation of neurons made from induced pluripotent stem cells show long-term benefit in monkeys with Parkinson's disease
August 30, 2017
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More brain activity is not always better when it comes to memory, attention
Potential new ways of understanding the cause of cognitive impairments, such as problems with memory and attention, in brain disorders including schizophrenia and Alzheimer's are under the spotlight in a new research review.
June 15, 2017
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MPA approves Renishaw study into chronic drug delivery system in Parkinson's patients
The Medicines Agency of Sweden, MPA, has authorised Herantis Pharma Plc and Renishaw plc's randomised, placebo-controlled Phase 1-2 clinical study, for the investigation of Cerebral Dopamine Neurotrophic Factor (CDNF) and Renishaw's chronic drug delivery system, in Parkinson's patients.
April 4, 2017
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Misc. - N

Neuronal targets to restore movement in Parkinson's disease model
By using optogenetics to control neurons in the basal ganglia, researchers achieve effects that last longer than deep brain stimulation
May 8, 2017
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New antibodies target protein structures common to several neurological diseases
A new kind of antibody targets a feature shared by proteins thought to cause the most damage in Alzheimer's disease, Parkinson's disease, and related conditions, creating potential for a unified treatment approach.
August 29, 2017
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New brain scan could act as diagnostic tool in Parkinson's
A type of brain scan could act as a diagnostic tool in Parkinson's according to a new study published in the scientific journal Radiology.
December 9, 2016
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New clinical study to test promising Diabetes drug in people with MND
Could a Diabetes drug be used for Motor Neurone Disease?
March 10, 2017
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New device uses AI algorithm to monitor sleep with radio waves
More than 50 million Americans suffer from sleep disorders, and diseases including Parkinson's and Alzheimer's can also disrupt sleep. Diagnosing and monitoring these conditions usually requires attaching electrodes and a variety of other sensors to patients, which can further disrupt their sleep.
August 7, 2017
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New drug may limit disease progression, provide better symptom relief to Parkinson's patients
Researchers at Binghamton University have developed a new drug that may limit the progression of Parkinson's disease while providing better symptom relief to potentially hundreds of thousands of people with the disease.
July 31, 2017
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New drug target for Parkinson's disease found
A new study has found an enzyme that drives neurotoxicity in both Alzheimer's and Parkinson's disease. Blocking the action of this enzyme may prevent these conditions from developing, so the research may have found a new drug target.
July 4, 2017
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New partnership uses artificial intelligence methods to develop solutions for preventing early aging
Center for Healthy Aging at the University of Copenhagen today announced a research collaboration with a company specializing in artificial intelligence (AI) to develop solutions for preventing early aging. The aim of this partnership is to develop medicines to prevent and cure a broad range of diseases associated with aging such as Alzheimer's, Parkinson's and cardiovascular diseases.
August 1, 2017
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New research reveals surprising culprit involved in self-destruction of axons
In many neurodegenerative conditions -- Parkinson's disease, amyotrophic lateral sclerosis (ALS) and peripheral neuropathy among them -- an early defect is the loss of axons, the wiring of the nervous system. When axons are lost, nerve cells can't communicate as they should, and nervous system function is impaired. In peripheral neuropathy in particular, and perhaps other diseases, sick axons trigger a self-destruct program.
March 24, 2017
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New smart gloves to monitor Parkinson's disease patients
Prescribing a medication plan for a patient with Parkinson's disease is a big challenge for doctors, but now a biomedical engineering professor and his students are making great strides in solving that problem with their groundbreaking research.
October 21, 2016
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New technique scours the genome for genes that combat disease
Biological engineers identify genes that protect against protein linked to Parkinson's disease.
October 12, 2017
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New technology to manipulate cells could one day help treat Parkinson's, arthritis, other diseases
A groundbreaking advancement in materials from Northwestern University could potentially help patients requiring stem cell therapies for spinal cord injuries, stroke, Parkinson's disease, Alzheimer's disease, arthritic joints or any other condition requiring tissue regeneration, according to a new study.
July 10, 2017
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Nintendo Wii Now Used to Improve Lives of Parkinson's Patients
Researchers from Purdue University, Indiana University, and the University of Calgary have developed and are testing a set of video games to help improve the everyday lives of people with Parkinson's disease. The team relied on a Nintendo Wii video game platform coupled with the Wii Balance Board to run games in which a player moves a smiley face toward different targets on the screen.
September 26, 2017
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NNI, NTU collaborate to revolutionize diagnosis and treatment of neurological conditions
The National Neuroscience Institute (NNI) and Nanyang Technological University, Singapore (NTU Singapore) are collaborating to develop innovative technologies to better diagnose and treat patients with neurological conditions such as Parkinson's disease and brain injuries.
August 21, 2017
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Non-invasive Deep Brain Stimulation via Interfering High Frequency Signals
Researchers at MIT have developed a new technique to stimulate deep brain regions without the need for invasive implants. Currently, clinicians perform deep brain stimulation by placing electrodes into the brain to stimulate specific areas. As the therapy is so invasive, only patients with serious conditions like Parkinson's disease undergo treatment. The MIT scientists have developed a way to stimulate deep brain regions using electrodes on the scalp, which could potentially revolutionize the way the procedure is performed.
June 2, 2017
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Novel diagnostic approach could pave way for earlier detection of Parkinson's disease
Hebrew University doctoral student Suaad Abd-Elhadi has won a Kaye Innovation Award for her work on a new diagnostic approach that could pave the way for early diagnosis of one of the most common and debilitating neurodegenerative disorders.
July 6, 2017
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Novel mechanism identified to protect the brain from many neurodegenerative conditions
Scientists at Case Western Reserve University School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer's disease, and Parkinson's disease.
March 8, 2016
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Misc. - O

On the trail of Parkinson's disease
Chemists from Konstanz prove what happens when selective mutations occur to alpha-synuclein protein
March 24, 2017
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Misc. - P

Parkinson's breakthrough: New disease-causing mechanism found
A new study led by scientists in South Korea and Singapore "overturns three decades of consensus" on what causes Parkinson's disease symptoms.
October 2, 2017
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Parkinson's disease involves degeneration of the olfactory system
Scientists discover the anatomical link for the loss of smell in Parkinson's disease.
September 28, 2017
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Parkinson's disease may begin in the gut
Around half a million people in the United States are affected by Parkinson's disease, a neurodegenerative disorder. new research published in Neurology reveals that the gut may play a role in the disease and, furthermore, may be where Parkinson's disease begins.
April 27, 2017
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Parkinson's in a dish: Researchers reproduce brain oscillations
Breakthrough could speed the development of new Parkinson's treatments
May 3, 2017
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Parkinson's is partly an autoimmune disease, study finds
First direct evidence that abnormal protein in Parkinson's disease triggers immune response
June 21, 2017
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Parkinson's risk may be higher with hepatitis virus infection
Individuals infected with hepatitis B or C viruses may have a significantly greater risk of developing Parkinson's disease, new research suggests.
March 30, 2017
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Parkinson's severity assessed through drawing
Researchers combined measurements of drawing speed and pen pressure to diagnose Parkinson's disease severity
September 6, 2017
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Parkinson's: Asthma drugs may cut risk by a third
A research team from the University of Bergen in Norway, in collaboration with scientists at Harvard University in Cambridge, MA, examined the effect of 1,000 different medications to see which ones may lower or increase the risk of Parkinson's disease.
September 1, 2017
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Parkinson's: Sniff test could predict risk up to a decade earlier
A sniff test could one day predict the risk of Parkinson's up to 10 years before diagnosis, researchers suggest, after linking a poor sense of smell in later life with increased risk of the disease.
September 12, 2017
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Parkinson's: Stem cells restore nerve function in monkeys
Using stem cells, scientists have managed to restore nerve function in monkeys with Parkinson's disease. The findings may change therapeutic practices in humans.
August 31, 2017
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Parkinson: Weight gain after deep brain stimulation
It was already known that people affected by Parkinson's disease, when subjected to deep brain stimulation, gained weight, but it was less clear why that was so. new research has now shown that the weight gain after implant has a multifactorial origin. the study monitored for the first time a group of patients before and after the intervention, assessing cognitive, psychological and behavioral aspects, providing important elements for preventative purposes.
May 4, 2017
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Parkinson's: 2.5 hours of weekly exercise benefits mobility, quality of life
Exercising for at least 2.5 hours every week may help maintain physical health and quality of life for patients with Parkinson's disease, a new study suggests.
March 24, 2017
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Penn researcher searches for common factor linked to smell loss
Studies have shown that loss of the sense of smell can be among the first warning signs of diseases such as Alzheimer's and Parkinson's. now a researcher at the Perelman School of Medicine at the University of Pennsylvania wants to shift the search for clues about this process back even further, to find out if there is a common factor responsible for the loss of smell that may also serve as an early warning signal for a number of neurodegenerative diseases.
May 10, 2017
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People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, research suggests
A new study is strengthening the therapeutic potential for dietary interventions in Parkinson's disease, suggesting that these patients may benefit from a boost in niacin, which is found in some nuts and meat.
January 10, 2017
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Possible Link Between Some Statins and Parkinson's
But the connection was only seen with certain types of the cholesterol-lowering drugs
June 19, 2017
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Pre-clinical study suggests Parkinson's could start in gut endocrine cells
Protein linked to Parkinson's could spread from gut to nervous system
June 15, 2017
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Precision NanoSystems NanoAssemblr™ Chosen for Horizon 2020 Project to develop Novel RNA Therapeutics
Precision NanoSystems NanoAssemblr™ platform has been selected for the controlled manufacture of nanomedicines as part of the multinational B-SMART (Brain-Specific, Modular and Active RNA Therapeutics) translational research project. this €6 million initiative, funded by the EU Horizon 2020 program, aims to use RNA-based therapeutics to silence the production of disease-causing proteins for a range of neurodegenerative disorders, such as Parkinson's, Alzheimer's and Huntington's.
March 29, 2017
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Predicting cognitive deficits in people with Parkinson's disease
Tool may improve clinical trial design and aid in treatment development
June 21, 2017
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Predicting cognitive deficits in people with Parkinson's disease
NIH-funded tool may improve clinical trial design and aid in treatment development.
June 21, 2017
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Protein associated with Parkinson's travels from brain to gut
New laboratory study provides clues on a particular pathway of 'alpha-synuclein' diffusion
January 5, 2017
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Protein in Parkinson's provokes the immune system
Immune cells treat bits of alpha-synuclein as intruders
June 21, 2017
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Protein linked to Parkinson's travels from gut to brain
Over the course of months, clumps of a protein implicated in Parkinson's disease can travel from the gut into the brains of mice, scientists have found.
November 16, 2016
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Misc. - R

Red hair-related gene variant may contribute to link between melanoma and Parkinson's disease
In their paper appearing in the March issue of Annals of Neurology and previously published online, Massachusetts General Hospital (MGH) investigators report that mice carrying the red hair variant of the melanocortin 1 receptor (MC1R) gene have reduced production of the neurotransmitter dopamine in the substantia nigra -- the brain structure in which dopamine-producing neurons are destroyed in Parkinson's disease (PD) -- and are more susceptible to toxins known to damage those neurons.
March 2, 2017
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Regular exercise linked to slower HRQL and mobility decline in PD patients
Exercising 2.5 Hours Per Week Associated with Slower Declines in Parkinson's Disease Patients. According to a new report published in the Journal of Parkinson's Disease
March 23, 2017
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Research suggests how malformed proteins linked to Parkinson's could spread from the gut to the brain
Recent research on Parkinson's disease has focused on the gut-brain connection, examining patients' gut bacteria, and even how severing the vagus nerve connecting the stomach and brain might protect some people from the debilitating disease.
June 15, 2017
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Researchers discover how tau disrupts functioning of nerve cells even before forming tangles
Tau proteins are best known as the proteins that are stacked to form neuronal "tangles" in Alzheimer's patients' brains, but they also play a role in many other brain disorders such as Parkinson's and Huntington's disease. In healthy circumstances, tau proteins are connected to the cytoskeleton of nerve cells, where they support the cells' structural stability. In the nerve cells of patients, however, tau is dislodged from the cytoskeleton and ultimately tangles together to form protein accumulations that disrupt the nerve cell's functioning.
May 19, 2017
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Researchers identify new mechanism that causes hallmark symptoms of Parkinson's disease
A KAIST research team has identified a new mechanism that causes the hallmark symptoms of Parkinson's disease, namely tremors, rigidity, and loss of voluntary movement.
September 26, 2017
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Researchers perform first-ever clinical trial involving genetic screening for Parkinson's disease
In the first ever clinical investigation involving genetic screening for Parkinson's disease, researchers are testing whether the presence of a specific genetic mutation identifies which patients are the best candidates for deep brain stimulation surgery, and whether neurologists should perform that procedure differently based on that genetic information.
September 1, 2017
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Researchers revolutionize brain-computer interfaces using silicon electronics
Today, implanted electrode devices for stimulating the brain are extremely crude devices with only a handful of electrodes that are used to mitigate the effects of Parkinson's, epilepsy, and other neurodegenerative conditions. The number of patients with these devices is merely tens of thousands because of the extreme invasiveness of the implantation process and the large size of the implanted device.
July 10, 2017
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Researchers suggest new theory for how Parkinson's disease develops
The toxic protein behind Parkinson's disease may not spread like an infection from nerve cell to nerve. Instead, say researchers, the protein may simultaneously affect all parts of the nervous system inside and outside of the brain.
March 1, 2017
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Researchers use gene-editing technique to develop new screening tool for Parkinson's disease
A team of researchers at the University of Central Florida is using breakthrough gene-editing technology to develop a new screening tool for Parkinson's disease, a debilitating degenerative disorder of the nervous system. The technology allows scientists in the lab to "light up" and then monitor a brain protein called alpha-synuclein that has been associated with Parkinson's.
June 5, 2017
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Misc. - S

Safe Delivery of Therapeutic Genes by DNA Barcoding
Researchers used small snippets of DNA as barcodes to develop a new technique for rapidly screening the capability of nanoparticles to selectively deliver therapeutic genes to particular organs of the body. this new technique succeeded in accelerating the development and use of gene therapies for Parkinson™ disease, cancer and heart disease.
February 8, 2017
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Scientific discovery may change treatment of Parkinson
When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. a new study shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.
March 22, 2017
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Scientists discover how misfolded proteins can damage cells' energy-producing powerhouses
Working with yeast and human cells, researchers at Johns Hopkins say they have discovered an unexpected route for cells to eliminate protein clumps that may sometimes be the molecular equivalent of throwing too much or the wrong trash into the garbage disposal. Their finding, they say, could help explain part of what goes awry in the progression of such neurodegenerative diseases as Parkinson's and Alzheimer's.
March 3, 2017
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Scientists find way to recover protein structure after chemical denaturation
Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation. The method is based on electrostatic interaction between folded, or denatured, proteins and alumina, which unwrap them. The authors highlight the versatility of the method: it works for both specific molecules and, for the first time ever, multiprotein systems - nobody has been able to recover mixtures of enzymes before.
June 9, 2017
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Scientists grow mini human brains
Scientists in Singapore have made a big leap on research on the 'mini-brain'. These advanced mini versions of the human midbrain will help researchers develop treatments and conduct other studies into Parkinson's Disease and ageing-related brain diseases.
July 29, 2016
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Scientists solve 3-D structure of key defense protein against Parkinson's disease
Scientists have identified the structure of a key enzyme that protects the brain against Parkinson's disease. The result of a decade of work, the research team said that solving the 3-D structure and inner workings of the PINK1 enzyme represented a major breakthrough.
October 5, 2017
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Smart belt helps Parkinson's patients with balance
A vibrating belt and a smartphone app could help reduce falls by assisting people who have balance problems.
August 2, 2017
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Spatial structure of amyloid fibrils linked to Parkinson's disease highly dependent on salt concentration
By combining two-dimensional infrared spectroscopy and atomic force microscopy, Amsterdam researchers have established that the spatial structure of amyloid fibrils related to Parkinson's disease is highly dependent on salt concentration during protein aggregation. the results, published recently in Nature's open access journal 'Scientific Reports', can contribute to an explanation of observed differences in fibril-related pathologies.
February 6, 2017
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SPECT imaging may not be suitable for monitoring Parkinson's disease, study shows
When monitoring Parkinson's disease, SPECT imaging of the brain is used for acquiring information on the dopamine activity. a new study conducted in Turku, Finland, shows that the dopamine activity observed in SPECT imaging does not reflect the number of dopamine neurons in the substantia nigra, as previously assumed.
March 22, 2017
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Statins may not be used for protection against Parkinson's disease
Statins may not be used for protection against Parkinson's disease
June 14, 2017
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Statins may raise the risk of Parkinson's disease
Thousands of people across the United States are diagnosed with Parkinson's disease every year. New research examines the effect of statins on the risk of developing this neurodegenerative disease.
June 15, 2017
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Study finds link between extended use MAO-B inhibitors and slow clinical decline in PD patients
There has long been interest in whether monoamine oxidase type B (MAO-B) inhibitors slow progression of Parkinson's disease (PD) and improve long-term outcomes.
March 6, 2017
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Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease
A study published in the journal Nature Neuroscience, from Nature publishing group, describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease.
September 25, 2017
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Study shows um-PEA as safe and efficacious adjuvant treatment for advanced PD patients
Parkinson disease is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. First described by the English physician James Parkinson two centuries ago, there is yet no cure for PD. Indeed, there is a long list of failed clinical studies based on successful data obtained with exogenous neurotoxin preclinical models
April 12, 2017
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Study uses new approach to model brain connections for understanding Parkinson's disease
Some 10 million people worldwide suffer from Parkinson's disease -- a debilitating condition that causes degeneration of brain nerve cells that control movement. The exact reasons for this degeneration remain unknown.
September 27, 2017
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Study: Abnormal proteins in Alzheimer's, Parkinson's, and Huntington's diseases share similar feature
A Loyola University Chicago study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a similar ability to cause damage when they invade brain cells.
May 23, 2017
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Study: Telemedicine may be as effective as in-person care for people with Parkinson's disease
For people with Parkinson's disease, seeing a neurologist by video conference from their homes may be as effective as their usual in-person care with their local physician, according to a new study published in the August 16, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.
August 17, 2017
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Misc. - T

Targeting Parkinson's-linked protein could neutralize two of the disease's causes
Mouse and human cell studies confirm a common link between proteins and loss of dopamine-making brain cells
February 1, 2017
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This Microsoft wearable is helping Parkinson's patients write again
It's called the Emma Watch, and it vibrates in a specific pattern to stop hand tremors
May 11, 2017
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Thought Processing Concerns Parkinson's Patients
Those with thinking difficulties struggle to follow conversations or recall words
March 18, 2016
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Transcranial stimulation and/or physical therapy improves walking speed in Parkinson's disease
Noninvasive brain stimulation and physical therapy -- alone or in combination -- improve some measures of walking ability in patients with Parkinson's disease (PD), concludes a clinical trial.
June 27, 2017
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Two existing drugs halt neurodegeneration in mice
Researchers have made a major leap forward in the treatment of Alzheimer's and Parkinson's, after identifying two existing drugs that prevented brain cell death in mouse models of neurodegenerative disease.
April 20, 2017
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Two new studies expand understanding of link between PD and gastrointestinal dysfunction
Constipation is one of the most common non-motor related complaints affecting Parkinson's disease (PD) patients. Two important studies from the same research group published in the Journal of Parkinson's Disease expand the understanding of the relationship between PD and gastrointestinal dysfunction. In one study, investigators measured actual colonic dysfunction and compared it to reported constipation. In the other study, researchers tracked the position of an ingested wireless electromagnetic capsule using the novel 3D-Transit system in order to calculate gastrointestinal (GI) regional transit times.
July 31, 2017
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Misc. - U

UAB investigators receive BRAIN Initiative award to study new DBS technology for Parkinson's disease
The University of Alabama at Birmingham has received a BRAIN Initiative grant of $7.3 million over five years from the National Institutes of Health to study new technology that could improve outcomes from deep brain stimulation, an increasingly important treatment for Parkinson's disease and other movement disorders.
October 18, 2016
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Misc. - V

Vercise Gevia Deep Brain Stimulation System with Visual Brain Targeting Software Cleared in Europe
Boston Scientific won the CE Mark of approval, allowing for the introduction of the Vercise Gevia Deep Brain Stimulation System in Europe. The Vercise Gevia is indicated for patients with movement disorders such as Parkinson's, dystonia, and essential tremor, helping to calm down involuntary muscle activity that creates serious quality of life issues.
June 8, 2017
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VIB-KU Leuven researchers identify underlying mechanism in early onset Parkinson's disease
A team of researchers led by Patrik Verstreken (VIB-KU Leuven) have identified an underlying mechanism in early onset Parkinson's. Using flies, mice and patient cells, the team focused on cardiolipin, a fat unique to cells' mitochondria, organelles that produce energy. they demonstrated that reducing the effects of the protein FASN influences the mitochondria, leading to increased cardiolipin levels and reduced Parkinson's symptoms. These results could pave the way to therapies for Parkinson's disease that target lipids.
February 10, 2017
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Viral vectors for gene transfer can travel to distant areas in the brain, study shows
Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells. In a study on mice, a team of researchers from Vetmeduni Vienna for the first time investigated how far these viruses spread in the brain and which cells they infect.
June 16, 2017
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Viral vectors for gene transfer travel longer distances in the brain than thought
Gene transfer as a treatment of neurodegenerative diseases
June 16, 2017
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Misc. - W

Waterlogged brain region helps scientists gauge damage caused by Parkinson's disease
NIH-funded research could aid drug development for the condition.
July 26, 2017
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Waterlogged brain region helps scientists gauge damage caused by Parkinson's disease
Research could aid drug development for the condition
July 26, 2017
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What is survival among patients with Parkinson, Dementia with lewy bodies?
A new article compares survival rates among patients with synucleinopathies, including Parkinson disease, dementia with Lewy bodies, Parkinson disease dementia and multiple system atrophy with parkinsonism, with individuals in the general population.
May 15, 2017
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